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Blood types, a critical factor in transfusion medicine, have been studied extensively since the early 20th century. The ABO blood group system, established by Austrian immunologist Dr. Karl Landsteiner in 1901, introduced the understanding of four main blood types: A, B, AB, and O. These discoveries, which earned Landsteiner the 1930 Nobel Prize in Physiology or Medicine, revolutionised the practice of blood transfusions. However, according to recent findings and expert input, it has been revealed that the complexity of blood types extends far beyond the ABO system and Rh factor classification.

The Basics of Blood Typing

According to studies, blood types are defined by antigens — proteins and sugars present on the surface of red blood cells. Dr. Emily Coberly, Divisional Chief Medical Officer at the American Red Cross, told Live Science that the ABO system is pivotal in transfusion compatibility. Individuals produce antibodies against antigens not present in their own blood type, leading to immune reactions if mismatched blood is transfused. The Rh factor, another major antigen, determines whether blood is classified as positive or negative. These components combine to create the eight primary blood groups.

Emergence of Rare Blood Types

Beyond the ABO and Rh classifications, more than 350 other antigens have been identified on red blood cells. The International Society of Blood Transfusion currently recognises 47 blood group systems, with additional discoveries continually expanding this number. Rare blood types, such as the McLeod phenotype and Bombay phenotype, arise from unique antigen combinations. These rare types can complicate transfusions for individuals with specific conditions like sickle cell disease, which predominantly affects African and Hispanic populations.

The Need for a Diverse Donor Pool

As per reports, maintaining a diverse blood donor base is essential. Coberly, in a statement, has stressed the importance of matching blood more closely for patients with rare blood types, ensuring safe and effective treatments. As per reports, researchers are also exploring innovations to create universal donor blood by modifying red blood cells or engineering them from scratch, aiming to overcome compatibility challenges.

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Quantum Tech Could Finally Let Astronomers Snap Direct Images of Earth-Like Exoplanets

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Quantum Tech Could Finally Let Astronomers Snap Direct Images of Earth-Like Exoplanets

A team of U.S.-based astronomers is building a new kind of coronagraph — one powered by quantum mechanics — that could enable direct imaging of Earth-like exoplanets previously considered too faint or too close to their host stars to detect. Traditional telescopes have advanced since Galileo’s time, with instruments like the James Webb Space Telescope (JWST) now capable of analysing distant planetary atmospheres. But even these devices generally are not able to capture images of planets and asteroids that orbit nearby bright stars, as their light is frequently drowned out. Now, a breakthrough could be in sight.

Quantum-Sensitive Coronagraph May Revolutionize Exoplanet Imaging With Sub-Diffraction Precision

As per a recent Space.com report, researchers from the University of Arizona and the University of Maryland have developed a “quantum-sensitive” coronagraph that filters starlight before it reaches the telescope’s detector. By exploiting differences in the spatial modes of photons — how light waves behave in space — the device physically separates planetary light from overwhelming stellar glare. “This method routes photons to different regions before they even hit the sensor,” one co-author explained, emphasising its superiority to digital image processing.

This experimental device uses a “spatial mode sorter”, a series of precision-crafted optical phase masks that redirect light waves from exoplanets, allowing astronomers to view them below the diffraction limit. Normally, achieving this resolution would require telescopes too massive for current spaceflight capabilities. But quantum engineering may bypass that need altogether, provided that light purity — known as mode fidelity — reaches the stringent 1-in-a-billion requirement needed to block star photons while preserving exoplanet signals.

In lab tests, researchers successfully simulated star-planet systems and demonstrated that their system could resolve a dim, Earth-like planet even when positioned one-tenth the distance modern coronagraphs can handle. At higher star-to-planet contrast ratios — up to 1,000:1 — the device maintained accuracy within a few percentage points of theoretical limits, showcasing its potential for space-based observatories.

The technology could augment missions like NASA’s upcoming Habitable Worlds Observatory, designed to detect biosignatures on exoplanets. While scientists caution that the method isn’t a standalone solution, they believe it could dramatically expand the toolkit for planetary discovery. The findings were published on April 22 in Optica.

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New Homo Erectus Fossils Reveal Ancient Migration Across Drowned Sundaland

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New Homo Erectus Fossils Reveal Ancient Migration Across Drowned Sundaland

Homo erectus, an extinct human ancestor is an important part of our evolutionary history. Emerging at least 2 million years ago, it was the first species to develop human-like body proportions and the first human species to migrate out of Africa, eventually finding its way to Southeast Asia. Homo erectus was first discovered in Java and was known as “Java Man” until the species was officially renamed. Long thought to have been isolated on the island of Java, two fossil fragments of a Homo erectus skull—which surfaced with recent ocean dredging in preparation for the construction of an artificial island—revealed that this hominin species migrated and spread throughout the islands when they could still walk over bridges of land.

The drowned Sundaland

According to four studies published in Quaternary Environments and Human, by archaeologist Harold Berghuis and his team, these lost lands, called drowned Sundaland, were once vast open plains interspersed with rivers around 140,000 years ago.

During the glacial period that chilled the Earth 140,000 years ago, sea levels in the Indonesian region of Sundaland were low enough for present-day islands to tower like mountain ranges with a lowland savannah stretching between them. It was an expanse of mostly dry grasslands with strips of forest edging the rivers, and animals like crocodiles, river sharks, elephants, hippos, rhinos, and Komodo dragons flourished in the region.

Hunting and Cultural exchanges

Berghuis and his team argue that these ancient rivers provided not just water, but sustenance through fruit-bearing trees, fish, shellfish, and edible plants. Tool marks on bones Fossils show that Homo erectus hunted river turtles and large terrestrial animals.

The hunting techniques observed, such as targeting animals in their prime, are typically associated with more modern humans, raising questions about whether this H. erectus group developed such strategies independently or learned them through cultural exchange with other human relatives like Denisovans or Neanderthals. H. erectus is believed to have survived on Java until about 117,000 years ago, well after it disappeared elsewhere in Asia.

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Einstein Probe Detects Mysterious X-ray Flare with Record-Long Emission

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Einstein Probe Detects Mysterious X-ray Flare with Record-Long Emission

Fast Evolving X-ray Transients (FEXTs) are intense bursts of soft X-ray emissions that can last for minutes to hours with a wide range of luminosities. Due to their enigmatic nature, FEXTs have been a importance for scientists. Einstein Probe (EP) is one of the crucial space telescopes for the search and investigation of FEXTs. An international team of astronomers using the Einstein Probe reports the discovery of a new peculiar fast-evolving X-transient. The newfound transient exhibits an unprecedentedly long-lasting X-ray emission.

A Puzzling Long-Lived X-ray Transient

The finding was detailed in a paper published May 12 on the arXiv preprint server. According to the published paper, the newfound peculiar FEXT, dubbed EP241021a, was detected on Oct 21, 2024, with the help of EP’s wide-field X-ray telescope (WXT). EP241021a was identified by WXT as an intense flare, which lasted for approximately 92 seconds and reached a luminosity of about one quindecillion erg/s. The X-ray spectrum of the flare was found to be relatively hard with a photon index of 1.8.

The team of astronomers, led by Xinwen Shu of the Anhui Normal University in China, has concluded that EP241021a is an extremely unusual transient mainly due to its extended emission period. Follow-up observations of the flare up to 79 days after its detection revealed that its X-ray light curve shows a nearly plateau phase for the first 7 days, which is followed by a steep decline during the period of about 30 days. Afterward, the X-ray emission rapidly drops under the detection level.

The researchers also detected significant multiwavelength signals associated with EP241021a. About 1.8 days after the initial X-ray detection, optical emissions were also detected. This emission is likely connected to the flare’s afterglow.

Possible origins

The origin of FEXTs is puzzling. Astronomers try to explain their origin take into account several scenarios; for instance, stellar flares, supernova shock breakouts, or long gamma-ray bursts (GRBs).
Trying to explain the origin of EP241021a, the authors of the paper favor two scenarios. These are: a magnetar engine, involving a highly magnetized neutron star, or a jetted tidal disruption event (TDE), where a star is consumed by a black hole.

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