He has not been charged with the killing of Mr Thompson, officials said on Monday.
Detectives from the New York City Police Department (NYPD) have travelled to Pennsylvania to question Mangione.
Here’s what we know about him so far…
Arrest
According to officials from the NYPD, Mangione was arrested in Altoona on Monday after a tip-off from a McDonald’s employee who recognised him from the police appeals.
Image: Luigi Mangione, 26, was found at a McDonald’s, after a worker recognised him and called the police
Altoona is around 230 miles to the west of New York and in the state of Pennsylvania.
According to police, he had a silencer and a gun “both consistent with the weapon used in the murder”.
They said the gun appeared to be a “ghost gun” – a type of weapon that can be assembled at home from parts and without a serial number – and that it was possibly made using a 3D printer.
Mangione also had a fake New Jersey ID – with the name Mark Rosario – matching a document used by the suspect to check into a hostel in the city before the attack, NYPD Commissioner Jessica Tisch told a press conference on Monday.
Image: Luigi Mangione had a fake New Jersey ID
He was found carrying a “handwritten document” which Ms Tisch said spoke “to both his motivation and mindset”.
NYPD chief of detectives Joseph Kenny said that from the document, it appeared the suspect had “some ill-will towards corporate America”.
Background
According to police, Mangione was born and raised in the state of Maryland and has links to San Francisco in California and Hawaii’s capital Honolulu.
His social media lists him as being from Towson, a well-to-do area to the north of the city of Baltimore. He is said to have attended Gilman school – a private all-boys school in the city.
Image: Luigi Mangione Pic: LinkedIn
Fees cost up to $37,000 (£29,000) depending on the age of the student and the school boasts an impressive list of alumni, including businessmen, NFL stars and former state senators.
After graduating in 2016, it appears Mangione went on to attend the University of Pennsylvania.
According to his social media, he studied computer science and during his time there launched a gaming research group named UPGRADE (UPenn Game Research and Development Environment).
He later co-founded his own computer game company, which focused on small, simplistic games.
According to his LinkedIn page, Mangione moved to California in 2020, where he worked for a digital retailing website for new and used cars.
Magione lists himself as from Honolulu on his LinkedIn page, while pictures shared on his public Instagram page show him on the island of Hawaii.
What about his social media presence?
Mangione appears to have an active social media presence.
One account, appearing under his name and picture on the X platform, regularly shares and reposts think pieces, with frequent topics such as artificial intelligence (AI), philosophy, and the future of humanity in a world of ever-more powerful technology.
Image: Luigi Mangione. Pic: Facebook
The account praised the book What’s Our Problem? by the popular American author Tim Urban – who often addresses such topics – in January 2024 saying he “believed it would go down in history as the most important philosophical text of the early 21st century”.
While the account does address political issues, it seemingly does not express views on the American healthcare and insurance system.
In another account matching his name and photograph on the user-generated book review site Goodreads, he appeared to give a four-star review to a text called Industrial Society and Its Future by Theodore Kaczynski.
The piece, which rallied against technological advancement, became known as the Unabomber Manifesto after its author began a nearly 20-year mail bombing campaign which he said was designed to protect nature.
Three people were killed and dozens others injured in the bombing campaign, which ended with his arrest in 1996.
In the review, the account seemingly run by Mangione wrote: “When all other forms of communication fail, violence is necessary to survive. You may not like his methods, but to see things from his perspective, it’s not terrorism, it’s war and revolution.
“‘Violence never solved anything’ is a statement uttered by cowards and predators.”
Brian Thompson shooting
Brian Thompson, 50, was the chief executive of UnitedHealthcare – the fourth-largest public company in the United States.
Image: Chief Executive Officer of UnitedHealthcare Brian Thompson.
Pic: Business Wire/AP
He was targeted by what experts claim was a “seasoned, professional killer”, who shot him on 4 December as he was walking into a Manhattan hotel where his company was holding a conference.
Investigators said last week the words “defend”, “deny”, and “depose” were written on the cases of bullets found at the scene, which are similar to the title of a book that criticises health insurance companies.
The shooting happened at 6.45am on Wednesday 4 December – just before sunrise.
Mr Thompson was in New York City for UnitedHealthcare’s annual investors conference, which was due to start at 8am.
Image: Police shared this picture of the suspect following the shooting. Pic: NYPD
As he walked towards the entrance of the Hilton hotel on Sixth Avenue, in Manhattan’s midtown, a gunman appeared from two parked cars behind him.
The suspect drew his weapon and fired at least three times at close range – around 15ft (4.6m) away from him on the pavement.
Mr Thompson was shot in the back and the calf and died from his injuries.
Image: A police officer stands near the scene where the CEO of United Healthcare Brian Thompson was shot. Pic: Reuters
UnitedHealthcare is the largest provider of Medicare Advantage plans in the US and manages insurance for employers and state and federally funded programmes.
It is the fourth largest public company in the country – behind Walmart, Amazon, and Apple.
Former US president Joe Biden has prostate cancer, his office has said.
The statement said Mr Biden, who left the White House in January, is reviewing options for treatment with his physicians.
It read: “Last week, President Joe Biden was seen for a new finding of a prostate nodule after experiencing increasing urinary symptoms.
“On Friday, he was diagnosed with prostate cancer, characterised by a Gleason score of 9 (Grade Group 5) with metastasis to the bone.
“While this represents a more aggressive form of the disease, the cancer appears to be hormone-sensitive which allows for effective management.
“The President and his family are reviewing treatment options with his physicians.”
Image: File pic: Reuters
According to Cancer Research UK, a Gleason score of 9 means the cancerous cells “look very abnormal” and the disease is “likely to grow quickly”.
More on Cancer
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A source familiar with Mr Biden and his family’s thinking has told Sky’s US partner network, NBC News, that the former president is considering “multiple treatment options” – including hormone treatment for the cancer.
They added he is at his home in Wilmington, Delaware, and that as of now, it is unclear where the former president will be treated.
Mr Biden, 82, was the oldest person to ever serve as president, with concerns about his health raised regularly during his campaign for re-election last year.
A Mexican navy ship has hit the Brooklyn Bridge during a promotional tour in New York City.
The New York Fire Department said authorities were responding to injuries but had no details about how many people might have been hurt or whether they were on the vessel or on the bridge.
Sky’s US partner network NBC News reports that at least three people were seriously injured in the incident.
The Mexican navy said in a post on X that the Cuauhtemoc, an academy training vessel, was damaged in the accident, which has prevented it from continuing its voyage.
Eyewitness video of the collision posted online showed the mast of the ship, which was flying a large Mexican flag, scraping the underneath of the bridge.
Image: Pic: AP
The vessel then drifted toward the edge of the river as onlookers scrambled away from shore.
The Mexican navy said the status of personnel and material was under review by naval and local authorities, which were providing assistance.
More on New York City
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The Cuauhtemoc is about 297ft long and 40ft wide, according to the Mexican navy. It sailed for the first time in 1982.
Image: Pic: AP
Each year, it sets out at the end of classes at the naval military school to finish cadets’ training.
It left the Mexican port of Acapulco, on the Pacific coast, on 6 April with 277 people onboard, the navy said at the time.
This breaking news story is being updated and more details will be published shortly.
One person has died in a bomb explosion near a reproductive health clinic in California, authorities have said.
The incident took place in Palm Springs, a city two hours east of Los Angeles, and is being investigated as a possible car explosion.
The city’s mayor Ron DeHarte said one person died in the blast, adding that the bomb was “either in or near” a vehicle. The deceased’s identity is not known, Palm Springs police said.
Dr Maher Abdallah, who runs the American Reproductive Centers clinic, told the Associated Press his facility was damaged but all staff were safe and accounted for.
The explosion damaged the office space where the practice conducts patient consultations, but the IVF lab and stored embryos were unharmed, he added.
“I really have no clue what happened,” he said. “Thank God today happened to be a day that we have no patients.”
Image: Debris covers the ground after the explosion. Pic: ABC7 Los Angeles/AP
In a statement posted on Facebook the clinic said it was “heartbroken” to learn someone died in the explosion and added: “Our deepest condolences go out to the individuals and families affected.”
It continued: “Our mission has always been to help build families, and in times like these, we are reminded of just how fragile and precious life is.
“In the face of this tragedy, we remain committed to creating hope – because we believe that healing begins with community, compassion, and care.
The clinic will be fully operational on Monday, it added.
“This moment has shaken us – but it has not stopped us. We will continue to serve with strength, love, and the hope that brings new life into the world,” the statement concluded.
Image: Pic: ABC7 Los Angeles/AP
The Palm Springs city government said in a post on Facebook that the explosion happened on North Indian Canyon Drive, near East Tachevah Drive, before 11am local time (6pm GMT).
A burned-out car can be seen in a parking lot behind the building in aerial footage.
The blast caved in the clinic’s roof and blew debris across four lanes of the road.
Another person said he was inside a cannabis dispensary nearby when he felt a massive explosion.
Nima Tabrizi said: “The building just shook, and we go outside and there’s massive cloud smoke.”
Investigators from the FBI and the Bureau of Alcohol, Tobacco, Firearms and Explosives are travelling to the scene to help assess what happened.
California governor Gavin Newsom has been briefed on the explosion, his press office said.