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Breakups are not much fun.

Whether it’s your first time through it or an unfortunate familiarity, there are few more agonising gut punches.

Doubts and insecurities aplenty; wondering where, how and why things changed; and like an agonising Lionesses World Cup run, an overwhelming sense of “what if”.

Being a “science and tech journalist” has given me a fresh perspective on how it can impact us physically.

Where’s that headache come from? What about a sudden lack of energy? And why does eating anything, even a normal favourite, feel like an I’m A Celebrity challenge?

For when pictures of wistful poetry on Instagram just don’t cut it, it turns out science has some answers.

The holy trinity

As neuroscientist Dr Lucy Brown puts it, “we’re all miserable when we’ve been dumped” – and there’s a potent chemical cocktail that helps explain why.

Serotonin is the brain chemical associated with happiness, oxytocin with bonding, and dopamine gets pumped out whenever your mind’s reward system kicks in.

No surprise then that you feel good when that holy trinity is high and rough when it’s low.

The key chemical is dopamine: the ultimate natural drug.

‘It’s like we’re addicted’

Brown was one of a team of researchers who conducted a study into the impact of heartbreak, scanning the brain activity of 15 young adults who were going through unwanted breakups.

They were shown photos of their ex-partners, and the scans showed parts of the brain that power our sense of motivation and reward – where our dopaminergic neurons live – went into overdrive.

It’s an “overactivity” Brown compares to what you’d see in a cocaine addict trying to wean themselves off.

“It’s like we’re addicted to each other,” she says.

“When we lose someone, we’ve lost a very rewarding part of our lives and sense of self. They’ve provided novelty in your life that now isn’t there, so we need some other rewards.”

And like rewatching goals we may have thought had put the Lionesses’ name on the title, looking back at texts and holiday photos won’t do the trick.

Pic: AP
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Maybe next time… Pic: AP

A body under threat

Florence Williams had found herself intrigued by the pain her heartbreak caused.

Having seen her 25-year marriage suddenly fall apart, trauma was expected. But feeling physically sick and totally overwhelmed took her by surprise.

“I was of course stunned by the event itself, but then I was really confused and surprised by how different I felt physically going through it,” she says.

“That feeling of being plugged into a faulty electrical socket; this buzzing sense of background anxiety and hypervigilance and an inability to sleep well; the weight loss and general confusion.

“My body felt under threat.”

Williams’s experience and sense of confusion sent her on a global quest for answers documented in her book, Heartbreak: A Personal And Scientific Journey.

She found while everyone’s personal heartbreak is different, the bodily response is much the same: it’s time for that holy trinity of hormones to take a battering.

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Florence Williams. Pic: Casie Zalud
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Florence Williams. Pic: Casie Zalud

‘Very real’ physical symptoms

And it’s not just emotional pain you may struggle with. In Brown’s study, brain areas associated with physical pain were also activated.

She explains rejection triggers a part of the brain called the insular cortex – the same part that responds to distress around pain, like when panic sets in after an already painful bee sting.

When emotional stress causes physical symptoms, like headaches and nausea, its medical term is somatisation.

“If you’ve ever had butterflies when you’ve been nervous, you’ve experienced this,” explains Dr Abishek Rolands.

“The most important thing to remember is even though there is no physical cause, the symptoms are very real – they are not made up or ‘all in the head’.”

During her research, Williams, who has two adult children with her ex-husband, was particularly fascinated by the impact loss can have on our immune system.

“It’s important for our nervous systems that we feel safe,” she says.

“If we have people in our lives triggering cascades of healthy hormones, it’s really protective against illness. Our cells actually listen to our mental state.”

Indeed, previous studies have stressed the importance of meaningful social relationships to stay healthy.

And in 2021, US researchers suggested our immune system takes cues from our nervous system if it’s struggling – effectively making decisions that could make us sick.

Depressed man suffering from insomnia lying in bed

Broken heart syndrome

In rare cases, this kind of emotional distress – especially when delivered suddenly – can even lead to the fittingly nicknamed “broken heart syndrome” – or takotsubo cardiomyopathy.

Sindy Jodar, a senior cardiac nurse at the British Heart Foundation, says the symptoms – chiefly shortness of breath and chest pain – are consistent with a heart attack.

“Most people have either been under a lot of physical or emotional stress, like losing a loved one,” she says.

“The only explanation we have at the moment is when the body is stressed, it releases a lot of catecholamines (adrenaline), and when lots of that is around in the body it can impact the heart.”

Unlike a heart attack, the condition does not cause blockages in the coronary arteries – but does totally change the shape of the heart’s left ventricle, which pumps oxygenated blood through the body.

It’s this which gives the condition its actual Japanese name, as the shape of the ventricle becomes reminiscent of a trap fishermen use to catch octopus: narrow at the top, larger at the bottom.

The condition only impacts around 5,000 people a year in the UK, and is more common in menopausal women, with most recovering after a few weeks.

A study has said that cognitive decline accelerates after heart attack. Pic: iStock
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The condition’s symptoms are consistent with a heart attack

Giving up the addiction

Just as science can explain why heartbreak, rejection, and loss makes us feel the way we do, it also offers solutions.

Brown says heartbreak should be treated like “having to give up an addiction”, though she admits the “craving is stronger when we’ve lost someone”.

But there are plenty of roads to go down without gorging ice cream while watching La La Land.

Williams stresses the importance of working to activate the parasympathetic part of your nervous system by doing things that make you feel calm. The other part of our autonomic nervous system, sympathetic, is what causes anxiety and hypervigilance.

“Connection to nature is really calming,” she says, likewise to friends and family. “And there’s lots of data showing the more meaning you derive from work, the more purpose you feel, the happier you’ll be.”

Williams says such lessons apply to anyone “going through an emotional life quake”.

“People who end a relationship also face big emotions – guilt, sadness, loneliness,” she adds.

A woman walking past daffodils in St James's Park, London. Picture date: Thursday April 6, 2023.
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Walks in nature are great for clearing your mind

And as Brown says, there’s novelty – that sense of excitement that needs refreshing in a healthy, sustainable way.

Ice cream makes a compelling dinner once, but you’d probably best hope it wears off.

“A good strategy is beginning things you didn’t do during a relationship, like running or travelling,” says Brown.

“People always remember a heartbreak – it’s very painful. But you do change, and can for the better.”

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North Korea’s opened its doors to Russian tourists. So… how was their holiday?

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North Korea's opened its doors to Russian tourists. So... how was their holiday?

The world’s most secretive state is a mystery for billions of people – but not Anastasiya Samsonova.

She has returned from a week’s holiday in North Korea.

“We saw nothing terrible there, there is no danger there,” the 33-year-old HR manager tells me.

“Frankly speaking, we really liked it.”

She was part of a group of 15 Russian tourists who were the first foreign visitors to a new seaside resort, which was opened to great fanfare by North Korea’s leader Kim Jong Un in June.

Her holiday snaps show a white sand beach, shimmering seas and high-rise hotels. But something’s missing – people.

Russian tourist Anastasiya Samsonova at the Wonsan-Kalma beach resort in North Korea. Pic: Anastasiya Samsonova
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Anastasiya Samsonova at the Wonsan-Kalma beach resort in North Korea. Pic: Anastasiya Samsonova

There are rows of sun loungers, but not a soul sitting on them. A glittering banquet hall that’s devoid of diners.

That’s because, when it comes to international tourists, the Wonsan-Kalma resort is currently only open to Russians.

“The hotel was absolutely new,” Anastasiya enthuses, unfussed by the absence of others.

“Everything was done very beautifully, a good interior … very developed infrastructure.”

Russian tourist Anastasiya Samsonova enjoying a meal on a train in North Korea. Pic: Anastasiya Samsonova
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Pic: Anastasiya Samsonova

But why not Turkey? Or Thailand?

I gently suggest that people in Britain might be shocked at the idea of a summer break in a country better known for famines and forced labour than parasols and pina coladas.

“We were interested in seeing how people live there,” Anastasiya explains.

“There were a lot of prejudices about what you can and can’t do in North Korea, how you can behave. But actually, we felt absolutely free.”

Russian tourist Anastasiya Samsonova reading a North Korean newspaper. Pic: Anastasiya Samsonova
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Pic: Anastasiya Samsonova

Anastasiya is one of a growing number of Russians who are choosing to visit their reclusive neighbour as the two allies continue to forge closer ties following the Kremlin’s invasion of Ukraine.

Last year, North Korean troops supplied military support in Russia’s Kursk region, and now there is economic cooperation too.

North Korean produce, including apples and beer, has started appearing on supermarket shelves in Russia’s far east.

And last month, Moscow launched direct passenger flights to Pyongyang for the first time in decades.

North Korean apples on sale in Russia. Pic: Danil Biryukov / DVHAB.RU
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Pic: Danil Biryukov / DVHAB.RU

But can this hermit nation really become a holiday hotspot?

The Moscow office of the Vostok Intur travel agency believes so. The company runs twice-weekly tours there, and I’m being given the hard sell.

“North Korea is an amazing country, unlike any other in the world,” director Irina Kobeleva gushes, before listing some unusual highlights.

“It is a country where you will not see any advertising on the streets. And it is very clean – even the asphalt is washed.”

She shows me the brochures, which present a glossy paradise. There are images of towering monuments, pristine golf greens and immaculate ski slopes. But again, no people.

Irina Kobeleva, director of Vostok Intur travel's Moscow office
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‘There is a huge growing demand among young people,’ Irina Kobeleva says

Ms Kobeleva insists the company’s tours are increasingly popular, with 400 bookings a month.

“Our tourists are mostly older people who want to return to the USSR,” she says, “because there is a feeling that the real North Korea is very similar to what was once in the Soviet Union.

“But at the same time, there is a huge growing demand among young people.”

Sure enough, while we’re chatting, two customers walk in to book trips. The first is Pavel, a young blogger who likes to “collect” countries. North Korea will be number 89.

“The country has opened its doors to us, so I’m taking this chance,” he tells me when I ask why he wants to go.

Read more from Sky News:
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For pensioner Tatiana, the reason is sentimental.

“My husband wanted to go there, but now he’s gone. So I want his wish to come true,” she says.

It’ll certainly cost them. One week’s trip that takes in Pyongyang, a circus and the new beach resort, costs roughly £1,500 without flights.

At that price, I suspect most tourists will be content for this secretive state to remain hidden.

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US trade war: The state of play as Trump signs order imposing new tariffs – but there are more delays

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US trade war: The state of play as Trump signs order imposing new tariffs - but there are more delays

Donald Trump’s trade war has been difficult to keep up with, to put it mildly.

For all the threats and bluster of the US election campaign last year to the on-off implementation of trade tariffs – and more threats – since he returned to the White House in January, the president‘s protectionist agenda has been haphazard.

Trading partners, export-focused firms, customs agents and even his own trade team have had a lot on their plates as deadlines were imposed – and then retracted – and the tariff numbers tinkered.

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While the UK was the first country to secure a truce of sorts, described as a “deal”, the vast majority of nations have failed to secure any agreement.

Deal or no deal, no country is on better trading terms with the United States than it was when Trump 2.0 began.

Here, we examine what nations and blocs are on the hook for, and the potential consequences, as Mr Trump’s suspended “reciprocal” tariffs prepare to take effect. That will now not happen until 7 August.

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Why was 1 August such an important date?

To understand the present day, we must first wind the clock back to early April.

Then, Mr Trump proudly showed off a board in the White House Rose Garden containing a list of countries and the tariffs they would immediately face in retaliation for the rates they impose on US-made goods. He called it “liberation day”.

The tariff numbers were big and financial markets took fright.

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What does the UK-US trade deal involve?

Just days later, the president announced a 90-day pause in those rates for all countries except China, to allow for negotiations.

The initial deadline of 9 July was then extended again to 1 August. Late on 31 July, Mr Trump signed the executive order but said that the tariff rates would not kick in for seven additional days to allow for the orders to be fully communicated.

Since April, only eight countries or trading blocs have agreed “deals” to limit the reciprocal tariffs and – in some cases – sectoral tariffs already in place.

Who has agreed a deal over the past 120 days?

The UK, Japan, Indonesia, the European Union and South Korea are among the eight to be facing lower rates than had been threatened back in April.

China has not really done a deal but it is no longer facing punitive tariffs above 100%.

Its decision to retaliate against US levies prompted a truce level to be agreed between the pair, pending further talks.

There’s a backlash against the EU over its deal, with many national leaders accusing the European Commission of giving in too easily. A broad 15% rate is to apply, down from the threatened 30%, while the bloc has also committed to US investment and to pay for US-produced natural gas.

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Millions of EU jobs were in firing line

Where does the UK stand?

We’ve already mentioned that the UK was the first to avert the worst of what was threatened.

While a 10% baseline tariff covers the vast majority of the goods we send to the US, aerospace products are exempt.

Our steel sector has not been subjected to Trump’s 50% tariffs and has been facing down a 25% rate. The government announced on Thursday that it would not apply under the terms of a quota system.

UK car exports were on a 25% rate until the end of June when the deal agreed in May took that down to 10% under a similar quota arrangement that exempts the first 100,000 cars from a levy.

Who has not done a deal?

Canada is among the big names facing a 35% baseline tariff rate. That is up from 25% and covers all goods not subject to a US-Mexico-Canada trade agreement that involves rules of origin.

America is its biggest export market and it has long been in Trump’s sights.

Mexico, another country deeply ingrained in the US supply chain, is facing a 30% rate but has been given an extra 90 days to secure a deal.

Brazil is facing a 50% rate. For India, it’s 25%.

What are the consequences?

This is where it all gets a bit woolly – for good reasons.

The trade war is unprecedented in scale, given the global nature of modern business.

It takes time for official statistics to catch up, especially when tariff rates chop and change so much.

Any duties on exports to the United States are a threat to company sales and economic growth alike – in both the US and the rest of the world. Many carmakers, for example, have refused to offer guidance on their outlooks for revenue and profits.

Apple warned on Thursday night that US tariffs would add $1.1bn of costs in the three months to September alone.

Barriers to business are never good but the International Monetary Fund earlier this week raised its forecast for global economic growth this year from 2.8% to 3%.

Some of that increase can be explained by the deals involving major economies, including Japan, the EU and UK.

US growth figures have been skewed by the rush to beat import tariffs but the most recent employment data has signalled a significant slowdown in hiring, with a tick upwards in the jobless rate.

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The big risk ahead?

It’s the prospect of another self-inflicted wound.

The elephant in the room is inflation. Countries imposing duties on their imports force the recipient of those goods to foot the additional bill. Do the buyers swallow it or pass it on?

The latest US data contained strong evidence that tariff charges were now making their way down the country’s supply chains, threatening to squeeze American consumers in the months ahead.

It’s why the US central bank has been refusing demands from Mr Trump to cut interest rates. You don’t slow the pace of price rises by making borrowing costs cheaper.

A prolonged period of higher inflation would not go down well with US businesses or voters. It’s why financial markets have followed a recent trend known as TACO, helping stock markets remain at record levels.

The belief is that Trump always chickens out. He may have to back down if inflation takes off.

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Trump orders two nuclear submarines to be moved after ‘highly provocative’ comments from ex-Russian president

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Trump orders two nuclear submarines to be moved after 'highly provocative' comments from ex-Russian president

Donald Trump says he has ordered two nuclear submarines to be positioned in the “appropriate regions” in a row with former Russian president Dmitry Medvedev.

It comes after Mr Medvedev, who is now deputy chairman of Russia‘s Security Council, told the US president on Thursday to remember Moscow had Soviet-era nuclear strike capabilities of last resort.

On Friday, Mr Trump wrote on social media: “Based on the highly provocative statements of the Former President of Russia, Dmitry Medvedev, who is now the Deputy Chairman of the Security Council of the Russian Federation, I have ordered two Nuclear Submarines to be positioned in the appropriate regions, just in case these foolish and inflammatory statements are more than just that.

“Words are very important, and can often lead to unintended consequences, I hope this will not be one of those instances. Thank you for your attention to this matter!”

Dmitry Medvedev. Pic: Reuters
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Dmitry Medvedev. Pic: Reuters

The spat between Mr Trump and Mr Medvedev came after the US president warned Russia on Tuesday it had “10 days from today” to agree to a ceasefire in Ukraine or face tariffs, along with its oil buyers.

Moscow has shown no sign it will agree to Mr Trump’s demands.

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Who are the winners (if any) and losers of Trump’s tariffs?

Mr Medvedev accused Mr Trump of engaging in a “game of ultimatums” and reminded him Russia possessed a Soviet-era automated nuclear retaliatory system – or “dead hand” – after Mr Trump told him to “watch his words” and said he’s “entering very dangerous territory!”

Mr Medvedev, a close ally of Russian President Vladimir Putin, was referring to a secretive semi-automated Soviet command system designed to launch Russia’s missiles if its leadership was taken out in a decapitating strike.

He added: “If some words from the former president of Russia trigger such a nervous reaction from the high-and-mighty president of the United States, then Russia is doing everything right and will continue to proceed along its own path.”

He also said “each new ultimatum is a threat and a step towards war” between Russia and the US.

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