A gene mutation which increases the risk of breast and ovarian cancer has been linked to people with Orkney heritage.
Scientists from the universities of Aberdeen and Edinburgh have found that one in 100 people with grandparents from the islands off the north-eastern coast of Scotland, have a mutation of the gene BRCA1.
It is likely the gene variant came from one of the founding members of Westray – an Orkney island which has a population of under 600 people – at least 250 years ago, according to the research.
The gene mutation was repeatedly spotted in women from Orkney who have the cancers, most of whom could also trace their family ancestry back to the small island of Westray.
As a result of the findings, planning is under way to offer free testing for the gene variant to anyone living on the Scottish islands with a Westray-born grandparent, regardless of their family history with the disease.
Professor Zosia Miedzybrodzka, director of NHS North of Scotland Genetic Service, made it clear that developing cancer is not solely down to carrying the BRCA1 variant alone.
What is a BRCA1 gene?
Genes are found in every cell in our body. They enable bodies to grow and function correctly.
BRCA1 is a tumour suppressor gene that helps to protect us from developing cancer, according to the NHS.
A variation can affect the function of the gene. This can increase the chance of developing breast, ovarian or prostate cancer, which is more likely to occur at a younger age.
A person’s genes can be examined from a blood sample. However, currently, it is usually only offered to families with a strong history of cancers.
Everyone has the BRCA genes, but not everyone has mutations in them.
“There are many complex factors, and some people with gene alterations will not get cancer,” Prof Miedzybrodzka said. “However, we know that testing and the right follow-up can save lives.”
She recommended things like risk-reducing surgery, breast screening with MRI from the age of 30 and lifestyle advice to improve the health of women with the gene mutation.
Awareness of the faulty gene was raised when Hollywood actress Angelina Jolie underwent a double mastectomy a decade ago, after losing her mother to ovarian cancer and then discovering she had a BRCA1 variant.
The NHS recommends talking to your GP if cancer runs in the family, or if you are worried about your own risk. They may refer you for a genetics test, which will tell you if you have inherited one of the cancer risk genes.
Migrants convicted of sex offences in the UK or overseas will be unable to claim asylum under government plans to change the law to improve border security.
The Home Office announcement means foreign nationals who are added to the sex offenders register will forfeit their rights to protection under the Refugee Convention.
As part of the 1951 UN treaty, countries are allowed to refuse asylum to terrorists, war criminals and individuals convicted of a “particularly serious crime” – which is currently defined in UK law as an offence carrying a sentence of 12 months or more.
The government now plans to extend that definition to include all individuals added to the Sex Offenders’ Register, regardless of the length of sentence, in an amendment to the Border Security, Asylum and Immigration Bill, which is currently going through parliament. It’s understood they also hope to include those convicted of equivalent crimes overseas.
Those affected will still be able to appeal their removal from the UK in the courts under the European Convention on Human Rights (ECHR).
Image: More than 10,000 people have now been detected crossing the Channel. Pic: PA
It is unclear how many asylum seekers will be affected, as the government has been unable to provide any projections or past data on the number of asylum seekers added to the Sex Offenders’ Register.
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Home Secretary Yvette Cooper said: “Sex offenders who pose a risk to the community should not be allowed to benefit from refugee protections in the UK.
“We are strengthening the law to ensure these appalling crimes are taken seriously.”
Safeguarding and Violence Against Women and Girls Minister Jess Philips said: “We are determined to achieve our mission of halving violence against women and girls in a decade.
“That’s exactly why we are taking action to ensure there are robust safeguards across the system, including by clamping down on foreign criminals who commit heinous crimes like sex offences.”
The Home Office would like voters to see this as a substantial change. But that’s hard to demonstrate without providing any indication of the scale of the problem it seeks to solve.
Clearly, the government does not want to fan the flames of resentment towards asylum seekers by implying large numbers have been committing sex crimes.
But amid rising voter frustration about the government’s grip on the issue, and under pressure from Reform – this measure is about signalling it is prepared to take tough action.
Conservatives: ‘Too little, too late’
The Conservatives claim Labour are engaged in “pre-election posturing”.
Chris Philp MP, the shadow home secretary, said: “This is too little, too late from a Labour government that has scrapped our deterrent and overseen the worst year ever for small boat crossings – with a record 10,000 people crossing this year already.
“Foreign criminals pose a danger to British citizens and must be removed, but so often this is frustrated by spurious legal claims based on human rights claims, not asylum claims.”
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Has Labour tackled migration?
The Home Office has also announced plans to introduce a 24-week target for appeal hearings (known as “first-tier tribunals”) to be held for rejected asylum seekers living in taxpayer-supported accommodation, or for foreign national offenders.
The current average wait is 50 weeks. The idea is to cut the asylum backlog and save taxpayers money – Labour have committed to end the use of asylum hotels by the end of this parliament.
It’s unclear how exactly this will be achieved, although a number of additional court days have already been announced.
The government also plans to crack down on fake immigration lawyers who advise migrants on how to lodge fraudulent asylum claims, with the Immigration Advice Authority given new powers to issue fines of up to £15,000.
A 14-year-old girl who attempted to murder two teachers and a pupil at a school in Wales has been sentenced to 15 years in detention.
The girl, who cannot be named for legal reasons, was previouslyfound guilty of attempting to murder teachers Fiona Elias and Liz Hopkin and a pupil at Ysgol Dyffryn Aman in Ammanford.
Emergency services were called to the school on 24 April last year, in what the trial heard was a “serious episode of violence” during the mid-morning break after the girl took her father’s fishing “multi-tool” to school.
She had admitted to three counts of wounding with intent and possession of a bladed article on a school premises, but a jury found her guilty of attempted murder in February after a week-long trial.
Following her arrest, the teenager told officers she was “pretty sure” the incident would be on the news, and added “that’s one way to be a celebrity”.
Both Mrs Elias and Mrs Hopkin “received significant and serious injuries”, Swansea Crown Court heard.
Mrs Hopkin was airlifted to the University Hospital of Wales in Cardiff after she sustained “four stab wounds”, while Mrs Elias and the pupil also attended hospital for treatment.
Image: Ammanford in Carmarthenshire
‘Changed my life forever’
Reading her victim personal statement from the witness box on Monday, Fiona Elias said the incident had shown her that life was “fragile” and had been “a steep learning curve”.
“Walking out on duty that day would change my life forever,” she said – a moment which “replays itself over and over no matter how much time passes”.
“It’s not easy, and I know I’ll continue to face challenges, but every day I’m taking step towards healing,” Mrs Elias said.
Addressing the defendant, Mrs Elias said “your motive was clear, you intended to murder me” but that she was stopped “thanks to Liz’s selfless actions”.
She said she was not “ruling out the possibility of a meeting with [the pupil] in the future,” but that she first needed to know she would “engage with the interventions that will be put in place”.
Outlining her plans to campaign for safer working conditions at schools, Mrs Elias said: “I never expected to give my blood, but I will always give my heart to Ysgol Dyffryn Aman and to the world of education.”
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The teenager, who can’t be named, is due to be sentenced in April.
‘Right place at the right time’
Liz Hopkin said it had been “the worst experience of [her] life” but that she was “glad” she was “in the right place at the right time” to protect Mrs Elias.
“I’m still here, I’m still alive, though at the time I was sure that I was going to die,” she told the court.
“Physically, my wounds have healed but the scars remain.”
Mrs Hopkin added that the thought of returning to a career in teaching now filled her with “anxiety and dread”.
“You were prepared to kill someone you did not know,” she said, addressing the defendant, who sat in the court for proceedings, until she moved to the dock for sentence.
“The decision to end my life was never yours to make.”
But Mrs Hopkin said she worried about the defendant’s future, adding: “I don’t want you to be punished forever but I do want you to take every opportunity to make your life better.”
Concluding her victim personal statement, Mrs Hopkin said: “It has changed me in ways I never wanted and that is something I will have to live with for the rest of my life.”
Image: Pic: PA
‘Very complex young girl’
Prosecuting, William Hughes KC said aggravating factors in the case included use of a knife, the fact two of the victims were “carrying out a public service” and that the offending took place in public.
In mitigation, Caroline Rees KC said the defendant was “a very complex young girl”.
She said she had shown remorse, had a “difficult background” and also the fact there were two trials.
Handing down his sentence, Judge Paul Thomas said the defendant would serve half of the 15-year sentence before she can be considered for release.
Addressing the defendant, he said: “What you did in school almost a year ago the day has caused a large number of people a great deal of harm and upset. It has hugely affected many lives, including, of course, your own.”
“The simple fact is you tried to kill three people, two teachers and another pupil,” he added.
“I think that it is very important here that what you did you did in full of so many other pupils…In my view you wanted as many of your fellow pupils as possible to see what you intended to do.”
The Judge added that “for one reason or other, [the defendant wasn’t] really listening” to the victim impact statements of Mrs Elias and Mrs Hopkin.
He said he did not think the teenager was “genuinely sorry” for what she did, adding: “You showed no emption or even interest in how they felt that day or ever since.”