An elderly man from Alaska has become the first person to die after contracting Alaskapox – a recently discovered viral disease.
But how dangerous isAlaskapox, how many people have caught it and what are the symptoms? Here’s everything you need to know.
What is it?
Alaskapox, or AKPV, is a double-stranded DNA virus with officials saying it appears to be zoonotic, primarily circulating across Alaska’s state mammals with occasional transmission to humans.
It’s a type of bug known as an orthopoxvirus. The most well-known variation of this type of virus is smallpox. There’s also camelpox, cowpox, horsepox and mpox – formerly known as monkeypox.
When was it discovered and how many people have had it?
It was discovered in 2015 in a woman who lived near Fairbanks, Alaska, hence the name Alaskapox. She was diagnosed after she began suffering from a localised rash and swollen lymph nodes.
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It has mainly been found in small mammals, including red-backed voles and shrews, but health officials say household pets may also carry the virus.
Seven people, all in Alaska, have been infected with it in the last nine years.
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The latest known case was the elderly man from Kenai Peninsula, to the south of the state, who health officials say was undergoing treatment in hospital when he died in late January.
Image: The man was from the Kenai Peninsula, in the south of Alaska. Pic: iStock
How does it spread?
Officials believe it’s through contact with infected animals.
There has been no documented case of it spreading from one person to another. But other viruses in the same family can spread when one person comes in contact with another person’s lesions, so Alaska health officials are advising anyone with an Alaskapox lesion to cover it with a bandage.
Officials said it was “unclear” how the man who died was exposed to the virus – although he had reported caring for a stray cat at his home which had scratched him, possibly causing the transmission.
What are the symptoms?
Symptoms have included one or more bumps or pustules on the skin, as well as joint or muscle pain and swollen lymph nodes.
Nearly all patients had mild illnesses that resolved on their own after a few weeks without the need for treatment.
Image: An Alaskapox lesion photographed over a four-week period. Pic: AP/Alaska Department of Health
The man who died in January was being treated for cancer and had a suppressed immune system because of the drugs, which the Alaskan health department said likely contributed to the severity of his illness.
He spotted a red bump in his armpit in September and was given antibiotics, however his symptoms worsened as he experienced fatigue and increased pain in the area and shoulder.
After his right arm’s range of motion was impacted, the man was transferred to a hospital in Anchorage where he reported further symptoms including pox-like lesions, the case report said.
An “extensive battery” of tests were performed and showed a positive result for cowpox.
While his condition improved one week into the therapy, he would soon suffer from delayed wound healing, respiratory and kidney failure, resulting in his death.
The man began to improve about a week after treatment with intravenous medications but died in late January after experiencing kidney failure and other systemic declines, according to officials.
Could this spread beyond Alaska?
Officials have yet to comment on the possibility of the virus spreading to other regions.
As we said before, all seven cases detected so far have been in Alaska, and six of those have occurred in people living in the same borough: Fairbanks North Star Borough (FNSB).
The latest case, however, was found in the elderly man living in the Kenai Peninsula Borough, which is 370 miles from FNSB, according to Google Maps.
A statement from the Alaska Division of Public Health explains how prevalent the virus could be throughout the US state: “While animal trapping studies have confirmed the presence of the virus in small mammals in FNSB, it is likely that the virus is present more broadly in Alaska’s small mammals and that more infections in humans have occurred but were not identified.
“More animal testing is occurring to better understand the distribution of the virus in animal populations throughout Alaska.”
How to protect yourself and pets once the virus is caught
Officials say the best ways to keep pets and family members safe is to keep a safe distance and wash your hands after being outdoors. It also advises avoiding keeping wildlife as pets.
Any lesions that are found should be covered, kept dry and not touched, they add.
US President Donald Trump says he has yet to decide whether the US will join Israel militarily in its campaign against Iran.
Asked whether the US was getting closer to striking Iran’s nuclear facilities, Mr Trump said: “I may do it. I may not do it.”
Speaking outside the White House on Wednesday, he added: “Nobody knows what I’m going to do…Iran’s got a lot of trouble, and they want to negotiate.
“And I said, ‘why didn’t you negotiate with me before all this death and destruction?'”
Mr Trump said Iran had reached out to Washington, a claim Tehran denied, with Iran’s mission to the UN responding: “No Iranian official has ever asked to grovel at the gates of the White House.”
Iran’s supreme leader, Ayatollah Ali Khamenei said Iran would not surrender and warned “any US military intervention will undoubtedly cause irreparable damage” to US-Iranian relations.
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The families caught up in Iran-Israel attacks
Strikes continue
Hundreds have reportedly died since Iran and Israel began exchanging strikes last Friday, when Israel launched an air assault after saying it had concluded Iran was on the verge of developing a nuclear weapon, a claim Tehran denies.
Israel launched three waves of aerial attacks on Iran in the last 24 hours, military spokesman Brigadier General Effie Defrin has said.
Israel deployed dozens of warplanes to strike over 60 targets in Tehran and western Iran, including missile launchers and missile-production sites, he said.
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Can Iran’s leadership be toppled?
“The aim of the operation is to eliminate the existential threat to the State of Israel, significantly damage Iran’s nuclear programme in all its components, and severely impact its missile array,” he said.
Early on Thursday Israel issued an evacuation warning to residents of the Iranian Arak and Khandab regions where Iran has heavy water reactor facilities. Heavy water is important in controlling chain reactions in the production of weapons grade plutonium.
Meanwhile Iran says it has arrested 18 people it describes as “enemy agents” who it says were building drones for the Israelis in the northern city of Mashhad.
Iran also launched small barrages of missiles at Israel on Wednesday with no reports of casualties. Israel has now eased some restrictions for its civilians.
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The US is working to evacuate its citizens from Israel by arranging flights and cruise ship departures, the US ambassador to the country has said.
In the UK, Sir Keir Starmer chaired a COBRA emergency meeting on the situation in the Middle East, with a Downing Street spokesperson saying: “Ministers were updated on efforts to support British nationals in region and protect regional security, as well as ongoing diplomatic efforts”.
A senior US senator who supports Donald Trump has told Sky News why he believes the US would be right to intervene in Iran.
Senator Ted Cruz, a Republican from Texas who ran against Mr Trump in 2016 but now backs him, told US correspondent David Blevins that Iran is an “acute threat to the national security of the US”.
He went on to claim that because “Iran is also building ICBMs (intercontinental ballistc missiles)” and “You don’t need an ICBM to go to Israel”, it indicated Iran’s intention “to take a nuclear weapon to the United States to murder Americans”.
“Nobody is talking about invading Iran,” Mr Cruz added. “We’re not going to see boots on the ground.”
It comes after the US president said he “may do it, I may not do it” when asked if he would launch a strike against Iranian nuclear facilities.
So far, Israel has been attacking Iran alone since it ramped up its military action last Friday, launching strikes against what it says are Tehran’s facilities for developing a nuclear weapon and also destroying its air defences.
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Iran has always denied seeking the ability to make a nuclear weapon from its uranium enrichment programme.
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Blevins’s fellow US correspondent Mark Stone says that while figures like Mr Cruz back military action, “a whole host of other figures are saying ‘do not do it'”.
“The social media space is absolutely full of MAGA [Make America Great Again] figures from the right… saying ‘we absolutely must not go into Iran’.”
If the US were to decide to take military action against Iran, it could have implications for the UK, as America may ask to station refuelling aircraft at a British base in Cyprus and B-2 bombers, which could carry the bunker buster bombs required to attack Iran’s Fordow nuclear enrichment facility, could launch from the British base of Diego Garcia.
Mr Cruz told Sky News that while many of Mr Trump’s support base did not want to see the US involve itself in another war, “the overwhelming majority of Americans, nearly 80%, support President Trump, and support President Trump defending us against an Iranian nuclear weapon.”
America is deploying more fighter planes to the Middle East in a “demonstration of force” as tensions escalate and speculation about a possible US strike on Iran continues.
Pictures and flight tracking data show F-35 jets and tanker aircraft being moved towards the region, as well as the tasking of an aircraft carrier, providing options in case President Donald Trump decides to intervene in the conflict.
But one particular aircraft that has not been seen just yet – the B-2 stealth bomber – could reveal the most about America’s intentions towards Iran…
Why is America moving more aircraft to the Middle East?
“It’s giving them options,” says military analyst Michael Clarke. “They have got four types of aircraft – including fighters, interceptors and fighter-bombers – all in the right region.”
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Clarke: What could US involvement look like as Iran attacks ease
The new arrivals can be spread around several existing military bases that the US has in the region in Bahrain, Qatar, UAE, Kuwait and Saudi Arabia.
“More is better and also it’s a demonstration of force,” Prof Clarke added. “There’s a political element behind it, to show the Iranians what they can do, but also to other allies.
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“The Americans want to be taken seriously in all of this.”
Image: A Boeing KC-46A Pegasus, primarily used for aerial refueling, is seen on tracking in the eastern Mediterranean. Pic: Flightradar24
Analysis: What aircraft have moved to the region?
Sky News analysis of flight-tracking data shows more than 30 US military planes have been active over parts of Europe and the Mediterranean Sea over the past three days.
These include planes used for reconnaissance, refuelling in mid-air as well as carrying cargo.
Image: Map of US military bases in the Middle East
An air-traffic control recording from the US suggests F-22 Raptors are being sent across the Atlantic. Two refuelling tankers are visible on flight tracking data leaving the US east coast, likely escorting the stealth fighter jets.
In images taken by photographer Glenn Lockett in Suffolk, three US air tankers were seen flying over England, each accompanied by four F-35 jets.
F-35s are one of the most advanced warplanes in the world, known for their ability to evade enemy radar.
Image: A US air tanker seen flying over England, accompanied by F-35 jets. Credit: Instagram/g.lockaviation
Flight tracking data shows that the tankers travelled to the Mediterranean and then returned to the UK.
Most of the US military planes tracked by Sky News regularly turn off their locations and final destinations, according to the data from Flightradar24.
Some of the planes moved from the US to Europe, while others appeared to move closer to the Middle East. At least five of the US military aircraft landed at Chania Airport on the Greek island of Crete.
An air-traffic control recording from the US also suggests F-22 Raptors are being sent across the Atlantic. Two refuelling tankers are visible on flight tracking data leaving the US east coast, likely escorting the stealth fighter jets.
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US defence secretary Pete Hegseth stressed that the deployment of more aircraft was defensive in nature, as Washington looks to safeguard its forces in the region.
Fighter aircraft have been used to shoot down drones and projectiles in the past.
America already has a substantial force in the Middle East, with nearly 40,000 troops as well as air defence systems, aircraft and warships.
But as the conflict between Israel and Iran carries on – and President Trump continues to make threats against Tehran – it’s possible that multiple options could be on the table for intervention.
B-2 bombers – the ones to watch?
Asked what he’s looking out for as speculation about whether the US will intervene directly continues, Prof Clarke pointed to one particular aircraft that hasn’t been seen moving towards the region yet: The B-2 stealth bomber.
Known for its iconic triangle shape and ability to penetrate deep air defences undetected, the B-2 has lesser-known capability that could be crucial for any action over Iran: it can carry ‘bunker buster’ bombs.
So far Israel has not been able to damage Iran’s secretive Fordow uranium enrichment plant, which is buried deep beneath a mountain.
Image: A B-2 stealth bomber flies over Washington DC during a 4 July celebration. File pic: AP
Any movement of B-2 bombers to the joint UK-US base on Diego Garcia in the Indian Ocean could “indicate the likelihood that the Americans are going to use bunker busters in Iran,” Prof Clarke says.