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A weight-loss injection could slow ageing and offer benefits far beyond what was imagined, researchers have suggested.

Semaglutide, which is available under brand names Wegovy and Ozempic, cuts the risk of death in overweight people with cardiovascular disease, according to several studies.

While Wegovy is available through the NHS for weight loss if certain criteria are met, Ozempic is currently only prescribed for type 2 diabetes – though both contain semaglitude.

Published in JACC, the flagship journal of the American College of Cardiology, the research shows semaglutide could have “far-reaching benefits beyond what we initially imagined”.

That’s according to Professor Harlan M Krumholz from the Yale School of Medicine, who is quoted in multiple reports as saying: “Is it a fountain of youth?”

“I would say if you’re improving someone’s cardiometabolic health substantially, then you are putting them in a position to live longer and better,” he said.

“It’s not just avoiding heart attacks. These are health promoters. It wouldn’t surprise me that improving people’s health this way actually slows down the ageing process.”

Researchers found participants who took semaglutide died at a lower rate from all causes, as well from cardiovascular causes and COVID-19.

The drug was also found to improve heart failure symptoms.

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Participants – all 17,604 of them – were aged 45 or older, overweight, had established cardiovascular disease but not diabetes and were tracked for more than three years.

A total of 833 participants died during the study, with 58% of the deaths related to cardiovascular causes and 42% from others.

Infection was the most common cause of death beyond cardiovascular, but it occurred at a lower rate in the group taking semaglutide than in those taking a placebo.

Wegovy, which is administered through an injection, is available on the NHS, but only through specialist weight management services.

Read more:
Ozempic to Wegovy – what are the weight loss injections?
Stephen Fry says Ozempic made him vomit five times a day

Patients with a BMI over 30, or more than 27 with one weight-related comorbidity, can access the drug.

Semaglutide works by mimicking the hormone GLP-1 (glucagon-like peptide one) to manage hunger and slow down digestion.

It is also the active ingredient in Ozempic, which was the first of the weight loss jabs to blow up on TikTok.

The studies were presented at the European Society of Cardiology Conference 2024 in London.

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All GP surgeries in England must offer online booking from today

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All GP surgeries in England must offer online booking from today

All GP surgeries in England are required to offer online appointment bookings from today.

Practices must keep their websites and app services available from at least 8am to 6.30pm, Monday through Friday, for non-urgent appointments, medication queries and admin requests.

Many surgeries are already offering online bookings and consultations, but services are typically less effective in working-class areas.

The Department of Health and Social Care says there is a lack of consistency, as some surgeries that offer online services are choosing to switch the function off during busier periods.

The British Medical Association (BMA) has argued safeguards have not been put in place, nor have extra staff been brought in to manage what it anticipates will be a “barrage of online requests.”

The BMA has said GPs are considering a range of actions after voting to enter a dispute with the government over the plan.

Health Secretary Wes Streeting has urged the BMA to embrace the plan, saying the union’s resistance is “a real disservice to so many GPs” who have already introduced the service.

Health Secretary Wes Streeting says booking a GP appointment should be as easy as booking a takeaway. Pic: PA
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Health Secretary Wes Streeting says booking a GP appointment should be as easy as booking a takeaway. Pic: PA

‘As easy as booking a takeaway’

The minister said the government will help practices that need assistance to implement the plan, “but we’ve got to modernise”.

Mr Streeting told the Labour Party conference: “Many GPs already offer this service because they’ve changed with the times.

“Why shouldn’t be booking a GP appointment be as easy as booking a delivery, a taxi, or a takeaway? And our policy comes alongside a billion pounds of extra funding for general practice and 2,000 extra GPs.

“Yet the BMA threatens to oppose it in 2025. Well, I’ll give you this warning; if we give in to the forces of conservatism, they will turn the NHS into a museum of 20th century healthcare.”

Read more from Sky News:
Starmer will take ‘no more lectures’ from Farage
Streeting says Labour ‘need Angela Rayner back’

The measure is part of the broader government pledge to transform the NHS.

Sir Keir Starmer has revealed plans to establish a nationwide “online hospital” by 2027, enabling patients to receive treatment and care from home.

The government said the initiative could provide up to 8.5 million additional NHS appointments within its first three years.

Available via the NHS app, it will allow patients to schedule in-person procedures at local hospitals, surgical hubs or diagnostic centres, reducing delays.

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Farage isn’t racist, says PM – as he’s challenged over Trump’s ‘Sharia law’ comment

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Farage isn't racist, says PM - as he's challenged over Trump's 'Sharia law' comment

Sir Keir Starmer has said he does not believe Nigel Farage or Reform voters are racist – and also refused to label Donald Trump’s claim that London wants “Sharia law” as such.

The prime minister told Sky News political editor Beth Rigby the president’s claim – made while criticising the capital’s mayor, Sir Sadiq Khan, during a UN summit last week – was “nonsense”.

Asked if it was racist, considering Sir Sadiq is a Muslim, Sir Keir said: “I have been really clear that the idea that in London we’re introducing Sharia law is rubbish.”

He said the mayor – who has branded Mr Trump “racist, sexist, misogynistic” – was doing a “very good job”, but also pointed to his “very good relationship” with the president.

Sir Keir also insisted he does not think Mr Farage or Reform supporters are racist, after targeting the party in his Labour conference speech and claiming its leader “hates Britain”.

Earlier in the week, Sir Keir called Reform’s freshly announced immigration policies “racist” and “immoral”.

Asked if he thinks Mr Farage is a racist, he said: “No, nor do I think Reform voters are racist.

“They’re concerned about things like our borders, they’re frustrated about the pace of change.

“So I’m not for a moment suggesting that they are racist.”

He said he was “talking about a particular policy”, which would see Reform axe the right of migrants to apply for indefinite leave to remain, ban anyone who is not a UK citizen from claiming benefits, and force those applying for UK citizenship to renounce other citizenship.

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How did the PM perform at conference?

Reform ‘taking country down road of toxic division’

Sir Keir also refused to say whether he thinks Mr Farage is dangerous, saying: “I think the fight at the next election is going to define us as a country for years to come.

“I think it’s a dangerous moment for the country.”

He said he would not “get into labelling the man”.

“I’m talking about the ideas and what he stands for and what I stand for,” he added.

“I think that taking our country down the road of toxic division where you don’t want to fix problems because if they’re fixed, you lose your reason to exist, I think that is dangerous for our country.”

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Starmer’s ‘anti-Reform party’ gamble

Farage: Starmer unfit to be PM

Mr Farage reacted to Sir Keir’s speech by accusing him of being “unfit to be the prime minister of our country”.

“I used to think the prime minister was a decent man, somebody that I could talk to and chat to,” he said.

“We might disagree on our worldview, but I thought he was a profoundly decent human being. I am completely shocked at his behaviour.

“I hope when he wakes up tomorrow morning he feels ashamed of what he has done. This is a desperate last throw of the dice for the prime minister who’s in deep trouble, a prime minister who can’t even command the support of half of his own party.

“But I’m sorry to say, I now believe he is unfit to be the prime minister of our country.”

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Princess Anne makes surprise Ukraine visit – and leaves a personal tribute

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Princess Anne makes surprise Ukraine visit - and leaves a personal tribute

Princess Anne has placed a toy bear as a poignant tribute at a children’s memorial in Ukraine, during an unexpected visit to the war-ravaged country where she also met Volodymyr Zelenskyy.

The King’s sister travelled to the capital Kyiv on Tuesday, at the request of the Foreign Office, in a show of solidarity with children and families facing the horrors of the Russian invasion.

The Princess Royal met Mr Zelenskyy to discuss the UK’s support for Ukraine and its ongoing resistance.

The Princess Royal and First Lady Olena Zelenska laid soft toys during a visit to a memorial for children killed in the war. Pic: PA
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The Princess Royal and First Lady Olena Zelenska laid soft toys during a visit to a memorial for children killed in the war. Pic: PA

Anne’s secret visit, which was not publicised beforehand for security reasons, came just two days after a Russian aerial bombardment killed at least four people in Kyiv, including a 12-year-old girl, and injured at least 70 others.

The attack, which lasted more than 12 hours, was one of the heaviest in recent months.

The purpose of her trip was to highlight the traumatic experiences of children living on the frontline, Buckingham Palace said.

Joining First Lady Olena Zelenska at the children’s memorial, Anne left the teddy in tribute to youngsters killed in the conflict, saying her daughter Zara Tindall had the same bear.

As the 75-year-old princess stepped back after placing the traditional-looking teddy at the base of the memorial alongside scores of other cuddly toys, she told Mrs Zelenska: “That was one that my daughter had.”

Mrs Zelenska also left a bear in tribute.

Anne is the latest British royal to make a trip to Kyiv. Pic: PA
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Anne is the latest British royal to make a trip to Kyiv. Pic: PA

The site commemorates more than 650 children who have died since the start of the conflict in 2022.

In Kyiv, she also met female police and armed forces representatives and heard about their key role protecting women and children.

Visiting the Child Rights Protection Centre, she spoke to families and children who have been returned and reintegrated, and met some of those working to return more Ukrainian children.

Read more:
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Moldova’s pro-EU party wins elections against Russia-leaning rivals

Princess Anne spoke to young people who lived under occupation. Pic: PA
Image:
Princess Anne spoke to young people who lived under occupation. Pic: PA

The Princess Royal met Ukrainian war veterans relaxing in a salt therapy room at a rehabilitation centre. Pic: PA
Image:
The Princess Royal met Ukrainian war veterans relaxing in a salt therapy room at a rehabilitation centre. Pic: PA

More than 19,500 Ukrainian children have been forcibly transferred or deported by the Russian authorities to Russia and the occupied territories of Ukraine.

Princess Anne is the second working royal to visit Ukraine.

In April last year, the Duchess of Edinburgh was the first to go and bring a letter of support from the King.

Anne’s trip also follows that of her nephew Prince Harry, who made a surprise visit to the Ukrainian capital just over two weeks ago with a team from his Invictus Games Foundation.

Anne also visited a rehabilitation centre, where she met Ukrainian veterans returning from the frontline.

The King has met Mr Zelenskyy a number of times and marked the country’s independence day in August by sending a message of solidarity.

During Donald Trump’s recent state visit to the UK, Charles also took the opportunity to stress the importance of supporting Ukraine.

He told the US president in his banquet speech: “Today, as tyranny once again threatens Europe, we and our allies stand together in support of Ukraine, to deter aggression and secure peace.”

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