Liz Truss has sacked trade minister Conor Burns from her government “with immediate effect” following an allegation of serious misconduct.
The Tory MP for Bournemouth West has also had the whip suspended while the complaint is investigated.
A No 10 spokesman said: “Following a complaint of serious misconduct, the prime minister has asked Conor Burns MP to leave the government with immediate effect.
“The prime minister took direct action on being informed of this allegation and is clear that all ministers should maintain the high standards of behaviour – as the public rightly expects.”
A whips office spokesman said: “We have suspended the whip pending investigation into allegations of inappropriate behaviour earlier this week.
“We take all such allegations extremely seriously. The prime minister has been clear that the highest standards in public life must be upheld.”
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It comes after the annual Conservative Party conference took place in Birmingham from last Sunday to Wednesday.
Mr Burns, 50, has said he will co-operate fully with the probe and “looks forward to clearing his name”.
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In a statement on Twitter, he said he was not given any details about the complaint or asked to provide any information.
He said: “I hope the party will be as quick to conduct their enquiry as they were to rush to judgement.”
Mr Burns has been an MP since 2010 and held a number of ministerial positions under Boris Johnson, to whom he was fiercely loyal.
Image: Conor Burns has been an MP since 2010
Earlier this year, he infamously claimed the former PM was “ambushed with cake” in defence of claims of a lockdown party in Downing Street.
Government minister Victoria Prentis said the allegations were “obviously concerning”, but she had been assured the matter was being taken “very seriously”.
“I think all I can say is that the prime minister has taken decisive action, and we’ll make sure that this is properly investigated,” she told Times Radio.
But Angela Rayner, deputy leader of the Labour Party, said the allegation “raises serious questions” about the prime minister’s judgement in refusing to appoint an independent ethics adviser.
The development is the latest in a series of scandals to rock the Conservative Party.
In July, former deputy chief whip Chris Pincher resigned from his post after he was accused of groping two men in a private members’ club – with the fallout ultimately leading to Boris Johnson’s downfall.
At least 20 people have been killed and dozens more injured after an Israeli airstrike targeting a school in Gaza, health authorities have said.
Reuters news agency reported the number of dead, citing medics, with the school in the Daraj neighbourhood having been used to shelter displaced people who had fled previous bombardments.
Medical and civil defence sources on the ground confirmed women and children were among the casualties, with several charred bodies arriving at al Shifa and al Ahli hospitals.
The scene inside the school has been described as horrific, with more victims feared trapped under the rubble.
This breaking news story is being updated and more details will be published shortly.
Donald Trump has threatened Russia with more sanctions after a series of deadly strikes across Ukraine, as he said of Vladimir Putin: “What the hell happened to him?”
Speaking to reporters at an airport in New Jersey ahead of a flight back to Washington, Mr Trump said: “I’m not happy with Putin. I don’t know what’s wrong with him.”
“He’s killing a lot of people,” he added. “I’m not happy about that.”
Mr Trump – who said he’s “always gotten along with” Mr Putin – told reporters he would consider more sanctions against Moscow.
“He’s sending rockets into cities and killing people, and I don’t like it at all,” he said.
Ukraine said the barrage of strikes overnight into Sunday was the biggest aerial attack of the war so far, with 367 drones and missiles fired by Russian forces.
It came despite Mr Trump repeatedly talking up the chances of a peace agreement. He even spoke to Mr Putin on the phone for two hours last week.
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Hundreds of drones fired at Ukraine
‘Shameful’ attacks
Volodymyr Zelenskyy has said Ukraine is ready to sign a ceasefire deal, and suggested Russia isn’t serious about signing one.
In a statement after the latest attacks on his country, he urged the US and other national leaders to increase the pressure on Mr Putin, saying silence “only encourages” him.
Mr Trump’s envoy for the country, Keith Kellogg, later demanded a ceasefire, describing the Russian attacks as “shameful”.
Three children were among those killed in the attacks, explosions shaking the cities of Kyiv, Odesa, and Mykolaiv.
Image: Ukrainian siblings Tamara, 12, Stanislav, eight, and Roman, 17, were killed in Russian airstrikes. Pic: X/@Mariana_Betsa
Before the onslaught, Russia said it had faced a Ukrainian drone attack on Sunday. It said around 100 were intercepted and destroyed near Moscow and in central and southern regions.
The violence has escalated despite Russia and Ukraine completing the exchange of 1,000 prisoners each over the past three days.
Donald Trump says he will delay the imposition of 50% tariffs on goods entering the United States from the European Union until July, as the two sides attempt to negotiate a trade deal.
It comes after the president of the European Commission, Ursula von der Leyen, said in a post on social media site X that she had spoken to Mr Trump and expressed that they needed until 9 July to “reach a good deal”.
But Mr Trump has now said that date has been put back to 9 July to allow more time for negotiations with the 27-member bloc, with the phone call appearing to smooth over tensions for now at least.
Speaking on Sunday before boarding Air Force One for Washington DC, Mr Trump told reporters that he had spoken to Ms Von der Leyen and she “wants to get down to serious negotiations” and she vowed to “rapidly get together and see if we can work something out”.
The US president, in comments on his Truth Social platform, had reignited fears last Friday of a trade war between the two powers when he said talks were “going nowhere” and the bloc was “very difficult to deal with”.
Mr Trump told the media in Morristown, New Jersey, on Sunday that Ms Von der Leyen “just called me… and she asked for an extension in the June 1st date. And she said she wants to get down to serious negotiation”.
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“We had a very nice call and I agreed to move it. I believe July 9th would be the date. That was the date she requested. She said we will rapidly get together and see if we can work something out,” the US president added.
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12 May: US and China reach agreement on tariffs
Much of his most incendiary rhetoric on trade has been directed at Brussels, though, even going as far as to claim the EU was created to rip the US off.
Responding to his 50% tariff threat, EU trade chief Maros Sefcovic said: “EU-US trade is unmatched and must be guided by mutual respect, not threats.