A record number of people died of a drug overdose in the US last year, according to government estimates.
The death toll of 93,000 is a big increase from the 72,000 estimate in the previous year, and it means there were more than 250 deaths each day, roughly 11 every hour.
Only two states – New Hampshire and South Dakota – did not see an increase in drug overdose deaths.
Kentucky saw a 54% increase to more than 2,100 and Vermont was up 58% – from 118 to 186, with large increases also seen in South Carolina, West Virginia, and California.
There is no evidence that more Americans started using drugs last year but the deaths were more likely to be among those who were already struggling with their addiction, according to Shannon Monnat, an associate professor of sociology at Syracuse University.
Prof Monnat, who researches geographic patterns in overdoses, said some addicts also told her that, when benefits were extended and evictions were paused as part of government pandemic measures, they had more money to feed their addiction.
Lockdowns and other pandemic-related restrictions left addicts isolated and made it more difficult for them to get treatment.
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Needle exchange programmes, opioid substitution therapy, safe injection sites, support groups, and therapy sessions were all curtailed by social distancing and stay-at-home orders.
Image: Jordan McGlashen, left, and his brother, Collin
Jordan McGlashen died after overdosing on heroin and fentanyl in his Michigan apartment in May last year, a day before his 39th birthday.
The musician had seen his father die of cancer a few months earlier and had also lost his job in the early days of the pandemic.
His brother Collin said: “He was alone, and suffering emotionally and felt like he had to use again.”
“Someone can be doing really well for so long and then, in a flash, deteriorate.
“It was really difficult for me to think about the way in which Jordan died.”
Decades ago, overdoses were driven by prescription painkillers but they were overtaken by heroin, with around 7,200 deaths in 1970.
By 1988, crack cocaine was the drug of choice and there were about 9,000 overdose deaths.
Then fentanyl took over and it is thought to have been involved in more than 60% of overdose deaths last year, with opioids overall blamed for 74.7%.
Fentanyl, which is 80-100 times stronger than morphine, was made to treat pain from illnesses such as cancer but it is now mixed with other drugs and sold illicitly.
It is too soon for national figures covering 2021 but state data so far indicates that fentanyl is continuing to push up the number of drug overdose deaths.
Rhode Island reported 34 in January and 37 in February – the most for those months in at least five years.
Prof Monnat said: “What’s really driving the surge in overdoses is this increasingly poisoned drug supply.
“Nearly all of this increase is fentanyl contamination in some way. Heroin is contaminated. Cocaine is contaminated. Methamphetamine is contaminated.”
Dozens of supporters were outside court as the man accused of fatally shooting the chief executive of UnitedHealthcare made his first appearance.
Luigi Mangione has pleaded not guilty to multiple counts of murder following the 4 December killing of Brian Thompson, 50, outside a midtown Manhattan hotel.
The 26-year-old is accused of ambushing and shooting the executive as he walked to an investor conference.
Image: Luigi Mangione supporters stand outside the Supreme Court. Pic: AP Photo/Stefan Jeremiah
Dozens of people who showed up in court to support the suspect including former army intelligence analyst Chelsea Manning who was jailed for stealing classified diplomatic cables.
Dozens more queued in the hallway.
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Mangione is also facing federal charges that could carry the possibility of the death penalty.
The judge set a deadline of 9 April to submit pre-trial motions.
Image: Luigi Mangione is accused of fatally shooting Brian Thompson. Pic: Steven Hirsch/New York Post via AP
In addition to the New York cases, Mr Mangione also faces charges of forgery, carrying firearms without a licence, and other counts in Pennsylvania, where authorities arrested him at a McDonald’s.
Police say he was in possession of a gun, bullets, multiple fake IDs and a handwritten document that expressed “ill will” towards corporate America.
He is being held in a Brooklyn jail alongside several other high-profile defendants, including music mogul and rapper Sean “Diddy” Combs, and disgraced crypto entrepreneurSam Bankman-Fried.
The killing prompted some to voice their resentment at US health insurers, with Mangione attracting a cult following.
A poll taken in the wake of the shooting showed most Americans believe health insurance profits and coverage denials were partly to blame for the incident.
Sir Keir Starmer and Emmanuel Macron have not “done anything” to end the Ukraine war, US President Donald Trump has said.
He called the French president a “friend of mine” and the UK leader a “nice guy” but said Russia had only agreed to negotiate “because of me”.
Mr Trump made the comments days before both leaders visit the White House for a meeting in which they must try to press Ukraine‘s case while keeping the US leader onside.
Image: Sir Keir Starmer and Emmanuel Macron in Paris: Pic: Number 10/Flickr
The president also continued his criticism of Volodymyr Zelenskyy, saying he had “no cards” to play.
“I’ve been watching for years, and I’ve been watching him negotiate with no cards. He has no cards. And you get sick of it. You just get sick of it. And I’ve had it,” he told a Fox radio show.
The comments come after he recently called the Ukrainian leader a “dictator without elections” – apparently in response to Mr Zelenskyy saying his US counterpart was living in a “disinformation space” after Mr Trump claimed Ukraine had started the war.
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They were intended to set the stage for future negotiations on ending the war, which started when Russia launched a full-scale invasion three years ago.
Speaking on Friday evening, Mr Trump denied speculation he could visit Moscow for talks on 9 May – the day Russia celebrates its victory over the Nazis.
Image: President Trump speaks in the Oval Office on Friday. Pic: Reuters
Mr Trump also told reporters the Russian and Ukrainian leaders needed to “work together” to end the war.
However, the US has already dealt a huge blow to Kyiv’s position in any future talks.
Seven people have been injured, three critically, after a suspected gas explosion at a popular beach resort in Hawaii, according to police and video footage.
The injured range in age from 18 to 74, police said, following Thursday night’s blast in a barbeque grill area at The Whaler.
The explosion left a pile of debris at the resort in Kaanapali Beach, a popular tourist area near Lahaina, which almost completely burned in a deadly wildfire in 2023.
No one was forced to leave the area because of the blast, the Maui Police Department said.
Its early investigations pointed to liquefied petroleum gas (LPG), used in barbecue grills in the resort’s common area, being involved in the explosion, the force said.
Video of the area shared on social media shows an explosion happening outdoors near a swimming pool, scattering debris near the beach.