US company hoping to bring back the dodo and the mammoth – but here’s why it won’t be like Jurassic Park
The idea of scientists bringing pre-historic creatures back to life with some clever DNA trickery might sound familiar to fans of the 1993 Hollywood blockbuster Jurassic Park.
But for Colossal Biosciences – a company that hopes to reintroduce extinct species such as the dodo and the mammoth – it is more than just a film script.
It’s a reality – and one that could be just years away.
“We’ve got all the technology we need,” says Ben Lamm, chief executive of the firm, based in Dallas, Texas.
“It is just a focus of time and funding. But we are 100% confident [we can bring back] the Tasmanian tiger, the dodo, and the mammoth.”
The science behind the project is simple: Work out the genes that make an extinct animal what it is, and then replicate those genes using the DNA of a close existing relative.
“It’s almost reverse Jurassic Park,” says Mr Lamm, speaking to Sky News.
“In the film, they were filling in the holes in the dinosaur DNA with frog DNA.
“We are leveraging artificial intelligence and other tools to identify the core genes that make a mammoth a mammoth and then engineering them into elephant genomes.”
Ben Lamm, founder and chief executive of Colossal Biosciences. Pic: Colossal
That is the technical part.
But there are some other practical hurdles for Colossal to overcome, namely how, once you have mammoth cells, do you birth a real-life mammoth?
The answer, according to Colossal, is in the womb of an Asian elephant.
But it is a process that could take nearly two years, even after they have worked out how to do it.
“[Each of the] different projects [the mammoth, dodo, and Tasmanian tiger] have different challenges – the mammoth is really around gestation – which is around 22 months,” says Mr Lamm.
“The dodo gestation is pretty great – we are using surrogate chickens. The hardest part is cultivating the primordial germ cells.”
Colossal plans to create cells of extinct animals by genetically engineering the cells of their closest living relatives. Pic: Colossal
Pic: Colossal
‘Feeling good about 2028’
So after around 4,000 years of extinction, when could we see the return of the mighty mammoth – a creature that fell victim to human hunting and the changing conditions brought about by the end of the last Ice Age.
“We are well into the editing phase,” says Mr Lamm.
“We don’t have mammoths yet, but we still feel very good about 2028.”
Away from the lab, led by Eriona Hysolli, Colossal’s head of biological sciences, there are other issues to overcome – including where the newly returned species will live once they are born.
Eriona Hysolli, head of biological sciences at Colossal Biosciences. Pic: Colossal
Mr Lamm says the company is already working with local governments, conservation groups, indigenous people groups, private land lowers, and the public at large, to prepare for the animals to be returned to their natural habitat.
“Our ultimate goal is to put all the animals we make back into the wild,” he says.
‘New tools in the fight’ to protect nature
Colossal says the work is not just about rewilding animals previously lost to the world.
The company is currently working with Dr Paul Ling at Baylor College of Medicine in Houston, Texas, to create a vaccine to eradicate the deadly EEHV virus – which kills around 20% of baby elephants each year.
It is also working closely with the University of Alaska and the University of Stockholm on radiocarbon dating of American mammoths as well as sequencing their genome – the largest study of its type ever undertaken.
Read more:
Colossal Biosciences announces project to bring back the dodo
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Mr Lamm also hopes that, through Colossal’s research, the company can tackle issues facing the world today, including a drop in biodiversity.
“I think we have a duty to this planet that we’ve been given – we are tending towards a loss of up to 50% biodiversity if we don’t do anything,” he says.
“Modern conservation is great, but we need new tools in the fight.
“Work on de-extinction goes hand-in-hand with species preservation, and if Colossal makes a couple of technologies, then maybe it will provide those tools.”
‘Jurassic Park helps people understand our work’
As for the Jurassic Park comparisons, well, there is one small issue, according to Mr Lamm.
In the Steven Spielberg-directed epic, the scientists use DNA embedded in fossilised mosquitoes in amber combined with frog DNA to bring dinosaurs back to life.
The scientists in Jurassic Park combined dinosaur DNA embedded in fossilised mosquitoes. Pic: PA
“Amber is not a good holder of DNA,” Mr Lamm says.
“But it’s a very entertaining movie and I think Jurassic Park made a lot of people interested in science. I saw it when I was younger and I was like: ‘Wow genetics is cool’.
“It did a lot to explain to the masses that genetic engineering is a thing and something that can be used in powerful ways, and I do think more people understand Colossal because of that.”
The company is also working on a film of its own, and, luckily for everyone, it’s not a dystopian thriller like Jurassic Park.
It has teamed up with award-winning director James Reed, a specialist in nature films, to document its “de-extinction” work.
“It’s really exciting. When you are doing anything bold, it is important to communicate and be transparent, and there’s nothing more transparent than having cameras around all the time,” says Mr Lamm.
The King has written to former US president Joe Biden after he was diagnosed with an aggressive form of prostate cancer, Buckingham Palace said
The monarch, who is undergoing his own treatment for an undisclosed cancer, hosted the 82-year-old for tea and talks at Windsor in July 2023.
Mr Biden was diagnosed on Friday, with tests revealing the cancer had spread to his bones.
The former president posted an image of himself and his wife Jill on X on Monday and wrote: “Cancer touches us all. Like so many of you, Jill and I have learned that we are strongest in the broken places. Thank you for lifting us up with love and support.”
The King and Joe Biden at Windsor Castle in July 2023. Pic: Reuters
The King’s letter comes after British Prime Minister Sir Keir Starmer said he was “very sorry to hear President Biden has prostate cancer”.
“All the very best to Joe, his wife Jill and their family, and wishing the President swift and successful treatment,” he added.
Meanwhile US President Donald Trump said he was “saddened” by the news, adding: “We extend our warmest and best wishes to Jill and the family, and we wish Joe a fast and successful recovery.”
Former US president Barack Obama said: “Michelle and I are thinking of the entire Biden family.
“Nobody has done more to find breakthrough treatments for cancer in all its forms than Joe, and I am certain he will fight this challenge with his trademark resolve and grace. We pray for a fast and full recovery.”
Read more: Biden diagnosed with ‘aggressive’ form of prostate cancer
Barack Obama (right) with Joe Biden at a campaign event in 2022. File pic: Reuters
After a poor debate performance against Mr Trump and amid escalating concerns around his age and fitness to serve, Mr Biden withdrew from the 2024 presidential election race and endorsed his vice president Kamala Harris.
Ms Harris wrote on X after his diagnosis: “We are keeping him, Dr. Biden, and their entire family in our hearts and prayers during this time.
“Joe is a fighter – and I know he will face this challenge with the same strength, resilience, and optimism that have always defined his life and leadership. We are hopeful for a full and speedy recovery.”
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Mr Biden’s diagnosis: What we know
Former US president Bill Clinton wrote on social media: “My friend Joe Biden’s always been a fighter. Hillary and I are rooting for him and are keeping him, Jill, and the entire family in our thoughts.”
Hillary Clinton, who unsuccessfully ran for president in 2016, said she was “thinking of the Bidens as they take on cancer, a disease they’ve done so much to try to spare other families from”.
Speaker of the US House of Representatives Mike Johnson said it was “sad news” and his family “will be joining the countless others who are praying” for Mr Biden.
Read more from Sky News:
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Former House speaker Nancy Pelosi described Mr Biden as a “great American patriot” and said she was “praying for him to have strength and a swift recovery”.
Mr Trump’s secretary of state, Marco Rubio, wrote on social media that he and his wife were “united in prayer for the Biden Family during this difficult time”.
Politicians have sent messages of support to Joe Biden, who has been diagnosed with prostate cancer.
The 82-year-old, who is the oldest person to ever serve as US president, was described as a “fighter” with people wishing him a “fast and full recovery”.
US President Donald Trump said he was “saddened” by the news, adding: “We extend our warmest and best wishes to Jill and the family, and we wish Joe a fast and successful recovery.”
Former US president Barack Obama said: “Michelle and I are thinking of the entire Biden family.
“Nobody has done more to find breakthrough treatments for cancer in all its forms than Joe, and I am certain he will fight this challenge with his trademark resolve and grace. We pray for a fast and full recovery.”
Read more: Biden diagnosed with ‘aggressive’ form of prostate cancer
Barack Obama (right) with Joe Biden at a campaign event in 2022. File pic: Reuters
British Prime Minister Sir Keir Starmer said he was “very sorry to hear President Biden has prostate cancer”.
“All the very best to Joe, his wife Jill and their family, and wishing the President swift and successful treatment,” he added.
After a poor debate performance against Mr Trump and amid escalating concerns for his health, Mr Biden withdrew from the 2024 election and endorsed his vice president Kamala Harris.
Ms Harris wrote on X: “We are keeping him, Dr. Biden, and their entire family in our hearts and prayers during this time.
“Joe is a fighter – and I know he will face this challenge with the same strength, resilience, and optimism that have always defined his life and leadership. We are hopeful for a full and speedy recovery.”
Please use Chrome browser for a more accessible video player
Mr Biden’s diagnosis: What we know
Former US president Bill Clinton wrote on social media: “My friend Joe Biden’s always been a fighter. Hillary and I are rooting for him and are keeping him, Jill, and the entire family in our thoughts.”
Hillary Clinton, who unsuccessfully ran for president in 2016, said she was “thinking of the Bidens as they take on cancer, a disease they’ve done so much to try to spare other families from”.
Speaker of the US House Of Representatives Mike Johnson said it was “sad news” and his family “will be joining the countless others who are praying” for Mr Biden.
Read more from Sky News:
UK and EU sign reset deal – live updates
Gary Lineker to leave BBC next week
Listen to The World with Richard Engel and Yalda Hakim every Wednesday
Former House speaker Nancy Pelosi described Mr Biden as a “great American patriot” and said she was “praying for him to have strength and a swift recovery”.
Mr Trump’s secretary of state, Marco Rubio, wrote on social media he and his wife were “united in prayer for the Biden Family during this difficult time”.
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