America appears to have hit the three key locations in Iran’s nuclear programme.
They include Isfahan, the location of a significant research base, as well as uranium enrichment facilities at Natanz and Fordow.
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Natanz was believed to have been previously damaged in Israeli strikes after bombs disrupted power to the centrifuge hall, possibly destroying the machines indirectly.
However the facility at Fordow, which is buried around 80 metres below a mountain, had previously escaped major damage.
Details about the damage in the US strikes is not yet known, although Mr Trump said the three sites had been “obliterated”.