Connect with us

Published

on

A coronavirus infection presents a much higher risk of developing a blood clot than a first dose of either the AstraZeneca or the Pfizer jab, a study has found.

The research used findings from more than 29 million people who were vaccinated with first doses of either jab.

The study showed although there was an increased risk of having a blood clot after having the first doses of either vaccine, it was much greater in someone who had tested positive for COVID-19.

The researchers are fully independent from the University of Oxford team that worked with AstraZeneca to develop that particular vaccine.

Fears over blood clots have led to the restricted use of the Oxford AstraZeneca vaccine in a number of countries.

The researchers, writing in the British Medical Journal, found for short time intervals after the first does there are increased risks of some blood, or blood-vessel, related events leading to hospitalisation or death.

However, they also wrote that that the risk of these adverse events is substantially higher and for a longer period of time, following infection from coronavirus.

More on Covid-19

Julia Hippisley-Cox, professor of clinical epidemiology and general practice at the University of Oxford, lead author of the paper, said: “People should be aware of these increased risks after COVID-19 vaccination and seek medical attention promptly if they develop symptoms, but also be aware that the risks are considerably higher and over longer periods of time if they become infected with SARS-CoV-2.”

All of the coronavirus vaccines currently in use have been tested in randomised clinical trials, which are unlikely to be large enough to detect very rare adverse events.

When rare events are uncovered, regulators perform a risk-benefit analysis of the medicine to compare the risk of the adverse reaction, such as a blood clot, against the benefits of avoiding the disease – in this case COVID-19.

Follow the Daily podcast on Apple Podcasts, Google Podcasts, Spotify, Spreaker

For this paper, the researchers used routinely collected electronic health records to evaluate the short-term risks (within 28 days) of hospital admission from blood clots.

They used data collected from across England between 1 December 2020 and 24 April 2021.

Professor Hippisley-Cox said: “This research is important as many other studies, while useful, have been limited by small numbers and potential biases. Electronic healthcare records, which contain detailed recording of vaccinations, infections, outcomes and confounders, have provided us with a rich source of data with which to perform a robust evaluation of these vaccines, and compare to risks associated with COVID-19 infection.”

The research was carried out by a team from the University of Oxford, University of Leicester, Guys and St Thomas’ NHS Foundation Trust, the Intensive Care National Audit & Research Centre, the London School of Hygiene and Tropical Medicine, the University of Cambridge, the University of Edinburgh and the University of Nottingham.

Continue Reading

UK

Rachel Reeves to head to Washington amid hopes of US trade deal

Published

on

By

Rachel Reeves to head to Washington amid hopes of US trade deal

Rachel Reeves will pledge to “stand up for Britain’s national interest” as she heads to Washington DC amid hopes of a UK/US trade deal.

The chancellor will fly to the US capital for her spring meetings of the International Monetary Fund (IMF), the first of which began on Sunday.

During her three-day visit, Ms Reeves is set to hold meetings with G7, G20 and IMF counterparts about the changing global economy and is expected to make the case for open trade.

Politics latest: Tributes paid to Pope Francis

Her visit comes after Donald Trump imposed blanket 10% tariffs on all imports into the US, including from the UK, and as talks about reaching a trade deal intensified.

The chancellor will also hold her first in-person meeting with her US counterpart, treasury secretary Scott Bessent, about striking a new trade agreement, which the UK hopes will take the sting out of Mr Trump’s tariffs.

In addition to the 10% levy on all goods imported to America from the UK, Mr Trump enacted a 25% levy on car imports.

Ms Reeves will also be hoping to encourage fellow European finance ministers to increase their defence spending and discuss the best ways to support Ukraine in its war against Russia.

Read more:
Mission: Impossible? Chancellor heads to the IMF

Starmer and the King pay tribute to Pope Francis

Speaking ahead of her visit, Ms Reeves said: “The world has changed, and we are in a new era of global trade. I am in no doubt that the imposition of tariffs will have a profound impact on the global economy and the economy at home.

“This changing world is unsettling for families who are worried about the cost of living and businesses concerned about what tariffs will mean for them. But our task as a government is not to be knocked off course or to take rash action which risks undermining people’s security.

“Instead, we must rise to meet the moment and I will always act to defend British interests as part of our plan for change.

“We need a world economy that provides stability and fairness for businesses wanting to invest and trade, more trade and global partnerships between nations with shared interests, and security for working people who want to get on with their lives.”

Continue Reading

UK

Murder arrest after woman stabbed to death in Enfield – as victim named

Published

on

By

Murder arrest after woman stabbed to death in Enfield - as victim named

A woman who was stabbed to death in north London has been named by police – as a man was arrested on suspicion of murder.

Pamela Munro, 45, was found with a stab wound and died at the scene in Ayley Croft, Enfield, on Saturday evening, the Metropolitan Police said.

A 29-year-old man was arrested on suspicion of murder on Monday and is in custody, the force added.

Detective Chief Inspector Neil John said: “Investigating officers have worked relentlessly across the weekend to investigate the circumstances around Pamela’s death.

“We continue to support her family who are understandably devastated.”

GVs from SN footage on 20/04/2025 at scene of murder on 19/04/2025 of woman at Gainsborough House, Ayley Croft, Enfield in north London.
Ingest 25 NM25 SKY SAF ENFIELD MURDER GVS ENFIELD 2045
Image:
Police at the scene at Ayley Croft in Enfield

Read more from Sky News:
Fresh appeal over student’s murder
100 firefighters battle flats blaze

The Met Police has asked anyone with information or who was driving through Ayley Court between 6.30pm and 7.30pm on Saturday and may have dashcam footage to contact the force.

Continue Reading

UK

‘British man’ dies after being dragged out of police station in Ecuador – reports

Published

on

By

'British man' dies after being dragged out of police station in Ecuador - reports

A “British man” has died after being beaten and set on fire by a mob in Ecuador, according to reports by media in the South American country.

According to reports, the man – who has not been officially identified – had been detained by police after being accused of being involved in a fatal shooting.

Ecuadorian news outlet Ecuavisa reported that the man had been taken to a police station Playas del Cuyabeno, a remote village in the Amazon rainforest.

While there, a group broke into the station and took the man away. He was then set on fire in the street, it is reported, and died from his burns.

Playas del Cuyabeno
Image:
The incident reportedly happened in the Playas del Cuyabeno area of Sucumbios province

Another local report, from EXTRA.ec, said that specialist police units had been slow to arrive due to the geographical conditions of the area – which is accessible by river.

Read more from Sky News:
IDF finds ‘failings’ over attack on aid workers
Pope blesses Easter crowds from popemobile

According to reports, police officers at the station apparently decided they could not intervene when the mob arrived out of concerns for their own safety.

It is understood the UK Foreign Office is following up reports about the incident and working with local authorities to confirm the details.

Continue Reading

Trending