Cancer innovation is saving lives – but NHS is struggling to meet rising demands
“The moment you have it yourself you hear it everywhere, but for something so prevalent it’s not talked about at all,” says Patrick Keane. His right arm is plugged into a tube that runs up to a bag of clear liquid in a treatment room at the Royal Free Hospital in north London, one of the UK’s largest cancer treatment centres.
The 56-year-old’s future is dependent on the slow drip of chemicals that attack the cancer cells in his body. If the tumour in his bowel can be reduced by chemotherapy, it can then be more easily surgically removed.
Returning to duties last week after his own diagnosis, the King chose to highlight innovations in cancer research and the thousands who like him are living under the shadow of the disease.
Patrick is one. Indeed, he got his cancer diagnosis in late January, around the same time as the King, and he is taking part in an innovative clinical trial that may help future patients.
Patrick Keane is taking part in an innovative clinical trial that may help future patients
In this election year, charities are calling on political parties to produce long-term plans for tackling the disease as part of their manifesto pledges. While innovation is saving lives, there is a looming budget shortfall.
Cancer Research UK, to whom the King became patron last week, estimates there will be a £1bn gap in research funding within the next decade. This is in part due to inflation combined with the cost of living crisis impacting donations to cancer charities.
Add to this that the number of us getting cancer is increasing, projected to go up by a fifth by 2040.
The Royal Free London NHS Trust, which receives the highest number of cancer referrals in London at 50,000 a year, has seen a 10,000 increase in referrals since 2019.
It’s no surprise then that the NHS is missing targets for waiting times between urgent GP referrals and treatment.
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One in two of us will get cancer and, as Patrick knows too well, that word opens up a world of uncertainty. “The word carries so much baggage with it,” he says, and having it can send your mind to “some pretty dark places”.
He talks frankly about the treatment and its side effects, which after his first two rounds, have been minimal. “I didn’t have much of a head of hair to begin with,” he jokes.
Some of his hair has gone in patches, but asked what the hardest thing has been, he doesn’t hesitate: “My father passed away when I was 14. He died of cancer. I have 13-year-old twins so I couldn’t initially shift the thought – is this going to happen again? Passing 48, the age that my father died was a key milestone for me. My children being older than I was when my father passed away was another one.
“Nobody expects their dad to die. It’s a very unreal concept, and I’m not dying – but to try to have that conversation you know – ‘things will be fine.’ It’s very treatable.”
Two weeks after his third round of chemo, scans show the treatment has done its job, Patrick’s surgery can go ahead and is due to happen later this month.
Roopinder Gillmore, lead cancer physician at the Royal Free
More survive cancer as technology advances
Cancer is more treatable now. More of us are surviving it because technology is advancing.
At the Royal Free that ranges from a new cutting-edge £8m PET scanner, which offers a faster more accurate diagnosis, to new drugs offering greater survival chances.
Lead cancer physician at the Royal Free, Roopinder Gillmore, told Sky News: “We are doing surgery quicker, more keyhole robotic surgery in this hospital. We do liver transplants for patients with primary liver cancer, we’re trialling that out in other cancer types which is really exciting.
“We are doing more specialised radiotherapy and for me, my thing is drug treatments, and they are exponentially increasing in terms of what we can offer our patients. The big thing is immunotherapy, we didn’t have that 15 years ago. It has completely changed the outlook for people with lung cancer and skin cancer.”
Backlogs and waiting times have increased
But for all the advances, backlogs and waiting times have built up since the pandemic. The latest NHS figures show 64% of patients received their first treatment within 62 days of an urgent GP referral. The target is 85%.
That stretch on resources has a knock-on impact on patients like 29-year-old Beaux Harris.
Beaux, an actor and dancer who teaches at The Manor Dance Studio in north London, has what is called a mutated BRCA1 gene, which means her chances of getting cancer dramatically increase in her 30s.
She has a 60% chance of getting ovarian cancer and a 90% chance of getting breast cancer.
So she has decided to get a preventative double mastectomy and a hysterectomy but, due to the backlog, she has a long wait.
Beaux Harris has a mutated gene which means her chances of getting cancer dramatically increase in her 30s
‘I feel like I’ve got a ticking time bomb on me’
She says: “I feel like I’ve got a ticking time bomb on me – and it is terrifying. The truth is it doesn’t really feel like a choice when you are presented with a figure like that – it’s like saying would you get on a plane with a 90% chance of it crashing? I know I wouldn’t.”
She has been told that waiting times on the NHS for her preventative treatment is two years at the earliest.
She says people on her online support groups have waited five years. She’s also been told there’s a high chance the operation could be cancelled at the last minute if a high-demand cancer patient needs the slot.
“I could get timed out,” she says. So, she is crowdfunding to get the £50,000 plus she needs to go private.
‘I would love to be worrying about things that every other 29-year-old is worrying about’
She might need more funds if she wants some sort of normality at the end of it.
She says: “If I have a hysterectomy now, I can’t have children. So, I’m also trying to raise money to freeze my eggs. Something that is offered on the NHS to cancer patients, but not to BRCA patients.”
She certainly doesn’t want to wait until she gets cancer. Ovarian cancer is known as the silent killer due to the difficulty in early detection.
Beaux’s grandmother, her mother, and her aunt all died of cancer because of the BRCA1 mutated gene, she hopes to be the first female in her family in generations to survive having it.
“I would love to be worrying about things that every other 29-year-old is worrying about,” she says. “I’ve got some bloody Olivia awards to win!”
Indeed, Beaux is using her talents putting on performances and doing tap dance sessions to raise money for her treatment.
In some ways it is taken for granted that, because it touches so many of us, most of the money raised for cancer research in this country comes from the British public, but charities say the government needs to play a bigger role in ensuring the UK continues to innovate and improve treatment for what remains the defining health issue of our time.
Ramesh lives in fear every day. A police siren is enough to alarm him.
He’s one of up to 400,000 visa overstayers in the UK, one lawyer we spoke to believes.
It’s only an estimate because the Home Office has stopped collecting figures – which were unreliable in the first place.
Britain is being laughed at, one man told us, “because they know it’s a soft country”.
‘Ramesh’ came to the UK from India
We meet Ramesh (not his real name) at a Gurdwara, a Sikh place of worship, where he goes for food and support.
He insists he can’t return to India where he claims he was involved in political activism.
Ramesh says he came to the UK on a student visa in 2023, but it was cancelled when he failed to continue his studies after being involved in a serious accident.
He tells us he is doing cash-in-hand work for people who he knows through the community where he is living and is currently working on a house extension where he gets paid as little as £50 for nine hours labouring.
“It’s very difficult for me to live in the UK without my Indian or Pakistani community – also because there are a lot of Pakistani people who give me work in their houses for cleaning and for household things,” he adds.
‘What will become of people like us?’
Anike has lived in limbo for 12 years.
Now living in Greater Manchester, she came to the UK from Nigeria when her sister Esther was diagnosed with a brain tumour – she had a multi-entry visa but was supposed to leave after three months.
Esther had serious complications from brain surgery and says she is reliant on her sister for care.
Immigration officials are in touch with her because she has to digitally sign in every month.
Anike has had seven failed applications for leave to remain on compassionate grounds refused but is now desperate to have her status settled – afraid of the shifting public mood over migration.
“Everybody is thinking ‘what will become of people like us?'” she adds.
‘It’s a shambles’
The government can’t say with any degree of accuracy how many visa overstayers there are in Britain – no data has been collated for five-and-a-half years.
But piecing together multiple accounts from community leaders and lawyers the picture we’ve built is stark.
Immigration lawyer Harjap Singh Bhangal told us he believed there could be several hundred thousand visa overstayers currently in Britain.
He says: “At this time, there’s definitely in excess of about 200,000 people overstaying in the UK. It might even be closer to 300,000, it could even be 400,000.”
Asked what evidence he has for this he replies: “Every day I see at least one overstayer, any immigration lawyers like me see overstayers and that is the bulk of the work for immigration lawyers.
“The Home Office doesn’t have any accurate data because we don’t have exit controls. It’s a shambles. It’s an institution where every wall in the building is cracked.”
The number of those who are overstaying visas and working cash in hand is also virtually impossible to measure.
‘They know Britain is a soft country’
“They’re laughing at us because they know Britain is a soft country, where you won’t be picked up easily,” says the local man we’ve arranged to meet as part of our investigation.
We’re in Kingsbury in northwest London – an area which people say has been transformed over the past five years as post-Brexit visa opportunities opened up for people coming from South Asia.
‘Mini-Mumbai’
The man we’re talking to lives in the community and helps with events here. He doesn’t want to be identified but raises serious questions about visa abuse.
“Since the last five years, a huge amount of people have come in this country on this visiting visa, and they come with one thing in mind – to overstay and work in cash,” he says.
“This area is easy to live in because they know they can survive. It looks like as if you are walking through mini-Mumbai.”
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‘The system is more than broken’
‘It’s taxpayers who are paying’
And he claims economic migrants are regularly arriving – who’ve paid strangers to pretend they’re a friend or relative in order to obtain a visitor visa to get to Britain.
He says: “I’ve come across so many people who have come this way into this country. It’s widespread. When I talk to these people, they literally tell me, ‘Oh, someone is coming tomorrow, day after tomorrow, someone is coming’.
“Because they’re hidden they may not be claiming benefits, but they can access emergency healthcare and their children can go to school.
“And who is paying for it? It’s the taxpayers who are paying for all this,” says the man we’ve met in north London.
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A Home Office spokesperson said: “We will not tolerate any abuse of our immigration system and anyone found to be breaking the rules will be liable to have enforcement action taken against them.
“In the first year of this government, we have returned 35,000 people with no right to be here – a 13% rise compared to the previous year.
“Arrests and raids for illegal working have soared to their highest levels since records began, up 63% and 51%.”
The government can’t say with accuracy how many visa overstayers there are in Britain – no data has been collated for five-and-a-half years.
Sky News has spoken to immigration lawyers about the numbers, and one believes there could be as many as 400,000 living across the country.
Harjap Singh Bhangal described the situation as a “shambles”.
“The Home Office doesn’t have any accurate data because we don’t have exit controls. It’s a shambles. It’s an institution where every wall in the building is cracked,” he told Sky’s Lisa Holland.
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The visa overstayers in ‘soft’ Britain
Why doesn’t the government know?
The Home Office used to gather data on visa overstayers by effectively checking a list of passport numbers associated with visas against a list of passport numbers of people leaving the UK, taken from airlines and other international travel providers.
If there was a passport number match in the arrivals and departures part of their database, that person was recorded to have left when they should have. If there wasn’t, they were a potential overstayer.
They stopped producing the figures because a combination of Brexit and COVID added complications that made the Home Office conclude they wouldn’t be able to get to a reliable number using the same method.
It’s now four and a half years since EU citizens had freedom of movement to the UK revoked, and more than three and a half years since pandemic-era travel restrictions ended.
And yet we are still waiting to see what a new method might look like.
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The old method wasn’t perfect. If someone changed their passport while in the UK, for example, or if the airline or individual entered the number wrong when they were leaving, there wouldn’t be a match.
The Home Office regarded the statistics as likely overestimating the true number of overstayers, and the Office for National Statistics designated the figures as “experimental” rather than “official” statistics, meaning the conclusions should be treated with caution. But they were a reasonable best guess.
With all that in mind, between April 2016 and March 2020 upwards of 250,000 people were flagged as potential overstayers, equivalent to 63,000 per year.
That’s more than the 190,000 people who are recorded to have arrived in the UK on small boats since 2018.
It represents 3.5% of the seven million visas that expired over that period, so at least 96.5% of people left when they should.
Other Home Office data reveals that more than 13 million visas were issued between 2020 and the end of June 2025, including a record 3.4 million in 2023.
But what we don’t know is how many have expired, which means it’s difficult for us to even guess how many people might have overstayed.
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