Friends star Matthew Perry’s death was an accident from the “acute effects of ketamine”, a post-mortem has found.
Perry, who was best known for playing wise-cracking Chandler Bing in Friends, was found unresponsive in the swimming pool at this home on 28 October and pronounced dead at the age of 54 by paramedics at the scene.
Other contributing factors to his death included drowning, coronary artery disease and the effects of buprenorphine, which can be used to treat opioid use disorder, the post-mortem said.
Ketamine is a sedative that can be used to treat depression.
A report from the Los Angeles Department of Medical Examiner stated that Perry was “receiving ketamine infusion therapy for depression and anxiety” with the most recent dose reportedly taken one and a half weeks before his death.
The report continued: “The ketamine in his system at death could not be from that infusion therapy, since ketamine’s half-life is three-to-four hours, or less.”
Image: Perry with Friends co-stars Lisa Kudrow, Courteney Cox and Jennifer Aniston
The post-mortem reports states that ketamine is a “dissociative anaesthetic with established human medical and surgical uses”.
Originally designed as an anaesthetic and tranquilliser, often used on horses during veterinary surgery, ketamine was banned as a recreational drug in 2006 and in now class B.
It reduces sensations in the body and gives users a “floating” feeling but can also cause hallucinations, confusion, panic attacks and depression.
It wasn’t until the 90s that ketamine started to be widely used by young people involved in the
dance music scene.
It is used orally in tablet form, intra-nasally as a powder, or intravenously and intramuscularly as a liquid.
Ketamine can also work as an antidepressant but has not been licensed for this use in the UK.
Aniston, who played Rachel Green in the sitcom, was among those urging support of the foundation which was set up to “honour his legacy”.
Perry’s cause of death comes days after Aniston revealed she had been messaging him on the morning of his death, describing him as “happy and healthy”.
“I want people to know he was really healthy, and getting healthy. He was on a pursuit. He worked so hard. He really was dealt a tough one,” she told Variety.
A man has been arrested on suspicion of assault and sexual assault – which reportedly took place on the set of EastEnders.
The alleged incident happened on the set of the BBC soap at Elstree Studios in Hertfordshire, according to The Sun newspaper.
Hertfordshire Police confirmed a man in his 50s was arrested after the report in Eldon Avenue, Borehamwood, on 7 May.
The man is accused of sexual assault and common assault in relation to two victims, the force said.
The suspect is on bail while inquiries continue, police added.
EastEnders said in a statement: “While we would never comment on individuals, EastEnders has on-site security and well-established procedures in place to safeguard the safety and welfare of everyone who works on the show.”
BST Hyde Park festival has cancelled its final night after Jeff Lynne’s Electric Light Orchestra pulled out of the headline slot.
Lynne, 77, was due to play alongside his band on Sunday but has been forced to withdraw from the event following a “systemic infection”.
The London show was supposed to be a “final goodbye” from ELO following their farewell US tour.
Organisers said on Saturday that Lynne was “heartbroken” at being unable to perform.
A statement read: “Jeff has been battling a systemic infection and is currently in the care of a team of doctors who have advised him that performing is simply not possible at this time nor will he be able to reschedule.
“The legacy of the band and his longtime fans are foremost in Jeff’s mind today – and while he is so sorry that he cannot perform, he knows that he must focus on his health and rehabilitation at this time.”
They later confirmed the whole of Sunday’s event would be cancelled.
“Ticket holders will be refunded and contacted directly by their ticket agent with further details,” another statement said.
Stevie Wonder played the festival on Saturday – now its final event of 2025.
US rock band The Doobie Brothers and blues rock singer Steve Winwood were among those who had been due to perform to before ELO’s headline performance.
The cancellation comes after the band, best known for their hit Mr Blue Sky, pulled out of a performance due to take place at Manchester’s Co-Op Live Arena on Thursday.
ELO was formed in Birmingham in 1970 by Lynne, multi-instrumentalist Roy Wood and drummer Bev Bevan.
They first split in 1986, before frontman Lynne resurrected the band in 2014.
Donald Trump has said he is considering “taking away” the US citizenship of actress and comedian Rosie O’Donnell, despite a Supreme Court ruling that expressly prohibits a government from doing so.
In a post on Truth Social on Saturday, the US president said: “Because of the fact that Rosie O’Donnell is not in the best interests of our Great Country, I am giving serious consideration to taking away her Citizenship.”
He also labelled O’Donnell, who has moved to Ireland, as a “threat to humanity” and said she should “remain in the wonderful country of Ireland, if they want her”.
O’Donnell responded on Instagram by posting a photograph of Mr Trump with Jeffrey Epstein.
“You are everything that is wrong with America and I’m everything you hate about what’s still right with it,” she wrote in the caption.
“I’m not yours to silence. I never was.”
Image: Rosie O’Donnell moved to Ireland after Donald Trump secured a second term. Pic: AP
O’Donnell moved to Ireland with her 12-year-old son in January after Mr Trump had secured a second term.
She has said she’s in the process of obtaining Irish citizenship based on family lineage and that she would only return to the US “when it is safe for all citizens to have equal rights there in America”.
O’Donnell and the US president have criticised each other publicly for years, in an often-bitter back-and-forth that predates Mr Trump’s move into politics.
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This is just the latest threat by the president to revoke the citizenship of someone he has disagreed with, most recently his former ally Elon Musk.
But the two situations are different as while Musk was born in South Africa, O’Donnell was born in the US and has a constitutional right to American citizenship.
Amanda Frost, a law professor at the University of Virginia School of Law, said the Supreme Court ruled in a 1967 case that the fourteenth amendment of the constitution prevents the government from taking away citizenship.
“The president has no authority to take away the citizenship of a native-born US citizen,” he added.
“In short, we are nation founded on the principle that the people choose the government; the government cannot choose the people.”