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The partners of European venture capital firm Plural, from left to right: Ian Hogarth, Taavet Hinrikus, Carina Namih, Sten Tamkivi and Khaled Helioui.

Plural

The founders of Wise, Skype and Songkick have raised 400 million euros ($436.4 million) for a new fund to back technology startups in Europe. It seeks to compete with established funds like Atomico, Balderton Capital and Creandum with its founder-led focus.

Plural Fund II, the firm’s second to date, arrives just 18 months after the firm raised its last fund, a 250 million-euro vehicle. Its co-founders include Taavet Hinrikus, co-founder of fintech firm Wise, Ian Hogarth, co-founder of concert discovery service Songkick, Sten Tamkivi, co-founder of communications platform Skype, and Khaled Helioui, former CEO of Bigpoint Games.

Hinrikus told CNBC that Plural could serve as a better partner to startups in Europe than most venture capital funds, given that it was started by people with the “scar tissue” of proven entrepreneurs. Only 8% of VCs in Europe are former founders, he says, much lower than the 60% in the United States.

“If we look at a lot of VC funds, you have lots of people who have done great work with spreadsheets, not with startup life,” Hinrikus told CNBC in an interview. “In our case, it is seen as a core criteria for choosing our partners that they’re totally unemployable.”

“It feels like it’s world war three, and we’re in the trenches together as one of the founders. So, if we look at the track record, and our ability to get the deals done, I think that all seems to say that this is really missing in Europe,” Hinrikus added.

Plural raised the funds from a mix of limited partners, including British and American university endowments, U.S. foundations and insurers, strategic family offices in Europe and the United States. The firm said it saw “significant appetite” from LPs — limited partners, the institutional backers of venture funds — for its new fund and exceeded its own fundraising target, despite being in the “toughest environment” for raising a fund.

“The fact that, in a difficult fundraising environment, we’ve been able to raise a fund of this scale, with a huge amount of appetite from LPs, just shows you that some of the most sophisticated investors in the world are really recognising the opportunity in Europe, and really want to see a fund the shape of Plural,” Carina Namih, partner at Plural, told CNBC in an interview.

“I think it’s a real testament against the sort of macro backdrop that we’ve raised a fund of this size and scale so quickly,” she added.

The ‘unemployables’

Plural plans to invest at a pace of two to three investments per investor per year with its new fund. The firm has five partners in total, whom it dubs the “unemployables,” owing to the fact that they wouldn’t readily join a VC firm, or be employable at a startup. Each of the partners is an active angel investor.

Plural has made 27 investments in total, backing companies including law-focused artificial intelligence firm Robin AI, nuclear fusion power plant developer Proxima Fusion, and most recently drug discovery platform Sano Genetics. Its largest sectors by investment are AI (31%), frontier technology (16%), and climate and energy (14%).

Companies that can bundle AI with their current products will succeed, says Degas Wright

Hinrikus said Plural isn’t interested in finding the next major software-as-a-service name in Europe, referring to companies that make software for businesses to ease the burden of storing data, accessing infrastructure, and carrying out data analytics. It’s more interested in deep tech, focusing on founders looking to solve fundamental scientific problems around energy, unlock AI “superpowers,” and make groundbreaking progress in health care.

Building tech giants in Europe

Plural says it wants to build technology giants in Europe, identifying winners in emerging categories that other funds may tend to ignore, such as deep tech and clean tech.

Carina Namih, a biotechnology entrepreneur-turned-partner at Plural, said she wouldn’t be surprised to see major technology names on a par with U.S. and Chinese giants start to emerge in Europe in the not-too-distant future.

She noted technological breakthroughs are happening much faster now, boosted by key developments around AI and more established pools of capital. 

“Look at how quickly OpenAI burst onto the scene with ChatGPT,” she said, adding it’s taking shorter amounts of time for new technologies to hit major milestones. “Clearly, the big tech companies have a lot of advantages and are entrenched in many ways. But I think now is a time more than ever, where new players and emerging players can come in and dominate entirely new spaces that didn’t exist a year ago.”

Namih previously worked on applying AI to mRNA-based medicine at her former startup HelixNano.

Plural’s new fund launch adds to the wave of startup activity that’s been happening in Europe in the last decade or so. 

A report from venture capital firm Accel late last year showed that $1 billion-plus unicorn firms often serve as catalysts for startup creation, with 1,451 new startups being founded by former employees of European and Israeli unicorns.

Of that new batch of startups, a great deal of them tend to come from fintechs, according to the report, with 70 fintech unicorns producing 423 startups.

“In the last 10 years, the whole ecosystem really has become an ecosystem, whereas before, we were just wild game hunting,” Harry Nelis, partner at Accel, told CNBC. “There was one here, one there, there was no ecosystem.”

“It’s a lot easier to start a company than before. The engineering has been done before, the marketing has been done before,” he added. “That is a flywheel that we have never had in Europe, that we now do have.”

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Bitcoin accelerates its slide, falling toward $90,000 to start the week

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Bitcoin accelerates its slide, falling toward ,000 to start the week

Dado Ruvic | Reuters

Bitcoin briefly dropped below the $90,000 mark on Monday, extending its slide as investors continue to dump growth oriented assets like crypto and tech stocks.

The price of the flagship cryptocurrency was last lower by 3% at $91,358.66 to start the week, according to Coin Metrics. Earlier, it fell as low as $89,259.00. Bitcoin is down 10% in the past week.

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Bitcoin extends its slide as growth-oriented assets continue to get hit

Ether lost 7% Monday and the broader crypto market, as measured by the CoinDesk 20 index, dropped more than 5%. Shares of Coinbase and MicroStrategy slid 4% and 3%, respectively. Mara Holdings declined 4% and Core Scientific retreated by 2%.

Crypto assets’ decline began last week after stronger-than-expected payroll numbers caused a spike in bond yields and amid concerns about President-elect Donald Trump’s tariff plans – both of which gave a boost to the dollar while pressuring bitcoin and other risk assets.

“The need for liquidity is caused by FX spikes because of strong end-of-year U.S. economy number, the stock market rallying strong, and there are other places money is needed in the short-term,” said James Davies, co-founder and CEO at crypto trading platform Crypto Valley Exchange. “If we want bitcoin to act like a currency, we need to accept when it does, and this is one of those times. The U.S. Dollar has gotten stronger ad everything else including bitcoin is weaker when measured in dollars.”

Investor sentiment was optimistic coming into 2025, with markets looking forward to having a pro-crypto Congress and White House. That hope had outweighed any concern about macroeconomic-related speedbumps, until last week.

Investors are now warning that the first quarter of this year could be more turbulent for crypto than previously anticipated.

Bitcoin’s price grew 120% in 2024 but is down 3% so far in the new year.

Don’t miss these cryptocurrency insights from CNBC Pro:

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New AI tool for fighting health insurance denials could save hospitals billions, and help patients

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New AI tool for fighting health insurance denials could save hospitals billions, and help patients

The Waystar team celebrates its IPO at the Nasdaq

2024 Nasdaq, Inc. / Vanja Savic

Health-care payments company Waystar on Monday announced a new generative artificial intelligence tool that can help hospitals quickly tackle one of their most costly and tedious responsibilities: fighting insurance denials. 

Hospitals and health systems spend nearly $20 billion a year trying to overturn denied claims, according to a March report from the group purchasing organization Premier. 

“We think if we can develop software that makes people’s lives better in an otherwise stressful moment of time when they’re getting health-care, then we’re doing something good,” Waystar CEO Matt Hawkins told CNBC.

Waystar’s new solution, called AltitudeCreate, uses generative AI to automatically draft appeal letters. The company said the feature could help providers drive down costs and spare them the headache of digging through complex contracts and records to put the letters together manually. 

Hawkins led Waystar through its initial public offering in June, where it raised around $1 billion. The company handled more than $1.2 trillion in gross claims volume in 2023, touching about 50% of patients in the U.S. 

Claim denials have become a hot-button issue across the nation following the deadly shooting of UnitedHealthcare CEO Brian Thompson in December. Americans flooded social media with posts about their frustrations and resentment toward the insurance industry, often sharing stories about their own negative experiences. 

Read more CNBC reporting on AI

When a patient receives medical care in the U.S., it kicks off a notoriously complex billing process. Providers like hospitals, health systems or ambulatory care facilities submit an invoice called a claim to an insurance company, and the insurer will approve or deny the claim based on whether or not it meets the company’s criteria for reimbursement. 

If a claim is denied, patients are often responsible for covering the cost out-of-pocket. More than 450 million claims are denied each year, and denial rates are rising, Waystar said. 

Providers can ask insurers to reevaluate claim denials by submitting an appeal letter, but drafting these letters is a time-consuming and expensive process that doesn’t guarantee a different outcome.

Hawkins said that while there’s been a lot of discussion around claims denials recently, AltitudeCreate has been in the works at Waystar for the last six to eight months. The company announced an AI-focused partnership with Google Cloud in May, and automating claims denials was one of the 12 use cases the companies planned to explore.

Waystar has also had a denial and appeal management software module available for several years, Hawkins added.

AltitudeCreate is one tool available within a broader suite of Waystar’s AI offerings called AltitudeAI, which the company also unveiled on Monday. AltitudeCreate rolled out to organizations that are already using Waystar’s denial and appeal management software modules earlier this month at no additional cost, the company said. 

Waystar plans to make the feature more broadly available in the future. 

“In the face of all of this administrative waste in health-care where provider organizations are understaffed and don’t have time to even follow up on a claim when it does get denied, we’re bringing software to bear that helps to automate that experience,” Hawkins said.

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AWS and General Catalyst partner to speed up development of health-care AI tools

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AWS and General Catalyst partner to speed up development of health-care AI tools

Attendees walk through an expo hall at AWS re:Invent, a conference hosted by Amazon Web Services, at the Venetian in Las Vegas on Nov. 28, 2023.

Noah Berger | Getty Images Entertainment | Getty Images

Amazon Web Services and venture capital firm General Catalyst on Monday announced a new multi-year partnership in their latest push to carve out a piece of health-care’s growing artificial intelligence market. 

Through the collaboration, General Catalyst portfolio companies will use AWS’ services to build and roll out AI tools for health systems more quickly. Aidoc, which applies AI to medical imaging, and Commure, which automates provider workflows with AI, will be the first two companies to participate.

No financial terms were disclosed in the announcement.

“Without a strong partner like Amazon and AWS to stand alongside them, to co-develop and support these companies … it’s not going to move as fast as we hope,” Chris Bischoff, head of global health-care investing at General Catalyst, told CNBC in an interview. 

Health systems are strained in the U.S., with staff burnout, growing labor shortages and razor-thin margins. These challenges often seem enticing for enterprising tech startups to tackle, especially as the multi-trillion dollar health-care industry dangles the prospect of large financial returns. 

Hospitals operate in a complex, technology-weary and highly-regulated sector that can be difficult for startups to break into. General Catalyst is hoping to help its companies fast-track the development and go-to-market process by leveraging resources like computing power from AWS.  

Read more CNBC reporting on AI

General Catalyst is no stranger to taking big swings in health-care. 

The firm has closed more than 60 digital health deals since 2020, behind only Gaingels and Alumni Ventures, according to a December report from PitchBook. Last January, General Catalyst shocked the industry by announcing that its new business, the Health Assurance Transformation Company, planned to acquire an Ohio-based health system – an unprecedented move in venture capital. 

General Catalyst’s “deep understanding” of health systems’ financial and operating realities made it an attractive partner for AWS, Dan Sheeran, AWS’ general manager of Healthcare & Life Science, told CNBC. Sheeran and Bischoff began outlining the collaboration between the two groups after meeting in London around nine months ago.   

AWS also has an established presence in the health-care sector. The company offers more health- and life-sciences-specific services than any other cloud provider, according to a release, and it inked other high-profile AI partnerships with GE HealthCare, Philips and others last year. 

The partnership between General Catalyst and AWS will stretch over several years, but new tools from Aidoc and Commure are coming in 2025. Aidoc is exploring how it can use the cloud to tap data modalities across pathology, cardiology, genomics and other molecular information, for instance. 

Aidoc and Commure were selected to kick off the collaboration because they have both established a product-market fit, are operational and are focused on issues that are a high priority for AWS customers.

“GC has spent a lot of time thinking about how health systems can transform themselves, and we recognize that it’s not going to be through 1,000 companies, and we need solutions that are really enterprise grade,” Bischoff said. “Amazon shares the same vision, so we are starting with these two.”  

Though the partnership between General Catalyst and AWS is still in its early days, the organizations said they believe it will help serve as a way to meet the market’s growing demand for new solutions. 

“Health system leaders who want to realize the benefits of AI now have an easier way to accomplish that,” Sheeran said.

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