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After just 15 minutes on the streets of Philadelphia’s Kensington neighbourhood, an encounter that was everything. 

It was illustrative of a crisis out of control, it was reflective of a profound personal struggle, it was instructive of the power of addiction, and it was deeply, deeply sad.

“I really didn’t have anybody taking me seriously,” Christophe said to me as he explained why he was where he was.

“I was this young guy, a semi-pro athlete.”

He explained how it had all begun with an injury.

Painkillers, prescribed at first, then self-medicated. Then illicit opioids. Now this new drug, Tranq.

He was fluent, eloquent, thoughtful, and as he told me his truncated life story, he was injecting himself in the left arm.

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It didn’t take long. Seconds. He trailed off. A mumble.

Then nothing. His body stooped.

The hit had hit. He was almost out. He stumbled over to the curb and slumped down. Less than a minute later, he was unconscious.

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Christophe injected Tranq while speaking to Sky News

Stone - Philadelphia
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Christophe slumped to the floor after his hit

I was last here in Philadelphia in February.

We’d gone then to investigate a new street drug which was leaving the most horrific wounds on those who use it. What we found then was shocking, devastating and truly depressing.

I’ve come back now because there’s news that the story of the so-called “zombie drug” has taken a turn.

America’s top drug prevention officials have been analysing nationwide data to see if this new drug, which had first emerged in these Philadelphia streets, is actually more widespread than they had thought.

What they have discovered is alarming.

New analysis of data stretching back to 2019 now shows a jump in Xylazine-related deaths of 276% nationwide. Deaths are more than doubling every year across America.

The drug, a cattle tranquiliser that is mixed by dealers into the existing opioid street drug supply, has now been detected in 48 of the 50 US states. Less than a year ago, they thought it had only been found in Philadelphia.

Regular unadulterated opioids are already killing more than 100,000 Americans every year. So news that xylazine is now so widespread is devastating for users, for volunteers and for the authorities who by our judgment have no control of this crisis.

Read more:
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‘Tranq’ designated ‘threat to the nation’
What is fentanyl?

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Christophe eventually passed out

In Philadelphia, I wanted to see how the users and volunteers I’d met back in February were doing and what they made of a major new “action plan” that President Biden has asked his officials to initiate.

Before Christophe had succumbed to his latest hit, he had seemed encouraged by the news from the White House.

Access to addiction treatment was key, he’d said.

Our guide through these dangerous streets was Ronnie Kaiser, who runs the charity Angels in Motion. She’d shown us around back in February and was keen to do so again.

I watched as she checked on Christophe.

“He has a pulse. He’s not overdosing at the moment,” she said.

The hopelessness here is breathtaking. There are people openly injecting on every street corner; far more than back in February, for sure.

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Ronnie checks Christophe after he injects Tranq

Their addiction is more powerful than the recognition to treat the wounds which appear all over their bodies. Access to treatment – both physical and mental – is so hard. And there is so little in the way of a safety net in America.

“It’s gotten worse,” Ronnie said as we drove past one group of people, all unconscious.

Users must navigate America’s complex and expensive health system if they are to stand a real chance of recovery.

The government’s national plan involves access to prevention, harm reduction treatment and recovery support, as well as bold actions to disrupt the supply from China via Mexico.

“I’m glad they’re finally implementing something. I just hope that the implementation is fast enough and it’s the correct one. Most people here have either mental health or trauma that’s been in their life,” Ronnie told me.

She pointed to the perennial American problem of medical insurance and the “for profit” medical facilities.

“We need federal rehabs, federal recovery houses, the ability for longer rehab stays and definitely all insurances to be accepted at all rehabs,” she said.

Officials in the Biden administration do seem to be recognising the scale of the problem, but now with such profound challenges facing them.

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Dr Rahul Gupta is the White House’s drug policy lead

Joe Biden’s director of national drug control policy, Dr Rahul Gupta, agreed to talk to us.

“On the streets here it looks like failure,” I said to him. “It looks like you have not remotely got a grip of the crisis here in Philadelphia and across the country.”

He conceded: “I think what you’re seeing and what I have seen on the streets of Philadelphia, specifically on Kensington Avenue, is an example of what does happen when we are not implementing those policies.”

“What I’ve seen is so much suffering. A lot of the people do not have homes. A lot of the people need help in an urgent way,” Dr Gupta said.

But he insisted the changes are having an impact: “The policy change that has occurred with prioritising harm reduction, prioritising treatment, meeting people where they are is working.”

Stone - Philadelphia

Christophe took a few minutes to come around. The hits are intense, but they are short and, of course, highly addictive.

“Sorry,” he said. He wanted to finish his story.

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Financial markets were always going to respond to Trump tariffs but they’re also battling with another problem

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Global markets have given Trump a clear no-confidence vote - and his fickleness is making the problem worse

Global financial markets gave a clear vote of no-confidence in President Trump’s economic policy.

The damage it will do is obvious: costs for companies will rise, hitting their earnings.

The consequences will ripple throughout the global economy, with economists now raising their expectations for a recession, not only in the US, but across the world.

Tariffs latest: FTSE 100 suffers biggest daily drop since COVID

Financial investors had been gradually re-calibrating their expectations of Donald Trump over the past few months.

Hopes that his actions may not match his rhetoric were dashed on Wednesday as he imposed sweeping tariffs on the US’ trading partners, ratcheting up protectionism to a level not seen in more than a century.

Markets were always going to respond to that but they are also battling with another problem: the lack of certainty when it comes to Trump.

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He is a capricious figure and we can only guess his next move. Will he row back? How far is he willing to negotiate and offer concessions?

Read more:
There were no winners from Trump’s tariff gameshow
Trade war sparks ‘$2.2trn’ global market sell-off

These are massive unknowns, which are piled on to uncertainty about how countries will respond.

China has already retaliated and Europe has indicated it will go further.

That will compound the problems for the global economy and undoubtedly send shivers through the markets.

Much is yet to be determined, but if there’s one thing markets hate, it’s uncertainty.

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US

Stock markets suffer sharp drops after Donald Trump announces sweeping tariffs

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Stock markets suffer sharp drops after Donald Trump announces sweeping tariffs

Stock markets around the world fell on Thursday after Donald Trump announced sweeping tariffs – with some economists now fearing a recession.

The US president announced tariffs for almost every country – including 10% rates on imports from the UK – on Wednesday evening, sending financial markets reeling.

While the UK’s FTSE 100 closed down 1.55% and the continent’s STOXX Europe 600 index was down 2.67% as of 5.30pm, it was American traders who were hit the most.

Trump tariffs latest: US stock markets tumble

All three of the US’s major markets opened to sharp losses on Thursday morning.

A person works on the floor at the New York Stock Exchange in New York, Monday, March 31, 2025. Pic: AP
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The S&P 500 is set for its worst day of trading since the COVID-19 pandemic. File pic: AP

By 8.30pm UK time (3.30pm EST), The Dow Jones Industrial Average was down 3.7%, the S&P 500 opened with a drop of 4.4%, and the Nasdaq composite was down 5.6%.

Compared to their values when Donald Trump was inaugurated, the three markets were down around 5.6%, 8.7% and 14.4%, respectively, according to LSEG.

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Worst one-day losses since COVID

As Wall Street trading ended at 9pm in the UK, two indexes had suffered their worst one-day losses since the COVID-19 pandemic.

The S&P 500 fell 4.85%, the Nasdaq dropped 6%, and the Dow Jones fell 4%.

It marks Nasdaq’s biggest daily percentage drop since March 2020 at the start of COVID, and the largest drop for the Dow Jones since June 2020.

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The latest numbers on tariffs

‘Trust in President Trump’

White House press secretary Karoline Leavitt told CNN earlier in the day that Mr Trump was “doubling down on his proven economic formula from his first term”.

“To anyone on Wall Street this morning, I would say trust in President Trump,” she told the broadcaster, adding: “This is indeed a national emergency… and it’s about time we have a president who actually does something about it.”

Later, the US president told reporters as he left the White House that “I think it’s going very well,” adding: “The markets are going to boom, the stock is going to boom, the country is going to boom.”

He later said on Air Force One that the UK is “happy” with its tariff – the lowest possible levy of 10% – and added he would be open to negotiations if other countries “offer something phenomenal”.

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How is the world reacting to Trump’s tariffs?

Economist warns of ‘spiral of doom’

The turbulence in the markets from Mr Trump’s tariffs “just left everybody in shock”, Garrett Melson, portfolio strategist at Natixis Investment Managers Solutions in Boston, told Reuters.

He added that the economy could go into recession as a result, saying that “a lot of the pain, will probably most acutely be felt in the US and that certainly would weigh on broader global growth as well”.

Meanwhile, chief investment officer at St James’s Place Justin Onuekwusi said that international retaliation is likely, even as “it’s clear countries will think about how to retaliate in a politically astute way”.

He warned: “Significant retaliation could lead to a tariff ‘spiral of doom’ that could be the growth shock that drags us into recession.”

Read more:
Do Trump’s ‘Liberation Day’ tariff numbers add up?

Tariffs about something more than economics: power

It comes as the UK government published a long list of US products that could be subject to reciprocal tariffs – including golf clubs and golf balls.

Running to more than 400 pages, the list is part of a four-week-long consultation with British businesses and suggests whiskey, jeans, livestock, and chemical components.

Meanwhile, Prime Minister Sir Keir Starmer said on Thursday that the US president had launched a “new era” for global trade and that the UK will respond with “cool and calm heads”.

It also comes as Canadian Prime Minister Mark Carney announced a 25% tariff on all American-imported vehicles that are not compliant with the US-Mexico-Canada trade deal.

He added: “The 80-year period when the United States embraced the mantle of global economic leadership, when it forged alliances rooted in trust and mutual respect and championed the free and open exchange of goods and services, is over. This is a tragedy.”

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Trump’s tariffs are about something more than economics: power

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Trump's tariffs are about something more than economics: power

Tanking stock markets, collapsing world orders, devastating trade wars; economists with their hair ablaze are scrambling to keep up.

But as we try to make sense of Donald Trumps’s tariff tsunami, economic theory only goes so far. In the end this surely is about something more primal.

Power.

Understanding that may be crucial to how the world responds.

Yes, economics helps explain the impact. The world’s economy has after all shifted on its axis, the way it’s been run for decades turned on its head.

Instead of driving world trade, America is creating a trade war. We will all feel the impact.

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PM will ‘fight’ for deal with US

Donald Trump says he is settling scores, righting wrongs. America has been raped, looted and pillaged by the world trading system.

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But don’t be distracted by the hyperbole – and if you think this is about economics alone, you may be missing the point.

Above all, tariffs give Donald Trump power. They strike fear into allies and enemies, from governments to corporations.

This is a president who runs his presidency like a medieval emperor or mafia don.

It is one reason why since his election we have seen what one statesman called a conga line of sycophants make their way to the White House, from world leaders to titans of industry.

The conga line will grow longer as they now redouble their efforts hoping to special treatment from Trump’s tariffs. Sir Keir Starmer among them.

President Trump’s using similar tactics at home, deploying presidential power to extract concessions and deter dissent in corporate America, academia and the US media. Those who offer favours are spared punishment.

His critics say he seeks a form power for the executive or presidential branch of government that the founding fathers deliberately sought to prevent.

Whether or not that is true, the same playbook of divide and rule through intimidation can now be applied internationally. Thanks to tariffs

Each country will seek exceptions but on Trump’s terms. Those who retaliate may meet escalation.

This is the unforgiving calculus for governments including our own plotting their next moves.

The temptation will be to give Trump whatever he wants to spare their economies, but there is a jeopardy that compounds the longer this goes on.

Read more:
Do Trump’s numbers on tariffs really add up?
Trump hits island home only to penguins with 10% tariffs

Chinese Vice President Han Zheng gestures to Britain's Chancellor of the Exchequer Rachel Reeves following a photo session at the Great Hall of the People in Beijing, Saturday, Jan. 11, 2025. (Florence Lo/Pool Photo via AP)
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Could America’s traditional allies turn to China? Pic: AP

Malcolm Turnbull, the former Australian prime minister who coined the conga line comparison, put it this way: “Pretty much all the international leaders I have seen that have sucked up to Trump have been run over. The reality is if you suck up to bullies, whether it’s global affairs or in the playground, you just get more bullying.”

Trading partners may be able to mitigate the impact of these tariffs through negotiation, but that may only encourage this unorthodox president to demand ever more?

Ultimately the world will need a more reliable superpower than that.

In the hands of such a president, America cannot be counted on.

When it comes to security, stability and prosperity, allies will need to fend for themselves.

And they will need new friends. If Washington can’t be relied on, Beijing beckons.

America First will, more and more, mean America on its own.

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