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A team of researchers at the Perelman School of Medicine at the University of Pennsylvania has discovered that obese mice, treated with the cytokine (a category of proteins) known as TSLP, reported significant fat and weight loss. Described as an “unforeseen finding,” researchers also said that the fat loss was in no way related to decreased food intake or faster metabolism. The treatment revealed, “TSLP prompted the immune system to release lipids through the skin’s oil-producing sebaceous glands.” 

The study is led by Taku Kambayashi, Associate Professor of Pathology and Laboratory Medicine at the University of Pennsylvania. He was joined by Ruth Choa, a fourth-year PhD medical student. Kambayashi said that despite being an unexpected discovery, the team has demonstrated that fat loss was possible by secreting calories from the skin in the form of energy-rich sebum. The professor added that the findings of the animal experiment also show that this could develop into a model for the treatment of obesity among people.  

Kambayashi said that they never thought the TSLP would have any impact on obesity itself. What they set out for was to find out if it impacted insulin resistance. “We thought that the cytokine could correct Type 2 diabetes, without actually causing the mice to lose any weight,” he said.

In order to see the effect of TSLP on Type 2 diabetes, the researchers administered on obese mice a viral vector to increase their bodies’ TSLP levels. Four weeks after the mice were administered injections, the team found that TSLP, besides affecting their diabetes risk, also reduced obesity in them. Compared to TSLP-treated mice, the control group continued to gain weight. The TSLP-treated mice lost 20 grams, going from 45 to just 25 grams in 28 days, the team said. 

Not just that, while the mice reported weight and fat loss, Kambayashi assumed that TSLP was perhaps sickening them. Upon further testing, the group realised that the mice receiving TSLP treatment were also eating 20 to 30 percent more. Besides, they also had similar energy expenditures, base metabolic rates, and activity levels compared to their non-treated counterparts.

Could this work on Humans?

The authors of the study said that in humans, shifting sebum release into “high gear” could feasibly lead to the “sweating of fat” and weight loss.

Kambayashi’s group next plans to test this hypothesis. He said that he doesn’t think humans naturally control their weight by regulating sebum production. “We may be able to hijack the process and increase sebum production to cause fat loss,” he said.


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SpaceX Rocket Launches 28 Starlink Satellites, Makes 26th Booster Reuse

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SpaceX Rocket Launches 28 Starlink Satellites, Makes 26th Booster Reuse

SpaceX launched its next batch of Starlink V2 Mini satellites on a Falcon 9 rocket launch from Cape Canaveral Space Force Station shortly before midnight on Tuesday. The Starlink 10-29 mission added another 28 satellites into the low Earth orbit megaconstellation. A SpaceX Falcon 9 rocket lifted off at 11:37 p.m. EDT (0337 GMT on July 30) from Space Launch Complex 40 (SLC-40) at Cape Canaveral Space Force Station in Florida.

After a nine minute climb into space, the 28 Starlink broadband internet satellites (group 10-29) were on track to be deployed into their intended orbit. After payload deployment, the Falcon 9 first stage separated and successfully landed on the ocean-going droneship “Just Read the Instructions”, positioned in the Atlantic Ocean.

This mission notably marked the 26th flight for the Falcon 9’s first stage, booster B1069, which has been a part of missions include diverse payloads such as CRS-24, Eutelsat HOTBIRD 13F, OneWeb 1, SES-18 and SES-19, alongside 22 other Starlink deployments.

According to satellite tracker Jonathan McDowell, the Starlink constellation now includes over 8,050 active satellites (out of more than 9,300 launched since 2018). The growing fleet is intended to provide high-speed internet worldwide, and each launch like this one adds capacity and coverage. The mission also highlights SpaceX’s extraordinary launch cadence and technical progress.

It was the company’s 96th launch of 2025, reflecting a packed schedule and intense operational tempo. Two more missions were scheduled later that week — another Starlink launch from California and NASA’s Crew-11 flight to the International Space Station. The repeated reuse of boosters (as evidenced by B1069’s 26 flights) is central to lowering costs and sustaining this ambitious cadence.

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Smithsonian Air and Space Museum Reopens with SpaceX Rocket, Mars Habitat and More

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Smithsonian Air and Space Museum Reopens with SpaceX Rocket, Mars Habitat and More

Hundreds waited at the ready outside the Smithsonian’s National Air and Space Museum on Monday (July 28), when “the doors opened for access to five featured and newly renovated galleries that capture the history, contemporary status, and futuristic vision of aviation and space exploration. These refurbished spaces showcase a mix of historic and high-tech artifacts such as John Glenn’s “Friendship 7” capsule, pieces of a SpaceX Falcon 9 rocket, and a 3D-printed Mars habitat. Visitors were among the first to experience a sweeping display of innovation, housed within the museum’s revitalised main building on the National Mall in Washington, D.C.

Smithsonian’s $900M Overhaul Brings Futuristic Space Exhibits and Aviation History to Life

As per a Smithsonian statement, the reimagined exhibits are part of a $900 million full-building transformation launched in 2018, scheduled for completion by July 2026—the museum’s 50th anniversary. This phase marks the second group of reopened galleries since the start of 2022. After a three-year closure, the north entrance opened for the first time, leading visitors through a newly wing-shaped vestibule and into “Boeing Milestones of Flight Hall”, now with improved lighting, digital screens, and iconic artefacts.

Next to it, a new “Futures in Space” gallery showcases domestic exhibitions from private space companies like SpaceX, Blue Origin, Virgin Galactic, and Axiom Space. Rather than a chronological or program-based layout, the gallery explores philosophical and practical questions about space: Who decides who goes? Why do we venture out? What will we do once we arrive? The immersive layout blends historical items, contemporary designs, and even pop culture references.

The museum has reopened galleries such as “Barron Hilton Pioneers of Flight”, “World War I: The Birth of Military Aviation”, and “Allan and Shelley Holt Innovations Gallery”, and the upgraded Lockheed Martin IMAX Theatre, praised as educational and inspirational.

Despite free entry, the Smithsonian Museum reopened to more than 6,000 guests, who must pick up timed-entry passes in order to better manage crowd flow.

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NASA’s Solar Observatory Sees Two Eclipses in One Day

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NASA’s Solar Observatory Sees Two Eclipses in One Day

NASA’s Solar Dynamics Observatory (SDO) has witnessed and recorded an unprecedented phenomenon of two solar eclipses in one day on July 25, 2025. These two eclipses took place only hours apart that day, and were photographed by SDO instruments pointed up and away from the Sun in geosynchronous orbit. First, around 2:45 UTC, the Moon passed between SDO and the Sun. Then, starting at about 6:30 UTC, Earth itself eclipsed the Sun from SDO’s point of view, with the Sun disappearing behind our planet shortly before 8:00 UTC. Since launching in 2010, SDO has continuously monitored the Sun’s activity, from solar flares to magnetic fields, helping forecasters predict space weather.

Moon Transit

According to NASA, SDO orbits Earth in a high geosynchronous orbit, so it has an almost constant view of the Sun. On July 25, this vantage point captured a partial solar eclipse as the Moon passed between the spacecraft and the Sun. NASA’s mission team had predicted this “lunar transit” would cover about 62% of the solar disk. Indeed, the Moon’s silhouette moved slowly across the Sun (around 2:45–3:35 UTC), blocking roughly two-thirds of the bright disk at maximum. The observatory’s ultraviolet telescope (AIA) recorded the event, revealing the Sun’s lower atmosphere and coronal loops around the sharply defined lunar edge. This transit was the deepest lunar eclipse SDO saw in 2025.

Earth’s Eclipse from Space

Hours later, on the same day, Earth itself passed between SDO and the Sun. Beginning around 6:30 UTC on July 25, our planet fully blocked the observatory’s view of the solar disk. This occurred during SDO’s regular eclipse season (a roughly three-week period twice each year when Earth’s orbit crosses the satellite’s line of sight). The total eclipse lasted until shortly before 8:00 UTC. In SDO’s images, Earth’s shadow has a fuzzy edge because our atmosphere scatters sunlight, in contrast to the Moon’s crisp eclipse.

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