Officers were then called to Milton Street, in the city centre, where a driver had tried to run over people in a van. One person is in a critical condition, two others have minor injuries.
The man in his fifties was found dead with knife injuries by a member of the public in nearby Magdala Road.
The University of Nottingham said it was “shocked and devastated” as it revealed two of its students were among the dead.
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0:28
Footage appears to show man being arrested
Police have arrested a 31-year-old man on suspicion of murder and he remains in custody.
Video appears to show him on the ground next to the van as officers detained him.
Photos of the vehicle show small cracks on the windscreen and apparent damage to the bumper.
Chief Constable Kate Meynell said they believe it was stolen from the middle-aged victim and used to drive at members of the public.
Image: Forensics officers on Ilkeston Road
Police are working alongside specialist terror officers, but say they are keeping an “open mind” over the motive and are not looking for anyone else.
Hours after the attacks, at around 12.30pm, there was a “flurry of activity” as armed police cut off Ilkeston Road – where the students were stabbed, said Sky correspondent Becky Johnson.
She said two young women were put in the back of a marked car after officers appeared to enter a commercial property.
Chief Constable Meynell later said a number of searches had been carried out across the city but no further arrests.
Pair ‘stabbed by attacker in black’
A witness told the BBC he saw a man and woman being stabbed on Ilkeston Road at around 4am.
He said he heard “awful, blood-curdling screams” and there was a “black guy dressed all in black with a hood and rucksack grappling with some people”.
He said the woman was shouting for help.
“I saw him stab the lad first and then the woman. It was repeated stabbing – four or five times. The lad collapsed in the middle of the road,” the witness said.
“The girl stumbled towards a house and didn’t move. The next minute she had disappeared down the side of a house, and that’s where they found her.
“I’d say it all happened within five or six minutes. The attacker then just walked off up Ilkeston Road towards town, as calm as anything.”
The man called police, who arrived in about five minutes, before paramedics tried to revive the pair for 40 minutes.
‘I saw two people on the floor’
Another witness, who gave her name as Frances, told Sky News she heard a sudden bang and screaming as a white van drove into people in the city centre.
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2:16
Suspect used victim’s van to drive at three people
She said she “crossed over the road at Theatre Royal and got around 10 feet down the road when all of a sudden you heard a bang – which sounded like a vehicle hitting a bollard”.
“I turned around and then saw the two people on the floor, on the road,” she added.
“Someone was screaming, I think a gentleman ran over to help as well.
“Then it just went from there, the police were there straight away, then the ambulance arrived and they got the two people in the ambulance and got them sent off to whichever hospital.”
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Initially, only those with a body mass index of over 40 who have at least four other health problems linked to obesity will be eligible.
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0:21
Can you get pregnant when on weight loss drugs?
Some doctors have raised concerns about the additional workload this new programme will bring, while pharmacists fear it could lead to supply shortages.
Dr Claire Fuller from NHS England said: “We urgently need to address rising levels of obesity and prioritise support for those who are experiencing severe ill health – and greater access to weight loss drugs will make a significant difference to the lives of those people.”
She added: “While not everyone will be eligible for weight loss drugs, it’s important that anyone who is worried about the impact of their weight on their health discusses the range of NHS support available with their healthcare professional.”
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1:22
Weight loss drugs ‘changing way we see obesity’
The chairwoman of the Royal College of GPs welcomed NHS England’s decision to pursue a phased rollout, and said current workloads must be factored in to ensure the jabs can be prescribed safely.
Professor Kamila Hawthorne went on to say: “While weight loss medications have a lot of potential benefits for patients who are struggling to lose weight and who meet all the clinical criteria for a prescription, they mustn’t be seen as a ‘silver bullet’ to aid weight loss.
“We also need to see a focus on prevention, stopping people becoming overweight in the first place so they don’t require a medical intervention later.”
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9:19
‘How I tried to get weight loss drugs’
Her remarks were echoed by the National Pharmacy Association’s chairman Olivier Picard, who says “prescribing these medications alone misses the point”.
He argued that they need to be part of a comprehensive strategy that includes lifestyle coaching, exercise and nutritional guidance – but many GPs currently “lack the bandwidth” to provide this support.
“As a result, we could end up in a situation where patients are prescribed the medication, lose weight, and then experience rebound weight gain once the course ends – simply because the foundational lifestyle changes weren’t addressed,” Mr Picard added.
Estimates suggest about 29% of the adult population is obese.
Health Secretary Wes Streeting says the government “is determined to bring revolutionary modern treatments to everyone who needs them, not just those who can afford to pay”.
Metropolitan Police Commissioner Sir Mark Rowley says he is “shocked and frustrated” at a planned protest in support of Palestine Action.
The demonstration, due to take place in Westminster later, comes as the government moves to ban the group under anti-terror laws.
Activists from Palestine Action hit the headlines last week after targeting RAF Brize Norton and damaging two military aircraft in a significant security breach.
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Sir Mark said that – until this happens – the force has “no power in law” to prevent the protest from taking place, but lawbreakers will be “dealt with robustly”.
He added: “This is an organised extremist criminal group, whose proscription as terrorists is being actively considered.
“Members are alleged to have caused millions of pounds of criminal damage, assaulted a police officer with a sledgehammer and last week claimed responsibility for breaking into an airbase and damaging aircraft.
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“Multiple members of the group are awaiting trial accused of serious offences.”
Image: Trump’s golf course in Ayrshire was vandalised by Palestine Action. Pic: PA
Over the weekend, Business Secretary Jonathan Reynolds said he could not rule out the possibility of a foreign power being behind Palestine Action.
Any move to proscribe the group must be debated and approved by MPs and peers.
Speaking to Sunday Morning With Trevor Phillips on Sky News, former justice secretary Lord Charlie Falconer suggested that vandalising aircraft would not solely provide legal justification for such a move.
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2:45
Plans to ban activist group criticised
Lord Falconer said: “I am not aware of what Palestine Action has done beyond the painting of things on the planes in Brize Norton, they may have done other things I didn’t know.
“But generally, that sort of demonstration wouldn’t justify proscription so there must be something else that I don’t know about.”
Palestine Action has staged a series of protests in recent months – spraying the offices of Allianz Insurance in London, and vandalising Donald Trump’s golf course in Ayrshire.
Sir Keir Starmer has said stability in the Middle East is “a priority” following US strikes on Iran’s nuclear facilities, as the world has reacted to the attack.
The prime minister also called on Iran to “return to the negotiating table” to “reach a diplomatic solution to end this crisis”.
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2:30
US strikes on Iran explained
In a statement, Sir Keir said: “Iran’s nuclear programme is a grave threat to international security.
“Iran can never be allowed to develop a nuclear weapon, and the US has taken action to alleviate that threat.
“The situation in the Middle East remains volatile and stability in the region is a priority.
“We call on Iran to return to the negotiating table and reach a diplomatic solution to end this crisis.”
The UK was not involved in the strikes but was informed about them in advance by the US, Business Minister Jonathan Reynolds told Sky News’ Sunday Morning with Trevor Phillips.
Sir Keir and Foreign Secretary David Lammy had been pushing for a diplomatic solution. On Thursday, the prime minister warned of a “real risk of escalation” in the conflict.
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3:34
Trump: Iran strikes ‘spectacular success’
The US struck three sites in Iran early on Sunday morning, with Donald Trump boasting the country’s key nuclear sites were “completely and fully obliterated” in an address to the nation from the White House and warned there could be further strikes if Iran retaliates.
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1:20
‘Trump’s bold decision will change history’
Netanyahu praises Trump
Israel‘s Prime Minister Benjamin Netanyahu praised Mr Trump for the strikes, saying: “Your bold decision to target Iran’s nuclear facilities with the awesome and righteous might of the United States will change history…
“History will record that President Trump acted to deny the world’s most dangerous regime the world’s most dangerous weapons.”
UN secretary-general ‘gravely alarmed’ by US attack
But UN secretary general Antonio Guterres said he was “gravely alarmed by the use of force” by the US against Iran.
“This is a dangerous escalation in a region already on the edge – and a direct threat to international peace and security. There is a growing risk that this conflict could rapidly get out of control – with catastrophic consequences for civilians, the region, and the world.”
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European Union foreign policy chief Kaja Kallas urged all sides to step back and return to the negotiating table. “Iran must not be allowed to develop a nuclear weapon,” she said in a post on X.
“I urge all sides to step back, return to the negotiating table and prevent further escalation,” she said, adding that EU foreign ministers will discuss the situation tomorrow.
Image: Cuba’s President Miguel Diaz-Canel. Pic: Reuters
How the world reacted to the strikes
Cuba’s President Miguel Diaz-Canel said on X: “We strongly condemn the US bombing of Iran’s nuclear facilities, which constitutes a dangerous escalation of the conflict in the Middle East.
“The aggression seriously violates the UN Charter and international law and plunges humanity into a crisis with irreversible consequences.”
Venezuela’s foreign minister Yvan Gil said his country’s government “condemns US military aggression” and “demands an immediate cessation of hostilities”.
In a statement, an Australian government spokesperson said Iran’s nuclear and ballistic missile programme “has been a threat to international peace and security”.
Image: Japan’s Prime Minister Shigeru Isiba. Pic: Reuters
Japan’s Prime Minister Shigeru Ishiba said it is “crucial that there be a quick de-escalation of the conflict”.
Italy’s foreign minister Antonio Tajani said after the attack that his country’s government hopes “a de-escalation can begin and Iran can sit down at the negotiating table”.
The US attack came after more than a week of strikes by Israel, which have significantly degraded Iran’s air defences and offensive missile capabilities, and damaged its nuclear enrichment facilities.
Israel’s strikes on Iran have killed at least 865 people and wounded 3,396 others, according to the Washington-based group Human Rights Activists. The group said of those killed, 365 were civilians and 215 were security force personnel.