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close video COVID moving into an endemic setting: Moderna CEO Stephane Bancel

Moderna CEO Stephane Bancel discusses the end stages of the COVID pandemic, booster shots, the company’s outlook for 2023, RSV vaccines, the melanoma trials and mRNA technology.

Modena CEO Stephane Bancel said coronavirus is transitioning from a pandemic to an endemic.

"It's tough to look precisely because none of us managed a transition from a pandemic to an endemic before. But we really think now that we're moving into an endemic setting," he told FOX Business’ Maria Bartiromo in an exclusive interview that aired on "Mornings with Maria" Tuesday.

US EXTENDS AIR TRAVEL COVID-19 VACCINE MANDATE FOR INTERNATIONAL VISITORS

Bancel went on to say the omicron booster resulted in "very good" clinical data in terms of vaccine efficacy. 

"I think we are now getting ready for yet another update in the fall, and we are going to move most probably to annual boosters for people at high risk."

Moderna CEO said the COVID pandemic is moving into an endemic. (Photo by JOSEPH PREZIOSO/AFP via Getty Images / Getty Images)

In 2022, Moderna generated a whopping $18.4 billion, but now analysts are lowering estimates for 2023 to a mere $5 billion. Bancel said that the projected $5 billion is a "flaw" in terms of sales and that the company sees that as a bare "minimum."  

"But $5 billion, we see it as a flaw, meaning those are things where we already have contracts place like with Canada and the U.K. This $5 billion assumes no sales in the U.S. And of course, we are currently talking to pharmacies and hospital network and doctors to have the new boosters available in the fall of 23'. So, I think that this is what we see as a minimum, as a flaw in terms of sales," the CEO explained.  close video Moderna, Merck create skin cancer vaccine showing promising results with melanoma patients

Moderna CEO Stephane Bancel discusses the ‘very exciting’ advancements of a new skin cancer vaccine shown to reduce the chance of a melanoma relapse by 44%.

Maria Bartiromo asked the CEO how he plans to "fill in" the revenue gap. He promptly responded that Moderna's "pipeline" of drugs in development will enable the company to maintain economic success. 

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"Thanks to our pipeline. I mean, as you know, we have this amazing platform where I think for one of the first time, if not the first time in the history of biology, we can do drugs very quickly. And so if you look at Moderna today, we have 48 drugs in development. Just in Q1 2023, we're going to have Phase 3 data very soon on RSV. And as you know, RSV has been really, really about this for the winter season," Bancel concluded.

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Olney: Yankees must replace Gerrit Cole — but they’ll probably have to wait

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Olney: Yankees must replace Gerrit Cole -- but they'll probably have to wait

Gerrit Cole‘s season is over, now that he is headed for Tommy John surgery, and the New York Yankees will have to find a way to replicate the production of a Cy Young Award-winning pitcher, someone who is likely to one day make a speech on induction day in Cooperstown.

But this is not a case of a team being blindsided by an injury. Past injuries are the most predictive indicators for future injuries, and after Cole missed nearly the first three months of last season with nerve inflammation in his right elbow, the Yankees knew the chances of losing him were heightened. Their handling of his contract situation last fall was a strong indicator of the uncertainty around Cole.

The pitcher and his agent, Scott Boras, opted out of the last four years of his contract, while asking that the Yankees exercise a $36 million option for the 2029 season, effectively adding a fifth year to his four-year, $144 million deal. Owner Hal Steinbrenner and GM Brian Cashman declined to do so, firmly holding the line, and days later, Cole returned to the Yankees without any augmentation of his contract. While the Yankees hoped Cole’s elbow would remain functional, as Masahiro Tanaka’s elbow did following a diagnosis of a partially torn ligament in 2014, they weren’t willing to bet another $36 million on it.

But that doesn’t help them very much right now, when they have lost two starting pitchers to significant arm injuries: Before Cole went down, Luis Gil — the American League Rookie of the Year last season — suffered a lat strain this spring that will keep him sidelined for much of the 2025 season. Max Fried, signed to a $218 million contract over the winter to improve a good rotation, will now be the de facto ace, in front of right-handers Clarke Schmidt and left-hander Carlos Rodon. A month ago, there was a lot of speculation about whether Marcus Stroman would be traded, given his standing as the sixth starter behind a five-man rotation, and now Stroman is needed as the No. 4 starter.

Cashman’s habit is to be patient — to weigh internal solutions before diving into another free agent signing or trade. When Cole was sidelined last spring, the Yankees thought Will Warren might step into his spot in the rotation, and instead, Gil surprisingly emerged to fill in for Cole and was one of the league’s best starting pitchers in the first half.

This year, Warren is having a very good spring, having allowed just two hits and a run in eight innings of work, with two walks and 11 strikeouts. Warren, an eighth-round pick out of Southeast Louisiana in 2021, is the front-runner to move into the Yankees’ rotation.

Just as the Yankees continue to weigh market options for hitting help while Giancarlo Stanton is attempting to work his way back from elbow trouble, they will consider free agent possibilities such as veteran right-hander Kyle Gibson. The Yankees paid for insurance on Cole’s contract, and so they will recoup some portion of the salary they owe him; typically, that rate is about 75%. His contract still counts against their competitive balance tax total, but the insurance money will significantly offset the luxury tax they will have to pay for the addition of any replacement: The Yankees are taxed dollar for dollar, 100%, for any additional player salaries they take on. A new $5 million player costs the Yankees $10 million.

Eventually, their best alternatives, if needed, could be through the trade market, and maybe that turns out to be the Miami MarlinsSandy Alcantara, the 2022 NL Cy Young Award winner who is back after an elbow reconstruction. Under the terms of a deal he signed with the Marlins early in his career, Alcantara is making $17.3 million this year and $17.3 million next season, and there is a $21 million option in his deal for 2027.

The Marlins are not expected to contend this year and have been in a cost-cutting mode since Peter Bendix took over the team’s baseball operations after the 2023 season. Last year, the Marlins demonstrated a willingness to deal very early in the season, when they swapped batting champion Luis Arraez to the San Diego Padres in the first week of May.

But the price of a trade in April or May is usually set by the team dealing away a star, and the Yankees would have to pay a big price in prospects in the spring after a rough year for their farm system, which is generally regarded as thin by other teams and ranked No. 21 in Kiley McDaniel’s preseason system rankings. Additionally, the Yankees would presumably compete against other teams if and when the Marlins look to trade Alcantara, leaving them at the same disadvantage they faced when trying to pry Garrett Crochet away from the Chicago White Sox — before Chicago dealt him to the Boston Red Sox.

Over the course of the summer, Gil could return from the injured list, and other pitchers could emerge on the trade market as some teams drift out of contention. If the Toronto Blue Jays struggle in the first half, they could be a key source for all kinds of needs, including starting pitchers. Jose Berrios, Kevin Gausman, Chris Bassitt and Max Scherzer might all draw interest if Toronto ever looks to rebuild and, in the Yankees’ case, is willing to deal within the division.

One or more National League West teams could end up feeding the trade market. The Padres enter this season with high expectations after nearly knocking out the Los Angeles Dodgers last summer, but if San Diego drifts behind in the playoff race, it holds two of the best impending free agents, Dylan Cease and former Yankee Michael King. Similarly, the San Francisco Giants have veteran Robbie Ray, who is under contract for $25 million this year and next, and the Arizona DiamondbacksZac Gallen will become eligible for free agency in the fall.

Likewise, in the AL West, the Mariners have so far clung to their starting pitchers, like Luis Castillo, but that could change if Seattle sinks in the standings. The Astros demonstrated their willingness to be aggressive with players nearing free agency with their trade of outfielder Kyle Tucker, and if Houston hovers around .500, it could flip Framber Valdez into the market — with his years of postseason experience attractive to contenders.

The pitching market could be flush with options in a few months. And the Yankees might wait until then to make a move to cover for Cole’s absence.

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Yankees ace Cole will have Tommy John surgery

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Yankees ace Cole will have Tommy John surgery

New York Yankees right-hander Gerrit Cole will undergo Tommy John surgery, the team announced Monday, ending his 2025 season before it began and leaving the club staggering from another blow as it prepares to defend its American League pennant.

The decision to have the surgery, which will sideline Cole for the 2025 season and at least part of the 2026 season, was made after seeking a second opinion from Dr. Neal ElAttrache on Monday. Cole will undergo the procedure Tuesday at the Cedars-Sinai Kerlan-Jobe Institute in Los Angeles. In a statement, the club said that “further updates will occur post surgery.”

Cole started two games this spring, giving up seven runs across six innings. On Thursday, he gave up six runs on five hits, including two home runs, over 2⅔ innings to the Minnesota Twins. He said he felt an “alarming” amount of pain that night into Friday morning, prompting him to notify the team and undergo imaging tests, which revealed a torn ulnar collateral ligament.

Cole, 34, went through the same series of stressful events a year ago: Elbow pain in mid-March, tests and opinions from doctors. But the result was different. Cole was diagnosed with nerve irritation and edema and, instead of surgery, he rested and rehabbed. He made his season debut on June 19 and pitched through the World Series without a setback.

In a statement he posted on Instagram later Monday, Cole said the surgery was a “necessary next step for my career,” adding that he has “a lot left to give, and I’m fully committed to the work ahead. I’ll attack my rehab every day and support the 2025 Yankees each step of the way. I love this game, I love competing, and I can’t wait to be back on the mound — stronger than ever.”

The ace logged 124 innings over 22 starts between the regular season and playoffs, tossing at least six innings in three of his five postseason outings. He then opted to alter his offseason throwing program by starting it earlier to continue his positive momentum. He said he was “in a really good spot” compared to other years at the start of camp.

But less than a month later, his season has been declared over.

Cole’s injury is the second major blow to the Yankees’ starting rotation this spring after Luis Gil, the reigning AL Rookie of the Year, sustained a lat strain that was expected to sideline him for at least three months.

Without the two right-handers, Max Fried, Carlos Rodon and Clarke Schmidt will top the Yankees’ starting rotation. Marcus Stroman, who was notably not expected to make the Opening Day rotation, is projected to slide into the No. 4 spot with Will Warren, a rookie who made his debut last season, and Carlos Carrasco, a soon-to-be-38-year-old veteran in camp as a non-roster invite, as the leading internal candidates to round out the quintet.

Other options in camp include right-hander Allan Winans, who has eight career starts on his résumé, and left-hander Brent Headrick, a starter in the minors who has never started a game in the majors.

The Yankees could also opt to sign a free agent — veterans Kyle Gibson and Lance Lynn are among those available — or swing a trade for an established starter.

Cole, a six-time All-Star, won the 2023 AL Cy Young Award and was the runner-up two other seasons. He has tallied at least 200 innings in six of his 10 full seasons (not including last year and the COVID-shortened 2020 season). He is as close to an old-school frontline workhorse in his prime that exists in baseball. It’s why the Yankees chose to sign Cole, a lifelong Yankees fan, to a nine-year, $324 million deal with a no-trade clause in December 2019 — the largest contract given to a pitcher at the time.

The agreement included a player opt-out after last season that the Yankees could’ve voided by attaching another year and $36 million to the four years and $144 million remaining on his contract. Cole exercised the opt out, but he never became a free agent and didn’t receive the extra year. Instead, the two sides agreed to continue as if Cole didn’t opt out two days later, keeping him under contract through the 2028 season at $36 million per year.

The Yankees have insurance on Cole’s contract, which will allow them to recoup some money for the time he’s out.

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Source: Dodgers, Roberts agree on 4-year deal

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Source: Dodgers, Roberts agree on 4-year deal

GLENDALE, Ariz. — Dave Roberts and the Los Angeles Dodgers are in agreement on a four-year extension that will set a record for average annual value on a manager’s contract, a source told ESPN on Monday.

The new deal, which runs from 2026 to 2029, will pay Roberts $32.4 million, carrying an $8.1 million average annual value that will narrowly edge out the yearly rate on Craig Counsell’s five-year, $40 million contract with the Chicago Cubs. Roberts, 52, will manage the 2025 season under his current contract, which was entering its final year.

A new deal was considered a foregone conclusion after the Dodgers secured their second championship in five years last fall. Serious negotiations began sometime around February; significant progress was made last week; and an announcement could come before the Dodgers fly to Japan to begin their season March 18. The 2025 season will mark Roberts’ 10th with the Dodgers.

“I can’t talk so much about it, but I do think that there’s finally some closure,” Roberts said after Monday’s Cactus League game. “I’m excited. Obviously this is the place I want to be. I’m sure I’ll go into it more. Hopefully there’s an announcement coming soon; I’m waiting. But this is the place I’ve always wanted to be. I just love what we’re doing.”

A cult hero in Boston for the stolen base that helped trigger an unprecedented comeback in the 2004 American League Championship Series, Roberts carved out a 10-year career as a major league outfielder, then spent five years on the San Diego Padres‘ coaching staff. The Dodgers hired Roberts to replace Don Mattingly in November 2015, making him the franchise’s first minority manager.

Since then, Roberts has guided the Dodgers to four National League pennants, eight division titles and a .627 regular-season winning percentage, the highest for someone who has managed at least 250 games. From 2016 to 2024, the Dodgers won 907 regular-season and postseason games. Only the Houston Astros (862) and the New York Yankees (807) even surpassed 800.

The Dodgers won at least 100 regular-season games in five of six full seasons from 2017 to 2023 and finished the 60-game 2020 campaign with a .717 winning percentage. The only year the Dodgers have not won the NL West under Roberts, in 2021, they finished with 106 victories — fewer by one than a San Francisco Giants team they later eliminated in the playoffs. And yet Roberts has only one Manager of the Year Award to his name, a sign of the harsh realities of his job.

For years, the Dodgers’ triumphs have been widely credited to an ownership group with deep pockets and a baseball operations department that is among the most astute in the industry. Roberts, meanwhile, had been left to shoulder the blame for repeated postseason disappointments. That was never more true than in 2019, when another 106-win Dodgers team lost in the NL Division Series to the Washington Nationals after Roberts rode Clayton Kershaw a little too long in a decisive Game 5.

But Roberts went on to manage the Dodgers through an unorthodox 2020 postseason that was staged in a bubble and did not include any days off within series, claiming the franchise’s first title in 32 years and buying himself more time. More October disappointment followed thereafter. The Dodgers were outlasted by the Atlanta Braves in the NLCS in 2021, then were defeated by inferior division rivals in the NLDS in 2022 and 2023, first the Padres and then the Arizona Diamondbacks.

A similar fate seemed to await the Dodgers in 2024. They found themselves a game away from elimination by the Padres in the NLDS, having to win in San Diego to keep their season afloat. A third consecutive early exit, immediately following a first-round bye, would have probably cost Roberts his job. But he managed through a bullpen game in Game 4, then rode more dominant pitching in Game 5 to advance. The Dodgers then breezed past the New York Mets and Yankees to secure their first full-season championship since 1988.

The 2024 season ultimately highlighted Roberts’ best traits. His even-keel demeanor helped the team navigate the betting scandal surrounding Shohei Ohtani‘s then-interpreter, Ippei Mizuhara, early in the year. His trademark positivity kept the team’s spirits high when injuries plagued star players such as Mookie Betts, Max Muncy, Yoshinobu Yamamoto and Tyler Glasnow throughout the summer. And in the fall, while dealing with an extremely compromised starting rotation, Roberts seemed to press all the right buttons.

He navigated through bullpen games on four occasions, most notably to save the season against the Padres and to win the pennant against the Mets. And in Game 5 of the World Series, when starting pitcher Jack Flaherty didn’t pitch past the second inning, Roberts rode a beleaguered group of relief pitchers while the Dodgers made a spirited comeback and entrusted another starter, Walker Buehler, to record the final three outs.

With the win, Roberts put himself alongside Walter Alston and Tommy Lasorda as the only Dodgers managers to win multiple rings. It more than likely secured his place in the Hall of Fame. But what he was most proud of was that the trust he had always extended to his players had been reciprocated.

“That’s everything,” Roberts told ESPN shortly after securing the championship. “I believe in them. And this is the first team that I felt really like the trust went both ways. And that regardless of whatever decision I made, they were going to support me 100 percent.”

The New York Post was first to report Roberts’ extension.

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