Prince William has referenced the King’s cancer diagnosis for the first time since the announcement by Buckingham Palace on Monday.
Arriving at a gala for the London Air Ambulance Service in central London, the Prince of Waleswaved to people gathered outside the venue.
“We really appreciate everyone’s kind messages, thank you,” he said.
Inside, he gave a speech and again thanked everyone for “kind messages”.
“I’d like to take this opportunity to say thank you, also, for the kind messages of support for Catherine and for my father, especially in recent days,” he said.
“It means a great deal to us all. It’s fair to say the past few weeks have had a rather medical focus,” he added, joking that he had come to an air ambulance function to “get away from it all”.
Before he spoke, he was spotted talking to and laughing with Hollywood star Tom Cruise, who is also at the gala tonight.
Prince William was back at work supporting the King on Wednesday, when he hosted a Windsor Castle investiture ceremony.
Prince Harry had been told, like other senior royals, personally by the King about his diagnosis, and quickly boarded a flight from California, spending around 45 minutes at Clarence House on Tuesday before returning on Wednesday.
The King looked relaxed when, as he returned to Sandringham, he was seen in public on Tuesday for the first time since the diagnosis was announced.
His treatment as an outpatient started earlier this week and he has postponed all public-facing duties, although he is continuing with work on his red boxes of state papers.
It is understood this is expected to revert to in-person meetings in two weeks.
William is expected to take on more public duties while his father focuses on treatment.
The gala dinner is raising funds for London’s Air Ambulance Charity’s Up Against Time appeal, which is seeking £15m to replace the service’s helicopter fleet by the autumn.
William is a former air ambulance pilot with the East Anglian Air Ambulance and during the event will meet crew members, former patients and supporters before delivering a short speech.
London’s Air Ambulance Charity was established in 1989 following a growing consensus of opinion that victims of serious accidents were dying because of the delay in expert medical help.
The service pioneered the doctor-on-board model for air ambulances and aims to bring the hospital emergency department to the scene of an incident.