Official figures showed more than 30,000 new coronavirus cases in Germany in the last 24-hour period, an increase of about 50% compared to a week ago.
Hospitals have warned that intensive care capacities are nearly exhausted, with some patients being transferred to clinics some distance away.
Mr Spahn urged Germans to get the jab, including booster shots if their first round of inoculation occurred more than six months ago, to reduce the risk of serious illness.
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“By the end of this winter pretty much everyone in Germany will have been vaccinated, recovered or died,” he said.
He acknowledged that some had described this view as cynical.
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“But it’s true. With the highly contagious Delta variant, this is very, very likely and that’s why we are recommending vaccination so urgently.”
Mr Spahn said around 50 million doses of the Moderna and BioNtech/Pfizer vaccines would be made available for the rest of the year to allow people to get first, second or third doses.
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COVID cases in Germany hit record high
To achieve this, Germany was holding back tens of millions of doses, which were meant for poor countries.
About 68% of Germany’s population has been fully vaccinated but the government has said it wants to push that rate above 75% to curb the spread of the virus, but a sizeable minority in the population has resisted calls to take the vaccine.
Karl Lauterbach, a prominent politician with the centre-left Social Democrats, called for a “radical” application of rules requiring people to present vaccination or recovery certificates to access some shops and public places.
“A general vaccine mandate (shouldn’t be) taboo either,” he wrote on Twitter.
Bavaria’s conservative governor, Markus Soeder, said on Monday that he also favoured mandatory vaccines for all.
But a spokesman for outgoing German chancellor Angela Merkel made clear that her government had no plans to tackle the controversial issue of vaccine mandates.
New pictures show the moment of impact as an Israeli missile hit a Beirut apartment block and exploded.
The block was one of five buildings destroyed by airstrikes on Friday alone.
Israel launched airstrikes in the southern suburbs of Beirut in a fourth consecutive day of intense attacks.
There were no immediate reports of casualties.
An Associated Press photographer captured a sequence of images showing an Israeli bomb approaching and hitting a multi-storey apartment building in Beirut’s Tayouneh area.
Richard Weir, a senior crisis, conflict and arms researcher at Human Rights Watch, reviewed the close-up photos to determine what type of weapon was used.
“The bomb and components visible in the photographs, including the strake, wire harness cover, and tail fin section, are consistent with a Mk-84 series 2,000-pound class general purpose bomb equipped with Boeing’s joint directed attack munition tail kit,” he told AP.
Deadly strikes as bombardment stepped up
Israel stepped up its bombardment this week – an escalation that has coincided with signs of movement in US-led diplomacy towards a ceasefire.
The Israeli military said its fighter jets attacked munitions warehouses, a headquarters and other Hezbollah infrastructure. It issued a warning on social media identifying buildings ahead of the strikes.
Meanwhile, an Israeli airstrike killed five members of the same family in a home in Ain Qana in the southern province of Nabatiyeh, Lebanon’s state media said.
The report said a mother, father and their three children were killed but didn’t provide their ages.
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Three other Israeli strikes killed six people and wounded 32 in different parts of Tyre province on Friday, also in south Lebanon, the report said.
Video footage also showed a building being struck and turning into a cloud of rubble and debris that billowed into Horsh Beirut, the city’s main park.
More than 3,200 people have been killed in Lebanon during 13 months of fighting between Israel and Hezbollah – most of them since mid-September.
About 27% of those killed were women and children, according to Lebanon’s health ministry.
Israel dramatically escalated its bombardment of Lebanon from September, vowing to cripple Hezbollah and end its barrages in Israel.
Friday’s strikes come as Lebanon’s caretaker prime minister has asked Iran to help secure a ceasefire in the war between Israel and Hezbollah.
The prime minister appeared to urge Ali Larijani, a top adviser to Iran’s supreme leader, Ali Khamenei, to convince the militant group to agree to a deal that could require it to pull back from the Israel-Lebanon border.
Iran is a main backer of Hezbollah and for decades has been funding and arming the Lebanese militant group.
On Thursday, Eli Cohen, Israel’s energy minister and a member of its security cabinet, said that prospects for a ceasefire with Lebanon were the most promising since the conflict began.
The Washington Post reported Israel’s Prime Minister Benjamin Netanyahu was rushing to advance a Lebanon ceasefire to deliver an early foreign policy win to his ally, US President-elect Donald Trump.
“Super high-IQ revolutionaries” who are willing to work 80+ hours a week are being urged to join Elon Musk’s new cost-cutting department in Donald Trump’s incoming US government.
The X and Tesla owner will co-lead the Department Of Government Efficiency (DOGE) with former Republican presidential candidate Vivek Ramaswamy.
In a reply to an interested party, Mr Musk suggested the lucky applicants would be working for free.
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“Indeed, this will be tedious work, make lost of enemies & compensation is zero,” the world’s richest man wrote.
“What a great deal!”
When announcing the new department, President-elect Donald Trump said Mr Musk and Mr Ramaswamy “will pave the way for my administration to dismantle government bureaucracy, slash excess regulations, cut wasteful expenditures, and restructure federal agencies”.
Mr Musk has previously made clear his desire to see cuts to “government waste” and in a post on his X platform suggested he could axe as many as three-quarters of the more than 400 federal departments in the US, writing: “99 is enough.”
At least 10 people have been killed after a fire broke out at a retirement home in northern Spain in the early hours of this morning, officials have said.
A further two people were seriously injured in the blaze at the residence in the town of Villafranca de Ebro in Zaragoza, according to the Spanish news website Diario Sur.
They remain in a critical condition, while several others received treatment for smoke inhalation.
Firefighters were alerted to the blaze at the residence – the Jardines de Villafranca – at 5am (4am UK time) on Friday.
Those who were killed in the fire died from smoke inhalation, Spanish newspaper Heraldo reported.