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Share on Pinterest The number of people dealing multiple chronic conditions is on the rise in the U.S.Hero Images Inc/Getty ImagesA study has found that adults in the U.S. are increasingly dealing with multiple chronic conditions.These cardiac, renal, and metabolic conditions include type 2 diabetes, heart disease, and kidney disease.These conditions are the leading cause of morbidity and mortality in the United States, and are estimated to account for every 1 in 3 deaths.

A new study found that the number of Americans with multiple cardiac, renal, and metabolic conditions is rising.

Approximately one in four adults have a cardiac, renal, or metabolic conditions condition and nearly 1 in 10 have multiple cardiac, renal, or metabolic conditions, according to the report, which published in JAMA Cardiology on September 27.

The risk of also increased with ageone in three adults 65 and older had a cardiac, renal, or metabolic condition, while almost 1 in 4 had overlapping conditions.

These conditions are the leading cause of morbidity and mortality in the United States and are estimated to account for every 1 in 3 deaths, according to study authors.

We have medications to treat the underlying mechanisms that contribute to co-existing cardiac, renal, and metabolic (CRM) conditions, however, they arent being prescribed or taken nearly as frequently as they should be.

The new report sheds light on how significantly the incidence of these conditions has grown over the past two decades along with the urgent need to address the situation.

The findings are doubly concerning as they demonstrate both an increase in the prevalence of cardiac, renal, and metabolic disease and concurrent high levels of undertreatment, Dr. Dmitriy Nevelev, Associate Director of Cardiology at Staten Island University Hospital, told Healthline. Nevelev wasnt involved in the study. Chronic conditions have become much more common since 1999

To determine the prevalence of CRM conditions in the U.S., the researchers evaluated health data from January 2015 through March 2020 sourced from the National Health and Nutrition Examination Survey (NHANES).

They compared those trends against NHANES health data collected between 1999 and 2002.

The analysis included 11,607 non-pregnant adults aged 20 and over.

Of the data pooled from 2015 to 2020, 26.3% had at least 1 CRM condition, 8% had at least two, and 1.5% had three CRM conditions.

The most common comorbid conditions were type 2 diabetes plus chronic kidney disease (3.2%), followed by cardiovascular disease plus type 2 diabetes (1.7%) and cardiovascular disease plus chronic kidney disease (1.6%).

The burden was greatest among non-hispanic Black individuals along with people who reported they were unemployed, of low socioeconomic status, or had no high school degree.

Disparities in access to healthcare services can result in delayed diagnosis and treatment of cardiac, renal, and metabolic conditions, leading to worse outcomes, said Dr. David Cutler, board certified family medicine physician at Providence Saint Johns Health Center in Santa Monica, CA. Cutler was not involved in the study.

Of those with three CRM conditions, roughly one-third (30.5%) did not report statin use, only 4.8% used medication common for weight loss and diabetes called glucagon-like peptide-1 receptor agonists (GLP1 agonists.) Additionally only 3% took medication commonly used to treat high blood sugar called sodium-glucose cotransporter 2 inhibitors (SGLT2).

Newer medications like GLP1 agonists for example, semaglutide and SGLT2 inhibitors which have been found to improve these conditions are very expensive and were found to be prescribed at a very low rate in this study, says Cutler.

The proportion of U.S. adults with multiple CRM conditions has grown significantly over the past few decades from 5.3% in 1999 to 8% in 2020.

The proportion of Americans with three CRM conditions also grew, from 0.7% in 1999 to 1.5% in 2020. How to combat the rising prevalence of multiple CRM conditions

Research shows that heart, kidney, and metabolic functions are intertwined and share the same risk factors, including obesity, hypertension, blood sugar that is too high or low, and cholesterol imbalance.

Diet and lack of physical activity can contribute to metabolic disorders and obesity, says Cutler.

Genetics, age, and access to healthcare play a role, too.

In addition, stress can affect health behaviors and contribute to the development of these conditions, he added.

The report says that issues with one body system may lead to dysfunction of others and the development of multiple morbidities.

Fortunately, we can use the common link between these conditions to personalize treatment and prevent their onset, says Nevelev.

There are drugs that target the underlying pathways involved in the development of comorbidities, such a SGLT2 inhibitors, and may help lower the prevalence of multiple conditions, however, they are being prescribed at a low rate.

Several factors are at play, including insurance coverage and the associated insurance authorizations burden, overall cost to the patient, prescriber comfort in using newer medications, fear of medication side effects, and in the case of GLP-1 antagonists availability, says Nevelev.

The rising prevalence of multiple conditions are expected to accelerate due to the COVID-19 pandemic.

We now have good data demonstrating pandemic-related decreases in physical activity and increases in sedentary activity and weight gain, he said.

The findings highlight the need to improve the situation and promote public health efforts, such as promoting healthy lifestyles, improving access to healthcare, and raising awareness about risk factors and early detection.

We have the tools to lower rates of these diseases. We have to make better use of them, says Cutler. The bottom line:

A new study found that the number of adults in the U.S. with multiple cardiac, renal, and metabolic (CRM) conditions is rising. There are medications to treat the underlying mechanisms that contribute to these co-existing conditions. However, they arent being prescribed or taken as frequently as they should be. The research sheds light on the urgent need to address the situation, ideally through awareness, screening, and improved access to healthcare.

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DeFi booming as $11B Bitcoin whale stirs ‘Uptober’ hopes: Finance Redefined

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DeFi booming as B Bitcoin whale stirs ‘Uptober’ hopes: Finance Redefined

DeFi booming as B Bitcoin whale stirs ‘Uptober’ hopes: Finance Redefined

An $11 billion Bitcoin whale returned to crypto markets this week, likely seeking trading opportunities tied to October’s historic crypto rallies and uncertainty in the US.

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Environment

Hiboy launches TITAN & TITAN Pro e-scooters with up to $699 savings, Anker SOLIX F3000 station at new $1,399 low, more

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Hiboy launches TITAN & TITAN Pro e-scooters with up to 9 savings, Anker SOLIX F3000 station at new ,399 low, more

We’re closing out this week’s Green Deals with some more major savings, headlined by Hiboy’s new TITAN Electric Scooter and TITAN Pro Electric Scooter, which are launching with up to $699 in savings starting from $1,001. Right behind them is Anker’s SOLIX F3000 Portable Power Station (and bundles) that is getting its $1,399 Prime Day low extended, as well as Mammotion’s YUKA Mini 500H and 700H robot lawn mowers starting from a $649 low. We also have EcoFlow’s latest 48-hour flash sale, a handy device from Goal Zero, and many other ongoing Prime Day sales waiting for you below – with all the continuing event’s savings collected into our Post-Prime Day Green Deals hub here.

Head below for other New Green Deals we’ve found today and, of course, Electrek’s best EV buying and leasing deals. Also, check out the new Electrek Tesla Shop for the best deals on Tesla accessories.

Hiboy launches new TITAN and TITAN Pro e-scooters with an up to 80-mile range, now starting from $1,001 (Up to $699 off)

As part of Hiboy’s ongoing Better Than Prime Day Sale, the brand has launched two new e-scooters that bring some serious power to commutes and joyrides, complete with bonus savings. You can now hop on Hiboy’s TITAN Electric Scooter at $1,001 shippedafter using the code HST9 at checkout for an additional 9% off, while Hiboy’s TITAN Pro Electric Scooter is down at $1,350 shippedafter using the code HSTP10 at check out for an additional 10% off. These two new models will carry full $1,700 and $2,000 price tags once the initial launch savings end, making this deal all the more enticing. While things last, you’re looking at $699 and $650 markdowns that save you some serious cash on some seriously powerful rides, while also setting the bar for future discounts down the road. You’ll find both these deals coming several hundred dollars under the TITAN and TITAN Pro Amazon pricing.

With these two new releases, Hiboy is showing folks just how fast and wild their e-scooters can get, with many often falling into the more budget-friendly realm. Things start with Hiboy’s TITAN electric scooter that arrives in futuristic industrial style, equipped with a 750W (1,000W peaking) motor and 48V 18Ah battery that provides up to 46 miles of travel at up to 25 MPH top speeds. Among its many features, you’ll find a dual suspension system, dual hydraulic brakes, 10-inch gel-filled tubeless tires, a wider-than-normal deck, zero-start capabilities and a half-twist throttle, a loud horn, dual headlights, a brake-activated taillight, ambient side lighting, a 3.5-inch LED color display, and more.

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On the other end of the series is the TITAN Pro e-scooter that brings more power and speed along for the ride. This supped-up model has been given dual 750W motors (each peaking at 1,000W) and a 48V 36Ah battery that not only ramps its possible top speeds up to 31 MPH, but also extends travel times up to 80 miles on a single charge. It brings along much of the same features as its base TITAN counterpart, with the main difference being the additional multi-function control buttons that allow you to switch between single and dual motor usage.

Hiboy’s Better Than Prime Sale will continue through October 12, giving you plenty of time to make decisions if you’re split between varying models – with prices starting from $320.

refrigerator open behind anker solix f3000 portable power station

Anker’s extended Prime Day savings offer latest SOLIX F3000 station and bundles at new lows starting from $1,399

As part of Anker’s extended SOLIX Prime Day Sale, which is continuing through the rest of the week, you can still score the brand’s latest F3000 Portable Power Station (and bundles) at their best prices starting from $1,399 shipped for the station with a FREE protective cover (valued at $99), beating out Amazon’s post-Prime pricing by $100. It carries a $2,599 MSRP since releasing back in June, which we saw drop down to this rate for the first time on Tuesday, when Prime Day officially began. It’s now continuing through the rest of the week, giving you more time to jump on the $1,200 price cut and score it at the best price we have tracked. Head below for the full lineup of ongoing bundle deals too.

If you want to learn more about this new power station, be sure to check out our original coverage of this deal here.

man and daughter plant tree while Mammotion YUKA mini robotic lawn mower mows grass around them

Mammotion’s YUKA Mini 500H and 700H robotic lawn mowers get $350 price cuts starting from a $649 low

By way of its official Amazon storefront, Mammotion is offering continued Prime Day savings on its YUKA Mini 500H Robotic Lawn Mower at $649 shipped, as well as its YUKA Mini 700H Robotic Lawn Mower at $849 shipped. These two models usually fetch $999 and $1,199 at full price, with this being the second-ever price cut to the YUKA Mini 500H’s all-time low with $350 cut from its tag, while the YUKA Mini 700H is getting the same sized price cut to its second-lowest rate – landing $100 above the one-time low that lasted only three days in September.

If you want to learn more about these two robots, be sure to check out our original coverage of these deals here.

ecoflow 800W alternator charger connected to power station in SUV with smart controls on phone

EcoFlow 48-hour flash sale drops 800W alternator charger to new $289 low, more from $104

As part of its extended Prime Day Sale, EcoFlow is offering a 48-hour flash sale on a power station, a generator, an alternator charger, and a DELTA Pro Ultra expansion battery bundle. The backup power solution amongst the bunch is the TRAIL 200 DC station, which you can score starting from $104 by checking out yesterday’s coverage. From there, it’s a matter of what kind of support or expansion you want to jump on, with the brand’s 800W Alternator Charger sitting at a lower-than-ever $289 shipped, for example, which also matches at Amazon right now. While it carries a $599 MSRP, we more often see it priced between $348 and $499, with some sales taking things lower. It was priced at $305 for the initial Prime Day savings, but is now falling even further to mark a new all-time low price and give you $210 off the going rate. Head below for the full lineup of flash deals.

If you want to learn more about this on-the-go charging solution, as well as the other offers, be sure to check out our original coverage of these 48-hour flash deals here.

man using goal zero torch light to see under hood of car

Goal Zero’s 500 Lumen Torch Light that doubles as a solar-charging 5,200mAh power bank hits $38

Amazon is offering the Goal Zero 500 Lumen Torch Light at $37.89 shipped. Usually fetching $50 outside of discounts, this device dropped to $40 back April, with discounts since returning the costs to this same rate over the rest of the year – including for both July and this month’s Prime Day events. The savings seem to be sticking around after the event ended last night, giving you extra time to pick it up with $12 shaved from the tag at the best price of the year.

If you want to learn more about this handy solar-charging gadget, be sure to check out our original coverage of this deal here.

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Best Fall EV deals!

Best new Green Deals landing this week

The savings this week are also continuing to a collection of other markdowns. To the same tune as the offers above, these all help you take a more energy-conscious approach to your routine. Winter means you can lock in even better off-season price cuts on electric tools for the lawn while saving on EVs and tons of other gear.

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Technology

Govini, a defense tech startup taking on Palantir, hits $100 million in annual recurring revenue

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Govini, a defense tech startup taking on Palantir, hits 0 million in annual recurring revenue

Govini, a defense tech software startup taking on the likes of Palantir, has blown past $100 million in annual recurring revenue, the company announced Friday.

“We’re growing faster than 100% in a three-year CAGR, and I expect that next year we’ll continue to do the same,” CEO Tara Murphy Dougherty told CNBC’s Morgan Brennan in an interview. With how “big this market is, we can keep growing for a long, long time, and that’s really exciting.”

CAGR stands for compound annual growth rate, a measurement of the rate of return.

The Arlington, Virginia-based company also announced a $150 million growth investment from Bain Capital. It plans to use the money to expand its team and product offering to satisfy growing security demands.

In recent years, venture capitalists have poured more money into defense tech startups like Govini to satisfy heightened national security concerns and modernize the military as global conflict ensues.

The group, which includes unicorns like Palmer Luckey’s Anduril, Shield AI and artificial intelligence beneficiary Palantir, is taking on legacy giants such as Boeing, Lockheed Martin and Northrop Grumman, that have long leaned on contracts from the Pentagon.

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Dougherty, who previously worked at Palantir, said she hopes the company can seize a “vertical slice” of the defense technology space.

The 14-year-old Govini has already secured a string of big wins in recent years, including an over $900-million U.S. government contract and deals with the Department of War.

Govini is known for its flagship AI software Ark, which it says can help modernize the military’s defense tech supply chain by better managing product lifecycles as military needs grow more sophisticated.

“If the United States can get this acquisition system right, it can actually be a decisive advantage for us,” Dougherty said.

Looking ahead, Dougherty told CNBC that she anticipates some setbacks from the government shutdown.

Navy customers could be particularly hard hit, and that could put the U.S. at a major disadvantage.

While the U.S. is maintaining its AI dominance, China is outpacing its shipbuilding capacity and that needs to be taken “very seriously,” she added.

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