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Friends star Matthew Perry’s death was an accident from the “acute effects of ketamine”, a post-mortem has found.

Perry, who was best known for playing wise-cracking Chandler Bing in Friends, was found unresponsive in the swimming pool at this home on 28 October and pronounced dead at the age of 54 by paramedics at the scene.

Other contributing factors to his death included drowning, coronary artery disease and the effects of buprenorphine, which can be used to treat opioid use disorder, the post-mortem said.

Ketamine is a sedative that can be used to treat depression.

A report from the Los Angeles Department of Medical Examiner stated that Perry was “receiving ketamine infusion therapy for depression and anxiety” with the most recent dose reportedly taken one and a half weeks before his death.

The report continued: “The ketamine in his system at death could not be from that infusion therapy, since ketamine’s half-life is three-to-four hours, or less.”

Matthew Perry with Friends co-stars Lisa Kudrow, Courteney Cox and Jennifer Aniston
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Perry with Friends co-stars Lisa Kudrow, Courteney Cox and Jennifer Aniston

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Perry appeared in the hit US show, which is set in New York between 1994 and 2004.

Tributes poured in for Perry in the days after his death, including from his co-stars.

What is ketamine?

The post-mortem reports states that ketamine is a “dissociative anaesthetic with established human medical and surgical uses”.

Originally designed as an anaesthetic and tranquilliser, often used on horses during veterinary surgery, ketamine was banned as a recreational drug in 2006 and in now class B.

It reduces sensations in the body and gives users a “floating” feeling but can also cause hallucinations, confusion, panic attacks and depression.

It wasn’t until the 90s that ketamine started to be widely used by young people involved in the
dance music scene.

It is used orally in tablet form, intra-nasally as a powder, or intravenously and intramuscularly as a liquid.

Ketamine can also work as an antidepressant but has not been licensed for this use in the UK.

Friends actors Matt LeBlanc, Jennifer Aniston, Courteney Cox, David Schwimmer and Lisa Kudrow, were also among the 20 mourners at Perry’s funeral in the Hollywood Hills in November.

Perry was open about his battle with substance abuse and addiction, and set up a sober living facility for men with similar issues.

A foundation has now been set up to help others struggling with the disease in his memory.

Matthew Perry
Image:
Perry in 2017

Aniston, who played Rachel Green in the sitcom, was among those urging support of the foundation which was set up to “honour his legacy”.

Perry’s cause of death comes days after Aniston revealed she had been messaging him on the morning of his death, describing him as “happy and healthy”.

“I want people to know he was really healthy, and getting healthy. He was on a pursuit. He worked so hard. He really was dealt a tough one,” she told Variety.

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Two dead after multiple people were injured in shooting at church in Kentucky

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Two dead after multiple people were injured in shooting at church in Kentucky

Two people are dead after multiple people were injured in shootings in Kentucky, the state’s governor has said.

Andy Beshear said the suspect had also been killed following the shooting at Richmond Road Baptist Church in Lexington.

A state trooper was earlier shot at Blue Grass Airport in Fayette County on Sunday morning, the Lexington Herald-Leader local newspaper reports.

Mr Beshear has said a state trooper “from the initial stop” and people who were injured in the church shooting are “being treated at a nearby hospital”.

The extent of the injuries is not immediately known.

State troopers and the Lexington Police Department had caught up with the suspect at the church following the shooting in Fayette County, according to Sky News’ US partner network NBC News.

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Mr Beshear said: “Please pray for everyone affected by these senseless acts of violence, and let’s give thanks for the swift response by the Lexington Police Department and Kentucky State Police.”

The Blue Grass Airport posted on X at 1pm local time (6pm UK time) that a law enforcement investigation was impacting a portion of an airport road, but that all flights and operations were now proceeding normally.

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Donald Trump threatens to revoke Rosie O’Donnell’s US citizenship

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Donald Trump threatens to revoke Rosie O'Donnell's US citizenship

Donald Trump has said he is considering “taking away” the US citizenship of actress and comedian Rosie O’Donnell, despite a Supreme Court ruling that expressly prohibits a government from doing so.

In a post on Truth Social on Saturday, the US president said: “Because of the fact that Rosie O’Donnell is not in the best interests of our Great Country, I am giving serious consideration to taking away her Citizenship.”

He also labelled O’Donnell, who has moved to Ireland, as a “threat to humanity” and said she should “remain in the wonderful country of Ireland, if they want her”.

O’Donnell responded on Instagram by posting a photograph of Mr Trump with Jeffrey Epstein.

“You are everything that is wrong with America and I’m everything you hate about what’s still right with it,” she wrote in the caption.

“I’m not yours to silence. I never was.”

Rosie O'Donnell arrives at the ELLE Women in Hollywood celebration on Tuesday, Nov. 19, 2024, in Los Angeles. (Photo by Jordan Strauss/Invision/AP)
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Rosie O’Donnell moved to Ireland after Donald Trump secured a second term. Pic: AP

O’Donnell moved to Ireland with her 12-year-old son in January after Mr Trump had secured a second term.

She has said she’s in the process of obtaining Irish citizenship based on family lineage and that she would only return to the US “when it is safe for all citizens to have equal rights there in America”.

O’Donnell and the US president have criticised each other publicly for years, in an often-bitter back-and-forth that predates Mr Trump’s move into politics.

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This is just the latest threat by the president to revoke the citizenship of someone he has disagreed with, most recently his former ally Elon Musk.

But the two situations are different as while Musk was born in South Africa, O’Donnell was born in the US and has a constitutional right to American citizenship.

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Amanda Frost, a law professor at the University of Virginia School of Law, said the Supreme Court ruled in a 1967 case that the fourteenth amendment of the constitution prevents the government from taking away citizenship.

“The president has no authority to take away the citizenship of a native-born US citizen,” he added.

“In short, we are nation founded on the principle that the people choose the government; the government cannot choose the people.”

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Farmer becomes first person to die during Trump’s ICE raids

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Farmer becomes first person to die during Trump's ICE raids

A farmer who fell from a greenhouse roof during an anti-immigrant raid at a licensed cannabis facility in California this week has died of his injuries.

Jaime Alanis, 57, is the first person to die as a result of Donald Trump’s Immigration Compliance and Enforcement (ICE) raids.

His niece, Yesenia Duran, posted on the fundraising site GoFundMe to say her uncle was his family’s only provider and he had been sending his earnings back to his wife and daughter in Mexico.

The United Food Workers said Mr Alanis had worked on the farm for 10 years.

“These violent and cruel federal actions terrorise American communities, disrupt the American food supply chain, threaten lives and separate families,” the union said in a recent statement on X.

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Who is being targeted in Trump’s immigration raids?

The Department of Homeland Security (DHS) said it executed criminal search warrants at Glass House Farms facilities on Thursday.

Mr Alanis called family to say he was hiding and possibly fleeing agents before he fell around 30ft (9m) from the roof and broke his neck, according to information from family, hospital and government sources.

Agents arrested 200 people suspected of being in the country illegally and identified at least 10 immigrant children on the sites, the DHS said in a statement.

Mr Alanis was not among them, the agency said.

“This man was not in and has not been in CBP (Customs and Border Protection) or ICE custody,” DHS assistant secretary for public affairs Tricia McLaughlin said.

“Although he was not being pursued by law enforcement, this individual climbed up to the roof of a greenhouse and fell 30ft. CBP immediately called a medivac to the scene to get him care as quickly as possible.”

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Four US citizens were arrested during the incident for allegedly “assaulting or resisting officers”, the DHS said, and authorities were offering a $50,000 reward for information leading to the arrest of a person suspected of firing a gun at federal agents.

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In a statement, Glass House, a licensed Cannabis grower, said immigration agents had valid warrants. It said workers were detained and it is helping provide them with legal representation.

“Glass House has never knowingly violated applicable hiring practices and does not and has never employed minors,” it added.

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