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COVID-19 affects people differently, in terms of infection with the virus SARS-CoV-2 and mortality rates. In this Special Feature, we focus on some of the sex differences that characterize this pandemic. Share on Pinterest The data that are available so far indicate that there are significant differences between how the sexes respond to the new coronavirus.

All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. Visit our coronavirus hub for the most recent information on the COVID-19 pandemic.

There are many ways in which the pandemic itself affects peoples day-to-day lives, and gender understood as the ensemble of social expectations, norms, and roles we associate with being a man, woman, trans- or nonbinary person plays a massive part.

On a societal level, COVID-19 has affected cis- and transwomen, for example, differently to how it has cismen, transmen, and nonbinary people. Reproductive rights, decision making around the pandemic, and domestic violence are just some key areas where the pandemic has negatively impacted women.

However, sex differences understood as the biological characteristics we associate with the sex that one is assigned at birth also play an undeniable role in an epidemic or pandemic.

While sex and gender are, arguably, inextricably linked in healthcare, as in every other area of our lives, in this Special Feature, we will focus primarily on the infection rates of SARS-CoV-2 and the mortality rates that COVID-19 causes, broken down by sex.

In specialized literature, these effects fall under the umbrella term of primary effects of the pandemic, while the secondary impact of the pandemic has deeper social and political implications.

Throughout this feature, we use the binary terms man and woman to accurately reflect the studies and the data they use. Sex-disaggregated data lacking

Before delving deeper into the subject of sex differences in COVID-19, it is worth noting that the picture is bound to be incomplete, as not all countries have released their sex-disaggregated data.

A report appearing on the blog of the journal BMJ Global Health on March 24, 2020, reviewed data from 20 countries that had the highest number of confirmed cases of COVID-19 at the time.

Of these 20 countries, Belgium, Malaysia, Netherlands, Portugal, Spain, United Kingdom, and the United States of America did not provide data that was disaggregated, or broken down, by sex.

At the time, the authors of the BMJ report appealed to these countries and others to provide sex specific data.

Anna Purdie, from the University College London, United Kingdom, and her colleagues, noted: We applaud the decision by the Italian government to publish data that are fully sex- and age-disaggregated. Other countries [] are still not publishing national data in this way. We understand but regret this oversight.
At a minimum, we urgently call on countries to publicly report the numbers of diagnosed infections and deaths by sex. Ideally, countries would also disaggregate their data on testing by sex.

Anna Purdie et al.

Since then, countries that include Belgium, the Netherlands, Portugal, and Spain have made their data available.

The U.K. have made only a part of the sex-disaggregated data available for England and Wales, without covering Scotland and Northern Ireland while Malaysia and the U.S. have not made their sex-disaggregated data available at all.

At the time of writing this article, the U.S. still have not released their sex-disaggregated data despite the country having the highest number of COVID-19 cases in the world.

For more research-backed information and resources for mens health, please visit our dedicated hub. Men more than twice as likely to die

Global Health 5050, an organization that promotes gender equality in healthcare, has rounded up the total and partial data that is available from the countries with the highest numbers of confirmed COVID-19 cases.

According to their data gathering, the highest ratio of male to female deaths, as a result of COVID-19, is in Denmark and Greece: 2.1 to 1.

In these countries, men are more than twice as likely to die from COVID-19 as women. In Denmark, 5.7% of the total number of cases confirmed among men have resulted in death, whereas 2.7% of women with confirmed COVID-19 have died.

In the Republic of Ireland, the male to female mortality ratio is 2 to 1, while Italy and Switzerland have a 1.9 to 1 ratio each.

The greatest parity between the genders from countries that have submitted a full set of data are Iran, with 1.1 to 1, and Norway, with 1.2 to 1.

In Iran, 5.4% of the women patients have died, compared with 5.9% of the men. In Norway, these numbers stand at 1.3% and 1.1%, respectively.

China has a ratio of 1.7, with 2.8% of women having died, compared with 4.7% of men.
Infection rates in womenand men

A side-by-side comparison of infection rates between the sexes does not explain the higher death rates in men, nor is there enough data available to draw a conclusion about infection rates broken down by sexes.

However, it is worth noting that in Denmark, where men are more than twice as likely to die of COVID-19 as women, the proportion of women who contracted the virus was 54%, while that of men was 46%.

By contrast, in Iran, where the ratio of deaths between men and women is less different (1.1 to 1), just 43% of cases are female compared with 57% cases in men.

Until we know the proportion of people from each sex that healthcare professionals are testing, it will be difficult to fully interpret these figures.

What we do know so far is that, overall, nine of the 18 countries that have provided complete sex-disaggregated data have more COVID-19 cases among women than they do among men. Six of the 18 countries have more cases among men than they do among women.

Norway, Sweden, and Germany have a 5050% case ratio.

Other countries where more women have developed COVID-19 include:
Switzerland (53% of women to 47% of men)Spain (51% to 49%)The Netherlands (53% to 47%)Belgium (55% to 45%)South Korea (60% to 40%)Portugal (57% to 43%)Canada (52% to 48%)Republic of Ireland (52% to 45%)

Greece, Italy, Peru, China, and Australia all have a higher number of confirmed cases among men than women.Why are men more likely to die?

Part of the explanation for why the new coronavirus seems to cause more severe illness in men is down to biological sex differences.

Womens innate immune response plays a role. Experts agree that there are sex differences, such as sex chromosomes and sex hormones, that influence how a persons immunity responds to a pathogen.

As a result, women are in general able to mount a more vigorous immune response to infections [and] vaccinations. With previous coronaviruses, specifically, some studies in mice have suggested that the hormone estrogen may have a protective role.

For instance, in the study above, the authors note that in male mice there was an exuberant but ineffective cytokine response. Cytokines are responsible for tissue damage within the lungs and leakage from pulmonary blood vessels.

Estrogens suppress the escalation phase of the immune response that leads to increased cytokine release. The authors showed that female mice treated with an estrogen receptor antagonist died at close to the same rate as the male mice.

As some researchers have noted, lifestyle factors, such as smoking and alcohol consumption, which tend to occur more among men, may also explain the overall higher mortality rates among men.

Science has long linked such behaviors with conditions that we now know are likely to negatively influence the outcome of patients with COVID-19 cardiovascular disease, hypertension, and chronic lung conditions. Why women might be more at risk

On the other hand, the fact that societies have traditionally placed women in the role of caregivers a role which they continue to fulfill predominantly and the fact that the vast majority of healthcare workers are women could place them at a higher risk of ontracting the virus and might explain the higher infection rates in some countries.

An analysis of 104 countries by the World Health Organization (WHO) found that Women represent around 70% of the health workforce. In China, women make up more than 90% of healthcare workers in Hubei province.

These data emphasize the gendered nature of the health workforce and the risk that predominantly female health workers incur, write the authors of a report on the gendered impacts of the pandemic that appears in The Lancet.

Although we cannot yet draw definitive conclusions because sex-disaggregated data is not yet available from all the countries affected, The Lancet report looks at previous epidemics for clues.

During the 201416 west African outbreak of Ebola virus disease, the authors write, gendered norms meant that women were more likely to be infected by the virus, given their predominant roles as caregivers within families and as frontline healthcare workers.

The authors also call out for governments and health institutions to offer and analyze data on sex and gender differences in the pandemic.
Why sex-disaggregated data are urgent

The report in The Lancet reads, Recognising the extent to which disease outbreaks affect women and men differently is a fundamental step to understanding the primary and secondary effects of a health emergency on different individuals and communities, and for creating effective, equitable policies and interventions.

For instance, identifying the key difference that makes women more resilient to the infection could help create drugs that also strengthen mens immune response to the virus.

Devising policies and intervention strategies that consider the needs of women who work as frontline healthcare workers could help prevent the higher infection rates that we see among women.

Finally, men and women tend to react differently to potential vaccines and treatments, so having access to sex-disaggregated data is crucial for conducting safe clinical trials.

As Anna Purdie who also works for Global Health 5050 and her colleagues summarize in their article, Sex-disaggregated data are essential for understanding the distributions of risk, infection, and disease in the population, and the extent to which sex and gender affect clinical outcomes.
Understanding sex and gender in relation to global health should not be seen as an optional add-on but as a core component of ensuring effective and equitable national and global health systems that work for everyone. National governments and global health organizations must urgently face up to this reality.

Anna Purdie et al

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NHL playoff watch: The Rangers’ path to the postseason

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NHL playoff watch: The Rangers' path to the postseason

Hockey fans often hear about the dreaded Stanley Cup hangover, when a team falters in the season after their championship. But a Presidents’ Trophy hangover?

Last season, the New York Rangers finished on top of the regular-season standings. This season, it’s looking less likely by the day that they’ll even make the playoffs.

When play begins Monday, the Rangers will be six points behind the Montreal Canadiens for the second wild-card spot in the Eastern Conference. With only six games left, they’ll need to come close to running the table, and will also need help from Montreal’s opponents.

Monday’s game is home against the Tampa Bay Lightning (7 p.m. ET, ESPN+). The Lightning have clinched a berth but will still be playing hard as they have a chance to catch the Toronto Maple Leafs for the top spot in the Atlantic Division.

After the Lightning, the Rangers host the Philadelphia Flyers, then have three straight road games, against the New York Islanders, Carolina Hurricanes and Florida Panthers. They close out the season with another matchup against the Lightning.

As noted, New York will need to gin up a winning streak here to bolster its chances. As for the Canadiens, they close out with a somewhat easier schedule: home against the Detroit Red Wings, at the Ottawa Senators and Maple Leafs, then home for the Chicago Blackhawks and the Hurricanes.

So that’s the task ahead for the Blueshirts. Will they come through?

With the regular season ending April 17, we’ll help you track it all with the NHL playoff watch. As we traverse the final stretch, we’ll provide details on all the playoff races, along with the teams jockeying for position in the 2025 NHL draft lottery.

Note: Playoff chances are via Stathletes.

Jump ahead:
Current playoff matchups
Clinching scenarios
Today’s schedule
Yesterday’s scores
Expanded standings
Race for No. 1 pick

Current playoff matchups

Eastern Conference

A1 Toronto Maple Leafs vs. WC1 Ottawa Senators
A2 Tampa Bay Lightning vs. A3 Florida Panthers
M1 Washington Capitals vs. WC2 Montreal Canadiens
M2 Carolina Hurricanes vs. M3 New Jersey Devils

Western Conference

C1 Winnipeg Jets vs. WC2 Minnesota Wild
C2 Dallas Stars vs. C3 Colorado Avalanche
P1 Vegas Golden Knights vs. WC1 St. Louis Blues
P2 Los Angeles Kings vs. P3 Edmonton Oilers


Clinching scenarios

The Edmonton Oilers will clinch a playoff spot if they defeat the Anaheim Ducks in any fashion, AND the Calgary Flames lose to the San Jose Sharks in regulation.

The St. Louis Blues will clinch a playoff spot if they defeat the Winnipeg Jets in regulation, AND the Flames lose to the Sharks in regulation.


Monday’s games

Note: All times ET. All games not on TNT or NHL Network are available to stream on ESPN+ (local blackout restrictions apply).

Tampa Bay Lightning at New York Rangers, 7 p.m.
St. Louis Blues at Winnipeg Jets, 7:30 p.m. (NHLN)
Edmonton Oilers at Anaheim Ducks, 10:30 p.m.
Seattle Kraken at Los Angeles Kings, 10:30 p.m.
Calgary Flames at San Jose Sharks, 10:30 p.m.


Sunday’s scoreboard

New York Islanders 4, Washington Capitals 1
Minnesota Wild 3, Dallas Stars 2 (OT)
Ottawa Senators 4, Columbus Blue Jackets 0
Detroit Red Wings 2, Florida Panthers 1
Buffalo Sabres 6, Boston Bruins 3
Chicago Blackhawks 3, Pittsburgh Penguins 1
Montreal Canadiens 2, Nashville Predators 1
Vegas Golden Knights 3, Vancouver Canucks 2


Expanded standings

Atlantic Division

Points: 98
Regulation wins: 39
Playoff position: A1
Games left: 6
Points pace: 105.7
Next game: @ FLA (Tuesday)
Playoff chances: 100%
Tragic number: N/A

Points: 94
Regulation wins: 38
Playoff position: A2
Games left: 6
Points pace: 101.4
Next game: @ NYR (Monday)
Playoff chances: 100%
Tragic number: N/A

Points: 92
Regulation wins: 35
Playoff position: A3
Games left: 5
Points pace: 98.0
Next game: vs. TOR (Tuesday)
Playoff chances: 100%
Tragic number: N/A

Points: 90
Regulation wins: 33
Playoff position: WC1
Games left: 5
Points pace: 95.8
Next game: @ CBJ (Tuesday)
Playoff chances: 99.9%
Tragic number: N/A

Points: 85
Regulation wins: 28
Playoff position: WC2
Games left: 5
Points pace: 90.5
Next game: vs. DET (Tuesday)
Playoff chances: 79.2%
Tragic number: N/A

Points: 79
Regulation wins: 28
Playoff position: N/A
Games left: 6
Points pace: 85.2
Next game: @ MTL (Tuesday)
Playoff chances: 5.4%
Tragic number: 6

Points: 74
Regulation wins: 27
Playoff position: N/A
Games left: 6
Points pace: 79.8
Next game: vs. CAR (Tuesday)
Playoff chances: 0.1%
Tragic number: 1

Points: 71
Regulation wins: 24
Playoff position: N/A
Games left: 4
Points pace: 74.6
Next game: @ NJ (Tuesday)
Playoff chances: 0%
Tragic number: E


Metro Division

Points: 107
Regulation wins: 42
Playoff position: M1
Games left: 5
Points pace: 114.0
Next game: vs. CAR (Thursday)
Playoff chances: 100%
Tragic number: N/A

Points: 96
Regulation wins: 41
Playoff position: M2
Games left: 6
Points pace: 103.6
Next game: @ BUF (Tuesday)
Playoff chances: 100%
Tragic number: N/A

Points: 89
Regulation wins: 36
Playoff position: M3
Games left: 5
Points pace: 94.8
Next game: vs. BOS (Tuesday)
Playoff chances: 99.9%
Tragic number: N/A

Points: 79
Regulation wins: 32
Playoff position: N/A
Games left: 6
Points pace: 85.2
Next game: vs. TB (Monday)
Playoff chances: 8.5%
Tragic number: 6

Points: 78
Regulation wins: 27
Playoff position: N/A
Games left: 6
Points pace: 84.2
Next game: @ NSH (Tuesday)
Playoff chances: 2.5%
Tragic number: 5

Points: 77
Regulation wins: 24
Playoff position: N/A
Games left: 6
Points pace: 83.1
Next game: vs. OTT (Tuesday)
Playoff chances: 4.5%
Tragic number: 4

Points: 74
Regulation wins: 21
Playoff position: N/A
Games left: 4
Points pace: 77.8
Next game: vs. CHI (Tuesday)
Playoff chances: 0%
Tragic number: E

Points: 71
Regulation wins: 20
Playoff position: N/A
Games left: 5
Points pace: 75.6
Next game: @ NYR (Wednesday)
Playoff chances: 0%
Tragic number: E


Central Division

Points: 108
Regulation wins: 41
Playoff position: C1
Games left: 5
Points pace: 115.0
Next game: vs. STL (Monday)
Playoff chances: 100%
Tragic number: N/A

Points: 105
Regulation wins: 41
Playoff position: C2
Games left: 5
Points pace: 111.8
Next game: vs. VAN (Tuesday)
Playoff chances: 100%
Tragic number: N/A

Points: 98
Regulation wins: 39
Playoff position: C3
Games left: 4
Points pace: 103.0
Next game: vs. VGK (Tuesday)
Playoff chances: 100%
Tragic number: N/A

Points: 93
Regulation wins: 31
Playoff position: WC1
Games left: 4
Points pace: 97.8
Next game: @ ANA (Monday)
Playoff chances: 99.5%
Tragic number: N/A

Points: 91
Regulation wins: 33
Playoff position: WC2
Games left: 4
Points pace: 95.7
Next game: vs. SJ (Wednesday)
Playoff chances: 86.4%
Tragic number: N/A

Points: 82
Regulation wins: 27
Playoff position: N/A
Games left: 5
Points pace: 87.3
Next game: vs. SEA (Tuesday)
Playoff chances: 0.2%
Tragic number: 1

Points: 62
Regulation wins: 23
Playoff position: N/A
Games left: 5
Points pace: 66.0
Next game: vs. NYI (Tuesday)
Playoff chances: 0%
Tragic number: E

Points: 54
Regulation wins: 19
Playoff position: N/A
Games left: 5
Points pace: 57.5
Next game: @ PIT (Tuesday)
Playoff chances: 0%
Tragic number: E


Pacific Division

Points: 102
Regulation wins: 43
Playoff position: P1
Games left: 5
Points pace: 108.6
Next game: @ COL (Tuesday)
Playoff chances: 100%
Tragic number: N/A

Points: 97
Regulation wins: 39
Playoff position: P3
Games left: 6
Points pace: 104.7
Next game: vs. SEA (Monday)
Playoff chances: 100%
Tragic number: N/A

Points: 93
Regulation wins: 32
Playoff position: P2
Games left: 6
Points pace: 100.3
Next game: @ ANA (Monday)
Playoff chances: 99.9%
Tragic number: N/A

Points: 85
Regulation wins: 27
Playoff position: N/A
Games left: 6
Points pace: 91.7
Next game: @ SJ (Monday)
Playoff chances: 12.6%
Tragic number: 6

Points: 83
Regulation wins: 27
Playoff position: N/A
Games left: 5
Points pace: 88.4
Next game: @ DAL (Tuesday)
Playoff chances: 1.4%
Tragic number: 2

Points: 74
Regulation wins: 23
Playoff position: N/A
Games left: 6
Points pace: 79.8
Next game: vs. EDM (Monday)
Playoff chances: 0%
Tragic number: E

Points: 72
Regulation wins: 27
Playoff position: N/A
Games left: 5
Points pace: 76.7
Next game: @ LA (Monday)
Playoff chances: 0%
Tragic number: E

Points: 50
Regulation wins: 14
Playoff position: N/A
Games left: 6
Points pace: 54.0
Next game: vs. CGY (Monday)
Playoff chances: 0%
Tragic number: E

Note: An “x” means that the team has clinched a playoff berth. An “e” means that the team has been eliminated from playoff contention.


Race for the No. 1 pick

The NHL uses a draft lottery to determine the order of the first round, so the team that finishes in last place is not guaranteed the No. 1 selection. As of 2021, a team can move up a maximum of 10 spots if it wins the lottery, so only 11 teams are eligible for the No. 1 pick. Full details on the process are here. Matthew Schaefer, a defenseman for the OHL’s Erie Otters, is No. 1 on the draft board.

Points: 50
Regulation wins: 14

Points: 54
Regulation wins: 19

Points: 62
Regulation wins: 23

Points: 71
Regulation wins: 20

Points: 71
Regulation wins: 24

Points: 72
Regulation wins: 27

Points: 74
Regulation wins: 21

Points: 74
Regulation wins: 23

Points: 74
Regulation wins: 27

Points: 77
Regulation wins: 24

Points: 78
Regulation wins: 27

Points: 79
Regulation wins: 28

Points: 79
Regulation wins: 32

Points: 82
Regulation wins: 27

Points: 83
Regulation wins: 27

Points: 85
Regulation wins: 27

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Utah HC to open new training facility in Sept.

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Utah HC to open new training facility in Sept.

The Utah Hockey Club will open a new practice and training facility for team use on Sept. 1, the team announced Monday.

The 115,780-square-foot facility, built on the southeastern end of a Sandy shopping mall, will house two NHL standard ice sheets. It will also include training, medical and dining facilities as well as team locker rooms.

Building a practice facility quickly was one of the immediate challenges Utah owner Ryan Smith faced in bringing an NHL team to the Beehive State. The Utah Olympic Oval, which is primarily used for speedskating events, served as the team’s practice facility this season, but it was intended to be only a temporary solution.

“We want to be competitive in the NHL, and to do that you got to have a place where these guys can practice and they can recover, and it’s home,” Smith said. “We did a miraculous job with the Oval, but at the same time that’s not this.”

Players on Utah’s roster had input on the practice facility’s design from the dining areas to the locker rooms. The facility incorporates many of their suggestions.

“We tried to involve them as much as we can in every part of this,” Smith said.

Utah’s practice facility will also be ready for public use next January. It will feature event venues, eight community locker rooms, equipment rentals and a team store. The ice rinks will be available to the public when not in use by the team.

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Putin congratulates Ovechkin on breaking record

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Putin congratulates Ovechkin on breaking record

MOSCOW — Russian President Vladimir Putin has congratulated Alex Ovechkin for setting an “outstanding record” as the NHL’s top career goal scorer.

In a message after Ovechkin’s 895th career goal broke a tie for the record with Wayne Gretzky in the Washington Capitals‘ game Sunday against the New York Islanders, Putin said the achievement was something Russians would celebrate.

“I congratulate you on your outstanding record. You have surpassed legendary masters in the number of goals scored in National Hockey League regular-season games,” Putin said in a statement released by the Kremlin on Monday.

Breaking Gretzky’s record “has become not only your personal success, but also a real celebration for fans in Russia and abroad,” Putin added. “I wish you health, good fortune [and] fighting spirit to conquer new heights in life and in sports.”

Kremlin spokesperson Dmitry Peskov said Monday that Putin and Ovechkin had not yet spoken by phone but that Putin’s message of congratulations showed the president “highly values Ovechkin’s sporting result.”

Ovechkin has been a backer of Putin in the past and in 2017 set up a group called Putin Team on social media to show support for the Russian president, who was reelected the following year.

At the time, Ovechkin told The Associated Press and The Washington Post, “I just support my country,” and said, “It’s not about political stuff.”

Russian Sports Minister Mikhail Degtyarev referred to that moment in his own statement of congratulations after Ovechkin broke the record Sunday.

He posted on social media that Ovechkin “remains a member of the Putin team and at the same time one of the main faces of world hockey, a favorite of millions and the NHL top scorer.”

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