UK’s first-ever womb transplant hailed by doctors as ‘dawn of new era’ in fertility treatment
The first-ever womb transplant in the UK has been hailed as the “dawn of a new era” in fertility treatment.
A 40-year-old woman, who already had two children, decided to help her 34-year-old sister, who had been born without a uterus.
Now, six months on, the recipient is having periods and is preparing to eventually have her own embryos implanted, already created via IVF with her own eggs.
Pic: Womb Transplant UK
Professor Richard Smith, one of two lead surgeons during the operations, said it had been a “massive success”, describing the joy he shared with the sisters during a clinic one month on.
“We were all in tears – it was a very, very emotional,” he said.
“I think it was probably the most stressful week of our surgical careers, but also unbelievably positive.
“The donor and recipient are just over the moon.”
The recipient lives in England, and she and her sister do not wish to be named.
The surgery was carried out one Sunday in early February at Oxford’s Churchill Hospital by a team of more than 30 staff.
The operation to remove the donor’s womb lasted more than eight hours.
Pic: Womb Transplant UK
Before the uterus was taken out, surgeons had already begun operating on her younger sister and after a further nine hours and 20 minutes, the transplant was complete.
The surgery was funded by Womb Transplant UK at a cost of £25,000, which included paying the NHS for theatre time and the patients’ hospital stay.
Surgeons and medical staff were not paid for their time.
“I’m just really happy that we’ve got a donor, who is completely back to normal after her big op, and the recipient is… doing really well on her immunosuppressive therapy and looking forward to hopefully having a baby,” said Prof Smith, who is the charity’s clinical lead.
The transplant is expected to last for a maximum of five years before the womb will be removed.
‘Remarkable achievement’
The chair of the British Fertility Society, Dr Raj Mathur, described it as “a remarkable achievement”.
“I think it’s the dawn of a new age, a new era in treating these patients,” said the consultant gynaecologist.
“You have got to remember some of these patients are the most difficult fertility situations that you can imagine – they are either born without a uterus or they have lost the uterus for reasons of cancer or other problems, for instance in labour.
“Up until now we have really not had any way of helping them other than surrogacy.”
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Isabel Quiroga, consultant surgeon at the Oxford Transplant Centre, and fellow lead during the operations, said they had been ready to attempt the first transplant before the pandemic.
“We are just delighted that this day had come,” she said.
“The whole team worked extremely well – it was an incredibly proud moment.”
The surgical team. Pic: Womb Transplant UK
For now, the plan is to focus on living donations from a relative with up to 30 transplants a year, but many women have come forward to offer their wombs.
“We have women contacting the charity… such as young women who say: ‘I don’t want to have children, but I would love to help others have a child’ or ‘I’ve already had my children I would love other women to have that experience’,” said Miss Quiroga.
Other countries, including Sweden and US, have already carried out womb transplants, ultimately resulting in successful births.
A second UK womb transplant on another woman is scheduled to take place this autumn, with more patients in the preparation stages.
Spring sunshine will return to parts of the UK in time for Mother’s Day and continue into next week – potentially bringing the hottest day of the year so far, forecasters have said.
Sky weather producer Kirsty McCabe said Mothering Sunday was likely to be a “mostly fine day with bright or sunny spells once early low cloud and drizzle clears”.
She predicted there would be “temperatures near or above average” for most places.
Afterwards, however, high pressure is set to dominate. There is a good chance the highest temperature of the year so far will be reached by the middle of next week, topping the high of 21.3C (70F) recorded on 20 March.
However, the far north and west of the British Isles are likely to be cloudier and windier with a risk of rain.
The Met Office has also forecast that warm conditions will return on Sunday after a brief, changeable period in what it called “typical spring fashion”.
Central and inland areas should have the warmest weather on Mother’s Day, with its forecasters also predicting “a short-lived spell of unsettled weather this weekend”.
A woman enjoys the warmer weather in London’s Green Park. Pic: PA
But the Met Office added the country would “transition back towards a blocked weather pattern as high pressure builds on Sunday and dominates our weather through much of next week”.
Honor Criswick, a meteorologist from the agency, said the high pressure would “stick around as we head into next week, bringing some fine and settled conditions, perhaps even some warm sunshine”.
Partial solar eclipse in parts of UK
Ms Criswick said Sunday morning would be cloudy, with possible drizzle and mist, but that would give way to a dry day with “some sunny spells, particularly across central and inland areas of the UK”.
She predicted there would be “quite a settled start to the week next week, lots of sunny spells and also some quite warm temperatures”.
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Meanwhile, a partial solar eclipse will be visible in parts of the UK between 10am and noon on Saturday.
Those in the east of the country will have the best chance of seeing it.
The phenomenon occurs when the moon passes between the sun and the Earth. However, the three planetary bodies will not be completely aligned, meaning only part of the sun will be obscured this weekend.
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