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An early-stage clinical trial has come back with promising results for a chlamydia vaccine, researchers have said.

There is currently no jab to protect against the disease, which is one of the most common sexually transmitted infections (STIs) in the UK.

Almost 200,000 cases were identified in England alone in 2022, a nearly 25% rise from the year before, according to latest NHS figures.

Chlamydia is a common cause of infertility in women. It can cause pelvic inflammatory disease, which can lead to scar tissue which makes it harder to get pregnant if left untreated.

The bacteria can also cause an eye infection that is responsible for vision loss in 1.9 million people worldwide, according to the Centers for Disease Control and Prevention in the US.

An early clinical trial of the experimental vaccine, led by researchers in the UK and Denmark, found it was safe and induced an immune response, according to findings published in The Lancet Infectious Diseases journal.

More than 150 people took part in the study between 2020 and 2022 at the National Institute for Health Research in London.

Participants were equally split between healthy men and women with an average age of 26. None of them had chlamydia.

The researchers tested several different dosages of the vaccine, and participants got either the jab or a placebo on three separate days over a period of almost four months.

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Although the vaccine induced an immune response, Dr Hilary Reno, medical director of the St Louis County Sexual Health Clinic, said questions remained about its effectiveness.

She said: “Does it confer the ability to hold off infection with chlamydia? If you do have an infection, does it mean you’re more likely to have an asymptomatic infection?

“We don’t know that and that’s what the next phase of studies would be.”

The researchers are now planning to launch a larger, “phase two” trial that would look at the vaccine’s effectiveness.

The hope is that one day the jab will be able to prevent both infections in the reproductive system, as well as in the eyes, said Jes Dietrich, a senior scientist at the Statens Serum Institute in Denmark and a lead author of the study.

In addition to a shot in the arm, participants in the study also received a vaccine in the form of an eye drop.

“I was very pleasantly surprised because it’s really difficult to induce immunity in the eye,” Dr Dietrich said.

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Measles cases surge across the country

David Harvey, executive director of the National Coalition of STD Directors in the US, said the vaccine was “desperately needed”.

One of the other most common STIs is the Human Papillomavirus (HPV), although most people with the virus have no symptoms.

Some strains are associated with cervical cancer and the UK has been offering all secondary school girls an HPV vaccine since 2008.

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Algerian sex offender mistakenly released from prison reacts angrily as he’s arrested

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Algerian sex offender mistakenly released from prison reacts angrily as he's arrested

A foreign sex offender freed in error from Wandsworth prison has been arrested – as Sky News filmed the moment he was detained.

Brahim Kaddour-Cherif, a 24-year-old Algerian national, was mistakenly released from HMP Wandsworth in south London on 29 October.

Sky News approached Kaddour-Cherif moments before his arrest in Finsbury Park, north London, at 11.30am, but he claimed to be someone else.

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He was then approached by officers next to a police van and arrested.

One of the officers said Kaddour-Cherif had been identified as the missing prisoner because he had a “distinctive wonky nose”.

Sky News witnessed Brahim Kaddour-Cherif's arrest
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Sky News witnessed Brahim Kaddour-Cherif’s arrest

Officers held his arrest picture next to Kaddour-Cherif's head to confirm his identity
Image:
Officers held his arrest picture next to Kaddour-Cherif’s head to confirm his identity

In the footage, the Algerian was shown shouting to people standing nearby in the street.

An officer then held up a photo of Kaddour-Cherif on a phone, comparing the image to the man arrested.

When officers asked him whether he knew why he was being arrested, Kaddour-Cherif replied: “I don’t know.”

Kaddour-Cherif, who was wearing a grey hoodie, black beanie and black backpack, said the mix-up at the prison was the fault of the authorities who released him.

“It’s not my f***ing fault”, Kaddour-Cherif shouted.

Kaddour-Cherif shouted at bystanders as officers arrested him
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Kaddour-Cherif shouted at bystanders as officers arrested him

Kaddour-Cherif claimed to be someone else when he was arrested
Image:
Kaddour-Cherif claimed to be someone else when he was arrested

The Prison Service informed the Metropolitan Police about the error six days later – and a huge manhunt for him was launched.

It is not yet clear why it was nearly a week between the release at HMP Wandsworth and the police being informed that an offender was at large.

“At 11.23am on Friday, 7 November, a call was received from a member of the public reporting a sighting of a man they believed to be Brahim Kaddour-Cherif in the vicinity of Capital City College on Blackstock Road in Islington,” a Met Police spokesperson said.

“Officers responded immediately and at 11.30am detained a man matching Cherif’s description. His identity was confirmed and he was arrested for being unlawfully at large.

“He was also arrested on suspicion of assaulting an emergency worker in relation to a previous unrelated incident. He has been taken into police custody. The Prison Service has been informed.”

Kaddour-Cherif shouted it was 'not my f***ing fault' that he was mistakenly released
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Kaddour-Cherif shouted it was ‘not my f***ing fault’ that he was mistakenly released

Kaddour-Cherif is a registered sex offender who was convicted of indecent exposure in November last year, following an incident in March.

At the time, he was given a community order and placed on the sex offenders register for five years.

He was then subsequently jailed for possessing a knife in June.

He was wrongly freed from Wandsworth prison. Pic: Met Police
Image:
He was wrongly freed from Wandsworth prison. Pic: Met Police

Kaddour-Cherif came to the UK legally and is not an asylum seeker, but it is understood he overstayed his visit visa and deportation proceedings had been started.

He was accidentally freed five days after the wrongful release of convicted sex offender Hadush Kebatu. Both Kaddour-Cherif and Kebatu were arrested in Finsbury Park.

A third man, fraudster William Smith, 35, was mistakenly released from HMP Wandsworth on 3 November, but turned himself in on Thursday.

After Kaddour-Cherif’s arrest, Justice Secretary David Lammy admitted there was a “mountain to climb” to tackle the crisis in the prison system.

“We inherited a prison system in crisis and I’m appalled at the rate of releases in error this is causing,” he said.

“I’m determined to grip this problem, but there is a mountain to climb which cannot be done overnight.

“That is why I have ordered new tough release checks, commissioned an independent investigation into systemic failures, and begun overhauling archaic paper-based systems still used in some prisons.”

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Woman who claimed to be Madeleine McCann found guilty of harassing missing toddler’s parents

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Woman who claimed to be Madeleine McCann found guilty of harassing missing toddler's parents

A young woman who claimed to be Madeleine McCann has been convicted of harassing the missing toddler’s family.

However, Julia Wandelt, 24, was cleared of stalking the couple.

A Polish national born three years after Madeleine, Wandelt said she suspected she had been abducted and brought up by a couple who were not her real parents.

She was having mental health issues at the time and had been abused by an elderly relative.

The relative looked like an artist’s drawing of a man who was once a suspect in the Madeleine case, which she stumbled across during internet research on missing children.

She went to Los Angeles and told a US TV chat show audience: “I believe I am Madeleine McCann.”

Madeleine was nearly four when she vanished from the family’s rented holiday apartment in Praia da Luz, Portugal, in May 2007.

She had been left sleeping with her younger twin siblings, Sean and Amelia, while her parents dined nearby with friends, making intermittent checks on the children.

Madeleine is the world’s most famous missing child, the subject of three international police investigations that have failed to find any trace of her.

Wandelt claimed to have a blemish in the iris of her right eye, like Madeleine’s, and to resemble aged-progressed images of her.

Madeleine McCann went missing during a family holiday to Portugal in 2007. Pic: PA
Image:
Madeleine McCann went missing during a family holiday to Portugal in 2007. Pic: PA

Over three years, she attracted half a million followers on her Instagram account, iammadeleinemccan, and posted her claims on TikTok.

Police told her she was not Madeleine and ordered her not to approach her family, but she ignored the warning.

The McCanns and their children gave evidence in the trial at Leicester Crown Court, describing the upset Wandelt had caused them.

Her co-defendant, Karen Spragg, 61, from Cardiff, was found not guilty of stalking and harassment.

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Public ‘at risk’ as more inmates sent to open prisons – with another manhunt under way

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Public 'at risk' as more inmates sent to open prisons - with another manhunt under way

Public safety is “at risk” because more inmates are being sent to prisons with minimal security, a serving governor has warned – as details emerge of another manhunt for a foreign national offender.

Mark Drury – speaking in his role as representative for open prison governors at the Prison Governors’ Association – told Sky News open prisons that have had no absconders for “many years” are now “suddenly” experiencing a rise in cases.

It comes after a man who was serving a 21-year sentence for kidnap and grievous bodily harm absconded from an open prison in Sussex last month.

Sky News has learned that Ola Abimbola is a foreign national offender who still hasn’t returned to HMP Ford – and Sussex Police says it is working with partners to find him.

WARNING: Some readers may find the content in this article distressing

Ola Abimbola absconded from an open prison. Pic: Sussex Police
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Ola Abimbola absconded from an open prison. Pic: Sussex Police

For Natalie Queiroz, who was stabbed 24 times by her ex-partner while she was eight months’ pregnant with their child, the warnings could not feel starker.

Natalie sustained injuries to all her major organs and her arms, while the knife only missed her unborn baby by 2mm.

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“Nobody expected either of us to survive,” she told Sky News.

Babur Raja was sentenced to 18 years for attempted murder, but Natalie has recently been told that he’s set to be moved to an open prison four years earlier than planned.

“Any day now, my ex who created this untold horror is about to go to an open prison,” Natalie said.

Open prisons – otherwise known as Category D jails – have minimal security and are traditionally used to house prisoners right at the end of their sentence, to prepare them for integrating back into society.

With overcrowding in higher security jails, policy changes mean more prisoners are eligible for a transfer to open conditions earlier on in their sentence.

Natalie Queiroz was stabbed 24 times by her ex-partner
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Natalie Queiroz was stabbed 24 times by her ex-partner

“It doesn’t feel right, it’s terrifying, and it also doesn’t feel like justice,” Natalie said, wiping away tears at points.

Previously, rules stated a transfer to open prison could only take place within three years of their eligibility for parole – but no earlier than five years before their automatic release date.

The five-year component was dropped in March last year under the previous government, but the parole eligibility element was extended to five years in April 2025.

Raja, who is due for release in 2034, has parole eligibility 12 years into his sentence, which is 2028.

Under the rule change, this eligibility for open prison is set for this year – but under the new rules it could have been 2023, which is within five years of his parole date.

Another change, introduced in the spring, means certain offenders can be assumed suitable for open prisons three years early – extended from two years.

Natalie says her ex-partner Babur Raja caused 'untold horror'
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Natalie says her ex-partner Babur Raja caused ‘untold horror’

Natalie has been campaigning to prevent violent offenders and domestic abuse perpetrators from being eligible to transfer to an open prison early.

She’s had meetings with ministers and raised both her case and others.

“They actually said – he is dangerous,” she told Sky News.

“I said to [the minister]: ‘How can you make a risk assessment for someone like that?’

“And they went: ‘If we’re honest, we can’t’.”

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What’s wrong with our prisons?

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The government told Sky News that Raja’s crimes were “horrific” and that their “thoughts remain with the victim”.

They also insist that the “small number of offenders eligible for moves to open prison face a strict, thorough risk assessment” – while anyone breaking the rules “can be immediately returned”.

Mark Drury, a representative of the Prison Governors' Association
Image:
Mark Drury, a representative of the Prison Governors’ Association

But Mr Drury describes risk assessments as an “algorithm tick box” because of “the pressure on offender management units”.

These warnings come at an already embarrassing time for the Prison Service after migrant sex offender Hadush Kebatu was mistakenly freed last month.

This week, it emerged two others have been freed in error since then, amid new release checks.

In response to this report, the Ministry of Justice says it “inherited a justice system in crisis, with prisons days away from collapse” – forcing “firm action to get the situation back under control”.

The government has promised to add 14,000 new prison places by 2031 and introduce sentencing reforms.

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