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A “repurposed” drug that could prevent breast cancer as well as treat it will be offered to almost 300,000 women, NHS officials have revealed.

Anastrozole has been used to treat hormone-sensitive breast cancer.

But trials have shown it can also stop the disease from occurring in the first place. It’s predicted cases could be cut by by 49% over 11 years.

The drug will be offered to 289,000 post-menopausal women who are considered to have at least a moderate risk of breast cancer in England.

“This is the first drug to be repurposed though a world-leading new programme to help us realise the full potential of existing medicines in new uses to save and improve more lives,” NHS chief executive Amanda Pritchard said.

Anastrozole was first recommended as a preventive option by the National Institute for Health and Care Excellence (Nice) in 2017, but, with the drug unlicensed in this use, uptake remained low.

Now scientists have found the protective effect lasts for years after a woman has stopped taking the drug – and has been licensed by the Medicines and Healthcare products Regulatory Agency .

Lesley-Ann Woodhams, who has a family history of the condition, completed the full five-year course of anastrozole in January 2023 and described it as a “gift”.

Lesley-Ann Woodhams has a history of breast cancer in her family
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Lesley-Ann Woodhams has a history of breast cancer in her family

“I’d watched my mum battle breast cancer and my risk was very high,” she said.

“I could live a life without constantly worrying or giving a thought to what could be if I’d developed breast cancer.

“It really was a gift, it gave my family and myself peace of mind and more importantly, a continued future to look forward to.”

breast cancer symptoms

You should see a GP if you notice any of the following:

• a new lump or area of thickened tissue in either breast that was not there before;

• a change in the size or shape of one or both breasts;

• a discharge of fluid from either nipple;

• a lump or swelling in either armpit;

• a change in the look or feel of skin, such as puckering or dimpling, a rash or redness;

• a rash (like eczema), crusting, scaly or itchy skin or redness on or around the nipple;

• a change in the appearance of a nipple, such as becoming sunken into the breast.

How does it work?

The treatment is taken as a 1mg tablet, once a day for five years and works by cutting down the amount of oestrogen the body makes by blocking an enzyme called aromatase.

The most common side effects of the medicine are hot flushes, feeling weak, pain or stiffness in the joints, arthritis, skin rash, nausea, headache, osteoporosis, and depression.

Breast cancer is the most common cancer in England, with around 47,000 women in England diagnosed each year.

Baroness Delyth Morgan, chief executive at the charity Breast Cancer Now, said the move is a “major step forward” that will enable more women to reduce their chance of developing the disease.

Read more from Sky News:
Most people can’t identify lesser-known symptoms of breast cancer
Surgeons carry out caesarean and ovaries removal at same time to cut cancer risk
Cervical cancer treatment breakthrough could cut deaths by 35%

Health Minister Will Quince said: “We’ve already seen the positive effect anastrozole can have in treating the disease when it has been detected in post-menopausal women and now we can use it to stop it developing at all in some women.”

The moves adds to the NHS’s armoury of preventative breast cancer medication, with tamoxifen and raloxifene already licensed to prevent breast cancer.

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Poem shows how to check for breast lumps

According to the NHS, the first symptom of breast cancer most women notice is a lump or an area of thickened tissue in their breast.

Most breast lumps are not cancerous, but it’s always best to have them checked by a doctor, officials say.

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PM dismisses calls for investigation into Reeves over rental ‘mistake’

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PM dismisses calls for investigation into Reeves over rental 'mistake'

Sir Keir Starmer has dismissed calls for an investigation into his chancellor after she apologised for putting her family home up for rent without obtaining the necessary licence.

Rachel Reeves wrote to the prime minister to “sincerely” apologise for the “inadvertent error”, which was first reported by the Daily Mail.

The newspaper reported that the chancellor rented her family home in Dulwich when she moved into Number 11 Downing Street, but was unaware she had to obtain a licence to do so.

Some London boroughs require private landlords to obtain a specific kind of licence if they are putting their property up for rent – including Southwark Council, where Ms Reeves’ home is listed.

The newspaper said Ms Reeves had now applied for a licence, but the Conservatives have called for an investigation.

A spokesperson for Ms Reeves said: “Since becoming chancellor, Rachel Reeves has rented out her family home through a lettings agency.

“She had not been made aware of the licensing requirement, but as soon as it was brought to her attention, she took immediate action and has applied for the licence.

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“This was an inadvertent mistake and in the spirit of transparency, she has made the prime minister, the independent adviser on ministerial standards and the parliamentary commissioner for standards aware.”

It is understood that Sir Laurie Magnus, the prime minister’s ethics adviser, has not launched an investigation into Ms Reeves.

Sir Keir said further investigation into the issue was “not necessary” after consulting Sir Laurie.

In a letter to Ms Reeves, he suggested her apology was a “sufficient resolution”.

Daisy Cooper, deputy leader of the Liberal Democrats, said the chancellor was adding to the government’s “list of scandals”.

“The chancellor is meant to be delivering growth but the only thing she appears to be growing is the government’s list of scandals,” she said.

“Just weeks before the budget, this risks seriously undermining confidence in this government and its ability to focus on the urgent tasks at hand.”

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Chancellor faces tough budget choices

The development comes weeks before Ms Reeves delivers her budget on 26 November.

She is rumoured to be considering a series of tax hikes, including a new tax on the sale of homes worth more than £500,000 to replace stamp duty.

Read more:
What tax rises and spending cuts could Reeves announce?
Why is there a budget black hole?

Under the proposal, sellers, instead of buyers, would be responsible for paying the tax.

The chancellor is understood to be looking at an annual 1% charge on the amount a property’s value exceeds £2m – a £10,000-a-year levy for homes worth £3m.

Another proposal would see capital gains tax (CGT) charged when someone sells their main home, based on the amount it has increased in value during ownership.

Reports suggest this would only be applied to the most expensive properties, with a possible threshold of £1.5m, which would affect about 120,000 homeowners and higher-rate taxpayers getting CGT bills of nearly £200,000.

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Wrongly-released migrant sex offender Hadush Kebatu claims he was ‘ignored’ by police while trying to hand himself in

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Wrongly-released migrant sex offender Hadush Kebatu claims he was 'ignored' by police while trying to hand himself in

Migrant sex offender Hadush Kebatu, who was wrongly freed from prison, has claimed in an interview with Sky News that he tried to hand himself in to police a day before he was arrested, but was ignored by officers.

The Home Office said Kebatu, 38, was deported from the UK on Tuesday night.

Speaking to Sky News after he arrived back in Ethiopia on Wednesday morning, Kebatu shared details of his accidental release from HMP Chelmsford on 24 October and the two-day manhunt that followed.

The convicted sex offender was repeatedly questioned on his crimes, but Sky News has chosen not to broadcast this part of the interview.

‘Ignored’ by police

The morning after he was released from prison, Kebatu claimed he tried to hand himself into police, but was ignored.

He said: “I [told] police, look here, police I am wanted man, I am arrested, I will give you my hand, please help where is police station? He ignored me, he drove [off].”

He added that he told the officer his name and that he was mistakenly released from prison.

“I am not unknown. The police station, where is the place? But also I go to police, I will give you my hand please help me where is the police station, take me, I am wanted.

“You know me, or my image, my name is Hadush Kabatu, nationality Ethiopia. Please, I was the mistake release from Chelmsford prison. Please help me.”

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Moment Hadush Kebatu put on deportation flight

Responding to Kebatu’s claims, the Metropolitan Police told Sky News: “The Met is not aware of any evidence to support the claims that Kebatu approached officers on Saturday morning.

“The actions of officers who responded to the sighting of him on Sunday morning show how seriously they were taking the manhunt. Kebatu’s actions on the morning of his arrest were more like those of someone trying to avoid officers, not trying to hand himself in.”

Release from prison

Kebatu was released by HMP Chelmsford a month into his 12-month sentence on the expectation he would be picked up by immigration enforcement.

He said after he was released he waited more than three hours outside the prison, for what he described as someone who was “responsible” for him.

He said: “At that time I am waiting more than three hours… who [is] responsible for me? Where is Home Office, where is [immigration]?

“I was told there was a bus. Also, all the experts, they all ignored me.”

In another Sky News story, a delivery driver who spoke to Kebatu outside Chelmsford prison said he looked “confused”.

The driver said he was approached by the prisoner, who had no idea where he was supposed to go. He said Kebatu waited outside the prison for roughly “an hour and a half” before leaving.

Kebatu said after he left the prison, he asked a passerby where the train station was. He claimed someone helped him, and bought him a train ticket for £18.

Kebatu then travelled to London. He was spotted later that evening in Stratford, east London, and then the Dalston area of Hackney.

Kebatu's movements the day he was released from prison
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Kebatu’s movements the day he was released from prison

The Ethiopian national arrived in the UK on a small boat on 29 June. Days after his arrival, he sexually assaulted a 14-year-old girl and a woman in Epping, Essex, where he was staying.

He was found guilty of two counts of sexual assault, one count of attempted sexual assault, one count of inciting a girl to engage in sexual activity and one count of harassment without violence.

He was jailed on 23 September.

When approached by Sky News, the Ministry of Justice (MoJ) pointed to a statement made by Justice Secretary David Lammy upon Kebatu’s deportation: “Kebatu has been returned to Ethiopia where he belongs.

“I am grateful to Home Office colleagues for acting swiftly to secure his deportation. I have been clear from the outset that a mistake of this nature is unacceptable, and we must get to the bottom of what happened.

“I have established an independent investigation chaired by Dame Lynne Owens into last Friday’s events to get the public the answers they rightly deserve, and we have introduced the strictest checks ever seen in our prison system to stop similar unacceptable errors in future.”

Essex Police, who arrested Kebatu after the assaults in July, told Sky News: “Our officers responded quickly to the reports of the sexual assaults committed in Epping and arrested Hadush Kebatu on the same day the offences were reported to us.

“Kebatu was then immediately remanded in custody, while officers acted diligently and professionally securing charges and building a case which saw Kebatu convicted following a trial. Protecting women and girls is a priority for Essex Police and our swift and thorough actions highlight our commitment to this.”

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Deported migrant sex offender given £500 to leave country

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Deported migrant sex offender given £500 to leave country

Migrant sex offender Hadush Kebatu was given £500 to be deported to Ethiopia following his mistaken release from prison, Sky News understands.

The government, who confirmed he was escorted on to a plane at Heathrow Airport on Tuesday night, said he has no right to return to the UK.

But Sky News understands Kebatu was handed a discretionary payment of £500 as part of efforts to avoid a lengthy legal challenge after he made threats to disrupt his removal.

Home Secretary Shabana Mahmood said she “pulled every lever” to deport Kebatu, although it is thought the decision about the payment was made by removal teams, not ministers.

“I am pleased to confirm this vile child sex offender has been deported. Our streets are safer because of it,” she said.

Hadush Kebatu seen on the plane during his deportation flight
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Hadush Kebatu seen on the plane during his deportation flight

Kebatu was found and arrested by the Metropolitan Police in the Finsbury Park area of north London at around 8.30am on Sunday following a manhunt.

Last month, he was found guilty of sexually assaulting a schoolgirl and a woman in Epping, Essex, just over a week after arriving in the UK on a small boat.

Hadush Kebatu was arrested on Sunday after his mistaken release
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Hadush Kebatu was arrested on Sunday after his mistaken release

He was expected to be deported, but instead of being handed over to immigration officials, he was released in error from HMP Chelmsford on Friday.

He spent just under 48 hours at large before he was apprehended.

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Prisoner releases: ‘A problem on the rise’

The accidental release sparked widespread alarm and questions over how a man whose crimes sparked protests in Epping over the use of asylum hotels was able to be freed.

Ms Mahmood said: “Last week’s blunder should never have happened – and I share the public’s anger that it did.”

Anti-asylum demonstrators in Epping, Essex. Pic: PA
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Anti-asylum demonstrators in Epping, Essex. Pic: PA

Read more from Sky News:
Military barracks to be used to house asylum seekers
Lammy blames ‘human error’ for release of migrant sex offender

On Sunday, Justice Secretary David Lammy said an exclusive Sky News interview will be used as part of an independent inquiry into the mistaken release.

Speaking to Sky’s national correspondent Tom Parmenter, a delivery driver who spoke to Kebatu at HMP Chelmsford described him as being “confused” as he was being guided to the railway station by prison staff.

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Local council reads family statement: ‘My family feels massively let down’

The migrant is said to have returned to the prison reception four or five times before leaving the area on a train heading to London.

Mr Lammy, who put Kebatu’s release down to human error, said he has ordered an “urgent review” into the checks that take place when an offender is released from prison, and new safeguards have been added that amount to the “strongest release checks that have ever been in place”.

From Monday, new checks include five pages of instructions and demands that more senior prison staff sign off on a release, according to documents obtained by Sky News.

“I have been clear from the outset that a mistake of this nature is unacceptable, and we must get to the bottom of what happened,” said Mr Lammy.

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