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More widespread use of powerful weight-loss drugs like Ozempic in the U.S. could boost the economy in the coming years, according to Goldman Sachs strategists. 

The bank estimates that weight-loss drugs, called GLP-1 agonists, could increase the nation’s gross domestic product by an extra 1% over the next decade, the equivalent of about $360 billion per year. 

The thinking behind Goldman’s forecast is that poor health is a burden to economic growth, largely because it limits the number of available workers and hours worked due to increased missed days at work as a result of “sickness and disability, early deaths and informal caregiving.”

In fact, Goldman said that GDP in the U.S. would potentially be more than 10% higher if poor health outcomes did not affect the labor supply.

“The main reason we see meaningful upside from healthcare innovation is that poor health imposes significant economic costs. There are several channels through which poor health weighs on economic activity that could diminish if health outcomes improve,” the analysts, led by Jan Hatzius, wrote.

Drug companies are vying to join what has largely been a two-horse race to make obesity drugs.

Novo Nordisk the maker of Ozempic and Wegovy and Eli Lilly, the producer of Mounjaro, skyrocketed in popularity last year amid runaway demand for the drugs, which are taken by A-listers including Oprah Winfrey and Tesla CEO Elon Musk.

Similar drugs could enter the market depending on clinical trials. 

The market is expected to top $100 billion by 2030, according to one estimate from JPMorgan.

Goldman projects that anywhere between 10 million to 70 million Americans will be taking weight-loss drugs by 2028.

The wide range stems from uncertainty over clinical trials, health insurance and available supply.

“If GLP-1 usage ultimately increases by this amount and results in lower obesity rates, we see scope for significant spillovers to the broader economy,” the analyst note said. “Academic studies find that obese individuals are both less likely to work and less productive when they do.”

The economy would grow by 0.4% in a scenario where there are 30 million users, and 1% if 60 million Americans were taking these types of drugs.

“Historically, health advancements have lowered the number of life years lost to disease and disability by 10% per decade in DM economies, and we estimate that a 10-year step forward in health progress in excess of current trends could raise the level of US GDP by 1%,” Hatzius said.

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Business

Farming: Cost of rural crime in Wales at its highest in more than a decade

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Farming: Cost of rural crime in Wales at its highest in more than a decade

The cost of rural crime in Wales is at its highest in more than a decade, a new report has revealed.

Last year, rural crime cost an estimated £2.8m in Wales, according to insurance provider NFU Mutual.

That’s an 18% increase on the previous year, with Wales the only UK nation to have seen a rise.

For farmers like Caryl Davies, that makes their work harder.

The 21-year-old farms on a beef and sheep farm in Pembrokeshire.

She told Sky News that having the quad bike stolen from her family farm last August had made them feel “really unsafe at home”.

Caryl Davies's farm in Eglwyswrw, Pembrokeshire
Pic: Tomos Evans (no credit needed)
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Caryl Davies farms in North Pembrokeshire

The fact it happened in such a rural area was a “really big shock” for Ms Davies and her family.

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“We’d rely on the bike day in day out, to look after our cows and sheep, and it’s had a really negative impact on us,” she said.

The cost of replacing a bike exactly like theirs would be “close to £10,000”.

“They’re a really expensive piece of kit, but you can’t be without them, especially in these rural areas where we’ve got the mountain and maybe places that aren’t very accessible,” she added.

“The bike is totally crucial for our day-to-day running of the farm.”

Caryl Davies
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Caryl Davies

The incident was caught on camera in the calving shed, but the Davies family have since invested in an enhanced CCTV system. That comes at an additional cost.

“For some farmers, this is spare money that we haven’t really got,” Ms Davies added.

“Farming is hard enough as it is, without people stealing your things and having to spend this extra money on making your home farm safe.”

The total cost of rural crime across the UK has fallen since 2023 – down from £52.8m to £44.1m.

Quad bike and All Terrain Vehicles (ATVs) remained the top target for thieves during the past year, NFU Mutual’s figures show.

James Bourne farms in Pontypool, Torfaen, and claims to have had over 200 sheep stolen from common land adjoining his farm over a four-year period.

The 32-year-old told Sky News that losing sheep from his herd was a “big hit” on his business as well as the young family he is trying to support.

“The way agriculture is at the moment anyway, we’re struggling to make ends meet, and any profit that is in it is obviously being taken from me,” he said.

“So I really need to try and find out and get to the bottom of where they’re going because obviously it’s an ongoing issue.”

James Bourne
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James Bourne

Andrew Chalk, from NFU Mutual, told Sky News that while there had been a “significant drop” across the UK, there were “worrying signs”.

“In Wales, especially, rural crime’s gone up which just shows that organised criminals are looking for ways to target the countryside again and again,” he said.

“What we’ve found increasingly is that organised criminals are targeting certain areas of the countryside, so they’re hitting multiple farms in one night.

“They’re raiding them, they’re moving away to another area and then hitting multiple farms there. So it is hugely concerning.”

Andrew Chalk
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Andrew Chalk

Mr Chalk said NFU Mutual had also heard reports of criminals using drones and other equipment to “look at the lay of the land”.

“What it does show is that organised criminals are always going to find new ways to target rural crime and that’s why we need to be on top of it and to work together to actually disrupt them,” he added.

Police forces in Wales say they are aware of the “significant impact” that rural crimes have on those affected.

A Dyfed-Powys Police spokesperson said the force had acquired new technology to help combat rural crime, including “advanced DNA asset-marking kits” and hopes to “empower farmers with effective tools and advice”.

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The spokesperson acknowledged the difficulty of patrolling the entire police force area, “given the huge area” it has to cover, and thanked rural communities for their “continuing vigilance and for reporting any suspicious activity”.

Temporary Chief Superintendent Jason White, from Gwent Police, said the force would be “increasing resources” within the rural crime team throughout this financial year and urged anyone in a rural area who believes they have been a victim of crime to get in touch.

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US

Suspect in shooting of Minnesota politicians captured after two-day manhunt

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Suspect in shooting of Minnesota politicians captured after two-day manhunt

A man has been taken into custody two days after a US politician and her husband were shot dead in Minnesota, law enforcement officials have said.

Authorities had urged the public not to approach Vance Boelter, 57, who they warned could be armed, and who was reportedly posing as a police officer.

A massive manhunt was launched on Saturday after Melissa Hortman and Mark Hortman were shot dead at their home in Minneapolis in what Minnesota governor Tim Walz called a “politically motivated assassination”.

Police said the same gunman that killed the Hortmans had earlier shot and wounded Democrat senator John Hoffman and his wife, Yvette, at their home nine miles away.

Graphic of Minnesota State Representative Melissa Hortman (L) and Senator John Hoffman. Pic: Facebook / Minnesota Legislature
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Representative Melissa Hortman and Senator John Hoffman. Pic: Facebook/Minnesota Legislature

Boelter was arrested on Sunday evening in a rural area in Sibley County, southwest of Minneapolis.

He faces two counts of second-degree murder and two counts of attempted second-degree murder in the deaths of the Hortmans and the wounding of Hoffman and his wife.

The FBI released this image of Vance Boelter posing as a police officer. Pic: FBI.
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The FBI released this image of Vance Boelter posing as a police officer. Pic: FBI.

Police said they responded to gunfire reports at the Hoffmans’ Champlin home shortly after 2am on Saturday and found them with multiple gunshot wounds.

They then checked on the Hortmans’ home, in the nearby Brooklyn Park suburb, and saw what appeared to be a police car and a man dressed as an officer leaving the front door.

“The individual immediately fired upon the officers, who exchanged gunfire, and the suspect retreated back into the home” and escaped on foot, said Brooklyn Park police chief Mark Bruley.

Authorities believe Boelter wore a mask as he posed as a police officer, and also used a vehicle resembling a squad car.

Several AK-style firearms and a list of about 70 names, which included politicians and abortion rights activists, were allegedly found inside the vehicle.

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Governor calls it ‘targeted political violence’

‘We are both incredibly lucky to be alive’

Senator Hoffman was shot nine times and is having multiple surgeries, according to a text message shared on Instagram by fellow senator Amy Klobuchar on Sunday.

The text from Yvette Hoffman added: “I took 8 and we are both incredibly lucky to be alive.”

She said her husband “is closer every hour to being out of the woods”.

Read more:
Neighbours of murdered US politician stunned

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Neighbours of killed US politician stunned

Records show Boelter – a father of five – is a former political appointee who served on the same state workforce development board as Mr Hoffman.

However, it’s unclear to what extent they knew each other, if at all.

Mr Hoffman, 60, was first elected in 2012 and runs a consulting firm called Hoffman Strategic Advisors.

Melissa Hortman, a 55-year-old mother of two, was first elected in 2004 and was the top house Democratic leader in the state legislature.

She also served as speaker of the Minnesota House of Representatives.

Melissa Hortman. Pic: Instagram.
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The motive behind Melissa Hortman’s killing remains unclear. Pic: Instagram.

Mrs Hortman used her position to champion protections around abortion rights, including laws to cement Minnesota’s status as a safe refuge for people from restrictive states, who travel there for an abortion.

Her work also sought to introduce protections for services that provide abortions.

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UK

Career spy Blaise Metreweli to become first woman to head MI6

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Career spy Blaise Metreweli to become first woman to head MI6

Career spy Blaise Metreweli will become the first woman to head MI6 in a “historic appointment”, the prime minister has announced.

She will take over from Sir Richard Moore as the 18th Chief, also known as “C”, when he steps down in the autumn.

“The historic appointment of Blaise Metreweli comes at a time when the work of our intelligence services has never been more vital,” Sir Keir Starmer said in a statement released on Sunday night.

“The United Kingdom is facing threats on an unprecedented scale – be it aggressors who send their spy ships to our waters or hackers whose sophisticated cyber plots seek to disrupt our public services.”

Of the other main spy agencies, GCHQ is also under female command for the first time.

Anne Keast-Butler took on the role in 2023, while MI5 has previously twice been led by a woman.

Until now, a female spy chief had only headed MI6 – also known as the Secret Intelligence Service (SIS) – in the James Bond movies.

A motorboat passes by the MI6 building in Vauxhall, London. Pic: Reuters
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Blaise Metreweli is the first woman to be named head of MI6. Pic: Reuters

Dame Judi Dench held the fictional role – called “M” in the films instead of “C” – between 1995 and 2015.

Ms Metreweli currently serves as “Q”, one of four director generals inside MI6.

The position – also made famous by the James Bond films, with the fictional “Q” producing an array of spy gadgets – means she is responsible for technology and innovation.

Ms Metreweli, a Cambridge graduate, joined MI6 in 1999.

Unlike the outgoing chief, who spent some of his service as a regular diplomat in the foreign office, including as ambassador to Turkey, she has spent her entire career as an intelligence officer.

Much of that time was dedicated to operational roles in the Middle East and Europe.

Ms Metreweli, who is highly regarded by colleagues, also worked as a director at MI5.

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In a statement, she said she was “proud and honoured to be asked to lead my service”.

“MI6 plays a vital role – with MI5 and GCHQ – in keeping the British people safe and promoting UK interests overseas,” she said.

“I look forward to continuing that work alongside the brave officers and agents of MI6 and our many international partners.”

Sir Richard said: “Blaise is a highly accomplished intelligence officer and leader, and one of our foremost thinkers on technology. I am excited to welcome her as the first female head of MI6.”

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