Connect with us

Published

on

For the first time, doctors surgically repaired a malformed blood vessel in a baby’s brain while she was still in the womb. The baby, born in mid-March, was discharged from the hospital a few weeks after birth and has not required any medications or other treatments since then.

“I heard her cry for the first time and that just, I — I can’t even put into words how I felt at that moment,” Kenyatta Coleman of Baton Rouge, Louisiana, the baby’s mother, told CNN (opens in new tab) . “It was just, you know, the most beautiful moment being able to hold her, gaze up on her and then hear her cry.”

In a new report, published Thursday (May 4) in the journal Stroke (opens in new tab) , doctors described the first-of-its-kind procedure, which was conducted as part of an ongoing clinical trial (opens in new tab) . The trial is aimed at finding a new way to treat vein of Galen malformation (opens in new tab) (VOGM), a rare abnormality that affects the blood vessels that carry oxygenated blood from the heart to the brain. 

In VOGM, certain arteries in the brain don’t link to capillaries — delicate, branching blood vessels that help slow blood flow — as they normally would. Instead, the arteries dump blood into veins at the base of the brain, and this blood flows at a high pressure. The high-pressure blood flow can cause congestive heart failure, high blood pressure in the arteries of the lungs (pulmonary hypertension), brain tissue injury and loss, or an enlarged head (hydrocephalus).

Related: In a 1st, baby’s heart defect successfully treated with injected stem cells 

VOGM affects an estimated 1 in 60,000 births, according to a statement from the American Heart Association (opens in new tab) (AHA). The standard treatment takes place after birth and involves blocking off the artery-to-vein connections within the malformation. However, this procedure can’t always reverse the onset of heart failure, and it can be too late to prevent disabling or life-threatening brain damage.

Doctors from Boston Children’s Hospital and the Brigham and Women’s Hospital in Boston launched a trial to treat VOGM sooner, while the fetus is still in the womb. The new approach uses an in utero surgery designed to reduce the aggressive blood flow through the VOGM. The trial will include an estimated 20 babies, in total, and the recently treated baby, Denver Coleman, was the first to undergo the procedure.RELATED STORIES—Mini-brains show how common drug freezes cell division in the womb, causing birth defects

—Father’s use of diabetes drug could raise his kids’ risk of birth defects

—Having a baby: Stages of pregnancy by trimester

“In our first treated case, we were thrilled to see that the aggressive decline usually seen after birth simply did not appear,” Dr. Darren Orbach (opens in new tab) , co-director of the Cerebrovascular Surgery & Interventions Center at Boston Children’s Hospital, an associate professor of radiology at Harvard Medical School and lead author of the case report, said in the AHA statement.

“We are pleased to report that at six weeks, the infant is progressing remarkably well, on no medications, eating normally, gaining weight and is back home,” Orbach said. “There are no signs of any negative effects on the brain.”

Denver and Kenyatta Coleman underwent the “transuterine” procedure 34 weeks and two days into the pregnancy. (The VOGM was diagnosed just after an ultrasound at 30 weeks, according to CNN.) 

Following the procedure, Kenyatta Coleman began leaking amniotic fluid,  meaning her “water had begun to break,” so doctors delivered the baby by induction of vaginal birth two days later. The newborn did not require any cardiovascular support or surgery after birth but was monitored in the neonatal intensive care unit for several weeks before discharge.

“While this is only our first treated patient and it is vital that we continue the trial to assess the safety and efficacy in other patients,” Orbach said, “this approach has the potential to mark a paradigm shift in managing vein of Galen malformation where we repair the malformation prior to birth and head off the heart failure before it occurs, rather than trying to reverse it after birth.”

Continue Reading

Sports

Cindric docked points, fined for spinning Dillon

Published

on

By

Cindric docked points, fined for spinning Dillon

CHARLOTTE, N.C. — Austin Cindric was docked 50 points and fined $50,000 by NASCAR on Wednesday for intentionally spinning Ty Dillon in last weekend’s Cup Series race at Circuit of the Americas.

Dillon moved Cindric up the track early in the race and Cindric quickly retaliated by hooking Dillon in the right rear, spinning Dillon’s car.

NASCAR has made clear they will not tolerate drivers hooking competitors in the right rear to spin them because of the potential hazards. Bubba Wallace and Chase Elliott have both previously been suspended for similar actions.

The penalty drops Cindric of Team Penske from 11th to 35th in the standings heading into this weekend’s race at Phoenix Raceway.

NASCAR fined Carson Hocevar $50,000 and penalized him 25 points for intentionally wrecking Harrison Burton last year. Hocevar hooked Burton in the right rear while under caution at Nashville Superspeedway.

One of the reasons Cindric was not suspended, per a NASCAR official, is because it happened on a road course with lower speeds and tight confines — and the result didn’t draw a caution flag.

Wallace and Elliott both hooked other drivers on ovals with higher speeds that led to cautions.

In additional penalties announced Wednesday, NASCAR said two members of Kyle Larson‘s pit crew had been suspended two races for a tire coming off his car during last weekend’s Cup race at COTA. Brandon Johnson, the jackman, and front tire changer Blaine Anderson were both suspended.

Continue Reading

Sports

Briscoe wins appeal over spoiler at Daytona 500

Published

on

By

Briscoe wins appeal over spoiler at Daytona 500

CHARLOTTE, N.C. — Chase Briscoe and Joe Gibbs Racing won their appeal Wednesday when the National Motorsports Appeals Panel said his Toyota did not have an illegally modified spoiler when he won the Daytona 500 pole.

The victory restores the 100 points and 10 playoff points NASCAR had penalized Briscoe for the spoiler violation. The team also gets its 100 points and 10 playoff points back, and crew chief James Small’s four-race suspension was rescinded, as was the $100,000 fine to the team.

Briscoe is now tied for 14th in the season standings with Carson Hocevar headed into Sunday’s race at Phoenix Raceway. They are one point ahead of Kyle Larson, who is 16th in the season standings.

“The panel believes that the elongation of some of the holes on the number 19 Cup car spoiler base is caused by the process of attaching that specific spoiler base to the rear deck and not modification of the single source part,” the panel wrote.

Joe Gibbs said he was appreciative of the process “NASCAR has in place that allowed us the opportunity to present our explanation of what led to the penalty issued to our No. 19 team.

“We are thankful for the consideration and ruling by the National Motorsports Appeals Panel,” the team owner added. “It is obviously great news for our 19 team and everyone at Joe Gibbs Racing. We look forward to focusing on the remainder of our season starting this weekend in Phoenix.”

Briscoe also thanked the panel and NASCAR on social media “for giving us the option to show our evidence.” He also thanked Joe Gibbs Racing for preparing his car for his debut season with the team.

The appeals panel consisted of former motorsports marketing executive Dixon Johnston, former Speed Channel president Hunter Nickell and former South Boston Speedway general manager Cathy Rice.

Continue Reading

Sports

NASCAR countersues in dispute over charters

Published

on

By

NASCAR countersues in dispute over charters

CHARLOTTE, N.C. — NASCAR’s revenue-sharing charter system is under threat of being disbanded according to a Wednesday counterclaim filed by the stock car series against Michael Jordan-owned 23XI Racing and Front Row Motorsports that singles out Jordan’s longtime business manager.

The contentiousness began after more than two years of negotiations on new charter agreements — NASCAR’s equivalent of a franchise model — and the 30-page filing contends that Jordan business manager Curtis Polk “willfully” violated antitrust laws by orchestrating anticompetitive collective conduct in connection with the most recent charter agreements.

23XI and Front Row were the only two organizations out of 15 that refused to sign the new agreements, which were presented to the teams last September in a take-it-or-leave-it offer a mere 48 hours before the start of NASCAR’s playoffs.

The charters were fought for by the teams ahead of the 2016 season and twice have been extended. The latest extension is for seven years to match the current media rights deal and guarantee 36 of the 40 spots in each week’s field to the teams that hold them, as well as other financial incentives. 23XI and Front Row refused to sign and sued, alleging NASCAR and the France family that owns the stock car series are a monopoly.

NASCAR already has lost one round in court in which the two teams have been recognized as chartered organizations for the 2025 season as the legal dispute winds through the courts.

What is NASCAR counterclaiming?

In the new counterclaim, Polk is repeatedly singled out as the ringleader against the current charter proposals. NASCAR attorney Christopher Yates went so far as to tell The Associated Press that Polk, who in addition to being Jordan’s business manager is a co-owner of 23XI along with three-time Daytona 500 winner Denny Hamlin, does not understand the NASCAR business model.

“Curtis Polk basically orchestrated and threatened a boycott of one of the qualifying races for a major event and others did not go along with him,” Yates said. “He got other teams to boycott a meeting that was required by the charter. When you have a threatened boycott of qualifying races that are covered by media that’s not a good thing for other race teams, not a good thing when you are trying to collectively grow the sport.”

The qualifying race in question was the 2024 pair of 150-mile duels that set the field for the Daytona 500.

“I don’t think Mr. Polk really understands the sport,” Yates told the AP. “I think he came into it and his view is it should be much more like the NBA or other league sports. But it’s not. No motorsport is like that. He’s done a lot of things that might work in the NBA or might be OK in the NBA but just are not appropriate in NASCAR.”

Who is violating the antitrust act?

NASCAR’s complaint alleges “the undisputed reality is that it is 23XI and FRM, led by 23XI’s owner and sports agent Curtis Polk, that willfully violated the antitrust laws by orchestrating anticompetitive collective conduct in connection with the terms of the 2025 Charter Agreements.”

“It is truly ironic that in trying to blow-up the Charter system, 23XI and FRM have sought to weaponize the antitrust laws to achieve their goals,” the counterclaim says, alleging Polk’s threats are “attempting to misuse the legal system as a last resort to secure new terms.”

Bob Jenkins, an entrepreneur, owns Front Row Motorsports and joined 23XI in the lawsuit when he declined to sign the 2025 charter agreement last September.

NASCAR’s counterclaim asks for an injunction eliminating guaranteed starting spots for charter teams. NASCAR wants the four combined charters held by 23XI and Front Row before the lawsuit to be returned to NASCAR, and it wants to dissolve the two charters each team purchased ahead of the 2025 season for their own individual expansion.

“There’s a misperception out there that somehow 23IX and Front Row might achieve something that other teams can take advantage of, and that’s just not right,” Yates told the AP. “This is not going to be a renegotiation. NASCAR has no intent of renegotiating the terms of the charter. Front Row and 23XI are threatening the charter system and its continuation, and NASCAR is fine without the charter system.

“The charter system was created at the request of the teams. That was before 23XI and Curtis Polk’s time, I don’t think they understand that history. But if they succeed with their lawsuit and the charter system goes away, that’s OK.”

What do 23XI and Front Row want?

Yates told the AP he’s asked Jeffrey Kessler, the attorney representing 23XI and Front Row, what is it the two teams want and cannot get a straight answer.

“The mere fact that the lawsuit calls the system into question, I really think 23XI and Front Row are being pretty selfish in terms of what they are trying to do, and I don’t think they are taking into account the 32 teams that have signed the charters and think it is a good deal for them,” Yates said. “Do some of them think they should have gotten more? I’m sure. Does NASCAR think it should have gotten more? Absolutely. But NASCAR does not see the charter system as necessary.”

Jordan has said he’s suing NASCAR on behalf of all the teams so that even the smallest ones can receive equal footing in terms of benefits as a participant in the top motorsports league in the United States.

Among the improvements in the 2025 charters is a more equitable revenue share, but missing is the demand that teams wanted the charters to become permanent. NASCAR at its discretion can claw back charters from underperforming teams or eliminate the system completely. Yates said NASCAR has no intention of renegotiating the charters signed in September by 13 organizations, nor did he see a scenario in which NASCAR settles the lawsuit.

“Polk and 23XI’s other owners openly professed that they wanted to change NASCAR’s economic model by demanding more money for the teams from NASCAR media revenues, instead of teams competing against each other,” Yates said. “However, 23XI and FRM did not merely reject the terms of the 2025 Charters. Rather, those teams embarked on a strategy to threaten, coerce, and extort NASCAR into meeting their demands for better contract and financial terms.”

Continue Reading

Trending