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Billionaire entrepreneur Elon Musk expects his brain-chip startup Neuralink to start its first human trial this year, he said on Friday in France.

Speaking at the VivaTech event in Paris, co-founder Musk said Neuralink plans to implant a tetraplegic or paraplegic patient during a webcast monitored by Reuters. While Musk didn’t specify how many patients his company would implant or for how long, “it’s looking like the first case will be later this year,” said Musk, who is also CEO of electric carmaker Tesla, social media platform Twitter and the SpaceX rocket launch company.

Last month, Neuralink said it received US Food and Drug Administration (FDA) clearance for its first-in-human clinical trial, a critical milestone for the startup as it faces US probes over its handling of animal experiments. The FDA acknowledged in an earlier statement to Reuters that the agency cleared Neuralink to use its brain implant and surgical robot for trials but declined to provide more details.

If Neuralink can prove its device is safe in humans, it would still take several years, potentially more than a decade, for the start-up to secure commercial use clearance, experts earlier told Reuters. The company is also competing with other neurotech companies which have already implanted their devices in people.

Musk has missed timelines on his public pronouncements about Neuralink before, however. On at least four occasions since 2019, Musk predicted that Neuralink would soon start human trials.

The company, founded in 2016, first sought permission from the FDA in early 2022, and the agency rejected the application, citing dozens of safety concerns, Reuters has reported. Some of the issues involved the lithium battery of the device, the possibility of the implant’s wires migrating within the brain, and the challenge of safely extracting the device without damaging brain tissue.

Neuralink also faces federal scrutiny following Reuters reports about its animal experiments.

Last year, Neuralink employees told Reuters the company was rushing and botching surgeries on monkeys, pigs and sheep, resulting in more animal deaths than necessary, as Musk pressured staff to receive FDA approval. The animal experiments produced data intended to support the company’s application for human trials, the sources said.

In one instance in 2021, the company implanted 25 out of 60 pigs with the wrong-sized devices. All the pigs were subsequently killed – an error that employees said could have been easily avoided with more preparation.

In May, US lawmakers urged regulators to investigate whether the makeup of Neuralink’s panel overseeing animal testing contributed to botched and rushed experiments after Reuters reported on potential financial conflicts on the board.

The Department of Transportation is separately probing whether Neuralink illegally transported dangerous pathogens on chips removed from monkey brains without proper containment measures. An agency spokesperson said on Friday the investigation is ongoing.

Neuralink has also been under investigation by the US Department of Agriculture’s Office of Inspector General for potential animal-welfare violations. This probe has been looking at the USDA’s oversight of Neuralink. An agency spokesperson didn’t immediately respond to a comment request.

Meanwhile, the company’s valuation has shot up in recent months. The start-up was valued at close to $2 billion (roughly Rs. 16,382 crore) in a private fundraising round two years ago and is now worth around $5 billion (roughly Rs. 40,955 crore) based on privately executed stock trades, Reuters reported this month. Neuralink employees who sat on the company’s animal board, which has come under federal scrutiny for potential financial conflicts, stood to benefit from the implant’s quick development. Neuralink stock that some of the employees hold has jumped around 150% in value in just two years, based on the secondary trades, Reuters reported.

© Thomson Reuters 2023


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Nasa Experiment Hints Solar Wind May Help Make Lunar Water

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Nasa Experiment Hints Solar Wind May Help Make Lunar Water

A recent study indicates that water on the lunar surface may come from the solar wind. Water—of most importance as rocket fuel—is present in lunar surface dust, or regolith, produced by meteoroids and charged particles impacting lunar rock. The researchers discovered that several of this graph had evidence of dampness, with between 200 and 300 parts per million of water and the molecule hydroxyl. The water and hydroxyl in the lunar graph were both low in deuterium, suggesting their hydrogen came from the sun, likely delivered to the moon by solar winds.

When the hydrogen particles interact with oxygen present in lunar surface rocks, water molecules arise. The results suggest that other airless bodies in the solar system may also have water on their surfaces, therefore highlighting the possibility of finding such water on the surface of other such objects.

NASA Confirms Solar Wind May Create Water on the Moon’s Surface

As per the report, it is claimed that scientists have hypothesised—since the 1960s—that the Sun is the source of elements generating water on the Moon. The idea is that water molecules would be produced by a chemical reaction set off by a stream of charged particles—the solar wind— slamming onto the lunar surface. NASA-led researchers have confirmed this prediction in the most realistic lab simulation of this process yet.

Given much of the water on the Moon is believed to be frozen in continuously shadowed areas at the poles, the result affects NASA’s Artemis astronaut activities near the South Pole.

Solar Wind Can Create Water on the Moon, NASA Lab Test Confirms

Constantly flowing from the sun, solar wind is mostly composed of protons—nuclei of hydrogen atoms deprived of their electrons. Our planet’s magnetic shield and atmosphere help most of the solar particles to avoid reaching the surface of Earth. But the Moon has no such protection. As computer models and lab experiments have shown, when protons smash into the Moon’s surface, which is made of a dusty and rocky material called regolith, they collide with electrons and recombine to form hydrogen atoms.

Scientists have discovered proof of both hydroxyl and water molecules beneath the moon’s surface. These molecules leave a chemical imprint that interacts with light on the regolith. Generally speaking, “water” refers to either one or a mix of both molecules since hydroxyl and water cannot be differentiated right now.

NASA astronaut Yeo and colleagues examined Apollo lunar samples using a customised tool employing two samples worth of dust. Their little particle accelerator battered the dust to create a copy of solar wind spanning many days.

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Tyrannosaurus Rex Fossils Are Being Horded by Private Buyers: Study

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Tyrannosaurus Rex Fossils Are Being Horded by Private Buyers: Study

A new study has found that the private trade in Tyrannosaurus rex fossils is hampering researchers’ understanding of the iconic Cretaceous predator. Thomas Carr, an associate professor of biology at Carthage College, found that there are now more scientifically valuable T. rex specimens in private or commercial ownership than in public museums and other public trusts. The private market is likely to be an underestimate, as commercial companies are discovering twice as many T. rex fossils as museums.

Private Fossil Trade Threatens T. rex Research Progress

Carr concentrated on “scientifically informative” specimens—heads, skeletons, and isolated bones—to understand exactly how the private market sets the limitations for researchers able to obtain T. rex fossils. The most valued dinosaur sold in 2024 was a Stegosaurus, which sold for $44.6 million ; Carr wants to bring attention to his work so that other researchers may investigate how the commercial market is influencing other extinct species, including the T. rex.

As per the study, it is claimed that the private trade in Tyrannosaurus rex fossils is compromising knowledge of the famous Cretaceous predator. Director of the Carthage Institute of Palaeontology in Wisconsin and associate professor of biology at Carthage College, Thomas Carr, discovered that private or commercial ownership of T. rex specimens currently numbers more than those in public museums and other public trusts. The loss of juvenile and subadult specimens is especially worrisome, as the early growth stages of T. rex are bedevilled by a poor fossil record, and the loss of them carries the heaviest scientific cost.

Study Reveals T. rex Fossils Vanishing into Private Hands

Carr published his findings, titled “Tyrannosaurus rex: An endangered species,” in the journal Palaeontologia Electronica. He targeted “scientifically informative” specimens, such as skulls, skeletons, and isolated bones, to better understand the private market’s impact on the number of T. rex fossils available to researchers. He found 61 specimens in public trusts overall and 71 specimens—including 14 juveniles—in private ownership.

Driven by the luxury fossil market spanning all types of dinosaurs, private sales of dinosaurs outside of T. rex, as he has done with the T. rex, and the most expensive auction ever for a stegosaurus for $44.6 million in 2024, Carr believes his effort will motivate other academics to investigate how the commercial market is impacting other ancient animals.

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Rare Ancient DNA Found in the Sahara Desert Unwinds the Verdant Past

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Rare Ancient DNA Found in the Sahara Desert Unwinds the Verdant Past

The silence of the Sahara desert unveils the evidence of a verdant past rooted in North African lineage, published on 2 April in the Journal Nature. The study took place in the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, together with an archaeological mission in the Sahara at Sapienza University of Rome, revealed that the two mummified individuals discovered from the Takarkori rock shelter in southwest Libya dated back over 7000 years. The findings predict the genetic history of early North African populations during the African Humid Period.

Genome Analysis

The Sahara desert was once a green savannah between 14,500 and 5000 years from the present, along the water bodies that promoted human occupation with pastoralism in the Holocene epoch. The Sahara Desert has rare DNA preservation due to its present habitat, leading to limited knowledge of genetic history. However, the Sahara was not a barren land that we know today; in fact, a green and fertile land dotted with grasslands and lakes. The study suggests that the DNA retrieval unveils a previously unknown North African ancestral lineage.

Evidence from the analysis predicts that these ancient people were different from both sub-Saharan and Eurasian groups, signalling a unique North African crowd that played a crucial role in the prehistoric period. However, the DNA contains no direct evidence of blending with neighbouring areas of that time. This, in turn, highlights the genetic isolation and importance in the history of human evolution.

The Takarkori individuals are closely related to the ancestors from Taforalt Cave, Morocco, linked with the Iberomaurusian lithic industry and predating the AHP (Analytic Hierarchy Process). However, Takarkri individuals show ten times less Neanderthal hierarchy than Valentine farmers, still significantly more than present sub-Saharan genomes. Taforalt individuals have half the Neanderthal blend of non-Africans.

Findings and Implications

The study demonstrates not just reshaping the understanding of ancient North African hierarchy but also puts strong emphasis on the importance of the Green Sahara in the past. Not just that, pastoralism flourished through cultural diffusion into a divergent, isolated North African ancestral lineage that spread in North Africa at the time of the late Pleistocene epoch. Researchers continue to explore the region, and there could be more secrets unleashed from this vast green landscape, bridging the gaps in the human origins story.

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