Live worm found in woman’s brain in world-first discovery
A woman who was experiencing forgetfulness and depression has had an 8cm-long parasitic roundworm removed from her brain.
The 64-year-old English woman, who was living in New South Wales, Australia, was admitted to hospital in January 2021 after three weeks of abdominal pain and diarrhoea, followed by a dry cough and night sweats.
By 2022, her symptoms had evolved to include forgetfulness and depression, prompting medical professionals to refer her to Canberra hospital.
An MRI scan of her brain revealed that a motile helminth – a parasitic roundworm – was living in the right frontal lobe lesion of her brain.
Surgical intervention became the only option, and doctors successfully removed the roundworm, which measured 8cm (80mm) in length and 1mm in diameter.
The live roundworm after it has been removed from the patient’s right frontal lobe. Pics: Centers for Disease Control and Prevention
Identified as a third-stage larva of the Ophidascaris robertsi nematode species, the case is unprecedented in medical history, and has been documented in the journal of Emerging Infectious Diseases.
Typically, this parasitic worm lives in the digestive tracts of carpet pythons indigenous to the Australian state of New South Wales.
Medical professionals suspect the woman inadvertently ingested the worm’s eggs by eating edible grasses that were tainted with snake faeces, however, the actual cause cannot be confirmed.
After the eggs hatched within her body, medics believe the larvae embarked on a journey to her brain. This could have been influenced by the medication she was taking, which compromised her immune system.
“We hypothesised that she inadvertently consumed eggs either directly from the vegetation or indirectly by contamination of her hands or kitchen equipment,” the medics said.
An image of the woman’s brain showing the right frontal lobe lesion
Ordeal began in 2021 – with evolving symptoms
The woman’s ordeal began in January 2021 when she was admitted to a hospital in Canberra.
Despite comprehensive tests, the results of her numerous medical tests remained inconclusive. Eventually, she received a diagnosis of pneumonia originating from an undisclosed source and was prescribed steroids.
Although her condition initially showed signs of improvement, she found herself readmitted to the hospital a few weeks later, plagued by a fever and an unrelenting cough.
Doctors suspected the presence of T-cell driven hypereosinophilic syndrome, a condition that can be life-threatening, characterised by the immune system going into overdrive. To address this, she was administered immunosuppressing medication as part of her treatment.
The worm seen under a microscope
A CT scan also unveiled multiple troubling findings, including pulmonary opacities, hepatic and splenic lesions.
Three weeks later, her condition worsened, prompting her admission to a tertiary hospital. With persistent fever and cough, her medical team escalated the investigation.
By January 2022, she experienced further changes, including forgetfulness and worsening depression over a three-month period, prompting doctors to examine her brain.
Subsequent scans unveiled a brain lesion, leading to her undergoing surgery in June of the previous year.
‘String-like structure’ discovered in brain
During the surgical procedure, an unusual “string-like structure” was discovered within the lesion, and to doctors’ astonishment, it began to wriggle.
Examination of the worm indicated its affiliation with a family of parasites typically exclusive to snakes. This marked the first documented instance of such a parasite infecting a human.
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Subsequent medical procedures revealed the absence of any additional worms residing within her body.
Half a year after the surgery, while the woman’s forgetfulness and depression had shown signs of improvement, they persisted to some extent.
Medical experts emphasised the significance of ongoing monitoring, as studies on rats have demonstrated that the worm’s eggs can endure within the body for over four years.
But they added that while the species of worm had been known to infect animals’ digestive systems, it had not been discovered in the brain of any species before.
The medics said that while the particular worm in question is exclusive to Australia, there are similar species located in other parts of the world, suggesting the potential for further occurrences in the future.
They also emphasised that the case underscored the persisting danger of zoonotic diseases transmitted between humans and animals.
Zoonotic diseases, which transfer from animals to humans, are frequently mentioned as potential triggers for pandemics.
Fresh appeals have been made for information on what would have been the 20th birthday of Ellis Cox, who was shot dead in Liverpool last June.
A number of people have been arrested in connection with the murder at Liver Industrial Estate, but no one has been charged yet.
The 19-year-old’s family and police have paid tribute to him and called for those with information to come forward.
He was shot in the back after a confrontation between his friends and another group of up to three males on Sunday 23 June.
Ellis Cox who was shot dead in June 2024. Pic: Merseyside Police
His mother Carolyn paid tribute in an appeal to coincide with what would have been his 20th birthday.
“He was so kind… so laid back, so calm, so mature for his age. And he was just funny. Very funny.
“He was my baby… no mum should have to bury a child. He was my life. And I don’t know what to do without him.”
Mum Carolyn Cox (left) and aunt Julie O’Toole (right) are looking for answers
Ellis’ mum described him as ‘kind” and “funny. Pic: Merseyside Police
Meanwhile, his aunt Julie O’Toole said he was “the sort of person I think you’d be hard pressed to find anyone to say anything negative about. He was loyal, fiercely loyal… everything was about his family”.
To pay tribute to Ellis, Liverpool City Council will be lighting up the Cunard Building and Liverpool Town Hall in orange on Saturday.
DCI Steve McGrath does not believe Ellis was involved in criminality
Detective Chief Inspector Steve McGrath, the senior investigating officer, spoke about the information gathered so far, six months on from Mr Cox’s murder.
“I’m satisfied that the group that he was with was probably the target… and I would say that’s got something in relation to do with localised drug dealing in that area. But Ellis had no involvement in that whatsoever,” he said.
He added that police are looking for “really significant pieces of evidence now”, including “trying to recover the firearm that was used in relation to this, looking to recover the bikes that were used by the offenders”.
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Mrs Cox also appealed for people to come forward with information.
“If you know anything, don’t let us get to [his] next birthday and still know nothing.
“We need to get justice for Ellis. And we need to get the people who took him from us off the streets.”
Former Manchester United and Scotland footballer Denis Law has died, at the age of 84.
In a statement, his family said: “It is with a heavy heart that we tell you our father Denis Law has sadly passed away. He fought a tough battle, but finally, he is now at peace.
“We would like to thank everyone who contributed to his wellbeing and care, past and much more recently.
“We know how much people supported and loved him and that love was always appreciated and made the difference.”
Denis Law in 2005. Pic: PA
The Aberdeen-born footballer previously announced in August 2021 that he had been diagnosed with dementia.
A prolific striker, Law scored 237 goals in 404 appearances for Manchester United, for whom he signed for a then-British record transfer fee in 1962.
He is the only man to have two statues dedicated to him at Old Trafford – one on the Stretford End concourse, the other as part of the United Trinity statue overlooking the stadium’s forecourt beside fellow great George Best and Sir Bobby Charlton.
Denis Law, third from left, as a statue featuring him alongside Sir Bobby Charlton and George Best – known as the ‘holy trinity’ – was unveiled in 2008. Pic: AP
The only Scottish player to have won the Ballon d’Or award, in 1964, he was also part of United’s triumphant campaign in the 1968 European Cup – in which they became the first English club to ever win the competition.
In a statement, the club said: “Everyone at Manchester United is mourning the loss of Denis Law, the King of the Stretford End, who has passed away, aged 84.
“He will always be celebrated as one of the club’s greatest and most beloved players.
Denis Law, centre, during Manchester United’s triumphant European Cup campaign in 1968. Pic: AP
“The ultimate goalscorer, his flair, spirit and love for the game made him the hero of a generation. Our deepest condolences go out to Denis’s family and many friends. His memory will live on forever more.”
Wayne Rooney, former United captain and the club’s all-time record goalscorer, described Law as a “legend”.
“Thoughts with all Denis’s family and friends,” he said in an online post.
Another former United captain, Gary Neville, said: “A great footballer and a great man. It’s a privilege and an honour to have spent time in your company. The King of the Stretford End.”
A tribute from the Scotland national team said Law was “a true great”.
“We will not see his likes again,” it said.
Law also played for Huddersfield Town, Manchester City, and Italian club Torino during his club career, and made 55 appearances for Scotland, scoring 30 goals for his country.
Manchester City said in a post on X: “The whole of Manchester, including everyone at City, is mourning with you. Rest in peace, Denis.”
The UK’s benchmark stock index has reached another record high.
The FTSE 100 index of most valuable companies on the London Stock Exchange closed at 8,505.69, breaking the record set last May.
It had already broken its intraday high at 8532.58 on Friday afternoon, meaning it reached a high not seen before during trading hours.
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The weakened pound has boosted many of the 100 companies forming the top-flight index.
Why is this happening?
Most are not based in the UK, so a less valuable pound means their sterling-priced shares are cheaper to buy for people using other currencies, typically US dollars.
This makes the shares better value, prompting more to be bought. This greater demand has brought up the prices and the FTSE 100.
The pound has been hovering below $1.22 for much of Friday. It’s steadily fallen from being worth $1.34 in late September.
Also spurring the new record are market expectations for more interest rate cuts in 2025, something which would make borrowing cheaper and likely kickstart spending.
What is the FTSE 100?
The index is made up of many mining and international oil and gas companies, as well as household name UK banks and supermarkets.
Familiar to a UK audience are lenders such as Barclays, Natwest, HSBC and Lloyds and supermarket chains Tesco, Marks & Spencer and Sainsbury’s.
Other well-known names include Rolls-Royce, Unilever, easyJet, BT Group and Next.
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FTSE stands for Financial Times Stock Exchange.
If a company’s share price drops significantly it can slip outside of the FTSE 100 and into the larger and more UK-based FTSE 250 index.
The inverse works for the FTSE 250 companies, the 101st to 250th most valuable firms on the London Stock Exchange. If their share price rises significantly they could move into the FTSE 100.
A good close for markets
It’s a good end of the week for markets, entirely reversing the rise in borrowing costs that plagued Chancellor Rachel Reeves for the past ten days.
Fears of long-lasting high borrowing costs drove speculation she would have to cut spending to meet self-imposed fiscal rules to balance the budget and bring down debt by 2030.
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They Treasury tries to calm market nerves late last week
Long-term government borrowing had reached a high not seen since 1998 while the benchmark 10-year cost of government borrowing, as measured by 10-year gilt yields, was at levels last seen around the 2008 financial crisis.
The gilt yield is effectively the interest rate investors demand to lend money to the UK government.
Only the pound has yet to recover the losses incurred during the market turbulence. Without that dropped price, however, the FTSE 100 record may not have happened.
Also acting to reduce sterling value is the chance of more interest rates. Currencies tend to weaken when interest rates are cut.
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