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The chief executive of AstraZeneca (AZ) has told Sky News that the company’s decision to begin seeking a modest profit from its COVID vaccine is unlikely to kick in until next year.

Pascal Soriot said this was because it still had many doses of the vaccine to supply that it had promised to do so at cost.

AZ announced earlier this month that it would be seeking to achieve a modest profit in future from the vaccine In order to fund its new anti-viral COVID treatment.

But Mr Soriot stressed that, while some countries would be charged above cost for the vaccine, many more would not.

AstraZeneca. Pic: AP
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The Oxford-AstraZeneca vaccine has been sold at cost since it first became available Pic: AP

He said: “You have to remember that the orders we are taking today will be delivered next year. We still have a lot of orders at no profit to deliver. So they will be delivered next year.

“So you have got to think of the infection as if you were already in next year. And so essentially most of the world at that point will be in a different phase. And we will be more in a regional epidemic or regional pandemic than a global pandemic.

“But you know, we will of course adapt to every circumstance and countries that have low purchasing power we will be supplied at no profit or very low price and others will be a bit more.”

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Mr Soriot insisted that he had no regrets that AZ had provided the vaccine at cost even though some of its competitors, such as Pfizer and Moderna, have supercharged their profits through charges for their COVID vaccines.

He went on: “We always knew that some vaccines would be sold at a profit and we made the decision from day one that we would partner with Oxford and deliver this vaccine around the world at no profit so everybody could access it much as possible.

Vials of COVID vaccines made by AstraZeneca, Pfizer, Johnson and Johnson, and Sputnik V
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Vials of COVID vaccines made by AstraZeneca, Pfizer, Johnson and Johnson, and Sputnik V

“And again, we’ve delivered more than 2 billion doses, 30% of global supply so far, so it really has worked quite well actually. So we always knew that it was what we were going to do. So there is no surprise, so there can’t be any regret – it was our plan all along.”

He was speaking as AZ, the largest company in the FTSE 100, formally unveils The Discovery Centre, its new £1bn research and development facility in Cambridge, which will be home to some 2,200 scientists.

The centre, to be opened by the Prince of Wales today, represents the biggest single investment ever made by AZ.

It has been specifically sited in Cambridge to be at the heart of the city’s life sciences cluster, within close proximity to the Royal Papworth and Addenbrookes hospitals, Cancer Research UK and the University of Cambridge’s school of clinical medicine.

The site is referred to in scientific circles as the ‘Nobel factory’ as it has created more Nobel Prize winners than anywhere else in the world.

Mr Soriot said AZ spent around $7bn (£5.3bn) on research and development annually – of which “a large proportion”, close to one third, is deployed in the UK.

He added: “it’s a very substantial investment we make each year.”

The opening comes at a hugely busy time for AZ which, earlier this year, completed the $39bn takeover of the rare diseases specialist Alexion.

That took the company, traditionally better known in the industry for its treatments for cancers, heart and respiratory conditions, into a fourth therapy area – and now it has decided, based on the success of its COVID vaccine roll out, to expand into a fifth, vaccines, as well.

However, asked whether AZ was trying to do too much at once, Mr Soriot insisted this was not the case.

He added: “We have great strengths in oncology and we believe we can be one of the three great companies in the world in oncology and maybe even better than that by 2025.

“We continue to do very well in cardiovascular and bio pharmaceuticals overall and now we have rare diseases and vaccines.

“What we call the vaccine and immunotherapy unit is really looking at is managing this portfolio of products to treat or vaccinate people with viral diseases.

“We want to maximise the value of these assets and manage them better.

“Now whether we invest in the long run in this field remains to be seen, but there’s a lot of synergies across this portfolio of products.”

Mr Soriot pointed out that AZ had just achieved its first quarter during which it had notched up $10bn worth of sales.

It is a significant milestone because, when Mr Soriot oversaw AZ’s successful defence against an unwanted takeover approach from Pfizer in 2014, he promised investors that AZ would be delivering annual sales of $40bn a year by 2023.

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Rishi Sunak pledges to remove benefits for people not taking jobs after 12 months

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Rishi Sunak pledges to remove benefits for people not taking jobs after 12 months

People who are fit to work but do not accept job offers will have their benefits taken away after 12 months, the prime minister has pledged.

Outlining his plans to reform the welfare system if the Conservatives win the next general election, Rishi Sunak said “unemployment support should be a safety net, never a choice” as he promised to “make sure that hard work is always rewarded”.

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Mr Sunak said his government would be “more ambitious about helping people back to work and more honest about the risk of over-medicalising the everyday challenges and worries of life” by introducing a raft of measures in the next parliament. They include:

• Removing benefits after 12 months for those deemed fit for work but who do not comply with conditions set by their work coach – such as accepting a job offer

• Tightening the work capability assessment so those with less severe conditions will be expected to seek employment

• A review of the fit note system to focus on what someone can do, to be carried out by independent assessors rather than GPs

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• Changes to the rules so someone working less than half of a full-time week will have to look for more work

• A consultation on PIP to look at eligibility changes and targeted support – such as offering talking therapies instead of cash payments

• The introduction of a new fraud bill to treat benefit fraud like tax fraud, with new powers to make seizures and arrests.

He insisted the changes were not about making the benefits system “less generous”, adding: “I’m not prepared to balance the books on the backs of the most vulnerable.

“Instead, the critical questions are about eligibility, about who should be entitled to support and what kind of supports best matches their needs.”

But Labour said it was the Tories’ handling of the NHS that had left people “locked out” of work, and a disabled charity called the measures “dangerous”.

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The latest data from the Office for National Statistics (ONS) shows 9.4 million people aged between 16 and 64 were “economically inactive”, with over 2.8 million citing long-term sickness as the reason.

Mr Sunak said 850,000 of them had been signed off since the COVID pandemic and half of those on long-term sickness said they had depression, with the biggest growth area being young people.

He also claimed the total being spent on benefits for people of working age with a disability or health condition had increased by almost two-thirds since the pandemic to £69bn – more than the entire budget for schools or policing.

“I will never dismiss or downplay the illnesses people have,” said the prime minister. “Anyone who has suffered mental ill health or had family and friends who have know these conditions are real and they matter.

“But just as it would be wrong to dismiss this growing trend, so it would be wrong to merely sit back and accept it because it’s too hard, too controversial, or for fear of causing offence.”

Rishi Sunak during his speech welfare reform.
Pic: PA
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Rishi Sunak during his speech on welfare reform. Pic: PA

The prime minister said he knew critics would accuse him of “lacking compassion”, but he insisted “the exact opposite is true”, adding: “There is nothing compassionate about leaving a generation of young people to sit in the dark before a flickering screen, watching as their dreams slip further from reach every passing day.

“And there is nothing fair about expecting taxpayers to support those who could work but choose not to.

“It doesn’t have to be like this. We can change. We must change.”

But Labour said the “root cause of economic activity” was down to the Tories’ failure on the health service, with record NHS waiting lists hitting people’s ability to get back in the workplace.

Acting shadow work and pensions secretary Alison McGovern said: “After 14 years of Tory misery, Rishi Sunak has set out his failed government’s appalling record for Britain: a record number of people locked out of work due to long-term sickness and an unsustainable spiralling benefits bill.

“Rather than a proper plan to get Britain working, all we heard today were sweeping questions and reheated proposals without any concrete answers.”

Liberal Democrat leader Sir Ed Davey called it “a desperate speech from a prime minister mired in sleaze and scandal”, adding: “Rishi Sunak is attempting to blame the British people for his own government’s failures on the economy and the NHS and it simply won’t wash.”

Meanwhile, disability charity Scope said the measures were a “full-on assault on disabled people”, adding they were “dangerous and risk leaving disabled people destitute”.

James Taylor, director of strategy at the charity, said calls were already “pouring in” to their helpline with people concerned about the impact on them, adding: “Sanctions and ending claims will only heap more misery on people at the sharp end of our cost of living crisis.”

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Tesla recalls thousands of Cybertrucks over jammed accelerator issue

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Tesla recalls thousands of Cybertrucks over jammed accelerator issue

Tesla has recalled more than 3,800 of its Cybertruck models following complaints that the accelerator pedal is at risk of getting stuck, US regulators have announced.

The National Highway Traffic Safety Administration (NHTSA) had contacted the carmaker, founded and run by Elon Musk, about the issue earlier in the week.

That was after a video came to light, on the billionaire entrepreneur’s X platform and TikTok, showing how a rubber cover attached to the accelerator could come loose, pinning the pedal down.

It has since been watched millions of times on both platforms.

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The interior of the Cybertruck. Pic: Tesla
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The interior of a Cybertruck. Pic: Tesla

Tesla was widely reported to have temporarily halted sales and deliveries after being contacted by the NHTSA.

The regulator said a total of 3,878 Cybertrucks were affected by the recall.

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Tesla started deliveries of its Cybertruck electric pickup truck late last year, after a two-year delay due to production problems and battery-supply constraints.

The EV maker will replace or repair the accelerator pedal assembly at no charge and owners will be notified through letters mailed to them in June, the NHTSA said.

Cybertruck owner Jose Martinez told Sky’s US partner network NBC News how he was driving his new Cybertruck of just six days on his local drag strip in southern California when the car started accelerating on its own.

He said: “The moment I let go of the brake, it would lurch forward at full throttle again.

“I had space where I could figure out what was going on. It wasn’t a situation where there were cars in front of me or a building or a tree.”

Read more from Sky News:
Retail sales show zero growth
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He later filmed the video which went viral, to demonstrate the issue and said he had performed a temporary fix by simply removing the rubber cover on the pedal.

“Other than this, it’s a pretty solidly built car,” Martinez continued.

“I know saying ‘other than this’ makes it sound like it’s not major, and it is.”

“Because it is such a massive car, and it’s got such a great amount of power, I do feel like things in regard to safety definitely need to be a priority in getting it addressed and fixed,” he added.

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Retail sales show zero growth despite ‘fresh two-year high’ for consumer confidence

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Retail sales show zero growth despite 'fresh two-year high' for consumer confidence

There was a worse than expected performance for retail sales last month, defying predictions of a consumer-led pick up from recession for the UK economy.

The Office for National Statistics (ONS) reported sales volumes were flat in March, following an upwardly revised figure of 0.1% for the previous month.

It said sales at non-food stores helped offset declines at supermarkets.

Sales of fuel rose by 3.2%.

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ONS senior statistician Heather Bovill said of the overall picture: “Retail sales registered no growth in March.

“Hardware stores, furniture shops, petrol stations and clothing stores all reported a rise in sales.

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“However, these gains were offset by falling food sales and in department stores where retailers say higher prices hit trading.

“Looking at the longer-term picture, across the latest three months retail sales increased after a poor Christmas.”

While the performance will not damage the expected exit from recession during the first quarter of the year, it suggests that consumers are still carefully managing their spending.

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‘Economy has turned a corner’

While the cost of living crisis – exacerbated by the Bank of England’s interest rate rises to push inflation down – has severely damaged budgets, wage growth has been rising at a faster pace than prices since last summer.

Separate ONS data this week has shown the annual rate of inflation at 3.2% – with wages growing at a rate of 6% when the effects of bonuses are stripped out.

Economists widely believe consumer spending power will win through as the year progresses, despite borrowing costs remaining at elevated levels.

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Inflation slows to 3.2%


A measure of consumer confidence released on Friday showed confidence had increased for a sixth consecutive quarter to its highest level since the summer of 2021.

Deloitte’s measure showed an increase of 6.5 percentage points on this time last year.

Its survey cited an improvement in personal finances as inflation eased.

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Post Office had ‘bunker mentality’ towards press

The company’s consumer insight lead Celine Fenech said of its findings: “It is encouraging to see that consumers are feeling more confident in their personal finances – particularly younger consumers.

“Many consumers are paying less for essentials such as utility bills… however, spending on non-essential goods and services dropped this quarter, meaning that improving confidence is not yet translating to a significant boost to spending, and cautious optimism is required.”

She added: “Consumer confidence at its highest level in two-and-a-half years combined with the weather hopefully improving, should signal a brighter outlook for the consumer sector.”

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