A “game-changer” pill is to be offered to tens of thousands of smokers in England who are trying to quit.
Varenicline can be more effective than nicotine-replacement gum or patches, and as effective as vapes, in helping people to stop smoking, according to NHS England.
The daily pill is said to reduce cravings and the pleasurable effects of nicotine that keep people addicted.
It also helps with withdrawal symptoms such as irritability or sleeping problems and patients usually take a 12-week course.
It’s estimated it could help more than 85,000 people per year and prevent up to 9,500 smoking-related deaths over the next five years, according to University College London (UCL).
Varenicline will become another option for people using NHS stop smoking services in England.
A branded version of the smoking cessation pill – known as Champix – was previously prescribed, but then withdrawn by Pfizer in 2021 as a precaution after an impurity was discovered.
However, the NHS said a generic version of the drug, from pharmaceutical firm Teva UK, has now been approved as safe by the Medicines Health and Regulatory Authority (MHRA).
It said another pill that works in a similar way, cytisine, is also being reviewed by the National Institute for Health and Care Excellence (NICE) and could be made available in the future.
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Supplying varenicline is part of an effort to make more effective treatments available while saving more than £500m for the taxpayer, said NHS England chief executive Amanda Pritchard.
In a speech later, she will say the pill could be “a game-changer” for smokers. Meanwhile, Health Secretary Wes Streeting said it would save lives and millions of pounds for the NHS.
“Taken alongside our tobacco and vapes bill, the government and NHS are building a healthy society to help power a healthy economy,” said Mr Streeting.
Around six million people – one in eight UK adults – are smokers and there were more than 400,000 hospital admissions in England attributed to smoking in 2022-23, according to the NHS.
Around one in six (16%) of all admissions for respiratory diseases were estimated to be smoking-related, while it also caused 8% of admissions for cancers and 7% for cardiovascular disease.
Each year, the NHS spends around £2.5bn on treating health issues caused by smoking – the leading cause of preventable illness and deaths.
Sir Keir Starmer has said stability in the Middle East is “a priority” following US strikes on Iran’s nuclear facilities, as the world has reacted to the attack.
The prime minister also called on Iran to “return to the negotiating table” to “reach a diplomatic solution to end this crisis”.
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2:30
US strikes on Iran explained
In a statement, Sir Keir said: “Iran’s nuclear programme is a grave threat to international security.
“Iran can never be allowed to develop a nuclear weapon, and the US has taken action to alleviate that threat.
“The situation in the Middle East remains volatile and stability in the region is a priority.
“We call on Iran to return to the negotiating table and reach a diplomatic solution to end this crisis.”
The UK was not involved in the strikes but was informed about them in advance by the US, Business Minister Jonathan Reynolds told Sky News’ Sunday Morning with Trevor Phillips.
Sir Keir and Foreign Secretary David Lammy had been pushing for a diplomatic solution. On Thursday, the prime minister warned of a “real risk of escalation” in the conflict.
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3:34
Trump: Iran strikes ‘spectacular success’
The US struck three sites in Iran early on Sunday morning, with Donald Trump boasting the country’s key nuclear sites were “completely and fully obliterated” in an address to the nation from the White House and warned there could be further strikes if Iran retaliates.
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1:20
‘Trump’s bold decision will change history’
Netanyahu praises Trump
Israel‘s Prime Minister Benjamin Netanyahu praised Mr Trump for the strikes, saying: “Your bold decision to target Iran’s nuclear facilities with the awesome and righteous might of the United States will change history…
“History will record that President Trump acted to deny the world’s most dangerous regime the world’s most dangerous weapons.”
UN secretary-general ‘gravely alarmed’ by US attack
But UN secretary general Antonio Guterres said he was “gravely alarmed by the use of force” by the US against Iran.
“This is a dangerous escalation in a region already on the edge – and a direct threat to international peace and security. There is a growing risk that this conflict could rapidly get out of control – with catastrophic consequences for civilians, the region, and the world.”
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European Union foreign policy chief Kaja Kallas urged all sides to step back and return to the negotiating table. “Iran must not be allowed to develop a nuclear weapon,” she said in a post on X.
“I urge all sides to step back, return to the negotiating table and prevent further escalation,” she said, adding that EU foreign ministers will discuss the situation tomorrow.
Image: Cuba’s President Miguel Diaz-Canel. Pic: Reuters
How the world reacted to the strikes
Cuba’s President Miguel Diaz-Canel said on X: “We strongly condemn the US bombing of Iran’s nuclear facilities, which constitutes a dangerous escalation of the conflict in the Middle East.
“The aggression seriously violates the UN Charter and international law and plunges humanity into a crisis with irreversible consequences.”
Venezuela’s foreign minister Yvan Gil said his country’s government “condemns US military aggression” and “demands an immediate cessation of hostilities”.
In a statement, an Australian government spokesperson said Iran’s nuclear and ballistic missile programme “has been a threat to international peace and security”.
Image: Japan’s Prime Minister Shigeru Isiba. Pic: Reuters
Japan’s Prime Minister Shigeru Ishiba said it is “crucial that there be a quick de-escalation of the conflict”.
Italy’s foreign minister Antonio Tajani said after the attack that his country’s government hopes “a de-escalation can begin and Iran can sit down at the negotiating table”.
The US attack came after more than a week of strikes by Israel, which have significantly degraded Iran’s air defences and offensive missile capabilities, and damaged its nuclear enrichment facilities.
Israel’s strikes on Iran have killed at least 865 people and wounded 3,396 others, according to the Washington-based group Human Rights Activists. The group said of those killed, 365 were civilians and 215 were security force personnel.
Since the local elections Reform UK has had no shortage of good polls.
But a new one suggests Nigel Farage‘s party has a chance not only of winning the next election, but of claiming a decent Commons majority, too.
In February, Reform topped a Sky News/YouGov poll for the first time, with Nigel Farage’s party edging in front on 25%, Labour pushed into second on 24%, with the Tories on 21%.
But a fresh one from Ipsos puts Reform on 34%, nine points ahead of Labour on 25%, with the Conservatives a distant third on 15%.
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16:03
Zia Yusuf: I sent a tweet I regretted
While the other parties are flatlining, Reform appears to be pushing boundaries.
Were these figures to be replicated across the country at a general election, with every constituency behaving the same way, then Reform could win as many as 340 seats, giving it a majority of 30, Sky News analysis suggests.
Labour could be reduced to 176 seats, down 236 on last year’s election, while the Tories would hit a record low of 12 seats.
But polling should always be taken with a pinch of salt and with the firm acknowledgement that there is not an election coming any time soon.
Conservative backbenchers might also tell you publicly that opinion polls are notoriously difficult to translate into seat numbers because voting percentages in individual constituencies can vary hugely from the overall average.
But the truth is that the symbolism of Reform UK topping another poll is likely to be noticed by MPs from all parties, especially backbench Conservatives who have actively been hoping their leader, Kemi Badenoch, can help them climb the polls and bring the party back into public favour.
Politics is a brutal game and when it comes to toppling underwhelming party leaders, the Tories are more ruthless than most. One wonders how many of these polls Mrs Badenoch’s party will allow her to endure.
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As the party approaches a year since its major victory, it will not have much to celebrate if these numbers are anything to go by.
According to this survey, only 19% are satisfied with the job Sir Keir Starmer is doing as prime minister, with 73% dissatisfied.
And the figure of 25% of voters intending to vote Labour is a level not seen since October 2019.
While abstract to much of the public, polling can often shape not only the chatter inside Westminster but how and when plots by MPs begin.
For Reform UK, this is a much-needed morale boost after a surprise resignation by their former Chairman Zia Yusuf, and then an almost immediate U-turn back into the party.
And Kemi Badenoch – who said during her leadership campaign that the Conservatives needed to go back to first principles and that this would take time – will be wondering, seven-and-a-half months after winning the leadership, how much time she really has left.
Ipsos interviewed a representative probability sample of 1,180 British adults aged 18+, via the Ipsos UK KnowledgePanel. Data was collected between 30 May-4 June 2025.
The impending ban on protest group Palestine Action has divided opinion – described as both “outrageous” and “long overdue”.
Home Secretary Yvette Cooper is expected to take the step after the group broke into RAF Brize Norton in Oxfordshire on e-scooters and sprayed two Voyager planes with red paint.
The prime minister described the attack as “outrageous” and a rapid review of security at MoD bases is under way.
It was the latest protest in a five-year campaign from Palestine Action (PA) that has targeted arms manufacturers, financial institutions, political figures and government buildings.
Red spray paint has become its signature.
Image: Damage to planes at Brize Norton
On its website, PA says it is a “direct action movement” committed to ending “global participation” in what it calls Israel’s “genocidal and apartheid regime”.
It adds that it uses “disruptive tactics” to target “corporate enablers of the Israeli military-industrial complex”.
Banning the group would make membership of it illegal. It would be treated as a terrorist organisation.
Saeed Taji Farouky, a spokesman for PA, told Sky News that potential proscription was “unfair”, adding that it was “ludicrous” that a “civil society direct action group” could end up on the same list as ISIS.
He added: “It’s not logical, it’s not even consistent with the British legal definition of terrorism, it’s a reaction that’s been taken overnight, with almost no discussion or debate.
“The whole thing is incredibly worrying, mostly for what it means about British law in general, about undermining the very basis of British democracy and the rule of law.”
There are “no circumstances” under which the two people who breached Brize Norton would be handed over to the police, he said.
Singer-songwriter Paloma Faith, who spoke at a pro-Palestine rally in Whitehall in central London on Saturday, told Sky News she was “devastated” by the move.
Image: Paloma Faith spoke at the pro-Palestine rally
“I have met some of the people who have friends in that group. They are young students and they are basically trying to do something because they feel that our government is failing them.”
She added that “everyone” wants to end what she described as a “massacre” in Gaza.
Israel says its military campaign in Gaza is a way of defending itself against Hamas, which killed more than a thousand people in its 7 October attacks and took about 240 people hostage. Hamas-run health authorities claim Israeli attacks have since killed almost 56,000 people in Gaza.
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1:49
What’s happening to Palestine Action?
Faith continued: “When you scribble on something, or paint on it, it’s a non-violent protest and it shouldn’t be made at the same level as a violent protest – it is unjust.”
Ben Jamal, director of the Palestine Solidarity Campaign, backed Palestine Action’s use of non-violent protest.
Image: A bank damaged by Palestine Action
He told Sky News: “There has been a place for that in all political movements in history.
“In the struggle for the rights of black people in the US, in the struggle against apartheid in South Africa, in the struggle for women to have the vote, people took forms of non-violent direct action.
“Imagine if we had the current [situation] back in those days – we would have been proscribing the suffragettes, treating them as terrorists.”
Image: There was a pro-Israeli counter-protest in London
Others have welcomed the move. Lord Walney, who served as the government’s independent adviser on political violence, told Sky News the decision was “long overdue”.
“Palestine Action have acted as the enemy within which is why it’s right, now, to crack down on them,” he said.
“They have terrorised working people for a number of years and there’s a number of serious violent charges that are going through the court system at the moment.”
The UK government is expected to announce its decision early next week.