Connect with us

Published

on

A cure for motor neurone disease (MND) could be “possible”, according to an expert, as a charity launched by a rugby legend unveils its five-year research strategy to give hope to those diagnosed with the condition.

The My Name’5 Doddie Foundation (MNDF), first set up in 2017 by the late Scottish rugby player Doddie Weir, will invest millions of pounds into research for treatments.

Mr Weir died in November 2022, following a six-year-long battle with MND.

The charity’s aim will be to effectively deliver treatments to slow the progress of MND, while also working towards the goal of finding a complete cure.

And Professor Ammar Al-Chalabi, director of the MND Research Centre at King’s College London, said finding a cure is now a real possibility.

He said: “When I started MND research almost 30 years ago it seemed ridiculous that an effective treatment might be possible.

“Now a cure is a possibility, although a treatment that dramatically slows MND is more likely. Both are still somewhat in the future.”

The money provided by charities is vital to driving research into treatments and an eventual cure, the professor added.

He said: “Research is expensive, however, and My Name’5 Doddie Foundation and other MND charities are crucial in funding it.

“They drive the cutting-edge stuff that pushes the field forward as well as the important ‘slogging away at it’ work that is essential to keep everything going.

“We are only where we are because of MND charities and the people who fundraise so effectively.”

Effective treatments ‘aren’t too far away’

Doddie Weir was inspired to set up a charity because a diagnosis of MND seemed to be without hope.

MNDF’s new five-year strategy, known as the Catalysis a Cure strategy, aims to drive forward research over the next five years with a commitment by 2028 to have invested in developing new treatments and improving early diagnosis.

It will also improve biomarkers which indicate whether treatments are working or not.

The organisation has committed around £8.5m to research and was also one of several UK organisations to successfully campaign for a UK government commitment of £50m for MND research.

Jessica Lee, director of research at MNDF, said: “We believe that effective treatments to slow or stop disease progression aren’t too far away.

“By working closely with our remarkable research community and supporting the adoption of new approaches and ways of thinking, we will accelerate the journey towards making these treatments a reality.”

Sports broadcaster and chief executive of the charity, Jill Douglas, added: “Doddie’s greatest frustration when he was diagnosed with MND in 2016 was the lack of hope for people faced with such devastating news.

“He wanted the Foundation to relentlessly work towards a world where that is not the case, and we are beginning to see real progress.

“There is huge momentum in MND research, and backed by the thousands of fundraisers who support the Foundation, this bold and ambitious research strategy ensures we are in the best position possible to build on that and work with the MND research community to hopefully accelerate the development of new treatments.”

Read more:
‘Important new step’ in finding treatment, scientists reveal
‘Milestone’ treatment slows weakness – study

What is motor neurone disease?

According to the NHS, motor neurone disease (MND) is an uncommon condition affecting the brain and nerves – it can also cause weakness and gradually worsen over time.

The condition mainly affects people in their 60s and 70s but can also affect adults of all ages.

There is no cure as of yet, but there are treatments to help reduce the impact it has on someone’s day-to-day life.

Some people can live with the condition for many years but it can also be fatal.

The NHS says MND can happen gradually and may not be obvious initially. Here are some of the early symptoms:

• Weakness in ankle or leg, leading to difficulty climbing stairs

• Slurred speech, which may develop into difficulty swallowing some foods

• A weak grip

• Muscle cramps and twitches

• Weight loss

• Difficulty stopping yourself from crying or laughing in inappropriate situations

Continue Reading

UK

PPE Medpro partners open to settlement over £122m COVID gowns contract breach

Published

on

By

PPE Medpro partners open to settlement over £122m COVID gowns contract breach

Partners of a company linked to Baroness Michelle Mone have said they are open to a possible settlement with the government after the company was found to have breached a £122m PPE contract.

The Department of Health and Social Care (DHSC) had accused PPE Medpro of providing 25 million “faulty”, non-sterile gowns during the COVID pandemic.

The High Court ruled earlier this month that it must pay back a £121.9m sum, the price of the gowns.

PPE Medpro, a consortium led by Lady Mone‘s husband Doug Barrowman, filed to enter administration earlier this month.

In a statement on Friday, Mr Barrowman said: “The consortium partners of PPE Medpro are prepared to enter into a dialogue with the administrators of the company to discuss a possible settlement with the government.”

PPE Medpro has spent £4.3m defending its position.

It said offers to settle on a no-fault basis had been made, including the remake of 25 million gowns, or a £23m cash equivalent, which were rejected.

More on Michelle Mone

Please use Chrome browser for a more accessible video player

Sky’s Paul Kelso analyses scandal surrounding Baroness Mone

The consortium was awarded government contracts by the former Conservative administration to supply personal protective equipment (PPE) during the pandemic after Lady Mone recommended it to ministers.

It insists that it provided all 25 million gowns and disputes that the gowns were not sterile.

It is understood the partners want to resolve the issue, and administrators have been urged to approach the government to reach an agreement.

Please use Chrome browser for a more accessible video player

Reeves welcomes ruling on PPE contract breach

Read more:
Can PPE Medpro afford to pay back govt?

Baroness Mone: I have no wish to rejoin Lords
Baroness Mone ‘should resign’ from Lords

In the High Court ruling, Mrs Justice Cockerill said the gowns “were not, contractually speaking, sterile, or properly validated as being sterile”. This meant they could not be used in the NHS.

Barristers for PPE Medro claimed it had been “singled out for unfair treatment” and accused the government of “buyer’s remorse”.

Michelle Mone recommended the firm, led by husband Doug Barrowman, to minsters. Pic: PA
Image:
Michelle Mone recommended the firm, led by husband Doug Barrowman, to minsters. Pic: PA

It claimed the gowns had become defective because of the conditions they were kept in after being delivered. It also said the court made its ruling on a technicality.

Lady Mone branded the judgement a win for the “establishment”, while Mr Barrowman said it was a “travesty of justice”.

Baroness Mone, who created the lingerie brand Ultimo, was made a Conservative peer in 2015.

She now says she has “no wish to return” to the House of Lords.

Continue Reading

UK

Women risking breast cancer by ‘always putting ourselves last’, says Liz Hurley

Published

on

By

Women risking breast cancer by 'always putting ourselves last', says Liz Hurley

Liz Hurley has encouraged women to check themselves for breast cancer – and warned some are not because they “are scared that it’s self-indulgent to spend time on themselves”.

The British actress and model, who has been a global ambassador for the Estee Lauder Companies’ Breast Cancer Campaign for 30 years, told Sky News’ Jacquie Beltrao the demands of everyday life mean women “always put ourselves last”.

“We’re doing stuff for kids, for husbands, for mothers, for in-laws. There’s so much that we have to do that we tend to come last,” she said.

Hurley, whose grandmother died of breast cancer, said she finds it helps by thinking of breast checks as a way to “keep ourselves healthy in order to continue to take care of everybody else”.

That way, it “doesn’t seem self-indulgent or taking time away from something else, it seems really important”.

Checking one’s breasts “takes two minutes”, she added, or “about the same length of time as brushing your teeth”.

Hurley speaking to Sky's Jacquie Beltrao
Image:
Hurley speaking to Sky’s Jacquie Beltrao

More than a third of women in the UK do not take up the first mammogram appointment they are offered, and a recent study of 500,000 women from Sweden found a similar non-attendance rate there.

More on Cancer

More than 11,000 people die from breast cancer every year in the UK, or 31 each day, Cancer Research UK said.

That makes it the second most common form of cancer death, accounting for 7% of all cancer deaths, the charity said.

Asked whether some of the messaging had “fallen on deaf ears”, Hurley said attending screenings, which are free on the NHS, is “definitely advised”, and she suggested all women should familiarise themselves with their breasts.

In the past, the illness was seen as “a disease for older ladies. And we didn’t understand that younger women also get diagnosed. That’s been a lot in the news lately”, Hurley said.

“There appear to be more women, younger women being diagnosed. And that could well be one of the reasons is that people are more breast aware, more self-aware.”

Read more on Sky News:
Men must ‘demand cancer test’
Warning of millions of new cancer cases

She told Ms Beltrao, who is a breast cancer survivor, people “have seen you on television talking about breast cancer”.

As a result of more awareness, she said, women have “begun to understand that it can never be too early to start checking your own breasts and to familiarise yourself [with them].

“When you’re younger and you’re not yet having regular mammograms, you do really have to be aware of your own breasts to be able to see if there’s a change, feel if there is a change and go to your doctor.”

Continue Reading

UK

‘New era’ for British passports as King’s coat of arms appears on cover 

Published

on

By

'New era' for British passports as King's coat of arms appears on cover 

The King’s coat of arms will be on the front of all new British passports from December, the Home Office has announced. 

The inside pages have also been updated to include images of natural landscapes from all four UK nations, including Ben Nevis, the Lake District, Three Cliffs Bay, and the Giant’s Causeway.

The Home Office said the new passport is the first wholly new design in five years, and it will be the “most secure passport ever produced”.

It will include the latest anti-forgery technology, including new holographic and translucent features.

The updated features will improve verification and make passports significantly more resistant to forgery or tampering, the Home Office said.

The bio page of the new UK passport. Pic: PA
Image:
The bio page of the new UK passport. Pic: PA

Migration and citizenship minister Mike Tapp said: “The introduction of His Majesty’s arms, iconic landscapes, and enhanced security features marks a new era in the history of the British passport.

“It also demonstrates our commitment to outstanding public service – celebrating British heritage while ensuring our passports remain among the most secure and trusted in the world for years to come.”

More from UK

The Home Office has confirmed that passports bearing Queen Elizabeth II‘s coat of arms will remain valid until their printed expiry date.

Read more from Sky News:
Liam Gallagher among stars at Ricky Hatton funeral
Migrant with AK-47 tattoo found guilty of threatening to kill Farage

However, it advised travellers to check their passports’ validity and renew them well in advance of any upcoming trips.

The first modern British passport was introduced over a hundred years ago, in 1915.

Continue Reading

Trending