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After just 15 minutes on the streets of Philadelphia’s Kensington neighbourhood, an encounter that was everything. 

It was illustrative of a crisis out of control, it was reflective of a profound personal struggle, it was instructive of the power of addiction, and it was deeply, deeply sad.

“I really didn’t have anybody taking me seriously,” Christophe said to me as he explained why he was where he was.

“I was this young guy, a semi-pro athlete.”

He explained how it had all begun with an injury.

Painkillers, prescribed at first, then self-medicated. Then illicit opioids. Now this new drug, Tranq.

He was fluent, eloquent, thoughtful, and as he told me his truncated life story, he was injecting himself in the left arm.

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It didn’t take long. Seconds. He trailed off. A mumble.

Then nothing. His body stooped.

The hit had hit. He was almost out. He stumbled over to the curb and slumped down. Less than a minute later, he was unconscious.

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Christophe injected Tranq while speaking to Sky News

Stone - Philadelphia
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Christophe slumped to the floor after his hit

I was last here in Philadelphia in February.

We’d gone then to investigate a new street drug which was leaving the most horrific wounds on those who use it. What we found then was shocking, devastating and truly depressing.

I’ve come back now because there’s news that the story of the so-called “zombie drug” has taken a turn.

America’s top drug prevention officials have been analysing nationwide data to see if this new drug, which had first emerged in these Philadelphia streets, is actually more widespread than they had thought.

What they have discovered is alarming.

New analysis of data stretching back to 2019 now shows a jump in Xylazine-related deaths of 276% nationwide. Deaths are more than doubling every year across America.

The drug, a cattle tranquiliser that is mixed by dealers into the existing opioid street drug supply, has now been detected in 48 of the 50 US states. Less than a year ago, they thought it had only been found in Philadelphia.

Regular unadulterated opioids are already killing more than 100,000 Americans every year. So news that xylazine is now so widespread is devastating for users, for volunteers and for the authorities who by our judgment have no control of this crisis.

Read more:
How drug leaves million-dollar streets strewn with bodies
‘Tranq’ designated ‘threat to the nation’
What is fentanyl?

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Christophe eventually passed out

In Philadelphia, I wanted to see how the users and volunteers I’d met back in February were doing and what they made of a major new “action plan” that President Biden has asked his officials to initiate.

Before Christophe had succumbed to his latest hit, he had seemed encouraged by the news from the White House.

Access to addiction treatment was key, he’d said.

Our guide through these dangerous streets was Ronnie Kaiser, who runs the charity Angels in Motion. She’d shown us around back in February and was keen to do so again.

I watched as she checked on Christophe.

“He has a pulse. He’s not overdosing at the moment,” she said.

The hopelessness here is breathtaking. There are people openly injecting on every street corner; far more than back in February, for sure.

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Ronnie checks Christophe after he injects Tranq

Their addiction is more powerful than the recognition to treat the wounds which appear all over their bodies. Access to treatment – both physical and mental – is so hard. And there is so little in the way of a safety net in America.

“It’s gotten worse,” Ronnie said as we drove past one group of people, all unconscious.

Users must navigate America’s complex and expensive health system if they are to stand a real chance of recovery.

The government’s national plan involves access to prevention, harm reduction treatment and recovery support, as well as bold actions to disrupt the supply from China via Mexico.

“I’m glad they’re finally implementing something. I just hope that the implementation is fast enough and it’s the correct one. Most people here have either mental health or trauma that’s been in their life,” Ronnie told me.

She pointed to the perennial American problem of medical insurance and the “for profit” medical facilities.

“We need federal rehabs, federal recovery houses, the ability for longer rehab stays and definitely all insurances to be accepted at all rehabs,” she said.

Officials in the Biden administration do seem to be recognising the scale of the problem, but now with such profound challenges facing them.

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Dr Rahul Gupta is the White House’s drug policy lead

Joe Biden’s director of national drug control policy, Dr Rahul Gupta, agreed to talk to us.

“On the streets here it looks like failure,” I said to him. “It looks like you have not remotely got a grip of the crisis here in Philadelphia and across the country.”

He conceded: “I think what you’re seeing and what I have seen on the streets of Philadelphia, specifically on Kensington Avenue, is an example of what does happen when we are not implementing those policies.”

“What I’ve seen is so much suffering. A lot of the people do not have homes. A lot of the people need help in an urgent way,” Dr Gupta said.

But he insisted the changes are having an impact: “The policy change that has occurred with prioritising harm reduction, prioritising treatment, meeting people where they are is working.”

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Christophe took a few minutes to come around. The hits are intense, but they are short and, of course, highly addictive.

“Sorry,” he said. He wanted to finish his story.

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At least eight people killed in car explosion in New Delhi, police say

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At least eight people killed in car explosion in New Delhi, police say

At least eight people have been killed and at least 19 others injured after a car exploded in New Delhi, say Indian police.

The blast, which triggered a fire that damaged several vehicles parked nearby, happened at the gates of the metro station at the Red Fort, a former Mughal palace and a busy tourist spot.

New Delhi’s international airport, metro stations and government buildings were put on a high security alert after the explosion, the government said. The cause of the explosion is being investigated.

The city’s police commissioner, Satish Golcha, said it happened a few minutes before 7pm.

“A slow-moving vehicle stopped at a red light. An explosion happened in that vehicle, and due to the explosion,
nearby vehicles were also damaged,” he told reporters.

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Local media said at least 11 people were injured and that Mumbai and Uttar Pradesh state had been put on high alert after the incident

Police officers and forensic technicians work at the site of the explosion. Pic: Reuters
Image:
Police officers and forensic technicians work at the site of the explosion. Pic: Reuters

The site of the explosion. Pic: Reuters
Image:
The site of the explosion. Pic: Reuters

One resident, who did not give a name, told NDTV: “We heard a big sound, our windows shook.”

Sanjay Tyagi, a Delhi police spokesman, said they were still investigating the cause, while the fire service reported that at least six vehicles and three autorickshaws had caught fire.

Images show the burnt-out remnants of several cars and forensic officers at the scene.

The scene has now been sealed off. Pic: Reuters
Image:
The scene has now been sealed off. Pic: Reuters

Home minister Amit Shah told local media that a Hyundai i20 car exploded near a traffic signal close to the Red Fort. He said CCTV footage from cameras in the area will form part of the investigation.

“We are exploring all possibilities and will conduct a thorough investigation, taking all possibilities into account,” Shah said. “All options will be investigated immediately, and we will present the results to the public.”

The investigation is being conducted by the National Investigation Agency, India’s federal terror investigating agency, and other agencies.

India’s Prime Minister Narendra Modi offered his condolences to those who have lost their loved ones in the blast.

He posted on X: “May the injured recover at the earliest. Those affected are being assisted by authorities.

“Reviewed the situation with Home Minister Amit Shah Ji and other officials.”

This breaking news story is being updated and more details will be published shortly.

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From US enemy to ally? Why ex-jihadist Syrian president’s meeting with Trump is a big deal

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From US enemy to ally? Why ex-jihadist Syrian president's meeting with Trump is a big deal

It is a moment few could have imagined just a few years ago but the Syrian president, Ahmed al Sharaa, has arrived in Washington for a landmark series of meetings, which will culminate in a face-to-face with Donald Trump at the White House.

His journey to this point is a remarkable story, and it’s a tale of how one man went from being a jihadist battlefield commander to a statesman on the global stage – now being welcomed by the world’s most powerful nation.

Mr Sharaa became leader of Syria after the fall of the Bashar al Assad regime in December last year.

Before that he went by the nom de guerre Abu Mohammed al Jolani.

During Syria’s brutal civil war, he was the leader of the Nusra Front – a designated terror organisation, the Syrian branch of al Qaeda.

Back then, the thought of him setting foot on US soil and meeting a US president would have been unthinkable. There was a $10m reward for information leading to his capture.

Ahmed al Sharaa meeting Donald Trump in Riyadh in May. Pic: AP
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Ahmed al Sharaa meeting Donald Trump in Riyadh in May. Pic: AP

So what is going on? Why is diplomacy being turned on its head?

After 14 years of conflict which started during the so-called Arab Spring, Syria is in a mess.

Mr Sharaa – as the head of the transitional government – is seen by the US as having the greatest chance of holding the country together and stopping it from falling back into civil war and failed state territory.

But to do that, Syria has to emerge from its pariah status and that’s what the US is gambling on and why it’s inclined to offer its support and a warm embrace.

Donald Trump, Crown Prince Mohammed Bin Salman and Ahmed al Sharaa in May. Pic: Saudi Press Agency
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Donald Trump, Crown Prince Mohammed Bin Salman and Ahmed al Sharaa in May. Pic: Saudi Press Agency

By endorsing Mr Sharaa, it is hoping he will shed his past and emerge as a leader for everyone and unite the country.

Holding him close also means it’s less likely that Iran and Russia will again be able to gain a strong strategic foothold in the country.

So, a man who was once an enemy of the US is now being feted as a potential ally.

Mr Sharaa meeting Vladimir Putin in Moscow in October. Pic: Reuters
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Mr Sharaa meeting Vladimir Putin in Moscow in October. Pic: Reuters

There are big questions, though. He has rejected his extremist background, saying he did what he did because of the circumstances of the civil war.

But since he took power, there have been sectarian clashes. In July, fighting broke out between Druze armed groups and Bedouin tribal fighters in Sweida.

It was a sign of just how fragile the country remains and also raises concerns about his ability to be a leader for everyone.

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Can Syria’s new president be trusted?

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Nonetheless, Mr Sharaa is viewed as the best chance of stabilising Syria and by extension an important part of the Middle East.

Get Syria right, the logic goes, and the rest of the jigsaw will be easier to put and hold together.

The visit to Washington is highly significant and historic. It’s the first-ever official visit by a Syrian head of state since the country’s independence in 1946.

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Top shot: Syrian leader shows off his basketball skills

The meeting with Donald Trump is, though, the really big deal. The two men met in Riyadh in May but in the meeting later today they will discuss lifting sanctions – crucial to Syria’s post-war reconstruction – how Syria can help in the fight against Islamic State, and a possible pathway to normalisation of relations with Israel.

The optics will be fascinating as the US continues to engage with a former militant with jihadi links.

It’s a risk, but if successful, it could reshape Syria’s role in the region from US enemy to strong regional ally.

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Madagascar’s new president Michael Randrianirina denies coup after taking office following Gen Z uprising

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Madagascar's new president Michael Randrianirina denies coup after taking office following Gen Z uprising

A Gen Z uprising has pushed Madagascar’s former leader Andry Rajoelina, not only out of office but out of the country.

In his place is Colonel Michael Randrianirina, who was sworn in as president of the island nation last month after his military unit joined the protesters.

Sky News’ Africa correspondent Yousra Elbagir sits down with the new leader.

The first question I ask Colonel Randrianirina, as he sits in an ornate mahogany chair in his military fatigues, is how it feels to be in the palace as president.

He sighs and sinks deeper into the chair. He looks humbled and struggles to find the words.

“How do I put it?” he says. “I am happy and it is also a great honour to have come to this palace to be able to help and support the Malagasy people in deep poverty.”

As commander of an elite non-combatant military unit, Corps d’Administration des Personnels et des Services de l’Armée de Terre (CAPSAT), the colonel rode a wave of Gen Z protests to the palace. On 11 October, he shared a video on social media instructing officers to disobey shoot-to-kill orders and support the movement.

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The new Madagascan leader, Colonel Michael Randrianirina
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The new Madagascan leader, Colonel Michael Randrianirina

At least 22 protesters have been killed and more than 100 injured after denouncing the power cuts and water shortages that have come to signify government corruption in the impoverished island nation.

Why did he share the pivotal video?

He says: “I am a military officer but I am also part of the people and I will return to the people. When you feel sorry for what the people are suffering from… they have been poor for so long and wealth has been looted – but you still shoot them and kill them. That was not why I entered the military of Madagascar, to kill people.”

Soon after his speech, soldiers allowed the young protesters rejecting then president Andry Rajoelina to occupy Place du 13 Mai Square on Independence Avenue in the heart of Antananarivo, the island nation’s capital.

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October: Madagascar’s president flees country after coup

Colonel Randrianirina paraded through a crowd and addressed them from the hatch of an armoured vehicle. “The president of the nation has to leave… If that does not happen,” he threatened, “we will see”.

After Mr Rajoelina fled Madagascar on 13 October, the National Assembly voted to impeach him for “desertion of duty”. Three days later, Colonel Randrianirina stood in fatigues in front of the palace. With officers by his side, he announced their seizure of power and the dissolution of the constitution and all government institutions outside of the National Assembly.

Shortly after, the African Union suspended Madagascar‘s membership on account of the military takeover.

A demonstration in Antananarivo last month. Pic: Reuters
Image:
A demonstration in Antananarivo last month. Pic: Reuters

In the palace as president, he insists that this is not a military coup.

“It is support for the people and the country and for us to not be prone to civil war – between the people – between the military officers and your needs, so you adjust helping to support the people to avoid this.

“We were not conducting any coup at all, it was the president [Rajoelina] himself who decided to leave the country.”

Sky News meets Colonel Randrianirina
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Sky News meets Colonel Randrianirina

United Nations secretary-general Antonio Guterres condemned “the unconstitutional change of government in Madagascar” and called for “the return to constitutional order and the rule of law,” when reports of a military takeover first circulated on 16 October. The day we met the new president, he had just been congratulated by France’s President Emmanuel Macron.

Colonel Randrianirina is promising elections in 18 to 24 months, after what he calls a “refoundation and recovery” of the country – a process he admits might take a long time.

Observers are concerned that elections will be postponed and the new president will become another strongman, but Gen Z organisers are holding on to faith that this hard-earned outcome is worth it.

‘We were living under a dictatorship’

I asked a group of five young organisers if they have concerns that the president will become another dictator, just like previous Malagasy rulers who ascended to power off the back of a popular uprising. Ousted president Mr Rajoelina came into power after protests in 2009 that also ended in a CAPSAT-supported coup.

Police patrolling the streets during last month's protests. Pic: AP
Image:
Police patrolling the streets during last month’s protests. Pic: AP

University student Ratsirarisoa Nomena told us: “The new president is not a dictator… he is listening to the people and he is validated by the people.

“We as students also validated him – he is not a dictator because the motivation of the army is from the people for the people.

“We were living under dictatorship. There was no freedom of expression and it was very hard to fight for that in Madagascar. We had to face being injured and losing our lives and the lives of our fellow students. Malagasy citizens who fought with us lost their lives too. This is what we went through – to me, we are halfway to victory.”

Their president is aware of their support and does not credit Gen Z alone for his place in the palace.

“Generation Z are part of the reason [I am here] but the full Malagasy people really wanted change at the time we are speaking,” Mr Randrianirina told me. “The Malagasy people have been suffering for so long and deprived of fundamental rights – no access to water supply and electricity, facing insecurity.

“Malagasy people, including the Gen Z, government officials and trade unions really wanted change so it is the whole Malagasy people that supported me to this point.”

Read more from Sky News:
Ex-jihadist Syrian president to meet Trump

Two dead as Super Typhoon hits Philippines
UK deploying specialist RAF team to defend Belgium from ‘rogue’ drones

Across Africa, young people are showing their disapproval of the old guard.

Gen Z protesters have made their mark in Tanzania, Kenya, Cameroon, Morocco, Mozambique and Nigeria in 2025 alone – denouncing disputed elections and the corruption impacting their futures.

Is the Gen Z coup of Madagascar a warning for old leaders on a young continent?

“I don’t know what to say about the other countries, but I know my own country,” Mr Randrianirina says.

“If tomorrow the people of Madagascar hate me, then I will leave this palace.”

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