Editor’s note: This page will be updated as new data about XBB.1.5 emerges.
A new flavor of the omicron variant of SARS-CoV-2, the virus that causes COVID-19, was identified in October 2022. In the past several weeks, it has steadily gained prominence in the United States. The subvariant is known as XBB.1.5 but has also been given the unofficial nickname “Kraken,” after the mythical sea monster.
Here’s what we know so far about XBB.1.5 so far.
Related: Most widely used COVID-19 vaccines and how they work How did XBB.1.5 emerge and where is it spreading?
Scientists first identified XBB.1.5 in New York state in October 2022, The New York Times reported (opens in new tab) .
The subvariant stems from a broader branch of the omicron family tree known as “XBB,” which emerged as a result of two earlier versions of omicron — BA.2.10.1 and BA.2.75 — swapping genes, according to the World Health Organization (opens in new tab) (WHO). These closely related omicron subvariants had the opportunity to swap genes when they infected the same person at the same time.
From their two parents, XBB viruses gained mutations that helped them evade protective antibodies gained through prior COVID-19 infections and through vaccinations. But there was a tradeoff: XBB viruses simultaneously lost some of their ability to bind tightly to cells, a key step in infection, the New York Times reported. This may explain why other versions of omicron initially outcompeted XBB viruses.
However, as XBB viruses spread, they picked up new mutations and XBB.1.5, a.k.a. the “Kraken,” was born. The Kraken harbors a mutation called F486P, which appears to restore the virus’s ability to tightly latch onto cells, researchers reported Jan. 5 in research posted to the preprint database bioRxiv (opens in new tab) . (This research has not yet been peer-reviewed or published in a scientific journal.)
In a Jan. 4 news conference (opens in new tab) , WHO Director-General Dr. Tedros Adhanom Ghebreyesus (opens in new tab) reported that XBB.1.5 is “on the increase in the U.S. and Europe and has now been identified in more than 25 countries.” Genomic data submitted to the open access database GISAID (opens in new tab) shows that U.S., U.K., Austria, Denmark, Canada, Israel and Germany have detected the most XBB.1.5 sequences so far, and that the subvariant remains relatively rare elsewhere. How easily does it spread?
Available evidence suggests that XBB.1.5 is the “most transmissible” omicron descendent yet detected, Maria Van Kerkhove (opens in new tab) , the WHO’s COVID-19 technical lead, said at a news conference on Jan. 4, according to The New York Times. In the U.S., XBB.1.5 is beginning to gain dominance over other circulating omicron subvariants.
In early December, the Kraken made up an estimated 2% of all COVID-19 cases in the U.S., The Washington Post reported (opens in new tab) . That figure jumped to 40% in the last week of December, STAT reported (opens in new tab) .
The Centers for Disease Control and Prevention (opens in new tab) (CDC) have not yet analyzed all the data from early January 2023, but their current projections suggest that XBB.1.5 accounted for more than 27% of U.S. cases in the first week of the year. In the northeastern U.S., where XBB.1.5 was first detected and remains most common, the subvariant accounts for more than 70% of new cases, according to The Washington Post.
That said, nationwide, other flavors of omicron — namely BQ.1 and BQ.1.1 — were still circulating at comparable levels to XBB.1.5 during the first week of January, the CDC’s projections suggest.Is XBB.1.5 more likely to cause severe disease?
Scientists will need to see many weeks of hospitalization and death data before determining whether XBB.1.5 is more likely to trigger severe disease compared with earlier versions of SARS-CoV-2, the virus that causes COVID-19.
As the U.S. experiences a nationwide surge in COVID-19 infections, “we’re seeing hospitalizations have been notching up overall across the country,” Dr. Barbara Mahon (opens in new tab) , director of CDC’s Coronavirus and Other Respiratory Viruses Division, told NBC News (opens in new tab) . “They don’t appear to be notching up more in the areas that have more XBB.1.5,” which hints that the subvariant isn’t necessarily more likely to cause severe disease than its predecessors. How well do boosters and treatments work against XBB.1.5?
Early data suggests that the so-called bivalent boosters — the two recently updated boosters made by Moderna and Pfizer — offer decent protection against XBB viruses, despite the lineage’s ability to evade antibodies, according to a Dec. 21 report in the New England Journal of Medicine (opens in new tab) .
“Lab studies suggest that the bivalent vaccine is still effective in protecting against severe disease, though perhaps not as much against infection,” Andy Pekosz (opens in new tab) , a professor of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health, said in a statement (opens in new tab) . “XBB.1.5 is derived from the omicron variant BA.2, and while the current bivalent vaccine was developed for the BA.5 variant, it has been shown to generate antibodies that recognize BA.2,” he said.RELATED STORIES—COVID-19 may trigger diabetes by causing fat cells to go haywire
—Brain shrinkage linked to COVID-19
—Belief that COVID-19 was a hoax is a gateway drug to other conspiracy theories
“Things like boosters are always beneficial,” Kristian Andersen (opens in new tab) , a professor in the department of immunology and microbiology who tracks coronavirus variants at the Scripps Research Institute, told The Washington Post. “Even if you get infected, you are expected to have less viral load, and you are expected to be able to transmit the virus less.”
(Notably, as of Jan. 4, less than 16% of eligible U.S. residents had received a bivalent booster, the CDC reported (opens in new tab) .)
Palxovid, an oral antiviral pill used to treat COVID-19, will be effective at treating infections with XBB.1.5, The New York Times reported. The pill may not be prescribed to all COVID-19 patients, as it’s not compatible with certain medications, Pakosz noted, “but overall, for the vast majority of people, Paxlovid is still a good drug to be prescribed if you get COVID-19.”
The bitter war of words between Nigel Farage and Reform MP Rupert Lowe has dramatically escalated with the pair launching fierce new personal attacks on each other.
Mr Farage revealed accusations of bullying by Mr Lowe and accused him of falling out with all his fellow Reform UK MPs, with too many “outbursts” using “inappropriate language”.
And he took the highly unusual step of quoting a Labour minister, Mike Kane, who said after a confrontation with Mr Lowe in the Commons that his anger “showed a man not in charge of his own faculties”.
On Friday, party chairman and Farage lieutenant Zia Yusuf and chief whip Lee Anderson MP disclosed accusations that two female workers had complained of “serious bullying” in Mr Lowe’s offices, and said he had been reported to police over allegations he threatened Mr Yusuf with physical violence.
Mr Lowe, who has been suspended by the parliamentary party, denied the claims.
The worsening of the feud between the Reform UK leader and the millionaire MP for Great Yarmouth came in articles in The Sunday Telegraph in which they both furiously attacked each other.
Lowe alleges ‘witch hunt’
More on Nigel Farage
Related Topics:
Mr Lowe stepped up his verbal onslaught on Mr Farage by claiming that a “witch hunt” against him risked destroying Reform’s attempts at removing Labour from power.
And he claimed that at a time when Reform UK’s poll ratings were rising the attacks on him by the party would be a turn-off to voters, declaring: “Infighting failed the Tories – and it’s failing Reform.”
Mr Farage also began his Telegraph article by claiming: “If the last general election taught us anything, it is that the public does not like political parties that engage in constant infighting.”
But he claimed that thanks to Mr Lowe “unloading a barrage of criticisms against our operations and its main actors”, Reform’s unity has been dented.
Image: Rupert Lowe MP. Pic: PA
‘Containment strategies invariably fail’
Mr Farage said Mr Lowe had “managed to fall out with all his parliamentary colleagues in one way or another”, adding: “We did our best to keep a lid on things but, in the end, containment strategies invariably fail.”
He then referred to a Commons clash with Mr Kane just before Christmas, after Mr Lowe staged a debate about a damaged ship containing toxic cargo docked in his Great Yarmouth constituency.
“Mr Lowe was unhappy with the answer that he received from Mr Kane and, at the end of the debate, he crossed the floor to make his feelings known,” Mr Farage wrote.
“A confrontation ensued. Heated language was heard. The minister’s shoulder was pushed. In the end, the Serjeant at Arms had to step in to calm things down between the two parliamentarians.
“Commenting on Mr Lowe’s conduct later, Mr Kane (said) ‘the anger displayed towards me clearly showed a man not in charge of his own faculties’. Nobody in Reform UK said anything publicly about what had happened. Instead, we carried on.
“Yet the fact is that, sadly, there have been too many similar outbursts from Mr Lowe, often involving the use of inappropriate language, to the despair of our chief whip, Lee Anderson.
“I have been surprised and saddened at this behaviour. Certainly, I never saw anything like it in the European Parliament in 2019 when I was the leader of the Brexit Party and Mr Lowe was an MEP colleague.”
Image: (L-R) Nigel Farage and party chairman Zia Yusuf. Pic: PA
On bullying allegations, Mr Farage wrote: “Last week, the chairman of Reform UK, Zia Yusuf, showed me two letters sent by female members of staff to our party headquarters. Each letter contained an accusation of workplace bullying involving Mr Lowe.
“One of the incidents in question is alleged to have taken place within the parliamentary estate. Both women’s letters stated that these allegations had been reported to the parliamentary authorities.
“As a responsible political party, Reform UK has a duty of care to every single member of staff, whether they are employed by us directly or indirectly.
“With that in mind, I believe that our chairman was entirely right for Reform to appoint a KC to conduct an independent inquiry. It is inconceivable that we could simply ignore such allegations.”
Image: Pic: PA
‘I will not tolerate these falsehoods’
In his Telegraph article, Mr Lowe repeated his claim that there is no credible evidence against him and he was removed from the party before any investigation had started.
“I will not tolerate these falsehoods, and discussions have already taken place with my legal team,” he wrote. “Is it a surprise that these allegations were made public the day after I made reasonable criticisms of Nigel Farage and the Reform leadership?
“It is a witch hunt, plain for all to see. I have been entirely frozen out of the Reform machine over the last few months, in a deliberate and calculated way.”
Without naming Mr Farage, deputy leader Richard Tice or Mr Yusuf, he said the Reform UK leadership was unable even to accept the most mild constructive criticism.
Turning on Mr Yusuf, he wrote: “The allegations against me from the chairman relate to an incident in December, but he only reported them to the police the day after my reasonable questioning was published.
“Take from that what you will. I don’t feel sorry for myself. I feel sorry for the millions of decent British men and women who put their faith in Reform. They deserve better than this vicious charade.”
Spreaker
This content is provided by Spreaker, which may be using cookies and other technologies.
To show you this content, we need your permission to use cookies.
You can use the buttons below to amend your preferences to enable Spreaker cookies or to allow those cookies just once.
You can change your settings at any time via the Privacy Options.
Unfortunately we have been unable to verify if you have consented to Spreaker cookies.
To view this content you can use the button below to allow Spreaker cookies for this session only.
And warning of the damage the feuding was causing, Mr Lowe said: “Everything has been put at risk. Everything. The future of the Right in Britain is now in peril. How can Reform claim to be a party awaiting government when they can’t even follow basic process?
“Reform has been rising in the polls for months. But this spectre of infighting will leave the party looking unserious and turn voters off. Infighting failed the Tories – and it’s failing Reform.”
But Mr Lowe concluded with an olive branch. “On multiple occasions, I have invited Nigel Farage for dinner over the last few months,” he revealed. “Every single one has been refused or ignored.
“Again, I offer a public invitation to Nigel. Let’s have dinner and resolve this in the matter that our members, supporters and country would expect. Any time, any place.”
He added: “I want Reform to be professional, to be fair, to be serious. We must offer a credible alternative to the uniparty that has so failed so spectacularly.
“The leadership’s behaviour this week has undermined that cause, not only in the eyes of the electorate, but also in those of serious individuals across business and industry that any party of government needs to win over.”
Negotiators at Westminster have been trying to persuade a man to come down after he scaled the clock tower which houses Big Ben.
The barefoot man has been spoken to by emergency crews and negotiators a number of times during the day but he remains several metres up the Elizabeth Tower on a ledge where he is holding a Palestinian flag in an apparent protest.
The Metropolitan Police said they were called to the scene in central London at 7.24am on Saturday.
Photographs have shown the man sat on the ledge with the flag and a keffiyeh, a headdress worn by men in the Middle East, wrapped around the decorative stonework on the tower.
A large red stain which appears to be blood can be seen on the side of the tower around the climber’s feet.
Image: The barefoot man is holding a Palestinian flag. Pic: PA
Following the security breach at Parliament, a fire engine later raised an aerial ladder platform to the same height as the man’s position.
Three people standing on the platform have been talking to the man, who is several feet away.
Climber shares videos on social media
The climber has been sharing videos on Instagram from his viewpoint on the tower.
He tells negotiators he will come down “on his own terms”.
In the footage, negotiators appear to raise concerns about an injury to his foot, saying there is “quite a lot of blood” and that his clothes are not warm enough as temperatures drop after sunset.
But the man insists he is safe and says: “I will come down on my own terms, I have said this. But right now I am saying I am safe.
“If you come towards me you are putting me in danger and I will climb higher.”
Instagram
This content is provided by Instagram, which may be using cookies and other technologies.
To show you this content, we need your permission to use cookies.
You can use the buttons below to amend your preferences to enable Instagram cookies or to allow those cookies just once.
You can change your settings at any time via the Privacy Options.
Unfortunately we have been unable to verify if you have consented to Instagram cookies.
To view this content you can use the button below to allow Instagram cookies for this session only.
Also in a video, a woman in plain clothes says: “At some point you have to come down. How long do you think you are going to be there? How long do you think you are able to be there?”
Her voice is then barely audible as she appears to say “your message was to say ‘Free Palestine'” before she encourages him to come down.
In one of the other videos, the man seems to suggest he plans to stay on the ledge for three and a half days.
Image: People in a cherry picker talk to the man
The whole of Westminster Bridge was closed later in the morning as emergency services responded to the incident.
And parliamentary tours on Saturday were cancelled.
Please use Chrome browser for a more accessible video player
0:29
‘Unbelievable he’s up there’
A Metropolitan Police spokesperson said: “Officers are at the scene working to bring the incident to a safe conclusion. They are being assisted by the London Fire Brigade and the London Ambulance Service.”
Bridge Street, which is at the north end of Westminster Bridge, has been closed to allow emergency services to deal with the incident.
Image: Pic: AP
Image: The man before the cherry picker was raised
Image: Pic: PA
At least nine emergency service vehicles have lined the street in central London as crowds look on from beyond a police cordon.
A parliamentary spokesperson said: “We are aware of an incident on the Parliamentary Estate this morning, which is being handled by the Metropolitan Police, assisted by the London Fire Brigade and the London Ambulance Service.
“Parliament takes security extremely seriously, however we do not comment on the specifics of our security measures or mitigations. As a result of this incident, tours of the Parliamentary Estate today have unfortunately had to be cancelled.”
It comes as dozens of people gathered for a pro-Palestinian protest in London.
The crowd assembled on the corner of Parliament Square and appeared to be showing support for the man who climbed up Big Ben.
Trump’s Turnberry golf course vandalised
Please use Chrome browser for a more accessible video player
0:27
‘Gaza not for sale’ on Trump golf course
The protest in Westminster comes as the Palestine Action group said it had sprayed “Gaza is not for sale” on Donald Trump’s Turnberry golf course in Scotland.
Sharing an image of the vandalism on Saturday morning, the group wrote on X: “Whilst Trump attempts to treat Gaza as his own property, he should know his own property is within reach.”
The Turnberry protest comes after the American president claimed the US will “take over the Gaza Strip and we will do a job with it too”.
The HD arm of Hyundai has just released the first official images of the new, battery-electric HX19e mini excavator – the first ever production electric excavator from the global South Korean manufacturer.
The HX19e will be the first all-electric asset to enter series production at Hyundai Construction Equipment, with manufacturing set to begin this April.
The new HX19e will be offered with either a 32 kWh or 40 kWh li-ion battery pack – which, according to Hyundai, is nearly double the capacity offered by its nearest competitor (pretty sure that’s not correct –Ed.). The 40kWh battery allows for up to 6 hours and 40 minutes of continuous operation between charges, with a break time top-up on delivering full shift usability.
Those batteries send power to a 13 kW (17.5 hp) electric motor that drives an open-center hydraulic system. Hyundai claims the system delivers job site performance that is at least equal to, if not better than, that of its diesel-powered HX19A mini excavator.
Advertisement – scroll for more content
To that end, the Hyundai XH19e offers the same 16 kN bucket breakout force and a slightly higher 9.4 kN (just over 2100 lb-ft) dipper arm breakout force. The maximum digging depth is 7.6 feet, and the maximum digging reach is 12.9 feet. Hyundai will offer the new electric excavator with just four selectable options:
enclosed cab vs. open canopy
32 or 40 kWh battery capacity
All HX19es will ship with a high standard specification that includes safety valves on the main boom, dipper arm, and dozer blade hydraulic cylinders, as well as two-way auxiliary hydraulic piping allows the machine to be used with a range of commercially available implements. The hydraulics needed to operate a quick coupler, LED booms lights, rotating beacons, an MP3 radio with USB connectivity, and an operator’s seat with mechanical suspension are also standard.
HX19e electric mini excavator; via Hyundai Construction Equipment.
The ability to operate indoors, underground, or in environments like zoos and hospitals were keeping noise levels down is of critical importance to the success of an operation makes electric equipment assets like these coming from Hyundai a must-have for fleet operators and construction crews that hope to remain competitive in the face of ever-increasing noise regulations. The fact that these are cleaner, safer, and cheaper to operate is just icing on that cake.