A groundbreaking new cancer treatment, hailed by patients as “game-changing”, will be available via the NHS from today.

The drug capivasertib has been shown in trials to slow the spread of the most common form of incurable breast cancer.

Taken in conjunction with an already-available hormonal therapy, it has been shown in trials to double how long treatment will keep the cancer cells from progressing.

“I don’t look at myself anymore as a dying person,” says Elen Hughes, who has been using the drug since February this year.

“I look at myself as a thriving person, who will carry on thriving for as long as I possibly can.”

Mrs Hughes, from North Wales, was first diagnosed with primary breast cancer in 2008.

Eight years later, then aged 46 and with three young children, she was told the cancer had returned and spread.

She says that capivasertib, which she has been able to access via private healthcare, has not only extended her life but improved its quality with fewer side effects than previous medications.

It also delays the need for more aggressive blanket treatments like chemotherapy.

“What people don’t understand is that they might look at the statistics and see that [the therapy] is effective for eight months versus two months, or whatever,” says Mrs Hughes.

“But in cancer, and the land that we live in, really we can do a lot in six months.”

Mrs Hughes says her cancer therapy has allowed her “to see my daughter get married” and believes it is “absolutely brilliant” that the new drug will be available to more patients via the NHS.

The National Institute for Health and Care Excellence approved capivasertib for NHS-use after two decades of research by UK teams.

Professor Nicholas Turner, from the Institute of Cancer Research which led the study, told Sky News it was a “great success story for British science”.

The new drug is suitable for patients’ tumours with mutations or alterations in the PIK3CA, AKT1 or PTEN genes, which are found in approximately half of patients with advanced breast cancer.

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Prof Turner says hundreds of patients could see the benefit in the immediate future, with thousands more people identified over time.

“We need new drugs that will help our existing therapies work for longer, and that’s where this new drug, capivasertib comes in,” says Prof Turner.

“It doubles how long hormone therapy treatment works for, giving patients precious extra time with their families.”

He called for urgent genetic testing of patients with advanced breast cancers to see if they could benefit.

With £99 a month to live off Aida has turned to a food bank.

“It’s very difficult. Extremely difficult. But I have to live,” says Aida Mascarenhas. The 75-year-old tells us £99 is all she has left after paying her bills. Aida’s accommodation is provided by the local authority.

“Ninety-nine pounds in a month – even for bedding, pillows or something. So many things for a house.”

At the food bank, Aida is called forward to collect handouts to get her through the week.

It’s three years since we last visited this food bank at the Marks Gate Community Hub in Romford, Essex, when the cost of living crisis was being described as the worst in a generation.

After three grinding years of making ends meet, the food bank organiser – and her clients – tell us things aren’t improving. In fact, they feel things have got even worse.

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“Overall the cost of living crisis has gone up considerably since three years ago. It’s worse,” says Asma Haq, founder of the Marks Gate Relief Project.

“For charities like us it was a storm anyway and now it’s a hurricane. We are busy non-stop.”

Asma is running around calling people forward – offering them basics like potatoes, pasta and spices.

She tells us some always come early, anxious the supplies will run out.

Next in line at the food bank is a woman dragging a large suitcase – pulling the zip back to shove in a large bottle of cooking oil and anything else the food bank will give her.

Asma describes almost all the people who come to the hub as non-white British, first-generation migrants.

She says most have broken or no English with little to no computer skills and want help to access a changing benefits system.

“It’s also about so many other barriers they face. A lot aren’t tech-savvy. They used to get a lot of council tax support which has been reduced considerably.

We’ve had people literally put their phones in our faces and say ‘do it for us’.”

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The threads of why people say they’re struggling weave through all communities. Across the road from the community centre we talk to people who again and again tell us they feel the cost of living has been forgotten about.

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One woman tells us: “I don’t know how people are going to live. They keep putting it up and up and up. It’s everything. You’re worrying about the gas bill, the electric bill, the council bill.

“And I know people that’s desperate and they cannot pay their bills and they’re worried about ending up in court.”

Continuing to retrace our steps from three years ago, we head back to Barking in east London and revisit a launderette where we meet a familiar face – Myriam Sinon who has worked in the business for the last 10 years.

I ask her if she imagined we would be standing here three years after we last met and things wouldn’t have improved.

“I didn’t expect that it would be worse,” she says.

Myriam says electricity prices have quadrupled in the past three years – but the launderette has not increased prices, fearing it would drive customers away.

Everyone needs to wash things and she says people are finding ways to share the cost – gathering up washing from people they know to create a maximum load for the machines.

People are hoping to see an end in sight. But Myriam has a stark prediction if things don’t improve.

“There will be crime every time,” she says. “When people don’t get enough money they start stealing. They might kill you for a watch or phone.”

The government will fund any further local inquiries into the grooming gangs scandal that are deemed necessary, Sir Keir Starmer has said.

However, the prime minister said it is his “strong belief” that the focus must be on implementing recommendations from the Alexis Jay national review before more investigations go ahead.

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It follows a row over whether Labour is still committed to the five local inquiries it promised in January, after safeguarding minister Jess Phillips failed to provide an update on them in a statement to parliament hours before it closed for recess on Tuesday.

Instead, Ms Phillips told MPs that local authorities will be able to access a £5m fund to support locally-led work on grooming gangs.

On Thursday morning, Home Secretary Yvette Cooper insisted the “victim-centred, locally-led inquiries” will still go ahead, while a Home Office source told Sky News more could take place in addition to the five.

Speaking to Sky News’ Rob Powell later on Thursday, Sir Keir confirmed that there could be more inquiries than those five but said the government must also “get on and implement the recommendations we’ve already got”.

The prime minister said: “Of course, if there’s further local inquiries that are needed then we will put some funding behind that, and they should happen.

“But I don’t think that simply saying we need more inquiries when we haven’t even acted on the ones that we’ve had is necessarily the only way forward.”

Ms Phillips’s earlier comments led to accusations that the government was diluting the importance of the local inquiries by giving councils choice over how to use the funds.

Sky News understands she was due to host a briefing with MPs this afternoon at 5pm – the second she had held in 24 hours – in an attempt to calm concern amongst her colleagues.

Review recommendations ‘sat on a shelf’

Sir Keir insisted he is not watering down his commitment for the five local enquiries, but said the Jay recommendations were “sitting on a shelf under the last government” and he is “equally committed” to them.

He added: “At the most important level, if there is evidence of grooming that is coming to light now, we need a criminal investigation. I want the police investigation because I want perpetrators in the dock and I want justice delivered.”

In October 2022, Professor Alexis Jay finished a seven-year national inquiry into the many ways children in England and Wales had been sexually abused, including grooming gangs.

Girls as young as 11 were groomed and raped across a number of towns and cities in England over a decade ago.

Prof Jay made 20 recommendations which haven’t been implemented yet, with Sir Keir saying on Thursday he will bring 17 of them forward.

However, the Tories and Reform UK want the government to fund a new national inquiry specifically into grooming gangs, demands for which first started last year after interventions by tech billionaire Elon Musk on his social media platform X.

‘Fuelling confusion’

Reform leader Nigel Farage said the statement made by Ms Phillips “was one of the most cowardly things I have ever seen” as he repeated calls for a fresh inquiry.

Robert Jenrick, the shadow justice secretary, also told Sky News that ministers were “fuelling confusion” and that the “mess.. could have been avoided if the government backed a full national inquiry – not this piecemeal alternative”.

Tory leader Kemi Badenoch said the government needed to look at “state failings” and she would try and force a fresh vote on holding another national inquiry, which MPs voted down in January.

‘Political mess’

As well as facing criticism from the Opposition, there are signs of a backlash within Labour over how the issue has been handled.

Labour MPs angry with government decision grooming gangs

Mhari Aurora

Political correspondent

@MhariAurora

With about an hour until the House of Commons rose for Easter recess, the government announced it was taking a more “flexible” approach to the local grooming gang inquiries.

Safeguarding minister Jess Philips argued this was based on experience from certain affected areas, and that the government is funding new police investigations to re-open historic cases.

Speaking on Times Radio, former chair of the Equality and Human Rights Commission Sir Trevor Phillips called the move “utterly shameful” and claimed it was a political decision.

One Labour MP told Sky News: “Some people are very angry. I despair. I don’t disagree with many of our decisions but we just play to Reform – someone somewhere needs sacking.”

The government has insisted party political misinformation was fanning the flames of frustration in Labour.

The government also said it was not watering down the inquiries and was actually increasing the action being taken.

But while many Labour MPs have one eye on Reform in the rearview mirror, any accusations of being soft on grooming gangs only provides political ammunition to their adversaries.

One Labour MP told Sky News the issue had turned into a “political mess” and that they were being called “grooming sympathisers”.

On the update from Ms Phillips on Tuesday, they said it might have been the “right thing to do” but that it was “horrible politically”.

“We are all getting so much abuse. It’s just political naivety in the extreme.”

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‘We will leave no stone unturned’

Ms Phillips later defended her decision, saying there was “far too much party political misinformation about the action that is being taken when everyone should be trying to support victims and survivors”.

“We are funding new police investigations to re-open historical cases, providing national support for locally led inquiries and action, and Louise Casey… is currently reviewing the nature, scale and ethnicity of grooming gangs offending across the country,” she said.

“We will not hesitate to go further, unlike the previous government, who showed no interest in this issue over 14 years and did nothing to progress the recommendations from the seven-year national inquiry when they had the chance.

“We will leave no stone unturned in pursuit of justice for victims and will be unrelenting in our crackdown on sick predators and perpetrators who prey on vulnerable children.”