Donald Trump has said the US is having direct talks with Iran over its nuclear programme – stating Iran will be in “great danger” if the negotiations fail.

The president has insisted Tehran cannot get nuclear weapons.

But Iran almost immediately contradicted the president insisting the talks due to take place in Oman on Saturday would be conducted through an intermediary.

Iran had pushed back against the US president’s demand that it enter negotiations over its nuclear programme or be bombed, but speaking at the White House on Monday, Mr Trump said: “We’re having direct talks with Iran, and they’ve started.

“It’ll go on Saturday,” he continued. “We have a very big meeting, and we’ll see what can happen. And I think everybody agrees that doing a deal would be preferable.”

When pressed for more details on the talks, the US president said they are taking place “at almost the highest level”, without specifying who would take part or where they would be held.

“Hopefully those talks will be successful, it would be in Iran’s best interests if they are successful,” he said. “We hope that’s going to happen.

Speaking in the Oval Office on Monday, Mr Trump said Iran “cannot have a nuclear weapon, and if the talks aren’t successful, I actually think it will be a very bad day for Iran”.

However, Mr Trump’s bullish comments were not matched by Tehran. Iran’s Foreign Minister Abbas Araghchi posted on X that indirect high-level talks would be held in Oman, adding: “It is as much an opportunity as it is a test. The ball is in America’s court.”

On Tuesday, Iran’s state media said the talks would be led by Mr Araghchi and US presidential envoy Steve Witkoff, with Oman’s foreign minister, Badr al Busaidi, acting as intermediary.

Mr Trump’s previous warnings of possible military action against Iran heightened already tense nerves across the Middle East.

He has said he would prefer a deal over military confrontation and in March wrote to Iran’s supreme leader Ayatollah Ali Khamenei to suggest talks. Iranian officials at the time said Tehran would not be bullied into negotiations.

Direct talks would not occur without the explicit approval of Iran’s supreme leader, who said in February that negotiations with the US were “not smart, wise, or honourable”.

During his first White House term, Mr Trump withdrew the US from a deal between Iran and world powers designed to curb Iran’s nuclear work in exchange for sanctions relief.

He also reimposed US sanctions.

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Iran has since far surpassed that deal’s limits on uranium enrichment.

Tehran insists its nuclear programme is wholly for civilian energy purposes but Western powers accuse it of having a clandestine agenda.

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Benjamin Netanyahu’s White House visit – his second in just over two months – was also due to include a news conference but this was cancelled earlier on Monday.

Officials said the decision was made because the Israeli prime minister and Mr Trump had “two back-to-back media availabilities (the greeting in the Oval Office and the formal news conference), and they wanted to streamline things”.

The Palestine Red Crescent Society (PRCS) has demanded an independent investigation into the “atrocious” deaths of 15 aid workers killed by Israeli troops in Gaza in March.

The group’s president, Dr Younis al Khatib, said he had asked the UN Security Council to form an investigation committee into the “intentional killing of the medics”.

In response to Sky’s Alistair Bunkall, spokesman David Mencer claimed the killings were the result of Hamas hiding among civilians and using them as human shields.

But speaking in Ramallah, Dr al Khatib said those responsible must be held “accountable for these crimes” via international humanitarian law and the Geneva Convention.

“It’s not enough to comfort us with condolences and nice words of investigation and accountability. There has to be action taken,” he added.

He urged an “independent and thorough investigation of this atrocious crime” and that “no one should be above the law”.

“So many questions being asked of the Israelis,” he said.

“Why were they killed? Why did you destroy the ambulances after killing them? Why did you try to dig deep and hide the ambulances? They have to answer for that.”

The Israel Defence Forces (IDF) said on Monday that a preliminary inquiry into the shooting “indicated the troops opened fire due to a perceived threat following a previous encounter in the area”.

The IDF added that “six of the individuals killed in the incident were identified as Hamas terrorists”.

It comes after footage at the weekend showed the moment the aid workers were killed, with ambulances and fire insignia clearly visible and red lights flashing.

The paramedic filming, later found with a bullet in his head, is heard saying there are Israelis present and reciting a declaration of faith often used before someone dies.

He adds: “Forgive me, mother, this is the path I chose mother, to help people, forgive me, mother, I swear I chose this path only to help people.”

The Israeli military originally claimed the vehicles – which were travelling north of Rafah on 23 March – didn’t have headlights or emergency signals on and were targeted as they looked “suspicious”.

An IDF investigation is ongoing, but an Israeli government spokesman claimed on Monday that “six Hamas terrorists” were among those killed.

Mr Mencer said: “IDF soldiers opened fire at a distance at vehicles moving suspiciously in their direction.

“Among the dead were six Hamas terrorists – what were Hamas terrorists doing in ambulances? The incident was reported in real time to UN officials.”

He claimed there were “many documented occasions” when Hamas had used ambulances as cover.

An evacuation order was also in place at the time, which meant moving vehicles were prohibited, according to Israel.

The head of the UN’s humanitarian affairs office, Jonathan Whittall, said the 15 people were found in a “mass grave” in the sand.

He said those killed comprised eight members of the PRCS, six civil defence members and one UN employee.

Dylan Winder, from the International Federation of Red Cross and Red Crescent Societies (IFRC), said it was “outraged at the deaths” and that “even in the most complex conflict zones, there are rules”.

“They were humanitarians. They wore emblems that should have been protected. Their ambulances were clearly marked, and they should have returned to their families. They did not,” he said.

Until five weeks ago, Arturo Suarez was a professional singer, performing in the United States as he waited for his asylum claim to be processed.

Originally from Venezuela, he had entered the US through proper, legal channels.

But he is now imprisoned in a notorious jail in El Salvador, sent there by the Trump administration, despite seemingly never having faced trial or committed any crime. The White House claims he is a gang member but has not provided evidence to support this allegation.

His brother, Nelson Suarez, told Sky News he believes his brother’s only “crime” is being Venezuelan and having tattoos.

“He is not a gang member,” Nelson says, adamantly, “I’ve come to the conclusion that it has to be because of the tattoos. If you don’t have a criminal record, you haven’t committed any crime in the United States, what other reason could there be? Because you’re Venezuelan?”

Arturo, 34, was recording a music video inside a house in March when he was arrested by immigration agents.

He was first taken to a deportation centre in El Paso, Texas, and then, it appears, put on to a military flight to El Salvador.

His family have not heard from him since. Lawyers and immigrant rights groups have been unable to make contact with any of the more than 200 Venezuelan men sent to the CECOT prison, which holds members of the MS-13 and Tren de Aragua gangs.

Tattoo clue to Arturo Suarez’s whereabouts

Nelson learned his brother is – most likely – in CECOT only because of a photograph he spotted on a news website of a group of inmates, with their hands and feet cuffed, heads shaved and bodies shackled together.

“You can see the hummingbird tattoo on his neck,” Nelson says, pointing to the picture. He says Arturo wanted a hummingbird in memory of their late mother. Arturo has 33 tattoos in total, including a piano, poems and verses from the Bible.

It could be that one, or more, of those tattoos landed him at the centre of President Trump’s anti-immigration showpiece. Nelson shows me documents which indicate that Arturo did not have a criminal record in Venezuela, Chile, Colombia or the United States, the four countries he has lived in.

Sky News contacted the White House, the Department of Homeland Security (DHS), and Immigration and Customs Enforcement (ICE) for a response to Arturo’s case but have not heard back.

In March, Donald Trump signed the Alien Enemies Act, a law from 1798 which has been invoked just three times before, in wartime.

It allows the president to detain and deport immigrants living legally in the US if they are from countries deemed “enemies” of the government. In this instance, Mr Trump claimed the Venezuelan gang Tren de Aragua had “infiltrated the United States” and was “conducting irregular warfare”.

Gang symbol tattoos

Immigration officials have centred on certain tattoos being gang symbols. Immigration officers were provided with a document called the “Alien Enemy Validation Guide”, according to a court filing from the American Civil Liberties Union. The document provides a point-based system to determine if an immigrant in custody “may be validated” as a gang member.

Migrants who score six points and higher may be designated as members of the Tren de Aragua gang, according to the document. Tattoos which fall under a “symbolism” category score four points and social media posts “displaying” gang symbols are two points. Tattoos considered suspicious, according to the document, include crowns, stars and the Michael Jordan Jumpman logo.

Jerce Reyes Barrios’s story

Another of the men sent to CECOT prison is 36-year-old Jerce Reyes Barrios, who fled Venezuela last year after marching in anti-government protests. He is a former footballer and football coach.

His lawyer, Linette Tobin, told Sky News that Reyes Barrios entered the US legally after waiting in Mexico for four months for an immigration appointment and then presenting himself at the border.

She says he was detained in a maximum security prison in the US while awaiting his asylum appointment. But before that appointment happened, he was flown to the El Salvador prison.

Ms Tobin says the DHS deported Reyes Barrios because they designated him a Tren De Aragua gang member based on two pieces of evidence.

The first, she says, is a tattoo of the Real Madrid football team logo surrounded by rosary beads. She has since obtained a declaration from the tattoo artist stating that Reyes Barrios just wanted an image which depicted his favourite team.

The second piece of evidence, she says, is a photograph, which she shows me, of Reyes Barrios in a hot tub with friends when he was a college student 13 years ago.

He is making a gesture which could be interpreted as “rock and roll”, but which she says has been interpreted as a gang symbol.

Distraught family in despair

Reyes Barrios has no criminal record in his home country. “I’ve never known anything like this,” Ms Tobin says.

“My client was deported to a third country and we have no way of getting in touch with him. His family are distraught and in despair, they cry a lot, not knowing what is going on with him. We want him returned to the United States to have a hearing and due process.”

Ms Tobin says she and other lawyers representing men sent to the El Salvador prison are trying to establish a UN working group on enforced disappearances to do a wellness check on them because the prison is completely “incommunicado”.

Sky News contacted the DHS for comment about Reyes Barrios’s case but did not receive a response. The DHS previously issued a statement declaring that “DHS intelligence assessments go well beyond just gang-affiliated tattoos. This man’s own social media indicates he is a member of Tren de Aragua”.

Reyes Barrios has an immigration hearing scheduled for 17 April, Ms Tobin says, which the Trump administration is trying to dismiss on the grounds that he is not in the US anymore.

In the meantime, children he used to coach football for in his hometown of Machiques in Venezuela have been holding a prayer vigil for him and calling for his release.

The secretary of the DHS, Kristi Noem, visited CECOT last month and posed for photos standing in front of inmates behind bars.

“Do not come to our country illegally,” she said, “you will be removed, and you will be prosecuted.” Donald Trump had promised during his election campaign to clamp down on immigration, railing against undocumented immigrants and claiming immigrants are “poisoning the blood of our country”.

I ask Arturo Suarez’s brother, Nelson, how he felt watching Ms Noem posing in the prison, knowing that his brother might be close by.

“I feel bad,” he says, “I feel horrible, because in those images we only see criminals. With my brother, I feel it is more a political issue. They needed numbers, they said, these are the numbers, and now, let’s throw them to the lions.”

Kilmar Abrego Garcia’s story

The Trump administration has admitted that at least one man sent to the El Salvador jail was sent by “administrative error”. Kilmar Abrego Garcia, who was living in Maryland, was sent to CECOT despite a judge’s earlier ruling in 2019 that granted him legal protection to stay in the US.

The White House has alleged Garcia is an MS-13 gang member, but his lawyers argued there is no evidence to prove this.

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A federal judge has ordered Garcia must be returned to the US by Monday 7 April. In a post on X, White House deputy chief of staff Stephen Miller referred to the judge as a “Marxist”, who “now thinks she’s president of El Salvador”.

White House press secretary Karoline Leavitt said: “We suggest the judge contact President Bukele because we are unaware of the judge having jurisdiction or authority over the country of El Salvador.”