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Even as the nightmare involving deadly new variants of COVID-19 had started making people gloomy, the arrival of vaccines changed the grim narrative and infused a lot of optimism. But the need for treatments for those at high risk of severe illness after being infected with COVID-19 and people with a weak immune system who may not generate a robust response to the vaccines was always felt. In the last few months, there has been significant progress in developing effective antibody-based therapies. At present, three such drugs have received emergency use approval from the US Food and Drug Administration.

One such drug, Sotrovimab, was developed by GlaxoSmithKline and Vir Biotechnology after a large collaborative study by scientists found a natural antibody in the blood of a SARS survivor, back in 2003 that has a remarkable breadth and efficacy.

This antibody is called S309. Experiments revealed that it neutralised all known SARS-CoV-2 strains, including the newly emerged mutants that can now “escape” from previous antibody therapies as well as the closely related original SARS-CoV virus.

According to a report in SciTechDaily, Jay Nix, leader of the Molecular Biology Consortium based at Berkeley Lab’s Advanced Light Source (ALS), performed X-ray crystallography on samples of antibodies from survivors during an early phase of the study. This helped generate structural maps of how these antibodies merge with the SARS-CoV-2 spike protein, which, in turn, allowed developers to select the most promising antibodies. Following the lab results, they designed Sotrovimab.

In May, the FDA gave Sotrovimab emergency use approval after trials showed that there was an 85 percent reduction in hospitalisation or death rates, compared with placebo, in people with mild to moderate COVID-19 infections, who underwent the therapy.

However, taking into considerations that new mutations could arise, the researchers began a follow-up study to explore such antibodies further. In the process, they identified one antibody with unparalleled potency. Nix said that this antibody appears to “neutralise all known sarbecoviruses — the genus of coronaviruses that cause respiratory infections in mammals”, making it “more difficult for a new strain to escape”.

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Rare Titan Shadow Transits Will Sweep Across Saturn in Summer 2025

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June 30, 2025

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Rare Titan Shadow Transits Will Sweep Across Saturn in Summer 2025

Saturn’s largest moon Titan will cast its shadow across the planet’s surface in a rare spectacle this summer. Over the coming months, observers on Earth may see a dark “hole” move across Saturn’s disk as Titan passes in front of the planet. This event is tied to a special alignment: roughly every 15 years, Saturn’s rings become edge-on to our view (a ring-plane crossing or equinox). Indeed, in March 2025 the rings briefly vanished as they lined up edge-on, setting the stage for Titan’s shadow to loom large on Saturn’s globe. After this year’s transit season, the configuration won’t recur until about 2040, making these transits uniquely unmissable.

Saturn’s Equinox and Titan’s Transits

According to Space.com, right now Saturn is near its equinox, meaning its tilted rings are edge-on to Earth. This geometry allows Titan’s shadow – a dark spot on Saturn – to sweep across the planet’s face, much like a lunar eclipse but on Saturn. Titan orbits Saturn about every 16 days, so during this alignment we can see its shadow cross Saturn’s disk repeatedly. In fact, roughly ten Titan shadow-transit events are expected during 2025. Three have already occurred (most recently on June 16), and seven more are forecast from July through early October 2025. When visible, each transit looks like a moving dark spot (a “hole”) on Saturn’s bright disk.

Viewing the Titan Shadow Transits

These transits are faint and require planning. A good telescope (at least 200× magnification) is needed to see Titan and its shadow. For viewers in North America, Saturn will be low in the pre-dawn sky during the event dates. According to Sky & Telescope, the remaining 2025 transit dates are July 2, July 18, August 3, August 19, September 4, September 20 and October 6 (local viewing times vary by location).

Early-season events last several hours, but the crossings shorten as the year goes on: by Oct. 6 the shadow is only visible briefly at the exact mid-transit moment. Observers should consult astronomy software and aim for clear skies on those dates, as any clouds or mist will obscure the subtle shadow.

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NASA’s Chandra Reveals Stunning Multi-Wavelength Image of Andromeda Galaxy

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June 30, 2025

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NASA’s Chandra Reveals Stunning Multi-Wavelength Image of Andromeda Galaxy

NASA’s Chandra X-ray Observatory provides a new look at the Andromeda galaxy in this multi-wavelength image that includes X-ray, ultraviolet, optical, infrared, and radio images and illustrates the “collaboration of light” across the spectrum. The structure and future fate of the Milky Way are modelled with the help of Andromeda, which is 2.5 million light years away. This combined image not only shows high-energy radiation from a supermassive black hole but also provides a clear view of the arms and core of M31 in remarkable detail. The light is transformed into a sound with a sonification video, bringing another level of sensation.

Chandra X-ray Data Reveals Black Hole Flares and Dark Matter Legacy in New View of Andromeda

As per NASA’s Chandra team, the X-ray observations — alongside data from ESA’s XMM-Newton, NASA’s GALEX and Spitzer, Planck, IRAS, COBE, Herschel, and more — reveal distinct galactic features. Notably, a flare detected in 2013 from Andromeda’s supermassive black hole showed enhanced X-ray emission. The data also honours astronomer Vera Rubin, whose M31 rotation studies led to the first convincing evidence for dark matter. Rubin is now commemorated on a 2025 U.S. quarter.

Among the release features is a signature sonification, with different categories of light — X-ray, ultraviolet, optical, infrared, and radio — translated into sound tones. Volume is controlled by brightness, pitch by frequency position. The result is a sound map of the galaxy’s internal structure.

The Chandra programme for NASA’s Science Mission Directorate in Washington is managed by NASA’s Marshall Space Flight Centre in Huntsville, Alabama. Chandra’s overseer is the Smithsonian Astrophysical Observatory in Cambridge, Massachusetts.

With this updated M31 panorama in hand, astronomers are in for a beautiful sight, but the broader population is also treated to a sight and sound experience that transports us to our Milky Way’s closest galactic neighbour.

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Could These Meteorites Be from Mercury? New Research Hints at Rare Discovery

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June 30, 2025

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Could These Meteorites Be from Mercury? New Research Hints at Rare Discovery

Scientists have observed whether the meteorites can reach Earth from Mercury. Over thousands of meteorites from Mars and the Moon have been observed, but none have been from Mercury, despite it being a nearby rocky planet. A new study revealed Icarus suggests two meteorites, Ksar Ghilane 022 and Northwest Africa 15915, could belong to Mercurian origin. Such a kind of meteorite can offer a realistic opportunity to study the material of the surface of the planet, if the technical challenges and the cost of sending a spacecraft to Mercury are met.

New Meteorite Samples Show Strong Similarities

As per the new studies reported to Physics.org , Meteorite NWA 7325 and aubrites in the past were considered to be possibly from Mercury. However, the mineral composition of their samples has inconsistencies with the known surface data from the Messenger mission of NASA. Aubrites formed on a planet similar in size to Mercury, lacking spectral and chemical similarities, and further weakened as Mercurian fragments.

Ksar Ghilane 022 and NWA 15915, the new samples, share many traits of Mercury crust, with olivine, oldhamite, pyroxene, and minor albitic plagioclase. The oxygen composition of these matched with the aubrites, signalling a similar planetary origin and putting them among strong Mercurian members.

Key Differences Raise Scientific Questions

There are key differences even after that, and the two meteorites contain very little plagioclase than on the Mercury surface, and are about 4,528 million years older than Mercury’s surface material. If they are from Mercury, there is a possibility that they can represent an ancient crust which is no longer visible on the planet.

Future Missions and Scientific Verification

Relating a meteorite to a particular planet is quite difficult without direct samples. BepiColombo missions are orbiting Mercury currently, and can offer valuable insights to confirm meteorites source. Mercurian meteorites can get valuable insights into the formation, composition and history of the planet. There are further findings to be presented at the Meteoritical Society Meeting 2025 in Australia.

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