Weight loss has always been big business, but it’s exploded of late due to surging demand for Ozempic, Wegovy and other new diabetes and obesity drugs.
In the first half of 2023, sales of Ozempic and Wegovy rose by 58% and 363%, respectively. That’s after quarterly prescriptions for those types of GLP-1 treatments, which mimic a hormone in the gut to suppress a person’s appetite, increased 300% between early 2020 and the end of last year.
But as consumers and businesses pour more money and resources into tackling the obesity epidemic, which costs the U.S. more than $170 billion a year, drug developers aren’t alone in coming up with innovative solutions.
Signos, a five-year-old startup, is taking an approach that doesn’t involve pills.
The company is using off-the-shelf continuous glucose monitors, or CGMs, and providing real-time diet and exercise recommendations based on an individual’s readings. CGMs are small sensors worn on the upper arm that track glucose levels, primarily for people with diabetes. The information is wirelessly sent to a smartphone, allowing the user to better prevent emergencies.
Signos uses CGMs built by Dexcom. The startup has its own app that shows users how their body responds to specific foods, what causes their glucose to spike and when they should exercise to get the best results for weight loss.
On Tuesday, Signos said it closed a $20 million funding round led by Cheyenne Ventures and GV, formerly known as Google Ventures. Dexcom Ventures also contributed to the financing. Signos said it will use the fresh capital to continue its research into metabolic health and to expand its team, which is currently around 45 people.
“Whether you have five pounds to lose or 100, we want to make sure we’re able to help everybody,” Sharam Fouladgar-Mercer, Signos’ co-founder and CEO, told CNBC in an interview.
Customers who sign up for Signos can choose a one-month, three-month or six-month plan. With the half-year plan, users pay $143 a month, which includes all of the pricey CGMs they’ll need during that time. The company declined to share specific details about how many people are currently using its platform.
Fouladgar-Mercer said the long timelines are designed to attract users who are serious about their weight-loss journey. Additionally, the sensors themselves have a long wear time. The Dexcom G6 and G7, the latest devices, can measure glucose for up to 10 days. Signos currently supports the G6 and will soon work with the G7 as well.
Fouladgar-Mercer said Signos is using Dexcom’s CGMs as part of a clinical study approved by an institutional review board designated by the U.S. Food and Drug Administration to monitor biomedical research involving real people.
Fouladgar-Mercer said he created the company in 2018 partly because of his own struggle to manage weight throughout his life. He trained as an athlete and played hockey in college, but he said he noticed how food often affected him differently from the way it affected his teammates.
He said he always felt that, in an effort to understand an individual’s metabolism, there was a “critical component” missing, and it had been nagging at him for 30 years.
Signos helps users understand the right decision to make in the moment, but they can go “behind the scenes” and learn as much about the science as they’d like, Fouladgar-Mercer said. Users can also integrate sleep data, heart rate data, and exercise data from their Apple Watch to personalize their profile even more.
“Once they trust the system works and they understand the methodology, they can just follow the really quick, here’s what I do, here’s what I do, here’s what I do,” Fouladgar-Mercer said. “And that’s how you get behavioral change.”
Though Dexcom primarily develops its CGMs for patients with diabetes, the company is also working toward broader applications. For instance, next year it’s releasing a new product meant for people who aren’t taking insulin. Similarly, Abbott Laboratories, which dominates the global CGM market, is hoping to bring its first consumer-facing CGM, called Lingo, to the U.S. next year, adding personalized coaching with recommendations about diet, sleep and exercise.
Fouladgar-Mercer said Signos has more data points than “anybody does in the world for non-diabetics.” He added that since the company built its first product almost five years ago, it’s been able to focus on fine-tuning its technology.
“I don’t want to incorrectly set expectations,” Fouladgar-Mercer said. “I think a lot of times, it’s like, ‘Oh, lost X pounds in X days.’ That’s not what we’re trying to accomplish. It’s really, how do we put you on a sustainable journey? And that journey is not going to be done in two or three days.”
Fouladgar-Mercer said Signos can work well alongside Ozempic and Wegovy from Novo Nordisk and other GLP-1 treatments. Novo Nordisk’s share price has quadrupled since 2018, and the company is now the most valuable in Europe.
Fouladgar-Mercer said GLP-1 drugs are a “powerful tool” that can help people jump-start weight loss, but it can be challenging to keep weight off if they stop taking the medication. Platforms such as Signos can help to reinforce and maintain a healthier lifestyle over time, he said.
Ultimately, he said, he wants people to use Signos to learn how to make better choices that work best for their bodies.
Signos, Fouladgar-Mercer said, can use technology and data “to drive behavioral change, and then wrap that all in a system that really is focused on driving and solving this biggest problem we have in America, which is weight.”
Andy Jassy, CEO of Amazon, speaks during an unveiling event in New York on Feb. 26, 2025.
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Amazon CEO Andy Jassy said Tuesday that he’s working to root out bureaucracy from within the company’s ranks as part of an effort to reset its culture.
Speaking at Amazon’s annual conference for third-party sellers in Seattle, Jassy said the changes are necessary for the company to be able to innovate faster.
“I would say bureaucracy is really anathema to startups and to entrepreneurial organizations,” Jassy said. “As you get larger, it’s really easy to accumulate bureaucracy, a lot of bureaucracy that you may not see.”
A year ago, as part of a mandate requiring corporate employees to work in the office five days a week, Jassy set a goal to flatten organizations across Amazon. He called for the company to increase worker-to-manager ratios by at least 15% by the end of the first quarter of this year.
Jassy also announced the creation of a “no bureaucracy email alias” so that employees can flag unnecessary processes or excessive rules within the company.
Amazon has received about 1,500 emails in the past year, and the company has changed about 455 processes based on that feedback, Jassy said.
The changes are linked to Jassy’s broad strategy to overhaul Amazon’s corporate culture and operate like the “world’s largest startup” as it looks to stay competitive.
Jassy, who took the helm from founder Jeff Bezos in 2021, has been on a campaign to slash costs across the company in recent years. Amazon has laid off more than 27,000 employees since 2022, and axed some of its more unprofitable initiatives. Jassy has also urged employees to do more with less at the same time that the company invests heavily in artificial intelligence.
Transforming Amazon into a startup-like environment isn’t an easy task. The company operates sprawling businesses across retail, cloud computing, advertising, and other areas. It’s the U.S. second-largest private employer, with more than 1.5 million employees globally.
“You have to keep remembering your roots and how useful it is to be scrappy,” Jassy said.
The StubHub logo is seen at its headquarters in San Francisco.
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Online ticket platform StubHub is pricing its IPO at $23.50, CNBC’s Leslie Picker confirmed on Tuesday.
The pricing comes at the midpoint of the expected range that the company gave last week. At $23.50, the pricing gives StubHub a valuation of $8.6 billion. StubHub will trade on the New York Stock Exchange under the symbol “STUB.”
The San Francisco-based company was co-founded by Eric Baker in 2000, and was acquired by eBay for $310 million seven years later. Baker reacquired StubHub in 2020 for roughly $4 billion through his new company Viagogo, which operates a ticket marketplace in Europe.
StubHub has been trying to go public for the past several years, but delayed its public debut twice. The most recent stall came in April after President Donald Trump‘s “Liberation Day” tariffs roiled markets.
The company filed an updated prospectus in August, effectively restarting the process to go public.
The IPO market has bounced back in recent months after an extended dry spell due to high inflation and rising interest rates. Klarna made its debut on the NYSE last week after the online lender also delayed its IPO in April. Tyler and Cameron Winklevoss’ Gemini, stablecoin issuer Circle, Peter Thiel-backed cryptocurrency exchangeBullish and design software company Figma have all soared in their respective debuts.
At the top of the pricing range StubHub offered last week, the company would have been valued at $9.2 billion. StubHub had sought a $16.5 billion valuation before it began the IPO process, CNBC previously reported.
StubHub said in its updated prospectus that first-quarter revenue increased 10% from a year earlier to $397.6 million. Operating income came in at $26.8 million for the period.
The company’s net loss widened to $35.9 million from $29.7 million a year ago.
In this photo illustration, the logo of TikTok is displayed on a smartphone screen on April 5, 2025 in Shanghai, China.
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President Donald Trump on Tuesday extended the deadline for ByteDance to divest TikTok’s U.S. business, which will be owned by an investor consortium that includes Oracle and Silver Lake, CNBC’s David Faber reported.
It’s the fourth time Trump has extended the deadline. The extension, as described in an executive order, precludes the Department of Justice from enforcing a national security law that would effectively ban TikTok in the U.S. until Dec. 16.
U.S. Treasury Secretary Scott Bessent revealed on Monday that a “framework deal” had been reached involving TikTok. Under the national security law, which would have come into effect on Wednesday, app store operators like Apple and Google and internet service providers would be penalized for providing services to TikTok’s U.S. operations if a deal was not reached.
Under the framework deal, about 80% of TikTok’s U.S. business would be owned by an investor consortium that includes Oracle, Silver Lake and Andreessen Horowitz, the Wall Street Journal on Tuesday reported. As part of the arrangement, existing U.S. users would need to shift to a new app, according to report.
Trump and Chinese President Xi Jinping are expected on Friday to discuss the terms of the TikTok-related deal that Treasury Secretary Scott Bessent revealed on Monday.
The deal, which is expected to close in the next 30 to 45 days, includes new investors, existing ByteDance investors and will result in Oracle maintaining its cloud computing agreement with TikTok, CNBC’s David Faber reported earlier on Tuesday.
Bessent said Tuesday during CNBC’s Squawk Box that Trump was willing to let TikTok “go dark,” which spurred China to agree to a deal. The Treasury Secretary said that the deal’s commercial terms had already been finalized “in essence” since March or April, but China put the deal on hold following Trump’s tough tariffs and trade policies.
“We were able to reach a series of agreements, mostly for things we will not be doing in the future that have no effect on our national security,” Bessent said Tuesday.
A senior White House official said in a statement that, “Any details of the TikTok framework are pure speculation unless they are announced by this administration.”