Medicinal cannabis helps relieve cancer pain and can complement other painkilling drugs, research has suggested.
A study of 358 adults with cancer found that an equal balance of active ingredients tetrahydrocannabinol (THC) and cannabidiol (CBD), significantly helped pain intensity and the interference of pain in daily life.
THC is the substance in cannabis that is primarily responsible for producing the ‘high’ sensation.
Researchers from the Royal College of Surgeons, Dublin, and the Medical Cannabis Programme in Oncology at Cedars Cancer Centre in Canada, concluded that medicinal cannabis is “a safe and effective complementary treatment for pain relief in patients with cancer”.
Currently, only specialist doctors can prescribe cannabis-based medicines on the NHS, and only for a few limited conditions such as rare and severe epilepsy.
Existing evidence suggests that around 38% of all patients with cancer experience moderate to severe pain, while 66% with advanced, metastatic or terminal diseases suffer pain.
Of those studied, around a quarter took THC-dominant products, 38% took THC:CBD-balanced drugs and 17% took CBD-dominant products.
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Patient pain intensity, symptoms, total number of drugs taken and daily morphine consumption were then closely monitored by healthcare professionals, quarterly for a year.
At three, six and nine months, THC:CBD-balanced products were associated with the best pain relief.
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“Our data suggest a role for medicinal cannabis as a safe and complementary treatment option in patients with cancer failing to reach adequate pain relief through conventional analgesics, such as opioids,” researchers said.
The results come as a clinical trial of an oral spray containing cannabis, to treat the most aggressive type of brain tumour – glioblastoma – has opened at Leeds Teaching Hospitals NHS Trust and the Christie NHS Foundation Trust in Manchester.
Medical cannabis was legalised in the UK in 2018, families have since urged the governmentand Health Secretary, Steve Barclay, to fund more research.
A woman whose body was found in the boot of a car last week died from strangulation, according to a post-mortem examination.
A manhunt is under way for Harshita Brella’s husband, Pankaj Lamba, who police believe has fled the country.
Officers said today that her body was discovered in a silver Vauxhall Corsa.
They believe she was killed on the evening of Sunday 10 November and driven in the early hours from the couple’s home in Corby, Northamptonshire, to Ilford in east London.
It’s understoodthe 24-year-old had been under the protection of a court order for victims of domestic abuse.
Northamptonshire Police said officers began searching for her after receiving a call with concerns for her welfare on 13 November – the day before she was found dead.
A post-mortem examination found Ms Brella’s preliminary cause of death was strangulation, police said.
New CCTV images of Pankaj Lamba, 23, have also been released as the manhunt continues.
Detective Chief Inspector Johnny Campbell, from the East Midlands major crime unit, said: “We suspect Harshita’s body had been placed in the boot of the vehicle by Lamba before leaving Corby.
“Lamba then abandoned the vehicle in Brisbane Road, Ilford, and made his getaway.”
Northamptonshire Police, the East Midlands major crime unit and the National Crime Agency are working together to try to find him.
An inquest into Ms Brella’s death will be opened on 20 November at The Guildhall in Northampton.
Anyone who thinks they might have seen Pankaj Lamba is urged to make contact as soon as possible.
“Any information, no matter how small, may be relevant to the investigation and help us get justice for Harshita,” said DCI Campbell.
People with relevant information can call 101, Crimestoppers anonymously on 0800 555111, or online at mipp.police.uk
She said she was leaving to focus on family, but will remain part of the Radio 2 team and will give further details next year.
Announcing the news on her Tuesday show, she said: “After six years of fun times alongside you all on the breakfast show, I’ve decided it’s time to step away from the early alarm call and start a new chapter.
“You know I think the world of you all, listeners, and it truly has been such a privilege to share the mornings with you, to go through life’s little ups and downs, we got through the lockdown together, didn’t we?
“We’ve shared a hell of a lot, the good times, the tough times, there’s been a lot of laughter. And I am going to miss you cats.”
Scott Mills will replace Ball on the breakfast show following her departure next month.
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“Zoe and I have been such good friends now for over 25 years and have spent much of that time as part of the same radio family here at Radio 2 and also on Radio 1,” he said.
“She’s done an incredible job on this show over the past six years, and I am beyond excited to be handed the baton.”
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Hugging outside the BBC building on the day of the announcement, Ball said she was “really chuffed for my mate and really excited about it”.
Ball was the first female host of both the BBC Radio 1 and Radio 2 breakfast shows, starting at the Radio 1 breakfast show in 1998, and taking over her current Radio 2 role from Chris Evans in 2020 after he left the show.
She took a break from hosting her show over the summer, returning in September.
Ahead of her stint in radio, Ball – who is the daughter of children’s presenter Johnny Ball – co-hosted the BBC’s Saturday morning children’s magazine show Live & Kicking alongside Jamie Theakston for three years from 1996.
She has two children, Woody and Nelly, with her ex-husband, DJ and musician Norman Cook, known professionally as Fatboy Slim.
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Ball said in her announcement her last show towards the end of December will be “just in time for Christmas with plenty of fun and shenanigans”.
“While I’m stepping away from the Breakfast Show, I’m not disappearing entirely – I’ll still be a part of the Radio 2 family, with more news in the New Year,” she added.
“I’m excited to embrace my next chapter, including being a mum in the mornings, and I can’t wait to tune in on the school run!”
Helen Thomas, head of Radio 2, said: “Zoe has woken up the nation on Radio 2 with incredible warmth, wit and so much joy since January 2019, and I’d like to thank her for approaching each show with as much vim and vigour as if it were her first. I’m thrilled that she’ll remain an important part of the Radio 2 family.”
Mills, 51, got his first presenting role aged just 16 for a local station in Hampshire, and went on to present in Bristol and Manchester, before joining BBC Radio 1 in 1998.
He’s previously worked as a cover presenter on Radio 2, but this is his first permanent role on the station.