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OpenAI CEO Sam Altman speaks during a keynote address announcing ChatGPT integration for Bing at Microsoft in Redmond, Washington, on February 7, 2023.

Jason Redmond | AFP | Getty Images

Before OpenAI’s ChatGPT emerged and captured the world’s attention for its ability to create compelling sentences, a small startup called Latitude was wowing consumers with its AI Dungeon game that let them use artificial intelligence to create fantastical tales based on their prompts.

But as AI Dungeon became more popular, Latitude CEO Nick Walton recalled that the cost to maintain the text-based role-playing game began to skyrocket. AI Dungeon’s text-generation software was powered by the GPT language technology offered by the Microsoft-backed AI research lab OpenAI. The more people played AI Dungeon, the bigger the bill Latitude had to pay OpenAI.

Compounding the predicament was that Walton also discovered content marketers were using AI Dungeon to generate promotional copy, a use for AI Dungeon that his team never foresaw, but that ended up adding to the company’s AI bill.

At its peak in 2021, Walton estimates Latitude was spending nearly $200,000 a month on OpenAI’s so-called generative AI software and Amazon Web Services in order to keep up with the millions of user queries it needed to process each day.

“We joked that we had human employees and we had AI employees, and we spent about as much on each of them,” Walton said. “We spent hundreds of thousands of dollars a month on AI and we are not a big startup, so it was a very massive cost.”

By the end of 2021, Latitude switched from using OpenAI’s GPT software to a cheaper but still capable language software offered by startup AI21 Labs, Walton said, adding that the startup also incorporated open source and free language models into its service to lower the cost. Latitude’s generative AI bills have dropped to under $100,000 a month, Walton said, and the startup charges players a monthly subscription for more advanced AI features to help reduce the cost.

Latitude’s pricey AI bills underscore an unpleasant truth behind the recent boom in generative AI technologies: The cost to develop and maintain the software can be extraordinarily high, both for the firms that develop the underlying technologies, generally referred to as a large language or foundation models, and those that use the AI to power their own software.

The high cost of machine learning is an uncomfortable reality in the industry as venture capitalists eye companies that could potentially be worth trillions, and big companies such as Microsoft, Meta, and Google use their considerable capital to develop a lead in the technology that smaller challengers can’t catch up to. 

But if the margin for AI applications is permanently smaller than previous software-as-a-service margins, because of the high cost of computing, it could put a damper on the current boom. 

The high cost of training and “inference” — actually running — large language models is a structural cost that differs from previous computing booms. Even when the software is built, or trained, it still requires a huge amount of computing power to run large language models because they do billions of calculations every time they return a response to a prompt. By comparison, serving web apps or pages requires much less calculation.

These calculations also require specialized hardware. While traditional computer processors can run machine learning models, they’re slow. Most training and inference now takes place on graphics processors, or GPUs, which were initially intended for 3D gaming, but have become the standard for AI applications because they can do many simple calculations simultaneously. 

Nvidia makes most of the GPUs for the AI industry, and its primary data center workhorse chip costs $10,000. Scientists that build these models often joke that they “melt GPUs.”

Training models

Nvidia A100 processor

Nvidia

Analysts and technologists estimate that the critical process of training a large language model such as OpenAI’s GPT-3 could cost more than $4 million. More advanced language models could cost over “the high-single-digit millions” to train, said Rowan Curran, a Forrester analyst who focuses on AI and machine learning.

Meta’s largest LLaMA model released last month, for example, used 2,048 Nvidia A100 GPUs to train on 1.4 trillion tokens (750 words is about 1,000 tokens), taking about 21 days, the company said when it released the model last month. 

It took about 1 million GPU hours to train. With dedicated prices from AWS, that would cost over $2.4 million. And at 65 billion parameters, it’s smaller than the current GPT models at OpenAI, like ChatGPT-3, which has 175 billion parameters. 

Clement Delangue, the CEO of AI startup Hugging Face, said the process of training the company’s Bloom large language model took more than two-and-a-half months and required access to a supercomputer that was “something like the equivalent of 500 GPUs.”

Organizations that build large language models must be cautious when they retrain the software, which helps improve its abilities, because it costs so much, he said.

“It’s important to realize that these models are not trained all the time, like every day,” Delangue said, noting that’s why some models, such as ChatGPT, don’t have knowledge of recent events. ChatGPT’s knowledge stops in 2021, he said.

“We are actually doing a training right now for the version two of Bloom and it’s gonna cost no more than $10 million to retrain,” Delangue said. “So that’s the kind of thing that we don’t want to do every week.”

Inference and who pays for it

Bing with Chat

Jordan Novet | CNBC

To use a trained machine learning model to make predictions or generate text, engineers use the model in a process called “inference,” which can be much more expensive than training because it might need to run millions of times for a popular product.

For a product as popular as ChatGPT — which investment firm UBS estimates to have reached 100 million monthly active users in January — Curran believes that it could have cost OpenAI $40 million to process the millions of prompts people fed into the software that month.

Costs skyrocket when these tools are used billions of times a day. Financial analysts estimate Microsoft’s Bing AI chatbot, which is powered by an OpenAI ChatGPT model, needs at least $4 billion of infrastructure to serve responses to all Bing users.

In the case of Latitude, for instance, while the startup didn’t have to pay to train the underlying OpenAI language model it was accessing, it had to account for the inferencing costs that were something akin to “half-a-cent per call” on “a couple million requests per day,” a Latitude spokesperson said.

“And I was being relatively conservative,” Curran said of his calculations.

In order to sow the seeds of the current AI boom, venture capitalists and tech giants have been investing billions of dollars into startups that specialize in generative AI technologies. Microsoft, for instance, invested as much as $10 billion into GPT’s overseer OpenAI, according to media reports in January. Salesforce‘s venture capital arm, Salesforce Ventures, recently debuted a $250 million fund that caters to generative AI startups.

As investor Semil Shah of the VC firms Haystack and Lightspeed Venture Partners described on Twitter, “VC dollars shifted from subsidizing your taxi ride and burrito delivery to LLMs and generative AI compute.”

Many entrepreneurs see risks in relying on potentially subsidized AI models that they don’t control and merely pay for on a per-use basis.

“When I talk to my AI friends at the startup conferences, this is what I tell them: Do not solely depend on OpenAI, ChatGPT or any other large language models,” said Suman Kanuganti, founder of personal.ai, a chatbot currently in beta mode. “Because businesses shift, they are all owned by big tech companies, right? If they cut access, you’re gone.”

Companies such as enterprise tech firm Conversica are exploring how they can use the tech through Microsoft’s Azure cloud service at its currently discounted price.

While Conversica CEO Jim Kaskade declined to comment about how much the startup is paying, he conceded that the subsidized cost is welcome as it explores how language models can be used effectively.

“If they were truly trying to break even, they’d be charging a hell of a lot more,” Kaskade said.

How it could change

Nvidia expanded from gaming into A.I. Now the big bet is paying off as its chips power ChatGPT

It’s unclear if AI computation will stay expensive as the industry develops. Companies making the foundation models, semiconductor makers and startups all see business opportunities in reducing the price of running AI software.

Nvidia, which has about 95% of the market for AI chips, continues to develop more powerful versions designed specifically for machine learning, but improvements in total chip power across the industry have slowed in recent years.

Still, Nvidia CEO Jensen Huang believes that in 10 years, AI will be “a million times” more efficient because of improvements not only in chips, but also in software and other computer parts.

“Moore’s Law, in its best days, would have delivered 100x in a decade,” Huang said last month on an earnings call. “By coming up with new processors, new systems, new interconnects, new frameworks and algorithms, and working with data scientists, AI researchers on new models, across that entire span, we’ve made large language model processing a million times faster.”

Some startups have focused on the high cost of AI as a business opportunity.

“Nobody was saying ‘You should build something that was purpose-built for inference.’ What would that look like?” said Sid Sheth, founder of D-Matrix, a startup building a system to save money on inference by doing more processing in the computer’s memory, as opposed to on a GPU.

“People are using GPUs today, NVIDIA GPUs, to do most of their inference. They buy the DGX systems that NVIDIA sells that cost a ton of money. The problem with inference is if the workload spikes very rapidly, which is what happened to ChatGPT, it went to like a million users in five days. There is no way your GPU capacity can keep up with that because it was not built for that. It was built for training, for graphics acceleration,” he said.

Delangue, the HuggingFace CEO, believes more companies would be better served focusing on smaller, specific models that are cheaper to train and run, instead of the large language models that are garnering most of the attention.

Meanwhile, OpenAI announced last month that it’s lowering the cost for companies to access its GPT models. It now charges one-fifth of one cent for about 750 words of output.

OpenAI’s lower prices have caught the attention of AI Dungeon-maker Latitude.

“I think it’s fair to say that it’s definitely a huge change we’re excited to see happen in the industry and we’re constantly evaluating how we can deliver the best experience to users,” a Latitude spokesperson said. “Latitude is going to continue to evaluate all AI models to be sure we have the best game out there.”

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Anne Wojcicki has a new offer to take 23andMe private, this time for $74.7 million

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Anne Wojcicki has a new offer to take 23andMe private, this time for .7 million

Anne Wojcicki attends the WSJ Magazine Style & Tech Dinner in Atherton, California, on March 15, 2023.

Kelly Sullivan | Getty Images Entertainment | Getty Images

23andMe CEO Anne Wojcicki and New Mountain Capital have submitted a proposal to take the embattled genetic testing company private, according to a Friday filing with the U.S. Securities and Exchange Commission.

Wojcicki and New Mountain have offered to acquire all of 23andMe’s outstanding shares in cash for $2.53 per share, or an equity value of approximately $74.7 million. The company’s stock closed at $2.42 on Friday with a market cap of about $65 million.

The offer comes after a turbulent year for 23andMe, with the stock losing more than 80% of its value in 2024. In January, the company announced plans to explore strategic alternatives, which could include a sale of the company or its assets, a restructuring or a business combination. 

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23andMe has a special committee of independent directors in place to evaluate potential paths forward. The company appointed three new independent directors to its board in October after all seven of its previous directors abruptly resigned the prior month. The special committee has to approve Wojcicki and New Mountain’s proposal.

“We believe that our Proposal provides compelling value and immediate liquidity to the Company’s public stockholders,” Wojcicki and Matthew Holt, managing director and president of private equity at New Mountain, wrote in a letter to the special committee on Thursday.

Wojcicki previously submitted a proposal to take the company private for 40 cents per share in July, but it was rejected by the special committee, in part because the members said it lacked committed financing and did not provide a premium to the closing price at the time.

Wojcicki and New Mountain are willing to provide secured debt financing to fund 23andMe’s operations through the transaction’s closing, the filing said. New Mountain is based in New York and has $55 billion of assets under management, according to its website.

23andMe declined to comment.

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Shares of Hims & Hers tumble 23% after FDA says semaglutide is no longer in shortage

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Shares of Hims & Hers tumble 23% after FDA says semaglutide is no longer in shortage

Hims & Hers

Shares of Hims & Hers Health tumbled more than 23% on Friday after the U.S. Food and Drug Administration announced that the shortage of semaglutide injection products has been resolved.

Semaglutide is the active ingredient in Novo Nordisk‘s blockbuster weight loss drug Wegovy and diabetes treatment Ozempic. Those medications are part of a class of drugs called GLP-1s, and demand for the treatments has exploded in recent years. As a result, digital health companies such as Hims & Hers have been prescribing compounded semaglutide as an alternative for patients who are navigating volatile supply hurdles and insurance obstacles.

Compounded drugs are custom-made alternatives to brand-name drugs designed to meet a specific patient’s needs, and compounders are allowed to produce them when brand-name treatments are in shortage. The FDA doesn’t review the safety and efficacy of compounded products.

Hims & Hers began offering compounded semaglutide to patients in May, and it owns compounding pharmacies that produce the medications.

Compounded medications are typically much cheaper than their branded counterparts. Hims & Hers sells compounded semaglutide for less than $200 per month, while Ozempic and Wegovy both cost around $1,000 per month without insurance.

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The FDA said Friday that it will start taking action against compounders for violations in the next 60 to 90 days, depending on the type of facility, in order to “avoid unnecessary disruption to patient treatment.”

“Now that the FDA has determined the drug shortage for semaglutide has been resolved, we will continue to offer access to personalized treatments as allowed by law to meet patient needs,” Hims & Hers CEO Andrew Dudum posted Friday on X. “We’re also closely monitoring potential future shortages, as Novo Nordisk stated two weeks ago that it would continue to have ‘capacity limitations’ and ‘expected continued periodic supply constraints and related drug shortage notifications.'”

Him & Hers’ weight loss offerings have been a massive hit with investors. Shares of the company climbed more than 200% last year, and the stock is already up more than 100% this year despite Friday’s move.

Even before it added compounded GLP-1s to its portfolio, the company said in its 2023 fourth-quarter earnings call that it expects its weight loss program to bring in more than $100 million in revenue by the end of 2025.

Despite the turbulent regulatory landscape, Hims & Hers has showed no signs of slowing down.

On Friday, the company announced it has acquired a U.S.-based peptide facility that will “further verticalize the company’s long-term ability to deliver personalized medications.” Hims & Hers will explore advances across metabolic optimization, recovery science, biological resistances, cognitive performance and preventative health through the acquisition, the company said.

That move comes just days after Hims & Hers also bought Trybe Labs, the New Jersey-based at-home lab testing facility. Trybe Labs will allow Hims & Hers to perform at-home blood draws and more comprehensive pretreatment testing.

Hims & Hers did not disclose the terms of either deal.

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Tesla recalls more than 375,000 vehicles in U.S. due to failing power-assisted steering systems

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Tesla recalls more than 375,000 vehicles in U.S. due to failing power-assisted steering systems

Tesla models Y and 3 are displayed at a Tesla dealership in Corte Madera, California, on Dec. 20, 2024.

Justin Sullivan | Getty Images

Tesla is voluntarily recalling 376,241vehicles in the U.S. to correct an issue with failing power-assisted steering systems, according to records posted to the website of the U.S. National Highway Traffic Safety Administration.

In a safety recall report posted on the NHTSA website, Tesla said the recall includes Model 3 and Model Y vehicles that were manufactured for sale in the U.S. from Feb. 28, 2023, to October 11, 2023, and that were equipped with a certain older software release.

The records said printed circuit boards in the steering systems in affected vehicles could become overstressed, causing the power-assist steering to fail in some cases when a Tesla vehicle rolled to a stop and then accelerated.

When electronic power-assist steering systems fail in a Tesla, drivers need to exert more force to steer their cars, which can increase the risk of a collision.

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Tesla told the vehicle safety regulator that it was not aware of any crashes, injuries or deaths related to the power steering failures, and that it was offering an over-the-air software update as a remedy.

The recall follows an earlier related probe and voluntary recall in China concerning the same systems.

President Donald Trump has appointed Tesla CEO Elon Musk to lead a team that is slashing the federal government workforce, and in some cases, regulations and entire agencies. Those cuts already affected the NHTSA, an agency Musk has long seen as standing in the way of some of his ambitions at Tesla.

The regulator has been engaged in a yearslong investigation into safety defects in the systems that Tesla markets currently as its Autopilot and Full Self-Driving (Supervised) options. The features do not make Tesla cars into robotaxis. They require a human driver ready to steer or brake at any time.

The Washington Post reported on Thursday that Musk’s team has led mass firings at the NHTSA, reducing the agency’s workforce and capacity to investigate companies including Tesla by about 10%.

Tesla didn’t respond to a request for comment.

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