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A “repurposed” drug that could prevent breast cancer as well as treat it will be offered to almost 300,000 women, NHS officials have revealed.

Anastrozole has been used to treat hormone-sensitive breast cancer.

But trials have shown it can also stop the disease from occurring in the first place. It’s predicted cases could be cut by by 49% over 11 years.

The drug will be offered to 289,000 post-menopausal women who are considered to have at least a moderate risk of breast cancer in England.

“This is the first drug to be repurposed though a world-leading new programme to help us realise the full potential of existing medicines in new uses to save and improve more lives,” NHS chief executive Amanda Pritchard said.

Anastrozole was first recommended as a preventive option by the National Institute for Health and Care Excellence (Nice) in 2017, but, with the drug unlicensed in this use, uptake remained low.

Now scientists have found the protective effect lasts for years after a woman has stopped taking the drug – and has been licensed by the Medicines and Healthcare products Regulatory Agency .

Lesley-Ann Woodhams, who has a family history of the condition, completed the full five-year course of anastrozole in January 2023 and described it as a “gift”.

Lesley-Ann Woodhams has a history of breast cancer in her family
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Lesley-Ann Woodhams has a history of breast cancer in her family

“I’d watched my mum battle breast cancer and my risk was very high,” she said.

“I could live a life without constantly worrying or giving a thought to what could be if I’d developed breast cancer.

“It really was a gift, it gave my family and myself peace of mind and more importantly, a continued future to look forward to.”

breast cancer symptoms

You should see a GP if you notice any of the following:

• a new lump or area of thickened tissue in either breast that was not there before;

• a change in the size or shape of one or both breasts;

• a discharge of fluid from either nipple;

• a lump or swelling in either armpit;

• a change in the look or feel of skin, such as puckering or dimpling, a rash or redness;

• a rash (like eczema), crusting, scaly or itchy skin or redness on or around the nipple;

• a change in the appearance of a nipple, such as becoming sunken into the breast.

How does it work?

The treatment is taken as a 1mg tablet, once a day for five years and works by cutting down the amount of oestrogen the body makes by blocking an enzyme called aromatase.

The most common side effects of the medicine are hot flushes, feeling weak, pain or stiffness in the joints, arthritis, skin rash, nausea, headache, osteoporosis, and depression.

Breast cancer is the most common cancer in England, with around 47,000 women in England diagnosed each year.

Baroness Delyth Morgan, chief executive at the charity Breast Cancer Now, said the move is a “major step forward” that will enable more women to reduce their chance of developing the disease.

Read more from Sky News:
Most people can’t identify lesser-known symptoms of breast cancer
Surgeons carry out caesarean and ovaries removal at same time to cut cancer risk
Cervical cancer treatment breakthrough could cut deaths by 35%

Health Minister Will Quince said: “We’ve already seen the positive effect anastrozole can have in treating the disease when it has been detected in post-menopausal women and now we can use it to stop it developing at all in some women.”

The moves adds to the NHS’s armoury of preventative breast cancer medication, with tamoxifen and raloxifene already licensed to prevent breast cancer.

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Poem shows how to check for breast lumps

According to the NHS, the first symptom of breast cancer most women notice is a lump or an area of thickened tissue in their breast.

Most breast lumps are not cancerous, but it’s always best to have them checked by a doctor, officials say.

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Lionesses praised after winning Women’s Euros – with bus parade confirmed this week

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Lionesses praised after winning Women's Euros - with bus parade confirmed this week

England fans across the country have heaped praise on the team after winning Euro 2025, with a bus parade celebration set for Tuesday.

Sarina Wiegman’s Lionesses took home their second Euros trophy in consecutive tournaments after beating Spain 3-1 on penalties in the final.

Chloe Kelly scored the winning spot-kick following two huge saves from goalkeeper Hannah Hampton, after Alessia Russo scored an equaliser to send the game to a shootout.

As it happened: England beat Spain on penalties to retain title

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England fans celebrate across the UK

After England win, it was announced that an open-top bus parade will be held in London on Tuesday along The Mall, which will start at 12.10pm.

The celebrations will culminate in a stage ceremony at the Queen Victoria Memorial in front of Buckingham Palace at approximately 12.30pm

Fans can attend for free, and Sky News will broadcast it live.

‘You’ve made the nation proud’ – Starmer

Prime Minister Sir Keir Starmer was among the millions congratulating the Lionesses, posting on social media to praise the champions

“What a team. What a game. What drama,” he said.

“You dug deep when it mattered most and you’ve made the nation proud. History makers.”

The roof almost came off the Manchester clubhouse where Ella Toone started her journey


Greg Milam

Greg Milam

Chief North of England correspondent

@GregMilamSky

Nowhere was the roar for the Lionesses louder than in the Astley and Tyldesley Miners Welfare club on the outskirts of Manchester.

The club where a five-year-old Ella Toone started her journey to England stardom, like so many places across the country, hosted nail-biting, table-thumping and, ultimately, deafening watch parties.

The roof almost came off the clubhouse when Chloe Kelly’s winning penalty went in.

Red bucket hats emblazoned with Toone’s now-famous ‘Buzzing My Head Off’ catchphrase were thrown in the air.

“Absolutely ecstatic,” said Lorraine Warwick-Ellis, who runs the pathway development for women and girls at the club.

“I was very nervous, very worried about penalties but we did it in the end.”

The success of the Lionesses has driven a huge boom in the popularity of women’s and girls football in recent years. She hopes this win will have a similar effect.

“I hope it cements the girls who are already here, keeps them engaged, and I hope it brings more girls down who want to be footballers and see that it’s open for everybody.”

It had been a pretty sombre watch for much of the game after Spain took the lead – but it erupted into life after Alessia Russo’s equaliser.

The shootout was the usual emotional rollercoaster but young fans seem to have greater faith in the Lionesses.

Among the jubilant teenagers celebrating in the clubhouse were two who have followed Toone’s path to academies at professional clubs.

“It’s unbelievable, they’re amazing, Chloe Kelly, I just don’t know what to say about her,” said Natasha Greenhouse. “We knew if it went to penalties that they’d do it.”

Tamsin Gallagher said: “They’ve done it the hard way all the way through the Euros but we all believed in them. Come on England.”

The party in Manchester and around the country and only just begun.

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‘I am so incredibly proud’

Prince William and Princess Charlotte, who were in attendance at St Jakob-Park in Basel, added on social media: “What a game!

“Lionesses, you are the champions of Europe and we couldn’t be prouder of the whole team. Enjoy this moment England.”

King hails Lionesses… and calls for World Cup

In a post on the official Royal Family account on X, King Charles also sent his “most heartfelt congratulations on winning the Euros 2025” to the Lionesses.

“For more years than I care to remember, England fans have sung that famous chant ‘football’s coming home’,” he said.

“As you return home with the trophy you won at Wembley three years ago, it is a source of great pride that, through sporting skill and awesome teamwork, the Lionesses have made those words ring true.

“For this, you have my whole family’s warmest appreciation and admiration. More than that, though, you have shown through your example over past weeks that there are no setbacks so tough that defeat cannot be transformed into victory, even as the final whistle looms.”

The monarch ended his statement by saying “the next task is to bring home the World Cup in 2027 if you possibly can!”

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Culture Secretary Lisa Nandy added: “What an absolutely extraordinary achievement by our Lionesses – once again they have made history and united the country with pride and joy.”

Reform UK’s Nigel Farage said “well done” to the team and “what an absolutely fantastic watch,” while Conservative leader Kemi Badenoch said: “What an achievement. What a team!”

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Man suffers cardiac arrest onboard boat trying to reach UK

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Man suffers cardiac arrest onboard boat trying to reach UK

A man has died after suffering cardiac arrest onboard a boat attempting to reach the UK.

The vessel turned back towards Equihen beach on the French coast yesterday morning.

A nurse tried to resuscitate the man but was unsuccessful.

Pic: PA
Image:
Pic: PA

French authorities have now launched an investigation into the circumstances.

A spokesperson for Doctors Without Borders, also known as MSF, has criticised authorities on both sides of the Channel.

Jacob Burns said: “Yet again we have a tragedy in the Channel, that is the consequence of the deadly, costly and ineffective security policies implemented by the UK and France.”

Pic: PA
Image:
Pic: PA

Later on Saturday, a lifeboat carried migrants who have made the voyage into the Port of Dover.

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Photographs showed them huddled under blankets and orange life jackets on board.

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Protesters clash over asylum hotels

Provisional statistics from the Home Office suggest almost 24,000 people have arrived on small boats in the UK so far this year.

Towns and cities across the UK have seen protests in recent days, primarily outside hotels believed to be housing asylum seekers.

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Women’s Euros final: The Lionesses face Spain tonight – and they’re seeking revenge

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Women's Euros final: The Lionesses face Spain tonight - and they're seeking revenge

Here the Lionesses are again. Another final. Another showdown with Spain.

All of a sudden, what was once so anticipated and longed for can start to seem expected rather than extraordinary.

What happened to the great underachievers of world football? They are now consistently among the final two going for glory.

England wins
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At Euro 2022, the Lionesses ended England’s 56-year wait for a major trophy by beating Germany 2-1 after extra time. Pic: Reuters

No one is taking that for granted.

Especially not Leah Williamson, with the chance to retain the European Championship trophy lifted three years ago at Wembley.

“The opportunity of tomorrow and what’s on offer is the best thing in football,” the England captain said. “I think we don’t necessarily carry the weight of it and how much it means to people, but we’re aware of it because it means the same to us.”

So often they were only watching other nations making finals.

More on Lionesses

England’s first was the men winning the 1966 World Cup.

England v Spain: All you need to know

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Lionesses ‘know what win would mean to nation’

Then, with the rebirth of women’s football after bans and neglect, it was the Lionesses’ turn to make it to the finals – in 1984 and 2009.

And the Three Lions had to wait until 2021 to make it to a final, losing to Italy on penalties at Wembley.

It kickstarted an incredible run of five successive years of finals for England senior teams – with another men’s Euros final defeat in 2024.

The Lionesses have led the way, bringing football home by defeating Germany in the Euro 2022 final at Wembley.

They just missed out on going one better when reaching a first Women’s World Cup final a year later.

Soccer Football - FIFA Women's World Cup Australia and New Zealand 2023 - Final - Spain v England - Stadium Australia, Sydney, Australia - August 20, 2023 England manager Sarina Wiegman reacts REUTERS/Carl Recine
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England manager Sarina Wiegman reacts to defeat against Spain at the Women’s World Cup final in 2023. Pic: Reuters

Soccer Football - FIFA Women's World Cup Australia and New Zealand 2023 - Final - Spain v England - Stadium Australia, Sydney, Australia - August 20, 2023 England's Lauren James looks dejected after losing the world cup final REUTERS/Amanda Perobelli
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Lauren James looks dejected after their World Cup defeat, but is confirmed fit for Sunday’s revenge match against Spain. Pic: Reuters

Now, in Basel, comes the chance for revenge against Spain – even though no one in the England camp is saying that, publicly at least, in Switzerland.

Especially knowing how challenging a task it is coming up again against Aitana Bonmati and Alexia Putella – the recent winners of football’s biggest individual honours.

England fans celebrate after England beat Italy at Women's Euro 2025. Pic: Reuters
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England fans celebrating after England beat Italy to reach the finals. Pic: Reuters

Soccer Football - FIFA Women’s World Cup Australia and New Zealand 2023 - Final - Fans in Manchester watch Spain v England - Piccadilly Gardens, Manchester, Britain - August 20, 2023 England fans watch the match Action Images via Reuters/Jason Cairnduff
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Given England’s history against Spain, it could be a nerve-wracking time for England fans. File pic: Action Images/Reuters

But this is Spain’s first Euros final.

And there is some fear from the world champions at England’s grit and resolve to produce comebacks late in the quarter-finals and semi-finals – with 19-year-old Michelle Agyemang’s goals integral to the fightbacks.

England celebrate after defeating Italy in the Women's Euro 2025 semi-final. Pic: Reuters
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England celebrate their semi-final win against Italy to reach the finals. Pic: Reuters

Michelle Agyemang celebrates scoring her side's opening goal.
Pic: AP
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Michelle Agyemang has propelled England to the Euro 2025 final with two vital goals. Pic: AP

Spain captain Irene Paredes reflected yesterday on how the Lionesses can flip a result late on.

But she was also discussing how their World Cup win was tarnished by the on-pitch kiss that led to former Spanish federation president Luis Rubiales being convicted of a sexual assault on striker Jenni Hermoso.

It sparked a wider clamour in Spain for improved rights and respect for women.

Read more from Sky News:
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Sarina Wiegman on the Euros final
Listen: Why Lucy Bronze is ‘golden girl’

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Spain’s players struggle for respect

“Since then [2023] we took big steps forward,” Paredes said.

“I think this idea is disappearing from society. I still believe we have to continue opening doors… we’re a reference for boys and girls in society, but we still have things to do.”

It is a reminder that while tonight is about collecting silverware, both England and Spain know that emerging as champions can drive further growth in women’s football back home.

Amid it all, they’ll try to savour just what reaching a final means and how rare they are – until recently for English and Spanish women.

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