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Reviewed by Lily Ramsey, LLM Jul 12 2023

A new $3.9 million grant from the U.S. Food and Drug Administration (FDA) will allow researchers with the Center for Tobacco Research at The Ohio State University Comprehensive Cancer Center to evaluate effects of e-cigarette flavors on the smoking behaviors of current adult smokers.

The study, co-led by Theodore Wagener, PhD, director of Ohio State's Center for Tobacco Research, and Tracy Smith, PhD, of the Medical University of South Carolina (MUSC) Hollings Cancer Center, will be the first to provide definitive information about the impact of non-tobacco e-cigarette flavors for helping adult smokers stop smoking.

Wagener says this study will provide scientific data that are urgently needed to inform the FDA's regulation of flavor use in e-cigarettes.

Youth advocates have strenuously objected to flavored e-cigarettes, arguing that, with flavors like cinnamon bun, cotton candy, bubble gum, mango, strawberry or chocolate, e-cigarettes are enticing young people to take up an addictive and harmful habit. Those flavors might also be more appealing to adults who smoke cigarettes and have been unable to quit. The FDA is currently making regulatory decisions about e-cigarette flavors with incomplete scientific data. Existing data show that smokers also prefer flavored e-cigarettes, and while there are a few survey studies suggesting that flavored e-cigarettes may be more helpful for switching to vaping, these studies are not rigorous enough for the FDA to base its regulatory decisions on. Our study will be the first to provide the FDA with definitive information as to the benefit, if any, of e-cigarette flavors to adult smokers."

Theodore Wagener, PhD, Director of Ohio State's Center for Tobacco Research

While the National Academies of Science, Engineering and Medicine have concluded that e-cigarettes are likely to be far less harmful than combustible cigarettes, Wagener notes that more than 1 million e-cigarette products have been banned since 2020, mostly due to the significant rise in youth vaping, often with flavored e-cigarettes.

Switching to e-cigarettes, while not a completely healthy choice, is thought to be better than continuing to smoke, a concept that public health scientists refer to as "harm reduction." Related StoriesTowards Zika preparedness: immunogenicity insights from vaccine researchUnlocking the brain-lung dialogue key to future treatments for critical care patientsAre flavored e-cigarette bans effective?

Wagener says "the FDA must decide how to balance its goals of protecting young people and offering harm-reduction options to adults. This new trial will generate critical data to help make more informed public health decisions that have a lasting impact.". New study evaluates how much flavoring impacts smoking behavior

This national, randomized, controlled trial will recruit up to 1,500 cigarette users from the across the United States.

Researchers will measure e-cigarette flavor impact on product uptake and appeal, cigarette craving, symptoms, dependence and smoking behavior, including sustained and complete switching from cigarettes to e-cigarettes. They will also utilize combination nicotine replacement therapy (NRT, patch and lozenge) as an FDA-approved comparator to determine the potential increased benefit (or not) of e-cigarettes versus nicotine replacement therapies on smoking. Smokers will be randomized to one of three groups: preferred flavor e-cigarette, tobacco flavor e-cigarette or combination nicotine replacement therapy.

Study participants will receive products at no cost for 14 weeks. Participants in the preferred flavor group will be able to change flavors throughout that time. Changes in smoking will be biochemically confirmed via remote exhaled carbon monoxide readings at 12 weeks and 26 weeks after the product switch date.

"If our study demonstrates no significant improvements in switching with flavored e-cigarette use, then the continued sale of these products is likely indefensible; however, if improvements are significant, these findings will provide a critical counterweight to the current FDA regulations and will aid future decision making," Wagener said. Source:

Ohio State University Wexner Medical Center

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Cyclones name WSU’s Rogers to replace Campbell

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Cyclones name WSU's Rogers to replace Campbell

Washington State coach Jimmy Rogers has agreed to a six-year deal to become the next coach at Iowa State, the school announced Friday.

Iowa State athletic director Jamie Pollard moved quickly to replace departing coach Matt Campbell, who agreed to an eight-year deal to take over Penn State on Friday, and landed Rogers, a proven winner at the FCS level who just concluded his first regular season at Washington State.

“Jimmy Rogers is a rising star in college athletics who has very strong ties to the Midwest both as a player and as a coach,” Pollard said in a statement. “He has been on my short-list ever since the first time I met him. He immediately impressed me with his interest in Iowa State University and told me during our first visit several years ago that he wanted to be the next head coach at Iowa State.

“Since our initial meeting, I have stayed in close contact with him and have been very impressed with his work ethic and understanding of what it takes to be successful at Iowa State,” Pollard added. “He is a proven winner who has demonstrated throughout his career that he will fit our culture.”

Rogers, 38, has a 33-9 record over three seasons as a head coach. He went 6-6 in his debut season at Washington State after overseeing a significant roster rebuild following the departure of coach Jake Dickert to Wake Forest.

“My family and I are excited to be joining the Iowa State University community and the Cyclone football program,” Rogers said in a statement. “Iowa State has been one of the nation’s top programs for the last decade and we look forward to building upon its upward trajectory. I’m extremely grateful for the opportunity that Jamie Pollard has given me to lead the Cyclones.”

Rogers previously spent 12 years at South Dakota State and led his alma mater to an FCS national championship in 2023 with a 15-0 season in his first year as the Jackrabbits’ head coach after taking over for longtime coach John Stiegelmeier.

Rogers carried a 29-game win streak into his second year as coach and achieved a No. 3 finish in 2024 with a run to the FCS playoff semifinals and a 12-3 season.

The Jackrabbits also won the FCS national championship in 2022 after Rogers was elevated to being the team’s sole defensive coordinator, and they played for another FCS title in 2020.

Campbell, the winningest coach in Iowa State history with 72 victories, led the Cyclones to eight winning seasons during his decade at the helm and two appearances in the Big 12 championship game.

The Cyclones went 8-4 this season and are awaiting their bowl selection on Sunday.

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Cool it! JMU AD scolds fans for throwing snowballs

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Cool it! JMU AD scolds fans for throwing snowballs

HARRISONBURG, Va. — James Madison athletic director Matt Roan used the public-address microphone to implore Dukes fans to stop throwing snowballs onto the field during the Sun Belt Conference championship game against Troy on Friday night, warning that their actions could cost JMU a penalty.

Roan’s address to the crowd followed an incident that affected the game.

With 4:30 left in the first quarter, Troy’s Evan Crenshaw was nearly hit by a snowball while punting from the end zone with the JMU student section behind him. Crenshaw shanked a 26-yard punt that helped set up the Dukes’ first score, a 40-yard field goal.

Fans in the student section began throwing snowballs during pregame warmups, when the Dukes’ marching band got pelted. They kept it up for most of the first half, despite repeated warnings over the PA system.

Harrisonburg received about 1½ inches of snow Friday, its first measurable snowfall of the season.

No. 19 JMU had an outside shot at making the College Football Playoff field with a win over Troy and a loss by No. 16 Virginia to Duke in Saturday’s Atlantic Coast Conference championship game.

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No. 1 recruit DT Lamar Brown signs with LSU

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No. 1 recruit DT Lamar Brown signs with LSU

LSU and coach Lane Kiffin closed a busy early signing period with a bang Friday, officially securing the signature of defensive tackle Lamar Brown, ESPN’s No. 1 overall 2026 recruit.

Brown, a 6-foot-5, 285-pound defender from Erwinville, Louisiana, signed his letter of intent on the final day of the three-day period, the program announced, formally joining Kiffin and the Tigers as the program’s first No. 1 overall addition since Leonard Fournette in 2014.

Committed to the program since July, Brown was not initially expected to sign this week following meetings between Brown’s representatives and members of the LSU staff Tuesday.

While Brown remained verbally committed to the program, sources told ESPN that his camp harbored reservations over Kiffin’s to-be-completed coaching staff. Uncertainty hanging over the futures of Tigers interim coach Frank Wilson and defensive coordinator Blake Barker marked a particular concern for Brown, who attends high school on the LSU campus and developed close relationships with the program’s previous staff during his recruitment.

As of Friday afternoon, the Tigers have not publicly announced plans for the program’s defensive staff. The statuses of Wilson and Baker, a reported candidate for multiple head coach openings across the country, remain unclear, too. But according to ESPN sources, Brown and the Tigers progressed toward his signing through talks across Wednesday and Thursday, culminating in the program officially landing his signature Friday afternoon.

Within an impressive Tigers defensive class in 2026, Brown was not alone in initially holding off on signing this week before ultimately submitting the official paperwork.

LSU officially announced the signing of ESPN 300 defensive tackle Richard Anderson (No. 90 overall) on Thursday after questions swirled over his signature on the opening day of the signing period. Top 60 defensive linemen Deuce Geralds (No. 39) and Trenton Henderson (No. 60) each pushed their signings to Friday. Henderson, amid late flip efforts from Auburn and Florida State, gave the Tigers his signature Friday morning. Geralds, ESPN’s No. 2 defensive tackle in 2026, followed in the afternoon, minutes before the program announced Brown’s signing.

For Kiffin, who officially arrived Sunday, Brown’s signature closes LSU’s class of ESPN 300 additions and marks a strong finish to a hectic first week on the recruiting trail with the Tigers.

Uncertainty surrounding Brown and the program’s top defensive pledges hung over early-week commitments from wide receiver Brayden Allen and former Ole Miss pledges J.C. Anderson (No. 165 in the ESPN 300) and Ryan Miret. Pass catcher Corey Barber, another ex-Rebels commit, also signed with the Tigers on Wednesday. LSU also lost five commitments following Kiffin’s arrival, headlined by safety Dylan Purter (No. 266), who flipped to Florida on Thursday.

Kiffin & Co. took some big swings, as well. Sources tell ESPN that the Tigers made late efforts to flip USC tight end signee Mark Bowman (No. 29 overall) and four-star South Carolina quarterback signee Landon Duckworth (No. 186). LSU also attempted to sway No. 1 wide receiver Chris Henry Jr., who affirmed his pledge to Ohio State and signed Friday.

With Brown officially in the fold, the Tigers will close the early signing period with the nation’s No. 14 signing class in ESPN’s latest class rankings for the cycle.

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