A 91-year-old man has become the first person in England to be fitted with a ground-breaking artificial cornea.
Cecil ‘John’ Farley, 91, said his sight was now improving thanks to the procedure, which he underwent after 15 years of suffering from problems with his eyes.
The cornea is the clear outer layer at the front of the eyeball – and is described by the NHS as the “window to the eye”.
A person can suffer from vision problems and pain if the thin transparent covering is damaged by disease or injury – with those affected often left facing a long wait for a human transplant.
However, it is hoped that the artificial device, called EndoArt, will slash waiting times, ease pressure on the NHS and eliminate the risk of the human body rejecting corneas received from an organ donor.
Mr Farley, from Chobham in Surrey, said he was overjoyed by the transplant – in his right eye – because it meant he could continue to see his 83-year-old wife Elizabeth.
He said: “I can still see my wife after 63 years of marriage, we can just carry on as normal and live life as fully as we can.
“It makes your life fuller when your eyes work properly – you don’t realise how debilitating it is until it happens to you.”
Image: Cecil Farley has his new cornea examined. Pic: PA
Before the surgery, Mr Farley had no vision in his right eye – but his sight has slowly been improving ever since the procedure in February.
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He said: “It has made a great difference to my sight. It was very blurred and I couldn’t distinguish a face.
“Now I can see better with it, the brighter the light the better. It’s coming along slowly – they said it could take up to a year.”
The artificial cornea has been compared to a contact lens. The device, which replaces the inner part of the cornea, is surgically attached to the eye by a single stitch and is put in place with a gas bubble.
Patients could see major impact
One of the biggest advantages of using artificial corneas is the huge reduction in waiting time for the procedure. It means patients on the elective backlog who risk further deterioration in their vision can be seen months earlier than they would waiting for a cornea transplant from an organ donor.
But at the moment the artificial cornea operation can only be carried out on patients who meet the “complex eye” criteria. These include patients whose previous human cornea transplant has failed.
Consultant ophthalmologist Tom Poole, who carried out the procedure, is confident the surgery can be rolled out to “virgin eye” patients in the future. These are patients with no previous history of eye surgery.
Mr Poole told me the international ophthalmology community was growing increasingly confident with artificial corneas which are relatively easy to make and their production could be scaled up quite easily.
He and his colleague Hanbin Lee at Frimley Health NHS Foundation Trust have already carried out three more operations since February.
The latest tests on Mr Farley suggest the procedure has been a success. Three more patients have been identified and are listed for surgery.
Only 200 people worldwide, including Mr Farley, have been fitted with an EndoArt so far, but there are hopes it can be more widely rolled out.
Organic cornea transplants usually come from deceased donors. A total of 4,719 were donated to the NHSin 2022/23, according to the latest available figures.
Consultant ophthalmologist Thomas Poole, from Frimley Health NHS Foundation Trust in Surrey, which carried out the procedure, described the artificial cornea as a “great advancement”.
He said there had been fears that Mr Farley was “kind of getting to [his] last hope” after a previous human transplant failed.
Image: Thomas Poole with Mr Farley. Pic: PA
Mr Poole said: “I had a very frank discussion with him before and I said: ‘Look, your graft has failed, you’re back on the waiting list. Because your other eye sees quite well, you’re not a high priority on the waiting list and you could be waiting for another year’.
“He’s in his 90s now and said ‘I just can’t wait that long. Is there anything else?’ And so this sprung to mind.
“I had just read a publication on very good reports from this artificial graft and it was that that made me think actually, maybe we could use this for John.”
Image: Cecil Farley said he was overjoyed he would be able to continue seeing his wife. Pic: PA
Mr Poole and his colleague Hanbin Lee have now successfully given four patients artificial corneas in the last two months and the initial results have shown an improvement in vision.
He added: “Looking forward to the future, I think this may end up replacing human corneas for certain types of corneal graft patients.
“In maybe 10 or 20 years’ time – this may become the norm where we don’t need a human cornea, and we can just take one out of the box.”
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Image: Liverpool’s captain Virgil van Dijk. Pic: Reuters
Image: Liverpool’s Ryan Gravenberch and Cody Gakpo (right) arrive at the funeral of Diogo Jota and Andre Silva. Pic: PA
Jota, 28, leaves behind his wife of only 11 days, Rute Cardoso, and three young children.
His younger brother, 25, was an attacking midfielder for Penafiel in the second tier of Portuguese football.
Liverpool manager Arne Slot, captain Virgil Van Dijk and teammates including Andy Robertson, Conor Bradley, Ryan Gravenberch, Cody Gakpo, Curtis Jones, Darwin Nunez and Joe Gomez were seen at the service.
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Former teammates Jordan Henderson, James Milner and Fabinho were also there.
Van Dijk carried a red wreath with Jota’s number 20, while Robertson had a wreath featuring number 30, Silva’s number at Penafiel.
Image: Manchester United and Portugal player Bruno Fernandes. Pic: PA
Image: Liverpool’s captain Virgil van Dijk and Liverpool’s player Andrew Robertson. Pic: Reuters
Some of Jota’s teammates in the Portuguese national side also attended, including Bruno Fernandes, of Manchester United, Ruben Dias and Bernardo Silva, of Manchester City, Joao Felix and Renato Veiga, of Chelsea, Nelson Semedo, from Wolves, Joao Moutinho and Rui Patricio.
Ruben Neves was one of the pallbearers after flying in from Florida where he played for Al Hilal in the Club World Cup quarter-final on Friday night.
‘More than a friend’
In a post published on Instagram before the service, he told Jota he had been “more than a friend, we’re family, and we won’t stop being that way just because you’ve decided to sign a contract a little further away from us!”
Jota’s fellow Liverpool midfielder, Alexis Mac Allister, said on Instagram: “I can’t believe it. I’ll always remember your smiles, your anger, your intelligence, your camaraderie, and everything that made you a person. It hurts so much; we’ll miss you. Rest in peace, dear Diogo.”
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Porto FC president Andre Villas-Boas and Portugal national team manager Roberto Martinez were also in attendance.
‘With us forever’
Speaking after the ceremony, Martinez said the period since their deaths had been “really, really sad days, as you can imagine, but today we showed we are a large, close family.
“Their spirit will be with us forever.”
The service was private, but the words spoken by the Bishop of Porto, Manuel Linda, were broadcast to those standing outside the church.
He told Jota’s children, who were not at the service, that he was praying for them specifically, as well as their mother and grandparents.
“There are no words, but there are feelings,” he said, adding: “We also suffer a lot and we are with you emotionally.”
The brothers died after a Lamborghini they were travelling in burst into flames following a suspected tyre blowout in the early hours of Thursday morning.
No other vehicles are said to have been involved in the incident.
Liverpool have delayed the return of their players for pre-season following Jota’s death and players past and present paid tribute to him and his brother on social media.
Rachel Reeves has hinted that taxes are likely to be raised this autumn after a major U-turn on the government’s controversial welfare bill.
Sir Keir Starmer’s Universal Credit and Personal Independent Payment Bill passed through the House of Commons on Tuesday after multiple concessions and threats of a major rebellion.
MPs ended up voting for only one part of the plan: a cut to universal credit (UC) sickness benefits for new claimants from £97 a week to £50 from 2026/7.
Initially aimed at saving £5.5bn, it now leaves the government with an estimated £5.5bn black hole – close to breaching Ms Reeves’s fiscal rules set out last year.
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Rachel Reeves’s fiscal dilemma
In an interview with The Guardian, the chancellor did not rule out tax rises later in the year, saying there were “costs” to watering down the welfare bill.
“I’m not going to [rule out tax rises], because it would be irresponsible for a chancellor to do that,” Ms Reeves told the outlet.
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“We took the decisions last year to draw a line under unfunded commitments and economic mismanagement.
“So we’ll never have to do something like that again. But there are costs to what happened.”
Meanwhile, The Times reported that, ahead of the Commons vote on the welfare bill, Ms Reeves told cabinet ministers the decision to offer concessions would mean taxes would have to be raised.
The outlet reported that the chancellor said the tax rises would be smaller than those announced in the 2024 budget, but that she is expected to have to raise tens of billions more.
Sir Keir did not explicitly say that she would, and Ms Badenoch interjected to say: “How awful for the chancellor that he couldn’t confirm that she would stay in place.”
In her first comments after the incident, Ms Reeves said she was having a “tough day” before adding: “People saw I was upset, but that was yesterday.
“Today’s a new day and I’m just cracking on with the job.”
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“In PMQs, it is bang, bang, bang,” he said. “That’s what it was yesterday.
“And therefore, I was probably the last to appreciate anything else going on in the chamber, and that’s just a straightforward human explanation, common sense explanation.”
The family and friends of Diogo Jota and his brother Andre Silva have been joined by Liverpool stars past and present and other Portuguese players at the pair’s funeral near Porto.
Pictures below show the funeral at the Igreja Matriz de Gondomar church in the town of Gondomar near Porto. Click here for our liveblog coverage of the day’s events.
Image: Diogo Jota’s wife Rute Cardoso arrives for the funeral of him and his brother Andre Silva. Pic: Reuters
Image: Liverpool players Virgil van Dijk and Andrew Robertson arrive for the funeral. Pic: Reuters
Image: Van Dijk carried a wreath with Jota’s number 20 while Andrew Robertson’s had a 30 for Andre Silva. Pic: Reuters
Image: Liverpool captain Virgil van Dijk. Pic: Reuters
Image: Portugal player Ruben Neves arrives at the funeral. Pic: PA
Image: Liverpool’s Joe Gomez and manager Arne Slot arrive at the funeral of Diogo Jota and Andre Silva. Pic; PA
Image: Liverpool’s Ryan Gravenberch and Cody Gakpo (right) arrive at the funeral of Diogo Jota and Andre Silva
Image: Manchester City and Portugal player Bernardo Silva arrives at the funeral. Pic: AP
Image: The coffins are carried to the church. Pic: PA
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2:27
Miguell Rocha played with Jota for around ten years with Gondomar Sport Clube in Portugal.
Image: People line up to enter the church. Pic: AP
Image: Pallbearers carry the coffins of Diogo Jota and his brother Andre Silva
Image: Pic: Reuters
Image: Pic: AP
Image: People gather outside the Chapel of the Resurrection. Pic: Reuters
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0:22
The former captain was seen wiping away tears as he read messages and laid his tribute down.
Image: Fans pay their respects outside Anfield in Liverpool. Pic: Reuters
Image: A board with a picture of Diogo Jota outside Anfield Stadium. Pic: PA
Image: The coffins are carried to the church. Pic: PA