First cases of treatment-resistant ringworm found in patients in US
Two cases of highly contagious, drug-resistant ringworm infection have been detected in the US.
The cases were reported to the Centers for Disease Control and Prevention (CDC) in February and shared in a report published on Thursday.
The patients, from New York City, had their first symptoms in 2021 and 2022.
One of the patients carrying the infection was identified as a 47-year-old woman who developed a bad case of ringworm – known as tinea – while travelling in Bangladesh.
A rash had developed across her thighs and buttocks and health officials reported that the severe tinea did not improve after antifungal creams were used.
The woman’s infection was caused by a relatively new species of ringworm-causing fungus called Trichophyton indotineae.
Dr Avrom Caplan, an assistant professor of dermatology at NYU Grossman School of Medicine, who treated the patient and was one of the report’s authors, told NBC News: “My radar went up immediately.”
After the woman returned to the US, she visited the hospital’s emergency ward three times for help. Doctors gave several treatments, typically used for ringworm, but there was no improvement by December.
After many attempts, doctors gave the woman a four-week course of griseofulvin therapy, typically used to treat skin infections such as athlete’s foot and ringworm. But, doctors are still looking into other treatment options.
The woman’s son and husband, who live with her and have had similar rashes, are now undergoing evaluation.
Over the past decade, infections from this drug-resistant fungus have spread rapidly in South Asia, likely driven by overuse of medications to treat them, including topical antifungals and corticosteroids, the CDC report said.
Another case of the skin infection
Another patient, 28, developed the skin infection in 2021 during her third trimester of pregnancy.
She had no underlying medical conditions, no exposure to a person with a similar rash and no international travel history.
The rash was found across the woman’s body, including her neck, abdomen, pubic region and buttocks.
She was later diagnosed with tinea and began oral terbinafine therapy in January 2022 after giving birth to her baby.
However, as the rash did not clear up, the patient was then given itraconazole treatment – an antifungal cream.
The rash resolved after four weeks but continues to be monitored for potential recurrence of the infection.
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What is ringworm, and how is it treated?
According to the NHS, ringworm is a common fungal infection.
The main symptom of the infection is a rash that may look red, silver, or darker than the surrounding skin, depending on your skin tone.
A case of ringworm or tinea infection. File pic
The NHS website also states that the rash can be scaly, dry, swollen or itchy.
Ringworm can be passed on through close contact with:
• A person or animal that is already infected
• Objects that are harbouring the infection, such as bedsheets, combs or towels
• Soil containing the infection, although the NHS has said this is less common
The CDC has said that treatments for ringworm depend entirely on its location on the body and how serious the infection is.
Some forms of ringworm can be treated with over-the-counter drugs, while others may need treatment with prescription anti-fungal medication.
Actress Diane Keaton, who starred in films including The Godfather and Annie Hall, has died aged 79.
Keaton’s daughter, Dexter Keaton White, confirmed her death in California to Sky’s US partner network NBC News.
With a long career, across a series of movies that are regarded as some of the best ever made, Keaton was widely admired.
She was awarded an Oscar, a BAFTA and two Golden Globe Awards, and was also nominated for two Emmys, and a Tony, as well as picking up a series of other Academy Award and BAFTA nominations.
Diane Keaton, with her best actress Oscar for Annie Hall in 1978. Pic: AP
Her best actress Oscar was for the Woody Allen film Annie Hall, which is said to be loosely based on her life.
She appeared in several other Allen projects, including Manhattan, as well as all three Godfather movies, in which she played Kay, the wife and then ex-wife of Marlon Brando’s son Michael Corleone, played by Al Pacino, opposite him as he descends into a life of crime and replaces his father in the family’s mafia empire.
With Woody Allen in 1978. Pic: Adam Scull/PHOTOlink.net/AP
Keaton was the kind of actor who helped make films iconic and timeless, from her heartbreaking turn as Kay Adams-Corleone to the “La-dee-da, la-dee-da” phrasing as Annie Hall, bedecked in the now famous necktie, bowler hat, vest and khakis.
Keaton also frequently worked with Nancy Meyers, starting with 1987’s Baby Boom.
Their other films together included 1991’s Father Of The Bride and its 1995 sequel, as well as 2003’s Something’s Gotta Give.
Keaton (centre) with Goldie Hawn (L) and Bette Midler at the premiere of The First Wives Club in 1996. Pic: AP
In 1996, she starred opposite Goldie Hawn and Bette Midler in The First Wives Club, about three women whose husbands had left them for younger women.
More recently, she collaborated with Jane Fonda, Mary Steenburgen and Candice Bergen on the Book Club films.
‘Brilliant, beautiful’
The unexpected news of Keaton’s death was met with shock around the world.
Diane Keaton shows her hands after placing them on fresh cement during a ceremony TCL Chinese Theatre in 2022. Pic: Reuters
Her First Wives Club co-star Midler wrote on Instagram: “The brilliant, beautiful, extraordinary Diane Keaton has died. I cannot tell you how unbearably sad this makes me.
“She was hilarious, a complete original, and completely without guile, or any of the competitiveness one would have expected from such a star. What you saw was who she was … oh, la, lala!”
Fellow co-star Goldie Hawn said Keaton had left “a trail of fairy dust, filled with particles of light and memories beyond imagination”.
“How do we say goodbye? What words can come to mind when your heart is broken? You never liked praise, so humble, but now you can’t tell me to ‘shut up’ honey. There was, and will be, no one like you,” Hawn added in a post on Instagram.
“You stole the hearts of the world and shared your genius with millions, making films that made us laugh and cry in ways only you could.”
Actor Ben Stiller paid tribute on X, writing: “Diane Keaton. One of the greatest film actors ever. An icon of style, humor and comedy. Brilliant. What a person.”
Kate Hudson, Goldie Hawn’s daughter, posted simply: “We love you so much Diane.”
Last year at New York Fashion Week. Pic: AP
In her Instagram tribute, Emmy, Grammy, Oscar, and Tony award-winning actress and producer Viola Davis said: “No!! No!!! No!! God, not yet, NO!!! Man… you defined womanhood.
“The pathos, humor, levity, your ever-present youthfulness and vulnerability – you tattooed your SOUL into every role, making it impossible to imagine anyone else inhabiting them.
“You were undeniably, unapologetically YOU!!! Loved you. Man… rest well. God bless your family, and I know angels are flying you home.”
Diane Keaton and her children, Duke (left) and Dexter Keaton, at the premiere of ‘Book Club’ in 2018. Pic: AP
Keaton never married.
She adopted her daughter Dexter at the age of 50 in 1996 and a son, Duke, four years later.
There are no survivors from a factory explosion that ripped through a munitions plant in rural Tennessee, police have confirmed.
Eighteen people were missing after the huge blast, but Humphreys County Sheriff Chris Davis has now confirmed all died.
It happened on Friday morning at Accurate Energetic Systems, a company which supplies and researches explosives for the military.
Officers guard the gate at Accurate Energetic Systems military explosives plant. Pic: Reuters
It scattered debris over at least half a mile (800m) and was felt by residents more than 15 miles (24km) away, Mr Davis said.
Aerial footage showed the company’s hilltop location smouldering and obliterated by smoke for much of Friday, with just a mass of twisted metal, burned-out shells of cars, and an array of debris left behind.
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Emergency services have been unable to fully attend the site due to secondary blasts.
Mr Davis described it as one of the worst scenes he had ever seen.
“What we need right now is we need our communities to come together and understand that we’ve lost a lot of people,” he said.
The cause of the blast, which occurred about 60 miles southwest of Nashville, is not yet known but Mr Davis said it could be days, weeks or even months before foul play is ruled out.
Guy McCormick, a supervisory special agent with the Bureau of Alcohol, Tobacco, Firearms and Explosives said experts need to make the area safe before specialist investigators begin combing through the remains.
He said the safety and security of the scene could change quickly because of the heat and pressure caused by the explosion.
Signs near the site on Saturday asked for prayers for the families.
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Terry Bagsby, 68, who works at a petrol station nearby, said people in the close-knit community were “very, very sad”.
“I don’t know how to explain it… Just a lot of grief,” he added.
Actress Diane Keaton, who starred in films including The Godfather and Annie Hall, has died aged 79.
Keaton’s daughter, Dexter Keaton White, confirmed her death to Sky’s US partner network NBC News.
With a long career, across a series of movies that are regarded as some of the best ever made, Keaton was widely admired.
She was awarded an Oscar, a BAFTA and two Golden Globe Awards, and was also nominated for two Emmys, and a Tony, as well as picking up a series of other Academy Award and BAFTA nominations.
Diane Keaton, with her best actress Oscar for Annie Hall in 1978. Pic: AP
Her best actress Oscar was for the Woody Allen film Annie Hall which is said to be loosely based on her life.
She appeared in several other Allen projects, including Manhattan, as well as all three Godfather movies, in which she played Kay, the wife and then ex-wife of Marlon Brando’s son Michael Corleone, played by Al Pacino, opposite him as he descends into a life of crime and replaces his father in the family’s mafia empire.
With Woody Allen in 1978. Pic: Adam Scull/PHOTOlink.net/AP
Keaton was the kind of actor who helped make films iconic and timeless, from her heartbreaking turn as Kay Adams-Corleone to the “La-dee-da, la-dee-da” phrasing as Annie Hall, bedecked in the now famous necktie, bowler hat, vest and khakis.
Keaton also frequently worked with Nancy Meyers, starting with 1987’s Baby Boom.
Their other films together included 1991’s Father Of The Bride and its 1995 sequel, as well as 2003’s Something’s Gotta Give.
In 1996, she starred opposite Goldie Hawn and Bette Midler in The First Wives Club, about three women whose husbands had left them for younger women.
Keaton (centre) with Goldie Hawn (L) and Bette Midler at the premiere of The First Wives Club in 1996. Pic: AP
More recently, she collaborated with Jane Fonda, Mary Steenburgen and Candice Bergen on the Book Club films.
‘Brilliant, beautiful’
Diane Keaton. Pic: AP
The unexpected news was met with shock around the world.
Her First Wives Club co-star Midler wrote on Instagram: “The brilliant, beautiful, extraordinary Diane Keaton has died. I cannot tell you how unbearably sad this makes me.
“She was hilarious, a complete original, and completely without guile, or any of the competitiveness one would have expected from such a star. What you saw was who she was … oh, la, lala!”
Actor Ben Stiller paid tribute on X, writing: “Diane Keaton. One of the greatest film actors ever. An icon of style, humor and comedy. Brilliant. What a person.”
Kate Hudson, whose mother is Goldie Hawn, posted simply: “We love you so much Diane.”
In her Instagram tribute, Emmy, Grammy, Oscar, and Tony award-winning actress and producer Viola Davis said: “No!! No!!! No!! God, not yet, NO!!! Man… you defined womanhood.
“The pathos, humor, levity, your ever-present youthfulness and vulnerability – you tattooed your SOUL into every role, making it impossible to imagine anyone else inhabiting them.
“You were undeniably, unapologetically YOU!!! Loved you. Man… rest well. God bless your family, and I know angels are flying you home.”
Keaton never married. She adopted her daughter Dexter in 1996 and a son, Duke, four years later.
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