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Puberty blockers for under-18s with gender dysphoria will be banned indefinitely in the UK after experts warned of an “unacceptable safety risk”.

The government said that following recommendations from independent medical professionals, existing emergency measures banning the sale and supply of the drugs outside of clinical trials will stay in place.

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Health and Social Care Secretary Wes Streeting said there is a need to “act with caution” and “follow the expert advice” in caring for this “vulnerable group of young people”.

He said the Commission on Human Medicines (CHM) has found that the current prescribing and care pathway for gender dysphoria “presents an unacceptable safety risk for children and young people”.

He also referenced the findings of the Cass Review, which “raised safety concerns around the lack of evidence for these medical treatments”.

“We need to act with caution and care when it comes to this vulnerable group of young people, and follow the expert advice,” Mr Streeting said.

Mr Streeting added that the government is working with NHS England to set up new gender identity services for young people, following the closure of the much-scrutinised Tavistock centre, and would be setting up a clinical trial into the use of puberty blockers next year, “to establish a clear evidence base for the use of this medicine”.

Wes Streeting speaks to Sky News.
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Wes Streeting

He insisted the government’s decision was based on “evidence” and not “political pressure” , as he acknowledged that many young transgender people will be affected by the ban.

In a direct message to them, Mr Streeting spoke of his own struggles coming out as gay.

He said: “I know it’s not easy being a trans kid in our country today, the trans community is at the wrong end of all of the statistics for mental ill health, self-harm and suicide.

“I can’t pretend to know what that’s like, but I do know what it’s like to feel you have to bury a secret about yourself, to be afraid of who you are, to be bullied for it, and then to experience the liberating experience of coming out.

“I know it won’t feel like it based on the decisions I’m taking today, but I really do care about this and so does this government. I am determined to improve the quality of care and access to healthcare for all trans people.”

‘Unacceptable safety risk’

The CHM’s advice said that there is “currently an unacceptable safety risk in the continued prescription of puberty blockers to children”.

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‘Toxic debate’ around child gender ID

The commission recommended indefinite restrictions while work is done to ensure the safety of young people.

Puberty blockers pause the physical changes of puberty such as breast development or facial hair.

The NHS announced in March that children would no longer be prescribed them, after commissioning an independent review of gender identity services for children under 18 in 2020.

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The review followed a sharp rise in referrals to the Gender Identity Development Service (GIDS) – a specialised service for young people who experience difficulties in the development of their gender identity.

The review was led by Dr Hilary Cass, who concluded in a final report in April this year that there was “remarkably weak evidence” to support gender treatments for children.

Her report promoted the then-Conservative government to introduce a ban on puberty blockers for under-18s using emergency legislation, preventing the prescription of the medication from European or private prescribers and restricting NHS provision to within clinical trials.

A challenge to that ruling, brought by campaigners who said they were concerned for the welfare of young trans people, failed in July when the high court ruled that the ban was lawful.

While health is a devolved matter, the indefinite ban announced on Wednesday applies across the UK, the DHSC said.

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US Senator sets 2026 goal for two crypto bills

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US Senator sets 2026 goal for two crypto bills

US Senator sets 2026 goal for two crypto bills

Cynthia Lummis said she expects the CLARITY Act and GENIUS Act to pass through Congress and be ready for the president’s signature by the end of the year.

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US home mortgage regulator to recognize crypto assets in risk assessments

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US home mortgage regulator to recognize crypto assets in risk assessments

US home mortgage regulator to recognize crypto assets in risk assessments

The decision was announced Wednesday by FHFA director William J. Pulte, who said the directive aligns with US President Donald Trump’s crypto agenda.

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Starmer’s team ask Labour MPs to remove names from rebel amendment that could bring down welfare bill

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Starmer's team ask Labour MPs to remove names from rebel amendment that could bring down welfare bill

Cabinet ministers have been asking Labour MPs to take their name off a rebel amendment to the government’s controversial welfare bill, Sky News can reveal.

In an attempt to quell the mounting rebellion of more than 100 MPs across all wings of the party, cabinet ministers were instructed to ring around the signatories of the amendment in a bid to get them to back the welfare cuts ahead of a planned vote next Tuesday.

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Two Labour MPs said they had been asked if they would take their names off the amendment, while one was asked if they would be prepared to abstain on the bill next week.

One Labour MP said: “‘The more they tell people to take their names off, the more names are added on.”

Others were also told their actions could provoke a fresh leadership challenge and that they were aligning themselves with Nigel Farage in a bid to get them to back down.

“I had a conversation with a senior cabinet member yesterday who basically said if the government is defeated next week it will trigger a leadership contest,” a Labour MP said.

More on Benefits

“I can see how that might be the case but I would argue if that’s where we end up it’s because the government have allowed that to happen. The ball is very much in their court.

“By and large the rebels do not want this to be about leadership. We just want to government to listen.”

Another added that while they had not received a call from a cabinet minister, they knew “some colleagues are being told there will be a leadership challenge or a general election which is utter nonsense”, adding: “Everything is all over the place.”

The amendment, if passed, would effectively kill the government’s welfare reforms by failing to give it a second reading in the Commons.

What are the main changes in the welfare bill?

The most controversial elements of the government’s welfare bill are changes to PIP and Universal Credit.

PIP is money for people who have extra care needs or mobility needs as a result of a disability.

People who claim it – some of whom are in work – are awarded points depending on their ability to do certain activities, such as washing and preparing food, and this influences how much they will receive.

Under the plans, from November 2026, people will need to score a minimum of four points in at least one activity to qualify for the daily living element of PIP – instead of fewer points across a broader range of tasks the person needs help with.

The changes do not affect the mobility component of PIP.

And from April next year, the health element of Universal Credit will be frozen in cash terms for existing claimants at £97 per week until 2029/2030.

For new claimants, the health element of Universal Credit will be reduced to £50 per week.

However, ministers point to the fact that the Universal Credit standard allowance will increase from £92 per week in 2025-26 to £106 per week by 2029-30.

Overall, 3.2 million families are expected to lose an average of £1,720 by the end of 2030 due to the changes.

However, the government has stressed that these figures do not take into account the £1bn that is being put towards helping the long-term sick and disabled back into work.

It calls for a delay to the £5bn package to assess the impact of cuts to personal independence payments (PIP) and expresses concerns about the government’s own figures showing 250,000 people could be pushed into poverty – including 50,000 children.

The fact the amendment was tabled by Dame Meg Hillier, chair of the Treasury select committee, with the support of 12 other select committee chairs, has alarmed Downing Street – as has the sheer scale of the rebellion.

At least 123 Labour MPs have signed the public amendment, but Sky News understands more names are likely to appear in the coming days.

While Sir Keir Starmer and his deputy, Angela Rayner, have insisted the vote will go ahead next Tuesday, the decision to instruct cabinet ministers to call around colleagues suggests the government is concerned about potentially losing the vote.

‘The government is not listening’

A Labour MP who signed the amendment said most rebels wanted the government to pause the proposals pending a proper consultation.

They said the fact that the text of the bill had been published before the consultation had closed was proof the government was “not listening”.

Another MP said they had raised concerns that if constituents are moved from PIP to universal credit they could potentially exceed the benefits cap, which could disproportionally hit those living in cities where the cost of living is higher.

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“I can’t look at my constituents and say I’m confident this won’t negatively affect them,” they said.

The MP also criticised the government’s approach to keeping MPs on side, saying it had failed to make the case for reform consistently.

“The engagement stopped after the initial flurry of bad press. Now there is a small amount of activity before the vote. Ministers need to be out there; the PM needs to be out there.”

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Starmer faces welfare rebellion

Despite the growing rebellion, the prime minister has indicated he is not willing to offer concessions on the government’s welfare plans.

Asked by reporters at the NATO summit in the Netherlands if he was willing to make changes to the bill, Sir Keir said: “We have got to make the reforms to our system. It isn’t working as it is.

“It doesn’t work as it stands for people who desperately need help to get into work or for people who need protection. It is broken.

“We were elected in to change that which is broken, and that’s what we will do, and that’s why we will press ahead with reforms.”

Downing Street has been contacted for comment.

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