Four amateur astronauts are due to spend about three days in orbit in a world first, after they blasted off from the Kennedy Space Centre in Florida on Wednesday evening.
The Inspiration4 mission, backed by SpaceX, was organised by entrepreneur Jared Isaacman, who is also one of the passengers.
They are the first all-civilian crew ever to circle the Earth from space.
During their trip, those on board will carry out a series of science experiments before returning home.
So who are the four crew members, how did they get there and what will happen in the next 72 hours or so.
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A giant leap in commercial space travel
Who are the amateur astronauts?
The four people aboard the Dragon capsule are Jared Isaacman, Hayley Arceneaux, Chris Sembroski, and Dr Sian Proctor.
Mr Isaacman is the man behind the mission, and paid an undisclosed sum to get the project off the ground.
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The 38-year-old made his money with a payment processing company – like SpaceX head Elon Musk – and now also operates a private air force.
Image: Jared Isaacman. Pic: Inspiration4/John Kraus
An experienced pilot, he wants the journey to raise awareness for St Jude’s Children’s Research Hospital in Memphis, Tennessee.
The other three members of the crew were selected according to Mr Isaacman’s conditions.
Hayley Arceneaux, 29, is an employee of St Jude’s, and had cancer during her childhood.
Taking someone from the hospital was a condition from Mr Isaacman.
Ms Arceneaux, a physician’s assistant, is the first person to travel to space with a prosthesis – part of her right femur was replaced by a metal rod during a bone cancer battle at the age of 10.
Dr Proctor, 51, is an entrepreneur and trained pilot herself.
She won her seat through a competition based on a set of business-related tasks.
Image: The four space tourists have defined roles. Pic: Inspiration4/John Kraus
The scientist previously applied for NASA‘s astronaut programme but was unsuccessful – but is now in space.
Last up is Chris Sembroski, 42, a US Air Force veteran who now works for Lockheed Martin.
He was selected from a lottery of people who donated to St Jude’s – a competition which received around 72,000 entries.
What are their roles?
The four space tourists have defined roles, according to their backgrounds.
They have been branded leadership, hope, prosperity and generosity.
Mr Isaacman is leadership, and he will be the mission commander in charge of the operation.
Hope is Ms Arceneaux, who will act as medical officer and will help with experiments being carried out – many of which are medically based.
Image: Dr Proctor unsuccesfully applied to be a NASA astronaut. Pic: Inspiration4/John Kraus
Dr Proctor is prosperity and the mission pilot. She will support Mr Isaacman.
Generosity is represented by Mr Sembroski, who is the mission specialist and will help “manage payload, science experiments, communications to mission control and more”.
What will they do?
Most of the experiments being carried out by the crew are “to increase humanity’s knowledge on the impact of spaceflight on the human body”.
SpaceX, the Translational Research Institute for Space Health (TRISH) at Baylor College of Medicine in Houston, Texas, and the Weill Cornell Medicine in New York City will analyse the data collected.
What experiments will they do
Collecting “research-grade ECG activity, movement, sleep, heart rate and rhythm, blood oxygen saturation, cabin noise and light intensity”
Test behavioural and cognitive function using computer software
Ultrasound scans for organs to see if non-experts can get good quality image and see how spaceflight affects the body
Draw and test blood to see how the immune system functions in space
Testing motor function before and after the flight
How is the ship controlled?
The crew are aboard a Dragon capsule, a reusable pod developed by SpaceX.
It can seat up to seven people, and has been to the International Space Station 25 times – 10 of which were repeat journeys.
Image: The Dragon capsule has room for seven people and solar panels to provide power
It is capable of carrying 365lbs (166kg) of cargo, which is being used for scientific equipment and crew essentials on this journey.
Solar panels on the outside of the craft are used to generate power for the capsule and crew.
Image: The touchscreen control panels in the capsule allow the crew to monitor telemetry
The vessel is largely automatically controlled, with a set of large touch screens instead of the traditional-looking dashboard of buttons, levers and toggles for the pilots to observe.
The pilots can also take control of the capsule with the touchscreens.
Sixteen Draco thrusters are used to direct the vehicle after it separates from the take-off rocket, and it has a set of parachutes for landing.
How are they getting back?
Image: A splashdown of a Dragon capsule. Pic: NASA
After the orbiting is complete, the capsule will head back to Earth.
According to the official plan, this will culminate in a “soft water landing” off the coast of Florida.
After re-entering our planet’s atmosphere, two “drogue” parachutes are deployed, before four main canopies are released.
The crew and vessel will then be retrieved from the water.
While the UK’s FTSE 100 closed down 1.55% and the continent’s STOXX Europe 600 index was down 2.67% as of 5.30pm, it was American traders who were hit the most.
All three of the US’s major markets opened to sharp losses on Thursday morning.
Image: The S&P 500 is set for its worst day of trading since the COVID-19 pandemic. File pic: AP
By 8.30pm UK time (3.30pm EST), The Dow Jones Industrial Average was down 3.7%, the S&P 500 opened with a drop of 4.4%, and the Nasdaq composite was down 5.6%.
Compared to their values when Donald Trump was inaugurated, the three markets were down around 5.6%, 8.7% and 14.4%, respectively, according to LSEG.
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Worst one-day losses since COVID
As Wall Street trading ended at 9pm in the UK, two indexes had suffered their worst one-day losses since the COVID-19 pandemic.
The S&P 500 fell 4.85%, the Nasdaq dropped 6%, and the Dow Jones fell 4%.
It marks Nasdaq’s biggest daily percentage drop since March 2020 at the start of COVID, and the largest drop for the Dow Jones since June 2020.
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5:07
The latest numbers on tariffs
‘Trust in President Trump’
White House press secretary Karoline Leavitt told CNN earlier in the day that Mr Trump was “doubling down on his proven economic formula from his first term”.
“To anyone on Wall Street this morning, I would say trust in President Trump,” she told the broadcaster, adding: “This is indeed a national emergency… and it’s about time we have a president who actually does something about it.”
Later, the US president told reporters as he left the White House that “I think it’s going very well,” adding: “The markets are going to boom, the stock is going to boom, the country is going to boom.”
He later said on Air Force One that the UK is “happy” with its tariff – the lowest possible levy of 10% – and added he would be open to negotiations if other countries “offer something phenomenal”.
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3:27
How is the world reacting to Trump’s tariffs?
Economist warns of ‘spiral of doom’
The turbulence in the markets from Mr Trump’s tariffs “just left everybody in shock”, Garrett Melson, portfolio strategist at Natixis Investment Managers Solutions in Boston, told Reuters.
He added that the economy could go into recession as a result, saying that “a lot of the pain, will probably most acutely be felt in the US and that certainly would weigh on broader global growth as well”.
Meanwhile, chief investment officer at St James’s Place Justin Onuekwusi said that international retaliation is likely, even as “it’s clear countries will think about how to retaliate in a politically astute way”.
He warned: “Significant retaliation could lead to a tariff ‘spiral of doom’ that could be the growth shock that drags us into recession.”
It comes as the UK government published a long list of US products that could be subject to reciprocal tariffs – including golf clubs and golf balls.
Running to more than 400 pages, the list is part of a four-week-long consultation with British businesses and suggests whiskey, jeans, livestock, and chemical components.
Meanwhile, Prime Minister Sir Keir Starmer said on Thursday that the US president had launched a “new era” for global trade and that the UK will respond with “cool and calm heads”.
It also comes as Canadian Prime Minister Mark Carney announced a 25% tariff on all American-imported vehicles that are not compliant with the US-Mexico-Canada trade deal.
He added: “The 80-year period when the United States embraced the mantle of global economic leadership, when it forged alliances rooted in trust and mutual respect and championed the free and open exchange of goods and services, is over. This is a tragedy.”
Tanking stock markets, collapsing world orders, devastating trade wars; economists with their hair ablaze are scrambling to keep up.
But as we try to make sense of Donald Trumps’s tariff tsunami, economic theory only goes so far. In the end this surely is about something more primal.
Power.
Understanding that may be crucial to how the world responds.
Yes, economics helps explain the impact. The world’s economy has after all shifted on its axis, the way it’s been run for decades turned on its head.
Instead of driving world trade, America is creating a trade war. We will all feel the impact.
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0:58
PM will ‘fight’ for deal with US
Donald Trump says he is settling scores, righting wrongs. America has been raped, looted and pillaged by the world trading system.
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But don’t be distracted by the hyperbole – and if you think this is about economics alone, you may be missing the point.
Above all, tariffs give Donald Trump power. They strike fear into allies and enemies, from governments to corporations.
This is a president who runs his presidency like a medieval emperor or mafia don.
It is one reason why since his election we have seen what one statesman called a conga line of sycophants make their way to the White House, from world leaders to titans of industry.
The conga line will grow longer as they now redouble their efforts hoping to special treatment from Trump’s tariffs. Sir Keir Starmer among them.
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President Trump’s using similar tactics at home, deploying presidential power to extract concessions and deter dissent in corporate America, academia and the US media. Those who offer favours are spared punishment.
His critics say he seeks a form power for the executive or presidential branch of government that the founding fathers deliberately sought to prevent.
Whether or not that is true, the same playbook of divide and rule through intimidation can now be applied internationally. Thanks to tariffs
Each country will seek exceptions but on Trump’s terms. Those who retaliate may meet escalation.
This is the unforgiving calculus for governments including our own plotting their next moves.
The temptation will be to give Trump whatever he wants to spare their economies, but there is a jeopardy that compounds the longer this goes on.
Image: Could America’s traditional allies turn to China? Pic: AP
Malcolm Turnbull, the former Australian prime minister who coined the conga line comparison, put it this way: “Pretty much all the international leaders I have seen that have sucked up to Trump have been run over. The reality is if you suck up to bullies, whether it’s global affairs or in the playground, you just get more bullying.”
Trading partners may be able to mitigate the impact of these tariffs through negotiation, but that may only encourage this unorthodox president to demand ever more?
Ultimately the world will need a more reliable superpower than that.
In the hands of such a president, America cannot be counted on.
When it comes to security, stability and prosperity, allies will need to fend for themselves.
And they will need new friends. If Washington can’t be relied on, Beijing beckons.
America First will, more and more, mean America on its own.
Actors, directors and celebrity friends have paid tribute to Val Kilmer, after he died aged 65.
The California-born star of Top Gun, Batman and Heat died of pneumonia on Tuesday night in Los Angeles, his daughter Mercedes told the Associated Press.
She said Kilmer was diagnosed with throat cancer in 2014 but later recovered.
Tributes flooded in after reports broke of the actor’s death, with No Country For Old Men star Josh Brolin among the first to share their memories.
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2:49
Watch: Val Kilmer in his most iconic roles
He wrote on Instagram: “See ya, pal. I’m going to miss you. You were a smart, challenging, brave, uber-creative firecracker. There’s not a lot left of those.
“I hope to see you up there in the heavens when I eventually get there. Until then, amazing memories, lovely thoughts.”
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Kyle Maclachlan, who co-starred with Kilmer in the 1991 biopic The Doors, wrote on social media: “You’ll always be my Jim. See you on the other side my friend.”
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Michael Mann, who directed Kilmer in 1995’s Heat, also paid tribute in a statement, saying: “I always marvelled at the range, the brilliant variability within the powerful current of Val’s possessing and expressing character.
“After so many years of Val battling disease and maintaining his spirit, this is tremendously sad news.”
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Heat co-star Danny Trejo also called Kilmer “a great actor, a wonderful person, and a dear friend of mine” on Instagram.
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Cher, who once dated the actor, said on X that “U Were Funny, crazy, pain in the ass, GREAT FRIEND… BRILLIANT as Mark Twain, BRAVE here during ur sickness”.
Lifelong friend and director of Twixt, Francis Ford Coppola said: “Val Kilmer was the most talented actor when in his High School, and that talent only grew greater throughout his life.
“He was a wonderful person to work with and a joy to know – I will always remember him.”
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The Top Gun account on X also said it was remembering Kilmer, who starred as Iceman in both the 1986 original and 2022 sequel, and “whose indelible cinematic mark spanned genres and generations”.
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