Nitazenes: The new synthetic opioids stronger than heroin that are being cut into drugs
Charlotte, not her real name, wanders back and forth with her empty coffee cup held out towards the tide of commuters coming through the barriers.
Rush hour at Whitechapel underground station is the best time of day for the small, frail, 23-year-old to earn enough change to pay for her next hit.
She’s agitated, but for the briefest moment agrees to talk. I ask if any symptoms from her drug use have changed recently. “I’ve got holes in my legs,” she says. “There’s no skin, just holes. It’s painful.”
Synthetic opioids seized by officers. Pic: Met Police
Her legs are bandaged. She says the strange bores in her flesh have only appeared in the last few months and is unsure why.
But drug charity workers are convinced this is a symptom of a terrifying evolution in the drug market – a growing prevalence of dangerous synthetic opioids being cut into drugs like heroin.
The deadliest, nitazenes, are the newest killer on the streets.
“I’m seeing people coughing up blood. I’m seeing people dying,” says crack cocaine user Rory, who we meet in Aldgate in East London.
“Any drug you are buying off the street you’re taking a risk. These people are in it for the money and the purer it is, the less they make – so they are putting other stuff in it.”
Crack cocaine user Rory
The opioid fentanyl is 50 times stronger than heroin and is the primary drug in North America, where synthetic opioids are estimated to have caused 75,000 deaths in the US last year.
Nitazenes have similar properties to fentanyl, but can be up to 300 times stronger than heroin. Only this week, several have been classified as Class A drugs.
First detected in the UK from a sample of white powder found in the back of a taxi in Wakefield in April 2021, nitazenes have since been found in heroin, cannabis, cocaine, in a vape and most prevalently in black market pills sold as the anti-anxiety drug diazepam.
‘Substantial risk of overdose, hospitalisation, and death’
In October, a police raid on a “sophisticated factory” in Waltham Forest recovered approximately 150,000 nitazene tablets, the largest-ever recovered stash of synthetic opioids. Eleven people were arrested.
Detective Superintendent Helen Rance, who is leading the investigation, said: “Synthetic opioids have been detected in batches of heroin found in London and across the UK; they substantially raise the risk of incredibly serious harm to the user and are believed to be linked to a number of deaths.”
Recently, the opioid is thought to have been cut into a batch of drugs in Dublin, causing 57 people to overdose within a few days.
Professor Eamon Keenan, from the Health Safety Executive, said: “These pose a substantial risk of overdose, hospitalisation, and death.”
Meg Jones, director of social justice charity Cranstoun, said: “We are seeing nitazenes pop up in pockets all over the UK and it is incredibly concerning.”
She added: “There are an increasing number of synthetic opioids being detected in drugs that people thought were very different. We need to see government action quickly on this, because we are sleepwalking into what I would deem to be a public health crisis, and we are not prepared for it in the UK at all.”
Action means more testing and provision of drugs that can counter the effects of opioid overdose.
Read more:
The killer painkiller
Opioid that’s 500 times stronger than morphine faces tougher controls after 25 deaths
Taliban crackdown means drugs produced in UK are more deadly
Outreach worker Abdirahim Hassan, founder of East London community group Coffee Afrik, agrees. He showed me a video of a young woman who appears to have overdosed. She is slumped unconscious on the pavement in Whitechapel.
Outreach worker Abdirahim Hassan
Her body is in the prayer position, her torso flat over her knees, her face pressed against the ground. “She’s just frozen. Her eyes are closed, and people are just walking past,” said Abdirahim. “She’s a young woman, maybe 24, somebody’s daughter.”
Abdirahim said a crackdown on heroin production by the Taliban has successfully stemmed the flow of heroin from Afghanistan which had previously provided 95% of the UK heroin market. That’s led to a boom in the easier to produce, more deadly synthetics.
“What it means is there’s a much higher risk of overdose and death,” he said. “But it’s a cheaper product and more potent so people are in greater crisis and there is not enough testing.”
Birmingham also saw a spike in the detection of nitazenes. Sky News was given access to a unique project in West Midlands police cells, run by the charity Cranstoun.
Steve Whitby is a drug and alcohol worker who visits suspects in their cells. The idea is that drug rehabilitation services reach out to offer support to addicts while they are in police custody.
Drug and alcohol worker Steve Whitby is interviewed by Farrell
On one cell visit, Steve warns an addict, who is also a suspected shoplifter, about the dangers of nitazenes. He told him: “So these are synthetic drugs that dealers are putting into heroin – but it’s causing lots of people to die from overdose.”
He told the man he shouldn’t take drugs alone and that he will leave a kit with his belongings which includes two syringes of naloxone, an antidote of opioid overdose. He explained the man will have to teach whoever is with him how to use it.
Naxolone is a treatment for people who have overdosed
This pilot in Birmingham is believed to be the first time naloxone has been given to addicts in custody, and the charity said this needs to become a national provision.
The Cranstoun programme in police custody suites is funded by the West Midlands police and crime commissioner.
“In essence, this saves more lives than any other intervention,” said Steve as he demonstrated how to inject the clear liquid into the side of the thigh.
He said sometimes it’s dispensed to the children of addicts so they can save their parents lives if they overdose.
As such a newcomer to the UK market and often concealed as something else, there is little data about the prevalence of nitazenes.
Pic: Met Police
The opioid is even more dangerous for those who have never taken it before
However, Wedinos, a service based in Wales where people can send in their drugs anonymously, to get them tested for what they contain, has started to increasingly detect it in other illicit drugs.
They only found nitazenes five times in 2021, but have discovered it 57 times so far this year. It was in what users thought was cannabis in Manchester and cannabis vape liquid in Portsmouth.
They’ve been found most often in what users thought were the black market versions of the anti-anxiety drug diazepam, and pain medication oxycodone, 21 times each.
They are even more dangerous to people who don’t already use opioids, and therefore have no tolerance.
The reported side effects include hallucinations, irregular heartbeat, chest pains, nosebleeds, vomiting, memory loss, aggression, and overdose.
Back on the streets of Whitechapel, another heroin addict, called Rebel, sits waiting for her methadone script outside a drug rehabilitation centre.
Drug user Rebel
She said heroin has changed. She hates the synthetics, describing them as a waste of money and said they don’t work, but she agrees that not knowing what she’s using makes life more dangerous. Health workers have run urine tests and warned her of other substances cut into her drugs.
“They text me and tell me something is cut in it – it’s really bad.” Rebel becomes emotional talking about the impact of her addiction. “I’m 60 now. I don’t want to die a junkie,” she said.
This week, 15 new synthetic opioids were categorised as Class A drugs by the government, but that doesn’t make them any easier for drug users to detect.
A dangerous market has become more deadly. Users like Rebel are rolling the dice every day.
UK
Police investigating alleged attack on prison officer by Southport triple murderer Axel Rudakubana
Schoolchildren are asking teachers how to strangle a partner during sex safely, a charity says, while official figures show an alarming rise in the crime related to domestic abuse cases.
Warning: This article contains references to strangulation, domestic abuse and distressing images.
It comes as a woman whose former partner almost strangled her to death in a rage has advised anyone in an abusive relationship to seek help.
Bernie Ryan, chief executive of the Institute for Addressing Strangulation, has been running the charity since its inception in 2022 after non-fatal strangulation became a standalone offence.
“It’s the ultimate form of control,” she says.
She says perpetrators and victims are getting younger, while the reason is unclear, but strangulation has seeped into popular culture and social media.
“We hear lots of sex education providers, teachers saying that they’re hearing it in schools.
“We know teachers have been asked, ‘how do I teach somebody to strangle safely?’
“Our message is there is no safe way to strangle – the anatomy is the anatomy. Reduction in oxygen to the brain or blood flow will result in the same medical consequences, regardless of context.”
Bernie Ryan, CEO of the Institute for Addressing Strangulation
A recent review by Conservative peer Baroness Gabby Bertin recommended banning “degrading, violent and misogynistic content” online.
Violent pornography showing women being choked during sex she found was “rife on mainstream platforms”.
Ms Ryan says she “wants to make sure that young people don’t have access to activities that demonstrate that this is normal behaviour”.
Read more from Sky News:
Suspect accused of Derby bank murder appears in court
Man whose body was found in suitcase ‘had raped teenager’
Strangulation is a violent act that is often committed in abusive relationships.
It is the second most common method used by men to kill women, the first is stabbing.
According to statistics shared by the Crown Prosecution Service, in 2024 there was an almost 50% rise in incidents of non-fatal strangulation and suffocation – compared to the year before.
Kerry Allan pleads for other victims of abuse to seek help
Domestic abuse victim Kerry Allan has a message for anyone who is in an abusive relationship.
Kerry met Michael Cosgrove in September 2022. While she said “at the beginning it was really good”, within months he became physically abusive.
In August last year her friends found his profile on a dating app.
“I confronted him and he denied it. I knew we were going to get into a big argument and I couldn’t face it, so I said I was going to my mum’s for a few days and take myself away from the situation.
“I came back a few days later and stupidly I agreed we could try again and everything escalated from that.”
Injuries to Kerry’s chest. Pic: CPS
In the early hours of 25 August the pair had come in from a night out at a concert and got into an argument.
“He was having a go at me, accusing me of flirting with other people, and I was angry. I told him he had a nerve after what he’d done to me in the week and how he humiliated me.
“I told him that I wanted to leave, that we were done and that I wanted to go to my mum’s and that’s when it got bad.
“He pinned me to the bed and that’s when he first strangled me.”
Kerry’s neck injury. Pic: CPS
Kerry says this was the first time she’d ever been violently assaulted. Cosgrove was eerily silent as he eventually let go and Kerry gasped for air.
“I remember trying to get my breath back, I was crying and hyperventilating… I was sick on the bedroom floor and I was asking him to go.”
Cosgrove strangled her for a second time before letting go again.
“He was saying I wasn’t getting out of this bedroom alive. I was dead tonight, he hoped that I knew that. Just kept saying how I’d ruined his life.”
Injury to Kerry’s eye. Pic: CPS
“I remember feeling a sort of shock thinking at this point, I’m not going to get out of this bedroom, he’s actually going to kill me.”
Kerry began screaming and shouting for help as loud as she could.
Her neighbours heard the commotion and called the police. While they were en route, Kerry was once again being assaulted.
Bleeding in Kerry’s eye
“I ran over to the bedroom window and tried to jump out, he grabbed me as I went to open the window, and we struggled. And then I was back in the same position, he was on top of me on the bed, and his hands were round the throat again. But this time it didn’t stop.
“I remember trying to struggle and trying to kick out and hit him and I just kept thinking that I definitely was going to die, because at this point, it wasn’t stopping.”
The next memory Kerry has is opening her eyes to see police and paramedics in the bedroom.
Michael Cosgrove. Pic: CPS
Cosgrove had heard the sirens, jumped out of the bedroom window and went to hide in Kerry’s car.
Kerry remembers opening her eyes to paramedics caring for her: “I remember thinking, I’m alive. I couldn’t believe it. I couldn’t believe that I was alive and I wasn’t dead. My last memory is him being on top of me with his hands on my throat.”
Kerry met Michael Cosgrove in September 2022
She gives this advice to anyone who is in an abusive relationship: “Please speak to somebody, whether it’s friends, family, a work colleague, whether it’s somebody online, whether it’s a charity that you’re directed to, any sort of abuse is not okay.
“Whether it starts off emotional, they often start off that way, and they escalate, and they can escalate badly.
“Take what happened to me as a huge warning sign, because I wouldn’t want anyone else to be in the position I’ve been in the last eight months.”
Cosgrove was found guilty of attempting to murder Kerry and intentional strangulation.
He will be sentenced in July.
If you suspect you are being abused and need to speak to someone, there are people who can help you.
The National Domestic Violence Helpline: 0808 2000 247
Respect, the helpline for male domestic abuse victims: 0808 8010327
Galop, the LGBT+ anti-violence charity: 0800 999 5428
Two men have been found guilty of cutting down the famous Sycamore Gap tree that stood for more than 150 years.
Daniel Graham and Adam Carruthers were convicted of causing more than £620,000 worth of damage to the tree and more than £1,000 worth of damage to Hadrian’s Wall in Northumberland.
On 27 September 2023, the pair drove 30 miles through a storm to Northumberland from Cumbria, where they both lived, before felling the tree overnight in a matter of minutes.
The Sycamore Gap tree before it was cut down. Pic: CPS
The pair each denied two counts of criminal damage to the sycamore and to Hadrian’s Wall, which was damaged when the tree fell on it, but were convicted by a jury at Newcastle Crown Court on Friday.
The Sycamore Gap tree sat in a dip in the landscape and held a place in pop culture, featuring in the 1991 Kevin Costner film Robin Hood: Prince of Thieves.
It also formed part of people’s personal lives, as the scene of wedding proposals, ashes being scattered and countless photographs.
Footage of the moment the tree was felled was played during the trial.
Daniel Graham. Pic: Northumbria Police/PA
Adam Carruthers. Pic: Northumbria Police/PA
In the clip, the sound of a chainsaw can be heard, and the silhouette of a person can be seen, before the trunk eventually tumbled.
The footage was shot on Graham’s iPhone 13, with the metadata providing the coordinates of the tree.
Part of tree kept as ‘trophy’
Over the course of the trial, the pair blamed one another, but the prosecution argued they were both responsible for what the court heard was a “mindless act of vandalism”.
As well as the video footage of the felling, an image of a piece of wood and a chainsaw was found on Graham’s phone.
Adam Carruthers (R) and Daniel Graham (L) worked together felling trees. Pic: CPS/PA
An image of a piece of wood and a chainsaw was found on Graham’s phone. Pic: PA
Richard Wright KC, prosecuting, told the court: “This was perhaps a trophy taken from the scene to remind them of their actions, actions that they appear to have been revelling in.”
Voice notes played in court
The jury was also played voice notes the pair had sent one another, commenting on the media coverage the incident was receiving.
In one of them, Graham, 39, said to 32-year-old Carruthers: “Someone there has tagged like ITV News, BBC News, Sky News, like News News News”, before adding: “I think it’s going to go wild.”
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Sycamore Gap seeds saved
Another piece of evidence was a photo of the defendants felling a different tree, about a month before the Sycamore Gap was cut down.
The prosecution said Graham, who owned a groundworks company and Carruthers, who worked in property management and mechanics, were “friends with knowledge and experience in chainsaws and tree felling”.
From the beginning, much of the trial focused on the significance of the tree, with Judge Mrs Justice Lambert telling the jury to put their “emotion to one side” before proceedings began.
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Voicenotes from Sycamore Gap tree trial
‘Mindless acts of violence’
Northumberland Superintendent Kevin Waring, of Northumbria Police, said: “We often hear references made to mindless acts of vandalism – but that term has never been more relevant than today in describing the actions of those individuals”.
Graham and Carruthers gave no explanation for why they targeted the tree, he said, “and there never could be a justifiable one”.
Northumbria Police and Crime Commissioner, Susan Dungworth, called the felling of the tree “unfathomable” and said, although “there was no remorse [from the defendants], there was compelling evidence, and now there will be justice”.
Gale Gilchrist, chief crown prosecutor for CPS North East, said Graham and Carruthers took “under three minutes” to bring down the “iconic landmark” in a “deliberate and mindless act of destruction”.
She said she hoped the community “can take some measure of comfort in seeing those responsible convicted”.
‘Enormity of the loss’
Reflecting on the verdict and the actions of the pair, Tony Gates, chief executive of Northumberland National Parks Authority, said: “It just took a few days to sink in – I think because of the enormity of the loss.
“We knew how important that location was for many people at an emotional level, almost at a spiritual level in terms of people’s connection to this case.”
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Moment Sycamore Gap tree cut down
Read more from the trial:
Two men went on ‘moronic mission’ to fell Sycamore Gap tree
Man told police he was being ‘framed’ over tree felling
Defendant says friend wanted to cut down world’s ‘most famous tree’
Jurors played voicenotes in Sycamore Gap tree trial
The tree’s stump still sits by Hadrian’s Wall, where new shoots have been emerging.
Its largest remaining section will go on display at the National Landscape Discovery Centre in the Northumberland National Park later this year.
The effort to preserve the tree’s legacy also goes beyond the region where it stood.
Forty-nine saplings taken from the tree have been conserved by the National Trust. They will be planted in accessible public spaces across the country as “trees of hope”, which will allow parts of the Sycamore Gap to live on.
The defendants, who didn’t react when the verdicts were delivered, will be sentenced in July.
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