Cervical cancer rates are almost 90% lower in women vaccinated against HPV, a new study has found.
Women offered the vaccine between the ages of 12 and 13 were found to have cancer rates 87% lower than in previous generations, according to a study published in The Lancet.
Researchers also found a reduction of 62% in women vaccinated between ages 14 and 16.
Image: England began rolling out its HPV vaccination programme in 2008
The first generation of women, who were offered “catch-up” jabs aged between 16 and 18, were found to have a 34% reduction in cervical cancer rates.
Professor Peter Sasieni, from King’s College London and one of the authors of the paper, told Sky News some of the results were “almost too good to be true”.
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“Everything is on target to be preventing essentially all cancers from HPV 16 and 18 in vaccinated women,” he said.
He said there was also “some cross-protection” for other cancers caused by the human papillomavirus and “some protection, although much less, to women of the same age who are not actually vaccinated”.
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He continued: “There is a lot of vaccine hesitancy going on these days.
“People who are opposed to these vaccines can no longer say this vaccine doesn’t prevent cancer because this makes it absolutely clear it is having a dramatic effect on cervical cancer incidents.”
“We need to think about the impact that will have,” he said.
“People don’t come in because they are revising, or they only come in for exams. So to get the same uptake of the vaccine will be challenging – as I am sure it has been challenging the last year and a half because of COVID.”
HPV vaccination has been introduced in 100 countries as part of efforts by the World Health Organisation (WHO) to eliminate cervical cancer.
It is a common sexually transmitted infection, with some types being linked to cervical cancer in women and head and neck cancer in men.
The English HPV vaccination programme was introduced in 2008, with vaccines given to women aged between 12 and 13 and “catch-up” jabs offered to older age groups up to the age of 18.
England initially used a bivalent vaccine, which protects against the two most common types of HPV, responsible for approximately 70% to 80% of all cervical cancers. Since September 2012, the quadrivalent vaccine Gardasil has been used instead.
The study looked at the population-based cancer registry data between January 2006 and June 2019 for seven cohorts of women, aged between 20 and 64.
Image: Women offered the vaccine between the ages of 12 and 13 have an 87% reduction in cancer rates
During that time frame, 28,000 diagnoses of cervical cancer and 300,000 diagnoses of non-invasive cervical carcinoma (CIN3) in total were recorded in England.
In the three vaccinated cohorts, there were just 638 cases of cervical cancers and 18,662 cases of CIN3 compared to the non-vaccinated population.
Prof Sasieni said cases in young women were “very traumatic on everyone”.
“When talking to colleagues who treat women, they always remember the young ones and sometimes it is very aggressive and they can’t help that much,” he said.
One of the benefits of such an effective vaccine, he said, could mean women require less cervical screening, adding: “It doesn’t make sense to say you need to continue screening in the same way.”
Image: In the three vaccinated cohorts, there were around 450 fewer cases of cervical cancers
But he said until the policy was changed, “the last thing we want is for women to think, I have been vaccinated so I don’t need to attend my screening – because that could have really serious consequences”.
The authors of the study did acknowledge some limitations – principally that cervical cancer diagnosis is rare in young women. Because the vaccinated populations are still young, the authors also stressed this means that it is still too early to assess the full impact of HPV immunisation on cervical cancer rates.
The freed suspect in the Madeleine McCann case has spoken publicly for the first time since his release – but refused to discuss the mystery of the missing British toddler.
In an exclusive Sky News interview, he hit out after trying to confront the prosecutor who has accused him of abducting and murdering Madeleine.
Christian B, who cannot be fully identified under German privacy laws, travelled more than a hundred miles from a secret address to prosecutor Hans Christian Wolters’ office, but was stopped from going in.
The suspect said: “I want them to stop this witch-hunt against me and give me back my life.
“I’m not feeling free. I have this ankle tag and I’m followed around by police 24/7, so I’m not feeling free.”
Image: Christian B tried to speak to lawyer and prosecutor Hans Christian Wolters
Mr Wolters has stated publicly that he has evidence, which he has not revealed, to show Christian B abducted and killed Madeleine, who vanished from her bed during a Portuguese holiday in 2007.
But he said he doesn’t have enough evidence to arrest or charge him.
The suspect, who was released from a rape sentence two weeks ago, said: “The prosecutor refused to meet me, but I told his representative I wanted his help to get my life back.
“I’m being hounded by the media and it’s his fault. I want him to take responsibility.
“I was told there was nothing they could do to help. They said I had been convicted and released and I wasn’t their responsibility.”
As he spoke, the electronic tag that has monitored his movements since his release was clearly visible above his right ankle. He has also had to surrender his passport and report regularly to probation staff.
Image: Madeleine vanished during a Portuguese holiday in 2007. File pic: PA
The suspect has not been arrested, charged or even questioned by German authorities about the Madeleine case. He’s also refused to talk to Scotland Yard and Portuguese police, who are also involved in the investigation.
Asked directly if he had abducted and killed Madeleine McCann, he said: “My defence lawyers have told me to say nothing on this topic and unfortunately I have to abide by that.”
Christian B, 49, was driven from jail by his lawyer, Friedrich Fulscher, on 17 September and, since then, has lived in local authority accommodation in the town of Neumunster, north of Hamburg.
Journalists quickly tracked him down and exposed his new address, prompting anger in the community from people worried about his convictions for child sex crimes.
Image: Pic: Markus Hibbeler/Bild
Image: Christian B pictured on the day of his release earlier this month. Pic: Markus Hibbeler/Bild
Local councillor Karin Mundt, of the hard-right populist movement Heimat Neumunster (Homeland Neumunster), took to Facebook to warn locals to be vigilant, not go out alone, and make sure that their children and elderly were safe.
She also called for a public protest under the slogan ‘Christian B out of Neumunster – tougher measures against child abusers and rapists to protect all citizens!’
Germany operates draconian privacy laws, whereby even the media must get the consent of someone they photograph, or disguise their features.
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Madeleine McCann suspect released from jail
Yet the group even decided to publish photos of Christian B, arguing that the danger he presents meant he was a public person of interest, and that they had to make sure that elderly people were able to recognise him.
Two separate chat groups were set up, one dedicated to campaigning for Christian B to be booted out of Neumunster, the other to discuss alleged sightings of him.
‘Out for a steak’
Some claimed that Christian B had turned up near schools and that the police were called round, though other people said they worked at these schools, and that no police had been there.
A woman at Domino’s pizza claimed he had turned up in a false beard, yet just days later her colleague said she had seen the pictures and she was unsure that it was Christian B.
Throughout all this, a source close to Christian B’s defence claimed he had not been out at all apart from to sort out his phone, and also once for a steak.
On Wednesday, one chat even discussed gathering at the town hall in the evening, and police vans then turned up to try to prevent this.
The language of the chat became ever bolder – with people openly posting addresses they were convinced he was living at – and, at one point, all people with English-sounding surnames were ejected from the group as people suspected they were journalists.
Image: Another search near Praia De Luz, Portugal, drew a blank in June. Pic: PA
Police moved Christian B out of Neumunster, and reports say he’s since been spotted at a hotel in an unnamed town.
In a recent interview with Germany’s Stern magazine, Christian B’s main lawyer, Dr Fulscher, said: “The Braunschweig public prosecutor’s office has fuelled this media campaign of prejudgement.
“It has told the public that it is certain it has the right person. Without presenting sufficient evidence or even allowing my client to inspect the files.
“I find this highly questionable from a constitutional point of view. In my opinion, the Braunschweig public prosecutor’s office has made rehabilitation impossible.”
Prosecutor Mr Wolters told Sky News he’d been tipped off about the suspect’s visit to his office in Braunschweig, near Hanover, and refused to speak to him.
Christian B denies any involvement in Madeleine’s disappearance.
Andy Burnham would beat Sir Keir Starmer among Labour members by two to one if there were a leadership contest today, an exclusive poll for Sky News reveals.
A poll of 704 Labour members taken a week ago by YouGov found that 62% would back Mr Burnham, and 29% would back Sir Keir. Just 9% don’t know or would not vote.
Mr Burnham has claimed some Labour MPs are asking him to stand for the leadership, and has used this conference to set out his stall, though there is not an obvious route for him to return to Parliament.
If returned to the Commons, he would have to resign as Manchester Metro Mayor, with a Reform UK replacement in prime position to win the mayoralty.
The poll reveals that around a third of Labour members polled no longer think that Sir Keir is a good prime minister, and would rather he did not fight the next election. Some 33% say he is doing a bad job, compared with 63% who think he is doing a good job.
Even more – 37% – say Sir Keir should not take the party into the next election, while 53% say he should and 10% don’t know. People are more likely to say that Labour is doing a good job than Sir Keir.
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The mayor of Greater Manchester gives no comment to Sky News as he walks to a fringe meeting at the Labour conference in Liverpool.
Mr Burnham is the favourite to succeed him by a long distance – the top pick of 54% of members.
Next is Angela Rayner, the now-sacked deputy leader (10%), then Health Secretary Wes Streeting on 7%. Ex-leader, now energy secretary, Ed Miliband and foreign secretary Yvette Cooper are on 6%, and new home secretary Shabana Mahmood is on 2%.
Mr Burnham comfortably beats all in a final round of voting, according to the poll.
In the event that Mr Burnham was unable to stand, YouGov polled a number of head-to-head races. Wes Streeting beats Shabana Mahmood and Ed Miliband, but would lose to Angela Rayner and Yvette Cooper. Ms Mahmood would lose to Mr Miliband and Ms Cooper. And Ms Cooper would beat Mr Miliband.
The poll also examined attitudes to the deputy leadership contest.
The poll found 35% would back Lucy Powell and 28% would back Bridget Phillipson, while 30% do not know and 5% will not vote. Excluding ‘don’t know’, this suggests Ms Powell is ahead of Ms Phillipson with 56% to 44% – a closer margin than some other pollsters.
Broadly, members who back Ms Powell are less likely to support Sir Keir.
The poll makes tough reading for Angela Rayner – 60% said she was right to resign, against 34% who said it was the wrong decision.
A woman has pleaded guilty to money laundering offences over the UK’s biggest-ever cryptocurrency seizure of Bitcoin, currently worth more than £5bn.
Chinese national Yadi Zhang, 47, who is also known as Zhimin Qian, was arrested in April last year after spending years on the run.
She first arrived in the UK on a false St Kitts and Nevis passport in September 2017 after allegedly carrying out a £5bn investment scam in China involving 130,000 investors in fraudulent wealth schemes between 2014 and 2017.
Police first raided her £5m six-bedroom rented house near Hampstead Heath, in north London, on 31 October 2018.
Image: Zhang rented a £5m house in Hampstead. Pic: CPS
But it was another two and a half years before investigators discovered more than 61,000 Bitcoin in digital wallets – one of the biggest ever cryptocurrency seizures in the world.
The cryptocurrency was worth £1.4bn at the time but its value has now risen to more than £5bn and the fortune is at the centre of an intense battle between the UK government and Chinese investors over who gets to keep it.
Image: Bundles of cash found in a police search. Pic: CPS
The seized assets have reportedly been earmarked by Chancellor Rachel Reeves to help plug the hole in the public finances.
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Zhang was due to face trial at Southwark Crown Court but has pleaded guilty to charges of possessing criminal property and transferring criminal property on or before 23 April 2024.
She appeared in the dock wearing glasses and a beige cardigan over an animal print blouse, nodding to confirm her identity before entering her pleas with the help of a mandarin interpreter.
Judge Sally-Ann Hales remanded Zhang in custody ahead of sentencing at a later date.
Prosecutor Gillian Jones KC said she would not apply to launch confiscation proceedings because of the ongoing proceedings in the High Court.
Image: Jian Wen. Pic: CPS
Jian Wen, 43, was last year jailed for six years and eight months after being found guilty of one count of money laundering between October 2017 and January 2022 relating to 150 Bitcoin, now worth around £12.5m.
Her trial heard Wen was not involved in the alleged fraud but was said to have acted as a “front person” to help disguise the source of the money, some of which had been used to buy cryptocurrency and smuggled out of China on laptops.
Will Lyne, the Metropolitan Police’s head of economic and cybercrime command, said Zhang’s guilty pleas marked the culmination of “years of dedicated investigation”.
“This is one of the largest money laundering cases in UK history and among the highest-value cryptocurrency cases globally,” he said.
Zhang’s solicitor, Roger Sahota of Berkeley Square Solicitors, said: “By pleading guilty today, Ms Zhang hopes to bring some comfort to investors who have waited since 2017 for compensation, and to reassure them that the significant rise in cryptocurrency values means there are more than sufficient funds available to repay their losses.”