Aspartame, a sweetener commonly found in diet drinks and chewing gum, has been declared a potential cancer risk by the World Health Organisation (WHO).
The sweetener has been listed as “possibly carcinogenic to humans”.
The International Agency for Research on Cancer (IARC), the WHO’s cancer research arm, said there was “limited evidence” aspartame caused cancer in humans.
“While safety is not a major concern at the doses which are commonly used, potential effects have been described that need to be investigated,” the WHO’s Dr Francesco Branca said.
And giving advice to the public, he added: “If consumers are faced with the decision of whether to take cola with sweeteners or one with sugar, I think there should be a third option considered – which is to drink water instead.”
If there’s limited evidence, why has the WHO made this declaration?
The scale used by the IARC indicates the level of evidence there is for a substance being carcinogenic.
The IARC uses four categories: 1 – causes cancer; 2A – probably causes cancer; 2B – possibly causes cancer and 3 – no evidence available on cancer risk.
Aspartame was classified as 2B, “possibly carcinogenic”, on the basis of limited evidence for cancer in humans (specifically hepatocellular carcinoma, a type of liver cancer).
Other possible 2B carcinogens in the group include aloe vera, bracken ferns, lead and working as a hairdresser.
The scale does not say how much exposure you need to raise your cancer risk – it just identifies the substances as hazards.
Alice Davies, health information manager at Cancer Research UK, told Sky News: “Something being classed as a carcinogen doesn’t tell you how much it could increase the risk of cancer.
“Sometimes there are things that might cause cancer in theory, but in reality the dose that you’re exposed to is too low to increase your risk.
“So, for example, processed meat and smoking are both carcinogens but smoking causes about 54,000 cases of cancer in the UK each year whereas processed meat only causes about 5,400.”
So how much aspartame can I have a day?
This is where another arm of the WHO comes in, the Joint WHO and Food and Agriculture Organisation’s Expert Committee on Food Additives – JECFA for short.
JECFA reviewed the data on aspartame consumption and said adults can safely consume up to 40mg per kilo of body weight.
This does not change the daily limits recommended previously.
That means an adult who weighs 70kg could consume 2,800mg of aspartame a day.
Aspartame is found in drinks including Coke Zero, Diet Coke, Diet Pepsi, Pepsi Max, Sprite Zero and Fanta Zero.
A can of diet drink typically contains about 200mg of aspartame. So a 70kg adult could drink 14 cans without going over the safe daily limit for aspartame.
Image: File pic
What does a carcinogen do to your body?
Cancer is a disease of the cells, and a carcinogen is something that disrupts the way cells work.
A carcinogen might damage the cells themselves or it might damage your DNA, Ms Davies from Cancer Research UK said.
For example, a gene that normally prevents cells from replicating too much could be damaged, leading to cells multiplying uncontrollably.
Do I need to worry about aspartame causing cancer?
Rather than worry about things that might cause cancer, Ms Davies said it is better to address confirmed causes of cancer, such as smoking, alcohol and obesity.
“The most important thing really you can do to reduce your risk of cancer is to not smoke, to keep a healthy weight, have a healthy balanced diet, cut down alcohol and stay physically active.”
The Food Standards Agency (FSA) agrees. It says the JECFA report into aspartame is not something people should worry about, as long as they follow the advice that’s already out there.
Professor Robin May, the FSA’s chief scientific adviser, said: “JECFA’s report supports the FSA’s view that aspartame is safe to consume at current permitted use levels.”
The IARC and WHO will continue to monitor new evidence and encourage independent research groups to develop further studies on the potential association between aspartame and cancer.
The FSA said it welcomed this extra research, calling for “more and better studies” into the potential risks of aspartame consumption.
Donald Trump has said that his 28-point peace plan for Ukraine is “by far” not the “final offer”, ahead of crisis talks in Geneva.
Meeting on the sidelines of a G20 summit in South Africa, European and other Western leaders scrambled to respond to the US president’s demand for Ukraine to accept the plan drawn up by the Trump administration and the Kremlin.
In a joint statement on Saturday, they said the plan announced on Friday could serve as a basis for talks to end Russia’s war in Ukraine but required “additional work”.
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As a result, a meeting has been hastily convened in Geneva, Switzerland, on Sunday, where national security advisers from the E3 – France, Britain and Germany – will meet EU, US and Ukrainian officials for further discussions.
Ahead of the talks, Volodymyr Zelenskyy said in a video address to his nation that Ukrainian representatives at the talks “know how to protect Ukrainian national interests and exactly what is needed to prevent Russia from carrying out” another invasion.
“Real peace is always based on security and justice,” the Ukrainian leader added.
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3:08
PM: ‘More to do’ on US Ukraine peace plan
The 28-point peace plan closely resembles the list of demands repeatedly stated by the Kremlin since it launched its full-scale invasion of Ukraine nearly four years ago and if adopted, would see Ukraine cede territory to Russia – and cut the size of its military.
Mr Trump has said he wants a response from Ukraine by Thursday, while suggesting an extension could be possible.
On Saturday, Mr Trump told reporters outside the White House that the plan was not the “final offer” when asked.
He said: “We’d like to get the peace, it should’ve happened a long time ago. The Ukraine war with Russia should’ve never happened. If I was president, it would have never happened. We’re trying to get it ended. One way or another, we have to get it ended.”
His secretary of state Marco Rubio insisted that the peace proposal was authored by the US, despite what a handful of senators have alleged.
“It is based on input from the Russian side. But it is also based on previous and ongoing input from Ukraine,” he said.
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3:42
The 28-point peace plan explained
Leaders have sought to balance praise for President Trump’s attempt to end the war with recognition that some terms in his proposal are unpalatable for Kyiv.
“There are many things that cannot simply be an American proposal, which requires broader consultation,” French President Emmanuel Macron said on the sidelines of the G20, adding that an agreement had to allow for peace for Ukrainians and “security for all Europeans”.
German Chancellor Friedrich Merz underlined the importance to Europe of supporting Ukraine.
“If Ukraine loses this war and possibly collapses, it will have an impact on European politics as a whole, on the entire European continent. And that is why we are so committed to this issue,” he said.
“There is currently an opportunity to end this war, but we are still quite a long way from a good outcome for everyone.”
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0:48
Keir Starmer calls for growth plan at G20
Prime Minister Sir Keir Starmer told reporters in Johannesburg: “We are concerned about [caps on military], because it’s fundamental that Ukraine has to be able to defend itself if there’s a ceasefire.”
He said the proposal “requires additional work”, adding: “And that’s why there’s been the agreement that in Geneva tomorrow [Sunday], you’ll have senior US personnel, you’ll have European NSAs [national security advisers], including the UK NSA, and obviously Ukrainians there to work further on the draft.”
Sir Keir also spoke to Mr Trump, relaying discussions held at G20 to the US leader, according to a Downing Street spokesperson, who added that the two leaders would speak again on Sunday.
“The G20 has worked together before to fix fundamental problems in the global economy. We need to find ways to play a constructive role again today in the face of the world challenges,” he said.
“I’d like to see us come together around a five-point plan for growth that leaves no one behind.”
Image: Sir Keir Starmer, Emmanuel Macron and Friedrich Merz at the G20 summit. Pic: PA
The US, however, is boycotting the talks.
The Trump administration made its opposition to South Africa’s G20 agenda clear earlier this year when the country started holding meetings ahead of the summit. South Africa gets to set the agenda as the country holding the rotating G20 presidency.
G20 leaders broke with tradition and adopted a declaration at the start of their summit – despite opposition from the US.
Vincent Magwenya, spokesman for South African president Cyril Ramaphosa, said a leaders’ declaration was adopted unanimously in Johannesburg.
The White House later accused South Africa of refusing to facilitate a smooth transition of the G20 presidency.
The G20 bloc was formed in 1999 as a bridge between rich and poor nations to confront global financial crises.
While it often operates in the shadow of the powerful Group of Seven nations, G20 members represent around 85% of the world’s economy, 75% of international trade and more than half the global population.
Countries attending COP30, the biggest climate meeting of the year, have agreed steps to help speed up climate action, according to a draft deal.
The meeting of leaders in the Brazilian city of Belem also saw them agree to reviewing related trade barriers and triple the money given to developing countries to help them withstand extreme weather events, according to the draft.
However, the summit’s president Correa do Lago said “roadmaps” on fossil fuels and forests would be published as there was no consensus on these issues.
The annual United Nations conference brings together world leaders, scientists, campaigners, and negotiators from across the globe, who agree on collective next steps for tackling climate change.
The two-week conference in the Amazon city of Belem was due to end at 6pm local time (9pm UK time) on Friday, but it dragged into overtime.
The standoff was between the EU, which pressed for language on transitioning away from fossil fuels, and the Arab Group of nations, including major oil exporter Saudi Arabia, which opposed it.
The impasse was resolved following all-night negotiations led by Brazil, negotiators said.
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The European Union’s climate commissioner, Wopke Hoekstra, said on Saturday that the proposed accord was acceptable, even though the bloc would have liked more.
“We should support it because at least it is going in the right direction,” he said.
The Brazilian presidency scheduled a closing plenary session.
Brazil’s President Luiz Inacio Lula da Silva and about 80 countries, including the UK and coal-rich Colombia, had been pushing for a plan on how to “transition away from fossil fuels”.
This is a pledge all countries agreed to two years ago at COP28 – then did very little about since.
But scores of countries – including major oil and gas producers like Saudi Arabia and Russia – see this push as too prescriptive or a threat to their economies.
This breaking news story is being updated and more details will be published shortly.
Israel says it has begun striking Hamas targets in Gaza, reportedly killing at least nine people, after what it called a “blatant violation of the ceasefire agreement”.
Local health authorities in Gaza said there had been three separate airstrikes, one hit a car in the densely populated Rimal neighbourhood, killing five people and wounding several others.
Shortly after the attack on the car, the Israeli air force hit two more targets in the central Gaza Strip, medics said.
They said at least four people died when two houses were struck in Deir Al-Balah city and Nuseirat camp.
The Israeli military said there had been a “blatant violation of the ceasefire agreement”.
It claimed a gunman had crossed into Israeli-held territory after exploiting “the humanitarian road in the area through which humanitarian aid enters southern Gaza”.
A Hamas official rejected the Israeli military’s allegations as baseless, calling them an “excuse to kill”, adding the Palestinian group was committed to the ceasefire agreement.
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The Israeli airstrikes are a further test of a fragile ceasefire with Hamas, which has held since 10 October following the two-year Gaza war.
Israel pulled back its troops, and the flow of aid into the territory has increased. But violence has not completely halted.
Palestinian health authorities say Israeli forces have killed 316 people in strikes on Gaza since the truce.
Meanwhile, Israel says three of its soldiers have been killed since the ceasefire began and it has attacked scores of militants.
This breaking news story is being updated and more details will be published shortly.