Nitazenes: The new synthetic opioids stronger than heroin that are being cut into drugs
Charlotte, not her real name, wanders back and forth with her empty coffee cup held out towards the tide of commuters coming through the barriers.
Rush hour at Whitechapel underground station is the best time of day for the small, frail, 23-year-old to earn enough change to pay for her next hit.
She’s agitated, but for the briefest moment agrees to talk. I ask if any symptoms from her drug use have changed recently. “I’ve got holes in my legs,” she says. “There’s no skin, just holes. It’s painful.”
Synthetic opioids seized by officers. Pic: Met Police
Her legs are bandaged. She says the strange bores in her flesh have only appeared in the last few months and is unsure why.
But drug charity workers are convinced this is a symptom of a terrifying evolution in the drug market – a growing prevalence of dangerous synthetic opioids being cut into drugs like heroin.
The deadliest, nitazenes, are the newest killer on the streets.
“I’m seeing people coughing up blood. I’m seeing people dying,” says crack cocaine user Rory, who we meet in Aldgate in East London.
“Any drug you are buying off the street you’re taking a risk. These people are in it for the money and the purer it is, the less they make – so they are putting other stuff in it.”
Crack cocaine user Rory
The opioid fentanyl is 50 times stronger than heroin and is the primary drug in North America, where synthetic opioids are estimated to have caused 75,000 deaths in the US last year.
Nitazenes have similar properties to fentanyl, but can be up to 300 times stronger than heroin. Only this week, several have been classified as Class A drugs.
First detected in the UK from a sample of white powder found in the back of a taxi in Wakefield in April 2021, nitazenes have since been found in heroin, cannabis, cocaine, in a vape and most prevalently in black market pills sold as the anti-anxiety drug diazepam.
‘Substantial risk of overdose, hospitalisation, and death’
In October, a police raid on a “sophisticated factory” in Waltham Forest recovered approximately 150,000 nitazene tablets, the largest-ever recovered stash of synthetic opioids. Eleven people were arrested.
Detective Superintendent Helen Rance, who is leading the investigation, said: “Synthetic opioids have been detected in batches of heroin found in London and across the UK; they substantially raise the risk of incredibly serious harm to the user and are believed to be linked to a number of deaths.”
Recently, the opioid is thought to have been cut into a batch of drugs in Dublin, causing 57 people to overdose within a few days.
Professor Eamon Keenan, from the Health Safety Executive, said: “These pose a substantial risk of overdose, hospitalisation, and death.”
Meg Jones, director of social justice charity Cranstoun, said: “We are seeing nitazenes pop up in pockets all over the UK and it is incredibly concerning.”
She added: “There are an increasing number of synthetic opioids being detected in drugs that people thought were very different. We need to see government action quickly on this, because we are sleepwalking into what I would deem to be a public health crisis, and we are not prepared for it in the UK at all.”
Action means more testing and provision of drugs that can counter the effects of opioid overdose.
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Outreach worker Abdirahim Hassan, founder of East London community group Coffee Afrik, agrees. He showed me a video of a young woman who appears to have overdosed. She is slumped unconscious on the pavement in Whitechapel.
Outreach worker Abdirahim Hassan
Her body is in the prayer position, her torso flat over her knees, her face pressed against the ground. “She’s just frozen. Her eyes are closed, and people are just walking past,” said Abdirahim. “She’s a young woman, maybe 24, somebody’s daughter.”
Abdirahim said a crackdown on heroin production by the Taliban has successfully stemmed the flow of heroin from Afghanistan which had previously provided 95% of the UK heroin market. That’s led to a boom in the easier to produce, more deadly synthetics.
“What it means is there’s a much higher risk of overdose and death,” he said. “But it’s a cheaper product and more potent so people are in greater crisis and there is not enough testing.”
Birmingham also saw a spike in the detection of nitazenes. Sky News was given access to a unique project in West Midlands police cells, run by the charity Cranstoun.
Steve Whitby is a drug and alcohol worker who visits suspects in their cells. The idea is that drug rehabilitation services reach out to offer support to addicts while they are in police custody.
Drug and alcohol worker Steve Whitby is interviewed by Farrell
On one cell visit, Steve warns an addict, who is also a suspected shoplifter, about the dangers of nitazenes. He told him: “So these are synthetic drugs that dealers are putting into heroin – but it’s causing lots of people to die from overdose.”
He told the man he shouldn’t take drugs alone and that he will leave a kit with his belongings which includes two syringes of naloxone, an antidote of opioid overdose. He explained the man will have to teach whoever is with him how to use it.
Naxolone is a treatment for people who have overdosed
This pilot in Birmingham is believed to be the first time naloxone has been given to addicts in custody, and the charity said this needs to become a national provision.
The Cranstoun programme in police custody suites is funded by the West Midlands police and crime commissioner.
“In essence, this saves more lives than any other intervention,” said Steve as he demonstrated how to inject the clear liquid into the side of the thigh.
He said sometimes it’s dispensed to the children of addicts so they can save their parents lives if they overdose.
As such a newcomer to the UK market and often concealed as something else, there is little data about the prevalence of nitazenes.
Pic: Met Police
The opioid is even more dangerous for those who have never taken it before
However, Wedinos, a service based in Wales where people can send in their drugs anonymously, to get them tested for what they contain, has started to increasingly detect it in other illicit drugs.
They only found nitazenes five times in 2021, but have discovered it 57 times so far this year. It was in what users thought was cannabis in Manchester and cannabis vape liquid in Portsmouth.
They’ve been found most often in what users thought were the black market versions of the anti-anxiety drug diazepam, and pain medication oxycodone, 21 times each.
They are even more dangerous to people who don’t already use opioids, and therefore have no tolerance.
The reported side effects include hallucinations, irregular heartbeat, chest pains, nosebleeds, vomiting, memory loss, aggression, and overdose.
Back on the streets of Whitechapel, another heroin addict, called Rebel, sits waiting for her methadone script outside a drug rehabilitation centre.
Drug user Rebel
She said heroin has changed. She hates the synthetics, describing them as a waste of money and said they don’t work, but she agrees that not knowing what she’s using makes life more dangerous. Health workers have run urine tests and warned her of other substances cut into her drugs.
“They text me and tell me something is cut in it – it’s really bad.” Rebel becomes emotional talking about the impact of her addiction. “I’m 60 now. I don’t want to die a junkie,” she said.
This week, 15 new synthetic opioids were categorised as Class A drugs by the government, but that doesn’t make them any easier for drug users to detect.
A dangerous market has become more deadly. Users like Rebel are rolling the dice every day.
Former Manchester United and Scotland footballer Denis Law has died, at the age of 84.
In a statement, his family said: “It is with a heavy heart that we tell you our father Denis Law has sadly passed away. He fought a tough battle, but finally, he is now at peace.
“We would like to thank everyone who contributed to his wellbeing and care, past and much more recently.
“We know how much people supported and loved him and that love was always appreciated and made the difference.”
Denis Law in 2005. Pic: PA
The Aberdeen-born footballer previously announced in August 2021 that he had been diagnosed with dementia.
A prolific striker, Law scored 237 goals in 404 appearances for Manchester United, for whom he signed for a then-British record transfer fee in 1962.
He is the only man to have two statues dedicated to him at Old Trafford – one on the Stretford End concourse, the other as part of the United Trinity statue overlooking the stadium’s forecourt beside fellow great George Best and Sir Bobby Charlton.
Denis Law, third from left, as a statue featuring him alongside Sir Bobby Charlton and George Best – known as the ‘holy trinity’ – was unveiled in 2008. Pic: AP
The only Scottish player to have won the Ballon d’Or award, in 1964, he was also part of United’s triumphant campaign in the 1968 European Cup – in which they became the first English club to ever win the competition.
In a statement, the club said: “Everyone at Manchester United is mourning the loss of Denis Law, the King of the Stretford End, who has passed away, aged 84.
“He will always be celebrated as one of the club’s greatest and most beloved players.
Denis Law, centre, during Manchester United’s triumphant European Cup campaign in 1968. Pic: AP
“The ultimate goalscorer, his flair, spirit and love for the game made him the hero of a generation. Our deepest condolences go out to Denis’s family and many friends. His memory will live on forever more.”
Wayne Rooney, former United captain and the club’s all-time record goalscorer, described Law as a “legend”.
“Thoughts with all Denis’s family and friends,” he said in an online post.
Another former United captain, Gary Neville, said: “A great footballer and a great man. It’s a privilege and an honour to have spent time in your company. The King of the Stretford End.”
A tribute from the Scotland national team said Law was “a true great”.
“We will not see his likes again,” it said.
Law also played for Huddersfield Town, Manchester City, and Italian club Torino during his club career, and made 55 appearances for Scotland, scoring 30 goals for his country.
Manchester City said in a post on X: “The whole of Manchester, including everyone at City, is mourning with you. Rest in peace, Denis.”
The UK’s benchmark stock index has reached another record high.
The FTSE 100 index of most valuable companies on the London Stock Exchange closed at 8,505.69, breaking the record set last May.
It had already broken its intraday high at 8532.58 on Friday afternoon, meaning it reached a high not seen before during trading hours.
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The weakened pound has boosted many of the 100 companies forming the top-flight index.
Why is this happening?
Most are not based in the UK, so a less valuable pound means their sterling-priced shares are cheaper to buy for people using other currencies, typically US dollars.
This makes the shares better value, prompting more to be bought. This greater demand has brought up the prices and the FTSE 100.
The pound has been hovering below $1.22 for much of Friday. It’s steadily fallen from being worth $1.34 in late September.
Also spurring the new record are market expectations for more interest rate cuts in 2025, something which would make borrowing cheaper and likely kickstart spending.
What is the FTSE 100?
The index is made up of many mining and international oil and gas companies, as well as household name UK banks and supermarkets.
Familiar to a UK audience are lenders such as Barclays, Natwest, HSBC and Lloyds and supermarket chains Tesco, Marks & Spencer and Sainsbury’s.
Other well-known names include Rolls-Royce, Unilever, easyJet, BT Group and Next.
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FTSE stands for Financial Times Stock Exchange.
If a company’s share price drops significantly it can slip outside of the FTSE 100 and into the larger and more UK-based FTSE 250 index.
The inverse works for the FTSE 250 companies, the 101st to 250th most valuable firms on the London Stock Exchange. If their share price rises significantly they could move into the FTSE 100.
A good close for markets
It’s a good end of the week for markets, entirely reversing the rise in borrowing costs that plagued Chancellor Rachel Reeves for the past ten days.
Fears of long-lasting high borrowing costs drove speculation she would have to cut spending to meet self-imposed fiscal rules to balance the budget and bring down debt by 2030.
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They Treasury tries to calm market nerves late last week
Long-term government borrowing had reached a high not seen since 1998 while the benchmark 10-year cost of government borrowing, as measured by 10-year gilt yields, was at levels last seen around the 2008 financial crisis.
The gilt yield is effectively the interest rate investors demand to lend money to the UK government.
Only the pound has yet to recover the losses incurred during the market turbulence. Without that dropped price, however, the FTSE 100 record may not have happened.
Also acting to reduce sterling value is the chance of more interest rates. Currencies tend to weaken when interest rates are cut.
UK
Nazi-obsessed terrorist Callum Parslow jailed after trying to murder asylum seeker at Worcestershire hotel
A Nazi-obsessed man has been jailed for attempted murder after he stabbed an asylum seeker in a terrorist attack.
Callum Parslow was handed a life sentence and will serve a minimum of 22 years and eight months in prison after he knifed the man at a Worcestershire hotel on 2 April last year, as a “protest” against small boat crossings.
The victim, Nahom Hagos, from Eritrea, said it was a “miracle” he survived after being stabbed in the chest and hand.
Parslow, 32, has Hitler’s signature tattooed on his arm and used a £770 knife he had bought online to attack Mr Hagos when he was eating in the conservatory of the Pear Tree Inn at Hindlip.
During sentencing, the judge, Mr Justice Dove, told Parslow: “You committed a vicious and unprovoked assault on a complete stranger Nahom Hagos who suffered devastating injuries as a result of your violence.”
The judge also said Parslow, from Worcester, was “motivated by your adoption of a far-right neo-Nazi mindset which fuelled your warped, violent and racist views”, and added: “This was undoubtedly a terrorist attack.”
He was found guilty of attempted murder in October last year.
Callum Parslow. Pic: West Midlands Police/PA
Leicester Crown Court heard at the time that Mr Hagos, who used to live at the hotel, was visiting a friend and was stabbed after Parslow asked him for directions to the toilet.
CCTV from the scene showed Mr Hagos fleeing to a car park and being chased by Parslow. He was able to run back into the main reception area, where the hotel manager locked the front door.
Parslow later re-entered through another door apparently searching for further victims, the court heard.
The hotel manager and a builder used a van to take Mr Hagos to hospital in Worcester, as they felt he was losing too much blood, where he was found to have an 8cm-long wound which had not penetrated any of his vital organs.
After trying to kill Mr Hagos, Parslow ran towards a canal and was spotted with what appeared to be blood on his hands.
Officers found blood containing a DNA profile matching that of the victim on the blade of the knife abandoned by Parslow.
The knife belonging to Parslow. Pic: West Midlands Police/PA
Failed manifesto post
After the stabbing and as police closed in, Parslow tried to post a “terrorist manifesto” on X, tagging Tommy Robinson and politicians including Nigel Farage, Suella Braverman and Sir Keir Starmer.
He wrote that he “just did my duty to England” and had tried to “exterminate” Mr Hagos. However, it failed to send as he copied in too many people.
Others on his list included Laurence Fox, Lee Anderson, Boris Johnson, Donald Trump and various news organisations.
Nazi memorabilia at bedsit
During the trial last October, the court heard an axe, metal baseball bat and a second knife were found at Parslow’s bedsit in Bromyard Terrace in Worcester.
Police also discovered a swastika armband, a Nazi-era medallion and copies of Hitler’s book Mein Kampf.
Nazi memorabilia which was seized at Parslow’s bedsit in Worcester. Pics: West Midlands Police/PA
Jurors were also told Parslow had Hitler’s signature tattooed on his arm “in order to demonstrate his affiliation to the ideals of the leader of the German Nazi party”.
He also pleaded guilty to an unconnected sexual offence and two charges of sending electronic communications with intent to cause distress and anxiety at the time.
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‘The pain feels unbearable’
Mr Hagos told the court in an impact statement he continues to feel “excruciating pain” in his hand after the attack by Parslow.
Read out by the prosecution on Friday, he said: “The pain is unbearable and keeps me awake all night long.
“The pain feels like an electric shock going through my hand and I now have insomnia.”
He then said he had been “living and pursuing a happy life before the incident,” but added: “I feel lonely and don’t feel safe on the street.
“My life has been turned upside down.”
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