Connect with us

Published

on

UK scientists have begun developing vaccines as an insurance against a new pandemic caused by an unknown “Disease X”.

The work is being carried out at the government’s high-security Porton Down laboratory complex in Wiltshire by a team of more than 200 scientists.

They’ve drawn up a threat list of animal viruses that are capable of infecting humans and could in future spread rapidly around the world.

Which of them will break through and trigger the next pandemic is unknown, which is why it’s referred to only as “Disease X.”

Sky News was escorted around the site, which is run by the UK Health Security Agency, to see the work being done in high-containment labs.

Professor Dame Jenny Harries, the head of the UKHSA.
Image:
Professor Dame Jenny Harries, the head of the UKHSA

Professor Dame Jenny Harries, the head of the UKHSA, told Sky News: “What we’re trying to do here is ensure that we prepare so that if we have a new Disease X, a new pathogen, we have done as much of that work in advance as possible.

“Hopefully we can prevent it [a pandemic]. But if we can’t and we have to respond, then we have already started developing vaccines and therapeutics to crack it.”

The Vaccine Development and Evaluation Centre at Porton Down has been expanded to take on the work.

Originally, it was focussed on COVID and testing the effectiveness of vaccines against new variants.

But scientists at the centre are now involved in monitoring several high-risk pathogens, including bird flu, monkeypox and hantavirus, a disease spread by rodents.

File photo dated 25/02/21 of the Dstl high containment lab building at Porton Down in Salisbury, Wiltshire
Image:
File photo of a high containment lab at Porton Down

One early success is the world’s first vaccine against Crimean-Congo haemorrhagic fever, a disease that’s spread by ticks and has a fatality rate of 30%.

Early stage clinical trials have just started, with 24 volunteers expected to test the jab.

The disease is becoming more common in Europe as global temperatures rise and some travellers have returned to the UK with the infection.

Read more:
COVID-19 potentially ‘spread from deer to humans multiple times’
Nicola Sturgeon admits there was ‘no plan’ to deal with pandemic

UK scientists have begun developing vaccines as an insurance against a new pandemic caused by an unknown ‘Disease X’. The work is being carried out at the government’s high-security Porton Down laboratory complex in Wiltshire by a team of more than 200 scientists.

Prof Harries said climate change and population shifts are making another pandemic more likely.

“What we’re seeing is a rising risk globally,” she said.

“Some of that is because of things like urbanisation where you may get virus jumping into humans [living close-by], as we’ve seen with bird flu.

“And some of it is because of climate change where you get things like ticks and mosquitoes moving to where it was previously cold and is now becoming increasingly warm.

“So this is a growing risk agenda. But it’s one we can use our science actively to prevent human impact.”

Click to subscribe to the Sky News Daily wherever you get your podcasts

Bird flu is currently thought to be the most likely pandemic threat.

The Royal Society for the Protection of Birds says at least 30,000 seabirds have died around the UK this summer as a more virulent strain of the H5N1 virus has swept around the world.

There is also evidence of limited spread in some mammals.

Bird flu is currently thought to be the most likely pandemic threat. The RSPB says at least 30,000 seabirds have died around the UK this summer as a more virulent strain of the H5N1 virus has swept around the world.
Image:
Bird flu is currently thought to be the most likely pandemic threat

And four people working on poultry farms in the UK have also tested positive, but were only mildly affected.

The UKHSA has started monitoring people in close contact with birds in case it can spread without causing symptoms.

The agency is part of a global effort to develop a vaccine within 100 days of a new pathogen being recognised as having pandemic potential.

“Historically, that would be unheard of,” said Prof Harries.

“It would normally take five or 10 years. For COVID it was around 360 days.

“So this is a really high ambition. But for some viruses, it is definitely possible.”

Continue Reading

UK

Manchester United legend Denis Law dies aged 84

Published

on

By

Manchester United legend Denis Law dies aged 84

Former Manchester United and Scotland footballer Denis Law has died, at the age of 84.

In a statement, his family said: “It is with a heavy heart that we tell you our father Denis Law has sadly passed away. He fought a tough battle, but finally, he is now at peace.

“We would like to thank everyone who contributed to his wellbeing and care, past and much more recently.

“We know how much people supported and loved him and that love was always appreciated and made the difference.”

Denis Law in 2005. Pic: PA
Image:
Denis Law in 2005. Pic: PA

The Aberdeen-born footballer previously announced in August 2021 that he had been diagnosed with dementia.

A prolific striker, Law scored 237 goals in 404 appearances for Manchester United, for whom he signed for a then-British record transfer fee in 1962.

He is the only man to have two statues dedicated to him at Old Trafford – one on the Stretford End concourse, the other as part of the United Trinity statue overlooking the stadium’s forecourt beside fellow great George Best and Sir Bobby Charlton.

Denis Law, third from left, as a statue featuring him alongside Sir Bobby Charlton and George Best - known as the 'holy trinity' was unveiled in 2008.
Image:
Denis Law, third from left, as a statue featuring him alongside Sir Bobby Charlton and George Best – known as the ‘holy trinity’ – was unveiled in 2008. Pic: AP

The only Scottish player to have won the Ballon d’Or award, in 1964, he was also part of United’s triumphant campaign in the 1968 European Cup – in which they became the first English club to ever win the competition.

In a statement, the club said: “Everyone at Manchester United is mourning the loss of Denis Law, the King of the Stretford End, who has passed away, aged 84.

“He will always be celebrated as one of the club’s greatest and most beloved players.

Denis Law, centre, during Manchester United's triumphant European Cup campaign in 1968. Pic: AP
Image:
Denis Law, centre, during Manchester United’s triumphant European Cup campaign in 1968. Pic: AP

“The ultimate goalscorer, his flair, spirit and love for the game made him the hero of a generation. Our deepest condolences go out to Denis’s family and many friends. His memory will live on forever more.”

Wayne Rooney, former United captain and the club’s all-time record goalscorer, described Law as a “legend”.

“Thoughts with all Denis’s family and friends,” he said in an online post.

Another former United captain, Gary Neville, said: “A great footballer and a great man. It’s a privilege and an honour to have spent time in your company. The King of the Stretford End.”

A tribute from the Scotland national team said Law was “a true great”.

“We will not see his likes again,” it said.

Law also played for Huddersfield Town, Manchester City, and Italian club Torino during his club career, and made 55 appearances for Scotland, scoring 30 goals for his country.

Manchester City said in a post on X: “The whole of Manchester, including everyone at City, is mourning with you. Rest in peace, Denis.”

Continue Reading

UK

FTSE 100 closes at record high

Published

on

By

FTSE 100 closes at record high

The UK’s benchmark stock index has reached another record high.

The FTSE 100 index of most valuable companies on the London Stock Exchange closed at 8,505.69, breaking the record set last May.

It had already broken its intraday high at 8532.58 on Friday afternoon, meaning it reached a high not seen before during trading hours.

Money blog: Major boost for mortgage holders

The weakened pound has boosted many of the 100 companies forming the top-flight index.

Why is this happening?

Most are not based in the UK, so a less valuable pound means their sterling-priced shares are cheaper to buy for people using other currencies, typically US dollars.

This makes the shares better value, prompting more to be bought. This greater demand has brought up the prices and the FTSE 100.

The pound has been hovering below $1.22 for much of Friday. It’s steadily fallen from being worth $1.34 in late September.

Also spurring the new record are market expectations for more interest rate cuts in 2025, something which would make borrowing cheaper and likely kickstart spending.

What is the FTSE 100?

The index is made up of many mining and international oil and gas companies, as well as household name UK banks and supermarkets.

Familiar to a UK audience are lenders such as Barclays, Natwest, HSBC and Lloyds and supermarket chains Tesco, Marks & Spencer and Sainsbury’s.

Other well-known names include Rolls-Royce, Unilever, easyJet, BT Group and Next.

Read more:
Russia sanctions: Fears over UK enforcement by HMRC
Trump tariff threat prompts IMF warning ahead of inauguration

FTSE stands for Financial Times Stock Exchange.

If a company’s share price drops significantly it can slip outside of the FTSE 100 and into the larger and more UK-based FTSE 250 index.

The inverse works for the FTSE 250 companies, the 101st to 250th most valuable firms on the London Stock Exchange. If their share price rises significantly they could move into the FTSE 100.

A good close for markets

It’s a good end of the week for markets, entirely reversing the rise in borrowing costs that plagued Chancellor Rachel Reeves for the past ten days.

Fears of long-lasting high borrowing costs drove speculation she would have to cut spending to meet self-imposed fiscal rules to balance the budget and bring down debt by 2030.

Please use Chrome browser for a more accessible video player

They Treasury tries to calm market nerves late last week

Long-term government borrowing had reached a high not seen since 1998 while the benchmark 10-year cost of government borrowing, as measured by 10-year gilt yields, was at levels last seen around the 2008 financial crisis.

The gilt yield is effectively the interest rate investors demand to lend money to the UK government.

Only the pound has yet to recover the losses incurred during the market turbulence. Without that dropped price, however, the FTSE 100 record may not have happened.

Also acting to reduce sterling value is the chance of more interest rates. Currencies tend to weaken when interest rates are cut.

Continue Reading

UK

Nazi-obsessed terrorist Callum Parslow jailed after trying to murder asylum seeker at Worcestershire hotel

Published

on

By

Nazi-obsessed terrorist Callum Parslow jailed after trying to murder asylum seeker at Worcestershire hotel

A Nazi-obsessed man has been jailed for attempted murder after he stabbed an asylum seeker in a terrorist attack.

Callum Parslow was handed a life sentence and will serve a minimum of 22 years and eight months in prison after he knifed the man at a Worcestershire hotel on 2 April last year, as a “protest” against small boat crossings.

The victim, Nahom Hagos, from Eritrea, said it was a “miracle” he survived after being stabbed in the chest and hand.

Parslow, 32, has Hitler’s signature tattooed on his arm and used a £770 knife he had bought online to attack Mr Hagos when he was eating in the conservatory of the Pear Tree Inn at Hindlip.

During sentencing, the judge, Mr Justice Dove, told Parslow: “You committed a vicious and unprovoked assault on a complete stranger Nahom Hagos who suffered devastating injuries as a result of your violence.”

The judge also said Parslow, from Worcester, was “motivated by your adoption of a far-right neo-Nazi mindset which fuelled your warped, violent and racist views”, and added: “This was undoubtedly a terrorist attack.”

He was found guilty of attempted murder in October last year.

More on Hate Crime

Callum Parslow. 
Pic: West Midlands Police/PA
Image:
Callum Parslow. Pic: West Midlands Police/PA

Leicester Crown Court heard at the time that Mr Hagos, who used to live at the hotel, was visiting a friend and was stabbed after Parslow asked him for directions to the toilet.

CCTV from the scene showed Mr Hagos fleeing to a car park and being chased by Parslow. He was able to run back into the main reception area, where the hotel manager locked the front door.

Parslow later re-entered through another door apparently searching for further victims, the court heard.

The hotel manager and a builder used a van to take Mr Hagos to hospital in Worcester, as they felt he was losing too much blood, where he was found to have an 8cm-long wound which had not penetrated any of his vital organs.

After trying to kill Mr Hagos, Parslow ran towards a canal and was spotted with what appeared to be blood on his hands.

Officers found blood containing a DNA profile matching that of the victim on the blade of the knife abandoned by Parslow.

The knife belonging to Callum Ulysses Parslow.
Pic: West Midlands Police/PA
Image:
The knife belonging to Parslow. Pic: West Midlands Police/PA

Failed manifesto post

After the stabbing and as police closed in, Parslow tried to post a “terrorist manifesto” on X, tagging Tommy Robinson and politicians including Nigel Farage, Suella Braverman and Sir Keir Starmer.

He wrote that he “just did my duty to England” and had tried to “exterminate” Mr Hagos. However, it failed to send as he copied in too many people.

Others on his list included Laurence Fox, Lee Anderson, Boris Johnson, Donald Trump and various news organisations.

Nazi memorabilia at bedsit

During the trial last October, the court heard an axe, metal baseball bat and a second knife were found at Parslow’s bedsit in Bromyard Terrace in Worcester.

Police also discovered a swastika armband, a Nazi-era medallion and copies of Hitler’s book Mein Kampf.

Nazi memorabillia seized at the bedsit of Callum Parslow in Worcester. 
Pic:West Midlands Police/PA
Nazi memorabillia seized at the bedsit of Callum Ulysses Parslow in Worcester.  
Pic: West Midlands Police/PA
Image:
Nazi memorabilia which was seized at Parslow’s bedsit in Worcester. Pics: West Midlands Police/PA

Jurors were also told Parslow had Hitler’s signature tattooed on his arm “in order to demonstrate his affiliation to the ideals of the leader of the German Nazi party”.

He also pleaded guilty to an unconnected sexual offence and two charges of sending electronic communications with intent to cause distress and anxiety at the time.

Read more from Sky News:
Heart Breakfast’s Jamie Theakston reveals he’s cancer free
Tesla Cybertruck seized after being unlawfully driven

‘The pain feels unbearable’

Mr Hagos told the court in an impact statement he continues to feel “excruciating pain” in his hand after the attack by Parslow.

Read out by the prosecution on Friday, he said: “The pain is unbearable and keeps me awake all night long.

“The pain feels like an electric shock going through my hand and I now have insomnia.”

He then said he had been “living and pursuing a happy life before the incident,” but added: “I feel lonely and don’t feel safe on the street.

“My life has been turned upside down.”

Continue Reading

Trending